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The map label for this gene is nanM [H]

Identifier: 150006617

GI number: 150006617

Start: 5091359

End: 5092486

Strand: Reverse

Name: nanM [H]

Synonym: BVU_4137

Alternate gene names: 150006617

Gene position: 5092486-5091359 (Counterclockwise)

Preceding gene: 150006618

Following gene: 150006616

Centisome position: 98.63

GC content: 42.11

Gene sequence:

>1128_bases
ATGATCAGAAAAATAATATATGGCGTTTATGCGATACTGGGCATGATGACAATGGCTGCTTGTAGCGGTCAATCGGATGC
TTCTGAAATATCTCTTGAGAAAATGCATGGGTTCCCTACAGAGAATACCGGTTTTCTTAAGGGAGTTTCTGCATTATATG
CGGGAGTGATTGAAGGAAATTTGCTGATAGCCGGAGGTTGTAATTTCCCTGATATACCGGTAGCCGATGGAGGAAAAAAA
GCTTATTATCGGGATATATATATCGCCCCTTTGTCAAATGATACGGCTTTTGAGTGGAAGAAAATAGGCCAACTGCCTCA
GGCAGCAGCTTATGGAGTCACTATTTCTACTGAAAAAGGGTTAATTTGTGTTGGAGGGACTACGGCAACACACAGCTTGT
CTGATGTTTTTCTTTTATCTTTGCAAAAAGACACCTTGAAAAGAGATACTTTGCCCTCTTTGCCTGTAACTATGGATAAT
ATGGCAGGTGCATTAGTAGGACATTCACTATATATTGTCGGTGGAAATGTAAATGGCATTCCATCCTCGGCCATGTACAT
GCTTGATCTGTCGGATTTGTCTGGAGGATGGAAAAGAGAAACAGATATTCCGGGTGAACCCAGAGTACAATCTGTTTGCG
TGGCACAAGATGGAAAACTTTATGTGTGGGGGGGATTTGCCCCGGCTGTTGAAGGGCATCAGGCTTCTTTGTCAGTAGAT
GGATATATGTATTCTCCGGAAACGAAAGAATGGTCATCGGTTGCCACCCCGTATGATGCGGAAGGTAATGAGATCTCTTT
AGGTGGTGGAATGGGAACCTCTTTTGGCGAGGGTATGATATTGTGTGCCGGAGGAGTTGATAAGGATATATTCTTAAAAG
CTCTGCAAGGTATTTATGCGGGAAAAGAATATTTGTCACATCCTGTAGAGTGGTATCGGTTTAATAGAAACCTGCTGCTC
TATCATCCGCAGACGGATAAATGGACTACATTAGGCGAATATGAACAAGGTGCGCGTGCCGGAGCTGTAATAGTTTCGCA
GGACGGATTTCATTACATTATTAATGGAGAATTGAAACCAGGCATTCGTACTAATGAAATTAATAGAATTAAAGAAAAGA
GAAGATGA

Upstream 100 bases:

>100_bases
AGGAATGCTGTGTTTGCGTTGGTGCAATCCGTTTCTGGGGCAAGCGGGATGGCTGATTTGCTTTTGGCACACTTTTTATT
ATTTGCTTCACCATGAAAAC

Downstream 100 bases:

>100_bases
GAAGATTGATTATATTGGCGGAAGTTGCATTGGGCTTGCTGTTTGCAAGTTGCACGAAAGAAGAGCAACGCACACTTTCT
GTTATTCCCGCACCATTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminate mutarotase; Neu5Ac mutarotase; Sialic acid epimerase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIRKIIYGVYAILGMMTMAACSGQSDASEISLEKMHGFPTENTGFLKGVSALYAGVIEGNLLIAGGCNFPDIPVADGGKK
AYYRDIYIAPLSNDTAFEWKKIGQLPQAAAYGVTISTEKGLICVGGTTATHSLSDVFLLSLQKDTLKRDTLPSLPVTMDN
MAGALVGHSLYIVGGNVNGIPSSAMYMLDLSDLSGGWKRETDIPGEPRVQSVCVAQDGKLYVWGGFAPAVEGHQASLSVD
GYMYSPETKEWSSVATPYDAEGNEISLGGGMGTSFGEGMILCAGGVDKDIFLKALQGIYAGKEYLSHPVEWYRFNRNLLL
YHPQTDKWTTLGEYEQGARAGAVIVSQDGFHYIINGELKPGIRTNEINRIKEKRR

Sequences:

>Translated_375_residues
MIRKIIYGVYAILGMMTMAACSGQSDASEISLEKMHGFPTENTGFLKGVSALYAGVIEGNLLIAGGCNFPDIPVADGGKK
AYYRDIYIAPLSNDTAFEWKKIGQLPQAAAYGVTISTEKGLICVGGTTATHSLSDVFLLSLQKDTLKRDTLPSLPVTMDN
MAGALVGHSLYIVGGNVNGIPSSAMYMLDLSDLSGGWKRETDIPGEPRVQSVCVAQDGKLYVWGGFAPAVEGHQASLSVD
GYMYSPETKEWSSVATPYDAEGNEISLGGGMGTSFGEGMILCAGGVDKDIFLKALQGIYAGKEYLSHPVEWYRFNRNLLL
YHPQTDKWTTLGEYEQGARAGAVIVSQDGFHYIINGELKPGIRTNEINRIKEKRR
>Mature_375_residues
MIRKIIYGVYAILGMMTMAACSGQSDASEISLEKMHGFPTENTGFLKGVSALYAGVIEGNLLIAGGCNFPDIPVADGGKK
AYYRDIYIAPLSNDTAFEWKKIGQLPQAAAYGVTISTEKGLICVGGTTATHSLSDVFLLSLQKDTLKRDTLPSLPVTMDN
MAGALVGHSLYIVGGNVNGIPSSAMYMLDLSDLSGGWKRETDIPGEPRVQSVCVAQDGKLYVWGGFAPAVEGHQASLSVD
GYMYSPETKEWSSVATPYDAEGNEISLGGGMGTSFGEGMILCAGGVDKDIFLKALQGIYAGKEYLSHPVEWYRFNRNLLL
YHPQTDKWTTLGEYEQGARAGAVIVSQDGFHYIINGELKPGIRTNEINRIKEKRR

Specific function: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, whic

COG id: COG3055

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 Kelch repeats [H]

Homologues:

Organism=Escherichia coli, GI87082419, Length=229, Percent_Identity=30.5676855895196, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015915
- InterPro:   IPR006652
- InterPro:   IPR019936 [H]

Pfam domain/function: PF01344 Kelch_1 [H]

EC number: NA

Molecular weight: Translated: 40498; Mature: 40498

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKIIYGVYAILGMMTMAACSGQSDASEISLEKMHGFPTENTGFLKGVSALYAGVIEGN
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECC
LLIAGGCNFPDIPVADGGKKAYYRDIYIAPLSNDTAFEWKKIGQLPQAAAYGVTISTEKG
EEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHCCCCCHHHEEEEEECCCC
LICVGGTTATHSLSDVFLLSLQKDTLKRDTLPSLPVTMDNMAGALVGHSLYIVGGNVNGI
EEEECCCCCCCCCCEEEEEEECHHHHHHCCCCCCCEEHHHHHHHHHCCEEEEECCCCCCC
PSSAMYMLDLSDLSGGWKRETDIPGEPRVQSVCVAQDGKLYVWGGFAPAVEGHQASLSVD
CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEEC
GYMYSPETKEWSSVATPYDAEGNEISLGGGMGTSFGEGMILCAGGVDKDIFLKALQGIYA
CEEECCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
GKEYLSHPVEWYRFNRNLLLYHPQTDKWTTLGEYEQGARAGAVIVSQDGFHYIINGELKP
CHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCHHCCCCCCEEEEECCCEEEEEECCCCC
GIRTNEINRIKEKRR
CCCCHHHHHHHHHCC
>Mature Secondary Structure
MIRKIIYGVYAILGMMTMAACSGQSDASEISLEKMHGFPTENTGFLKGVSALYAGVIEGN
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECC
LLIAGGCNFPDIPVADGGKKAYYRDIYIAPLSNDTAFEWKKIGQLPQAAAYGVTISTEKG
EEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHCCCCCHHHEEEEEECCCC
LICVGGTTATHSLSDVFLLSLQKDTLKRDTLPSLPVTMDNMAGALVGHSLYIVGGNVNGI
EEEECCCCCCCCCCEEEEEEECHHHHHHCCCCCCCEEHHHHHHHHHCCEEEEECCCCCCC
PSSAMYMLDLSDLSGGWKRETDIPGEPRVQSVCVAQDGKLYVWGGFAPAVEGHQASLSVD
CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEEC
GYMYSPETKEWSSVATPYDAEGNEISLGGGMGTSFGEGMILCAGGVDKDIFLKALQGIYA
CEEECCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
GKEYLSHPVEWYRFNRNLLLYHPQTDKWTTLGEYEQGARAGAVIVSQDGFHYIINGELKP
CHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCHHCCCCCCEEEEECCCEEEEEECCCCC
GIRTNEINRIKEKRR
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA