Click here to switch to the map view.

The map label for this gene is pgi

Identifier: 150006817

GI number: 150006817

Start: 158307

End: 159650

Strand: Reverse

Name: pgi

Synonym: BDI_0148

Alternate gene names: 150006817

Gene position: 159650-158307 (Counterclockwise)

Preceding gene: 150006818

Following gene: 150006816

Centisome position: 3.32

GC content: 45.01

Gene sequence:

>1344_bases
ATGAAAAACATCAGTTTAAACATCGACAAGGCTCTGGGCACTGTCTCCAAGGAACAGGTTTACGCTCAAGAGGCCAAGGC
AATGGAATGTATTGCCACATTACATAACGGTAACGGAGCAGGTAACGACTTTTTGGGTTGGTTGCATCTCCCCTCTTCTA
TCACGGACGCAGAGTTGGCCGACATCGAGAATACGGCGAACGTGCTTCGTTCTAAATGTGAGGTGGTCGTAGCCATTGGT
ATCGGTGGTAGCTATTTGGGTACCAAAGCGGTAGTAGAAGCGTTAAACAACAGCTTCGACTGGTTGCAAAACGACCGTAA
AAACCCGGTTATGTTATACGCCGGACACAATATCGGAGAGGATTATCTTTATGAATTAAGCGAAGTTTTGAAAGGTAAGC
AATTCGGTATTATCAATATCTCCAAGTCTGGTACGACTACAGAGCCGGCTTTGGCTTTCCGTATCTTGAAGAAACAATTG
GAAGATGCTGTTGGCAAGGAAGAGGCTAAACATCGTATCGTAGCTATCACGGACGCTAAGAGAGGCGCTTTGCGTACTTT
GGCAGATCAAGAAGGTTACAAGACTTTCATCATCCCTGATAACGTAGGTGGACGTTTCTCTGTTTTAACTCCGGTAGGTT
TGCTTCCGATCGCCGTGGCAGGTATCAGCATCCGCGACTTGGTTGCTGGAGCAGTTTCCATGGAAAAAGCTACAGACGCG
AGCGTTCCTTTCGCTGATAATATGGCCGCTATCTATGCCGCTACTCGTAATGAATTATATAAGAACGGTAAAAAGATTGA
GATCTTGGCTAACTTCCATCCGAAATTGCACTATATCGCAGAATGGTGGAAACAACTTTACGGAGAGAGCGAAGGTAAAG
ACGGTAAAGGTATTTTCCCAGCATCCGTAGATTTGACAACCGATTTGCATTCCATGGGGCAATGGATCCAAGACGGTGAG
CGTACGATTTTCGAAACGGTTATCTCCGTGGAAGCTACAGATCATAGCGTATTGGTCCCTACAGATGAAGCCGATTTAGA
TGGCTTGAACTTCTTGGCAGGCAAGCATGTAGACGAGGTAAACAAGATGGCCGAATTAGGTACTCAGTTGGCTCACGTAG
ATGGTGGTGTTCCTAATATTAAGGTTAATATGCCAGAAGTAAGCGCATTCTATATCGGTCAGTTGTTCTATTTCTTCGAG
AAAGCTTGCGGTATCAGTGGTTATATGTTAGGTGTGAATCCTTTCAATCAACCGGGTGTCGAGGCTTATAAGAAGAATAT
GTTCGCCCTGTTGAATAAGCCGGGATACGAGAAAGAAAGCGAAGCTATCAAAGCACGTTTATAA

Upstream 100 bases:

>100_bases
ACATGCCGATACTGGACGCTGTTTATGATATATTGTACGAGAAGAAATCGCCGACAACGGTCATTCGTCAATTAACGGAA
ACGTTTAAATAAAATAGCAT

Downstream 100 bases:

>100_bases
TACGATTTACCCCATAAAAAAACGGTTTTCTCATCACGAGGAAACCGTTTTTTCGTTTGAATAGTTTTTATTACTCATTT
AATTCTTTAAGTAAATCGCT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKNISLNIDKALGTVSKEQVYAQEAKAMECIATLHNGNGAGNDFLGWLHLPSSITDAELADIENTANVLRSKCEVVVAIG
IGGSYLGTKAVVEALNNSFDWLQNDRKNPVMLYAGHNIGEDYLYELSEVLKGKQFGIINISKSGTTTEPALAFRILKKQL
EDAVGKEEAKHRIVAITDAKRGALRTLADQEGYKTFIIPDNVGGRFSVLTPVGLLPIAVAGISIRDLVAGAVSMEKATDA
SVPFADNMAAIYAATRNELYKNGKKIEILANFHPKLHYIAEWWKQLYGESEGKDGKGIFPASVDLTTDLHSMGQWIQDGE
RTIFETVISVEATDHSVLVPTDEADLDGLNFLAGKHVDEVNKMAELGTQLAHVDGGVPNIKVNMPEVSAFYIGQLFYFFE
KACGISGYMLGVNPFNQPGVEAYKKNMFALLNKPGYEKESEAIKARL

Sequences:

>Translated_447_residues
MKNISLNIDKALGTVSKEQVYAQEAKAMECIATLHNGNGAGNDFLGWLHLPSSITDAELADIENTANVLRSKCEVVVAIG
IGGSYLGTKAVVEALNNSFDWLQNDRKNPVMLYAGHNIGEDYLYELSEVLKGKQFGIINISKSGTTTEPALAFRILKKQL
EDAVGKEEAKHRIVAITDAKRGALRTLADQEGYKTFIIPDNVGGRFSVLTPVGLLPIAVAGISIRDLVAGAVSMEKATDA
SVPFADNMAAIYAATRNELYKNGKKIEILANFHPKLHYIAEWWKQLYGESEGKDGKGIFPASVDLTTDLHSMGQWIQDGE
RTIFETVISVEATDHSVLVPTDEADLDGLNFLAGKHVDEVNKMAELGTQLAHVDGGVPNIKVNMPEVSAFYIGQLFYFFE
KACGISGYMLGVNPFNQPGVEAYKKNMFALLNKPGYEKESEAIKARL
>Mature_447_residues
MKNISLNIDKALGTVSKEQVYAQEAKAMECIATLHNGNGAGNDFLGWLHLPSSITDAELADIENTANVLRSKCEVVVAIG
IGGSYLGTKAVVEALNNSFDWLQNDRKNPVMLYAGHNIGEDYLYELSEVLKGKQFGIINISKSGTTTEPALAFRILKKQL
EDAVGKEEAKHRIVAITDAKRGALRTLADQEGYKTFIIPDNVGGRFSVLTPVGLLPIAVAGISIRDLVAGAVSMEKATDA
SVPFADNMAAIYAATRNELYKNGKKIEILANFHPKLHYIAEWWKQLYGESEGKDGKGIFPASVDLTTDLHSMGQWIQDGE
RTIFETVISVEATDHSVLVPTDEADLDGLNFLAGKHVDEVNKMAELGTQLAHVDGGVPNIKVNMPEVSAFYIGQLFYFFE
KACGISGYMLGVNPFNQPGVEAYKKNMFALLNKPGYEKESEAIKARL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Drosophila melanogaster, GI24651916, Length=410, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24651914, Length=410, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17737445, Length=410, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_PARD8 (A6L8C4)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301560.1
- ProteinModelPortal:   A6L8C4
- SMR:   A6L8C4
- STRING:   A6L8C4
- GeneID:   5305239
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0148
- eggNOG:   COG0166
- HOGENOM:   HBG615843
- OMA:   MMQGAAD
- ProtClustDB:   PRK14097
- BioCyc:   PDIS435591:BDI_0148-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 48734; Mature: 48734

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 289-289 ACT_SITE 310-310 ACT_SITE 424-424

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNISLNIDKALGTVSKEQVYAQEAKAMECIATLHNGNGAGNDFLGWLHLPSSITDAELA
CCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHH
DIENTANVLRSKCEVVVAIGIGGSYLGTKAVVEALNNSFDWLQNDRKNPVMLYAGHNIGE
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCCCCCEEEEECCCCCH
DYLYELSEVLKGKQFGIINISKSGTTTEPALAFRILKKQLEDAVGKEEAKHRIVAITDAK
HHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEECCC
RGALRTLADQEGYKTFIIPDNVGGRFSVLTPVGLLPIAVAGISIRDLVAGAVSMEKATDA
CCHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
SVPFADNMAAIYAATRNELYKNGKKIEILANFHPKLHYIAEWWKQLYGESEGKDGKGIFP
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
ASVDLTTDLHSMGQWIQDGERTIFETVISVEATDHSVLVPTDEADLDGLNFLAGKHVDEV
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCEEEEECCCCCCCCCHHHHCCCHHHH
NKMAELGTQLAHVDGGVPNIKVNMPEVSAFYIGQLFYFFEKACGISGYMLGVNPFNQPGV
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
EAYKKNMFALLNKPGYEKESEAIKARL
HHHHHHHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MKNISLNIDKALGTVSKEQVYAQEAKAMECIATLHNGNGAGNDFLGWLHLPSSITDAELA
CCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHH
DIENTANVLRSKCEVVVAIGIGGSYLGTKAVVEALNNSFDWLQNDRKNPVMLYAGHNIGE
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCCCCCEEEEECCCCCH
DYLYELSEVLKGKQFGIINISKSGTTTEPALAFRILKKQLEDAVGKEEAKHRIVAITDAK
HHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEECCC
RGALRTLADQEGYKTFIIPDNVGGRFSVLTPVGLLPIAVAGISIRDLVAGAVSMEKATDA
CCHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
SVPFADNMAAIYAATRNELYKNGKKIEILANFHPKLHYIAEWWKQLYGESEGKDGKGIFP
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
ASVDLTTDLHSMGQWIQDGERTIFETVISVEATDHSVLVPTDEADLDGLNFLAGKHVDEV
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCEEEEECCCCCCCCCHHHHCCCHHHH
NKMAELGTQLAHVDGGVPNIKVNMPEVSAFYIGQLFYFFEKACGISGYMLGVNPFNQPGV
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
EAYKKNMFALLNKPGYEKESEAIKARL
HHHHHHHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA