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The map label for this gene is nahA [H]

Identifier: 150006616

GI number: 150006616

Start: 5089308

End: 5091362

Strand: Reverse

Name: nahA [H]

Synonym: BVU_4136

Alternate gene names: 150006616

Gene position: 5091362-5089308 (Counterclockwise)

Preceding gene: 150006617

Following gene: 150006615

Centisome position: 98.61

GC content: 43.89

Gene sequence:

>2055_bases
ATGAGAAGATTGATTATATTGGCGGAAGTTGCATTGGGCTTGCTGTTTGCAAGTTGCACGAAAGAAGAGCAACGCACACT
TTCTGTTATTCCCGCACCATTAAAGGTGGAATTACAGCAGGAAGTGTTTTCATTGAATTCGGAAACAGGGTTATATATAG
ATGCGTCTGAGGGGGACAAGAAGATTTTGGAAGATTATCTGGTGGCTTCTTCCATGAATTTGAAACCGGTAATAGCAGAA
GAGGGACATAATGTTGTCTTGAAACAAGTGGCGGAACTGCCGGAGGTAAACTCTTCCGAGGGATATGTTCTGACGGTAAC
TCCTGATCAGGTACTTATTCGTGCAACTTCCGGGGCAGGATTGTTCTATGGAGTTCAGACTATGCTGCAAATGGTTGATG
AAAAAGGATTGCCGGCAGGAGTCATTACAGATGAACCCCGTTTTGCTTATCGTGGCTTTATGATGGATGTTTCCCGTCAT
TTCTTCGATAAGGAATTTATAAAAAAGCAGATGGATGCTTTGGCATATTATAAATTGAACCGTCTGCATCTGCATCTTAC
TGACGCTGCGGGCTGGCGTCTTGAAATAAAAAAATATCCCCGTCTGACAGAATTTGCGGCATGGCGTGAGTTTCCTACCT
GGAAAGAATGGTGGAATAACGGACGACGGTATGAAGAAGAAGGCAGTAAAGATGCTCACGGAGGTTATTATACTCAAGAT
GATATCCGCGAACTGGTGGCATACGCTCAGGAACGTTTTATTACTGTTATTCCTGAGATAGAGATGCCTGCGCATTCGGA
AGAAGTACTGACTGCTTATCCTGAGTTGTCTTGTACACACGAACCTTACAAACAAGCCGATTTCTGTGTCGGTAATGAAA
AGACTTTTGAGTTTCTGGAAAATGTGTTGACAGAGGTAATGGAACTTTTCCCGTCCGAATATATTCATATAGGAGGGGAT
GAGGCAGGTAAAGCCTCATGGCCCACTTGCAAACTGTGCCAGGCACGTATGAAAAAAGAAGGCTTGAAAGATGTGAACGA
GTTACAGAGTTATCTGATTCATCGTATTGAGGTCTTTTTGAATGCCCACGGACGTAAATTATTGGGTTGGGATGAAATAT
TGGAAGGTGGTTTGGCACCTAATGCCACTGTCATGTCATGGCGTGGCACGGAAGGGGGAATGAAAGCGGTTGATTCCGGC
CACATGGCTATTATGAGTCCGGGTGAGTTCTGCTATTTTGATTCTTATCAGGATGCTCCTGATTCCCAGCCGGAAGCAAT
AGGAGGCTATCTGCCTTTGTCCAAAGTTTATTCATTTAATCCTGTACCCGATACTTTGAGTGCGGATAAAGTCCAGTTGG
TGTATGGAGTACAAGCTAATTTATTCACAGAATATATTCCGACTCCGGAACATGCGGAAATGATGATTTATCCTCGTATT
CTTGCCTTGGCGGAAGTTGCTTGGAGTGCCCCTTCTGTGAAGAACTATGATGATTTTCATGTTCGTGCATTGAAAGAGGT
AGAGGCATTGAAAGCTGAAGGATACCATCCTTTTGAATTGAAAAATGAGATAGGAAATCGTCCGGGAGCGGATCAGCCCG
TACAGCATTTGGCAGTAGGTAAGAAAGTGGCTTACGGACCGGATGCCGCTTATTATCCCGGCTATTCGGCCGGTGGTGAC
AGTGCCTTGGTAGATGGTGTGATCGGAGGCTGGACTTATGGTGACAGGCGTTGGCAAGGTTTTATAGACAAGAAAAGAAT
GGATGTGACCATTGATATGGAAAAAGAAACAGAAATTCATTCTGTTGGAGCAGACTTTATGCAGGTGTGTGGACCTGAAG
TCTTTATGCCTTCAGAAGTGATCATTTCCGTTTCCAATGATGGTAAGGAGTTTACGGAACTGAAGCGCATGGAGCATAAA
GTAGTGAAGGATGACAAAGTGACTTTCATCAACTTTGGTTGGGAAGGAAATGCCAAAGCACGTTACATACGTTATCAGGC
ATCTTCGGGCGAATTCGGAGGTTTCTTGTTTACAGATGAAATTGTAGTGAAATAA

Upstream 100 bases:

>100_bases
CTGTAATAGTTTCGCAGGACGGATTTCATTACATTATTAATGGAGAATTGAAACCAGGCATTCGTACTAATGAAATTAAT
AGAATTAAAGAAAAGAGAAG

Downstream 100 bases:

>100_bases
TAGAACTTATATAAACAACAAATAGCATGAAGAAACAAATTTTGTTATCGGCTGTTCTGGCTTGTATCTCAGTTTTTTCT
GCGGCAGCACAGAAAGAGCC

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MRRLIILAEVALGLLFASCTKEEQRTLSVIPAPLKVELQQEVFSLNSETGLYIDASEGDKKILEDYLVASSMNLKPVIAE
EGHNVVLKQVAELPEVNSSEGYVLTVTPDQVLIRATSGAGLFYGVQTMLQMVDEKGLPAGVITDEPRFAYRGFMMDVSRH
FFDKEFIKKQMDALAYYKLNRLHLHLTDAAGWRLEIKKYPRLTEFAAWREFPTWKEWWNNGRRYEEEGSKDAHGGYYTQD
DIRELVAYAQERFITVIPEIEMPAHSEEVLTAYPELSCTHEPYKQADFCVGNEKTFEFLENVLTEVMELFPSEYIHIGGD
EAGKASWPTCKLCQARMKKEGLKDVNELQSYLIHRIEVFLNAHGRKLLGWDEILEGGLAPNATVMSWRGTEGGMKAVDSG
HMAIMSPGEFCYFDSYQDAPDSQPEAIGGYLPLSKVYSFNPVPDTLSADKVQLVYGVQANLFTEYIPTPEHAEMMIYPRI
LALAEVAWSAPSVKNYDDFHVRALKEVEALKAEGYHPFELKNEIGNRPGADQPVQHLAVGKKVAYGPDAAYYPGYSAGGD
SALVDGVIGGWTYGDRRWQGFIDKKRMDVTIDMEKETEIHSVGADFMQVCGPEVFMPSEVIISVSNDGKEFTELKRMEHK
VVKDDKVTFINFGWEGNAKARYIRYQASSGEFGGFLFTDEIVVK

Sequences:

>Translated_684_residues
MRRLIILAEVALGLLFASCTKEEQRTLSVIPAPLKVELQQEVFSLNSETGLYIDASEGDKKILEDYLVASSMNLKPVIAE
EGHNVVLKQVAELPEVNSSEGYVLTVTPDQVLIRATSGAGLFYGVQTMLQMVDEKGLPAGVITDEPRFAYRGFMMDVSRH
FFDKEFIKKQMDALAYYKLNRLHLHLTDAAGWRLEIKKYPRLTEFAAWREFPTWKEWWNNGRRYEEEGSKDAHGGYYTQD
DIRELVAYAQERFITVIPEIEMPAHSEEVLTAYPELSCTHEPYKQADFCVGNEKTFEFLENVLTEVMELFPSEYIHIGGD
EAGKASWPTCKLCQARMKKEGLKDVNELQSYLIHRIEVFLNAHGRKLLGWDEILEGGLAPNATVMSWRGTEGGMKAVDSG
HMAIMSPGEFCYFDSYQDAPDSQPEAIGGYLPLSKVYSFNPVPDTLSADKVQLVYGVQANLFTEYIPTPEHAEMMIYPRI
LALAEVAWSAPSVKNYDDFHVRALKEVEALKAEGYHPFELKNEIGNRPGADQPVQHLAVGKKVAYGPDAAYYPGYSAGGD
SALVDGVIGGWTYGDRRWQGFIDKKRMDVTIDMEKETEIHSVGADFMQVCGPEVFMPSEVIISVSNDGKEFTELKRMEHK
VVKDDKVTFINFGWEGNAKARYIRYQASSGEFGGFLFTDEIVVK
>Mature_684_residues
MRRLIILAEVALGLLFASCTKEEQRTLSVIPAPLKVELQQEVFSLNSETGLYIDASEGDKKILEDYLVASSMNLKPVIAE
EGHNVVLKQVAELPEVNSSEGYVLTVTPDQVLIRATSGAGLFYGVQTMLQMVDEKGLPAGVITDEPRFAYRGFMMDVSRH
FFDKEFIKKQMDALAYYKLNRLHLHLTDAAGWRLEIKKYPRLTEFAAWREFPTWKEWWNNGRRYEEEGSKDAHGGYYTQD
DIRELVAYAQERFITVIPEIEMPAHSEEVLTAYPELSCTHEPYKQADFCVGNEKTFEFLENVLTEVMELFPSEYIHIGGD
EAGKASWPTCKLCQARMKKEGLKDVNELQSYLIHRIEVFLNAHGRKLLGWDEILEGGLAPNATVMSWRGTEGGMKAVDSG
HMAIMSPGEFCYFDSYQDAPDSQPEAIGGYLPLSKVYSFNPVPDTLSADKVQLVYGVQANLFTEYIPTPEHAEMMIYPRI
LALAEVAWSAPSVKNYDDFHVRALKEVEALKAEGYHPFELKNEIGNRPGADQPVQHLAVGKKVAYGPDAAYYPGYSAGGD
SALVDGVIGGWTYGDRRWQGFIDKKRMDVTIDMEKETEIHSVGADFMQVCGPEVFMPSEVIISVSNDGKEFTELKRMEHK
VVKDDKVTFINFGWEGNAKARYIRYQASSGEFGGFLFTDEIVVK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=430, Percent_Identity=26.2790697674419, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI189181666, Length=453, Percent_Identity=25.8278145695364, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17569815, Length=420, Percent_Identity=26.1904761904762, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24657468, Length=438, Percent_Identity=24.8858447488584, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17647501, Length=438, Percent_Identity=24.8858447488584, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281365639, Length=438, Percent_Identity=24.6575342465753, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24657474, Length=438, Percent_Identity=24.6575342465753, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24653074, Length=437, Percent_Identity=26.5446224256293, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI45551090, Length=436, Percent_Identity=26.605504587156, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI17933586, Length=450, Percent_Identity=25.7777777777778, Blast_Score=106, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 77112; Mature: 77112

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLIILAEVALGLLFASCTKEEQRTLSVIPAPLKVELQQEVFSLNSETGLYIDASEGDK
CCEEEEHHHHHHHHHHHHHCCHHHCEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCH
KILEDYLVASSMNLKPVIAEEGHNVVLKQVAELPEVNSSEGYVLTVTPDQVLIRATSGAG
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCC
LFYGVQTMLQMVDEKGLPAGVITDEPRFAYRGFMMDVSRHFFDKEFIKKQMDALAYYKLN
HHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
RLHLHLTDAAGWRLEIKKYPRLTEFAAWREFPTWKEWWNNGRRYEEEGSKDAHGGYYTQD
EEEEEEECCCCCEEEECCCCCHHHHHHHHCCCCHHHHHCCCCEECCCCCCCCCCCCCCHH
DIRELVAYAQERFITVIPEIEMPAHSEEVLTAYPELSCTHEPYKQADFCVGNEKTFEFLE
HHHHHHHHHHHCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHH
NVLTEVMELFPSEYIHIGGDEAGKASWPTCKLCQARMKKEGLKDVNELQSYLIHRIEVFL
HHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAHGRKLLGWDEILEGGLAPNATVMSWRGTEGGMKAVDSGHMAIMSPGEFCYFDSYQDAP
HCCCCEEECHHHHHCCCCCCCCEEEEEECCCCCCHHCCCCCEEEECCCCEEEECCCCCCC
DSQPEAIGGYLPLSKVYSFNPVPDTLSADKVQLVYGVQANLFTEYIPTPEHAEMMIYPRI
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECHHHHHHHCCCCCCCCCEEHHHHH
LALAEVAWSAPSVKNYDDFHVRALKEVEALKAEGYHPFELKNEIGNRPGADQPVQHLAVG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHC
KKVAYGPDAAYYPGYSAGGDSALVDGVIGGWTYGDRRWQGFIDKKRMDVTIDMEKETEIH
CEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEECCCCCHHH
SVGADFMQVCGPEVFMPSEVIISVSNDGKEFTELKRMEHKVVKDDKVTFINFGWEGNAKA
HHCHHHHHHCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCE
RYIRYQASSGEFGGFLFTDEIVVK
EEEEEECCCCCCCCEEEECCEEEC
>Mature Secondary Structure
MRRLIILAEVALGLLFASCTKEEQRTLSVIPAPLKVELQQEVFSLNSETGLYIDASEGDK
CCEEEEHHHHHHHHHHHHHCCHHHCEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCH
KILEDYLVASSMNLKPVIAEEGHNVVLKQVAELPEVNSSEGYVLTVTPDQVLIRATSGAG
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCC
LFYGVQTMLQMVDEKGLPAGVITDEPRFAYRGFMMDVSRHFFDKEFIKKQMDALAYYKLN
HHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
RLHLHLTDAAGWRLEIKKYPRLTEFAAWREFPTWKEWWNNGRRYEEEGSKDAHGGYYTQD
EEEEEEECCCCCEEEECCCCCHHHHHHHHCCCCHHHHHCCCCEECCCCCCCCCCCCCCHH
DIRELVAYAQERFITVIPEIEMPAHSEEVLTAYPELSCTHEPYKQADFCVGNEKTFEFLE
HHHHHHHHHHHCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHH
NVLTEVMELFPSEYIHIGGDEAGKASWPTCKLCQARMKKEGLKDVNELQSYLIHRIEVFL
HHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAHGRKLLGWDEILEGGLAPNATVMSWRGTEGGMKAVDSGHMAIMSPGEFCYFDSYQDAP
HCCCCEEECHHHHHCCCCCCCCEEEEEECCCCCCHHCCCCCEEEECCCCEEEECCCCCCC
DSQPEAIGGYLPLSKVYSFNPVPDTLSADKVQLVYGVQANLFTEYIPTPEHAEMMIYPRI
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECHHHHHHHCCCCCCCCCEEHHHHH
LALAEVAWSAPSVKNYDDFHVRALKEVEALKAEGYHPFELKNEIGNRPGADQPVQHLAVG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHC
KKVAYGPDAAYYPGYSAGGDSALVDGVIGGWTYGDRRWQGFIDKKRMDVTIDMEKETEIH
CEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEECCCCCHHH
SVGADFMQVCGPEVFMPSEVIISVSNDGKEFTELKRMEHKVVKDDKVTFINFGWEGNAKA
HHCHHHHHHCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCE
RYIRYQASSGEFGGFLFTDEIVVK
EEEEEECCCCCCCCEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]