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The map label for this gene is nagA [H]

Identifier: 150006613

GI number: 150006613

Start: 5083183

End: 5084415

Strand: Reverse

Name: nagA [H]

Synonym: BVU_4133

Alternate gene names: 150006613

Gene position: 5084415-5083183 (Counterclockwise)

Preceding gene: 150006614

Following gene: 150006607

Centisome position: 98.47

GC content: 45.9

Gene sequence:

>1233_bases
GTGAAAAAGTTGCTATTTTTGTTGGCAAATTTAATATGCCAATTAAAAATTCTAACTTATCATAGTATCATGTTGACCCA
AATCATTAACGCAAAGATTCTTACCCCACAGGGCTGGTTGAAGGACGGATCTGTCCTTATGCGCGACAATAAGATTTTAG
AAGTTACCAATTGTGATTTAGCTGTTATCGGAGCCGAGCTGATTGACGCTAAAGGTATGTATGTTGTTCCCGGTGGTGTG
GAAATCCATTGTCATGGTGGTGGTGGCGGTGATTTTATGGAAGGTACGGAAGAGGCTTTCCGTACAGCCATTAATGCTCA
CATGAAACATGGTACTACCAGTATTTTCCCAACGTTGTCTTCTTCTACCGTACCGATGATTGAGGCAGCTGCCGAAACTT
GTACCAGGTTGATGGCGGAACCGGACAGTCCGGTACTTGGTCTTCATCTTGAAGGGCATTACCTTAATATGAAGATGGCA
GGCGGTCAGATGCCTGAAAACATAAAAGACCCGGATCCGAAGGAATATATTCCTATTGTAGAGAAGTGGGGCTGTATCAA
GCGTTGGGATGCTGCACCCGAATTGCCGGGTGCCATGCAGTTTGGTAAGTATATCACAGGAAAAGGCATCTTGGCTTCTG
TGGCACATACACAGGCCGAATATGAAGATATCCGTGCAGCCTGGGAGTCCGGTTATTCTCATGCTACACATTTCTATAAT
GCGATGCCGGGCTTCCATAAGCGCCGTGAGTATAAATATGAAGGTACAGTAGAAAGTATCTATCTGATAGACGATATGAC
AGTGGAAGTGGTAGCCGATGGTATTCATGTTCCTCCTACTATCTTGCGCCTGATATATAAGATTAAGGGTGTGGAACGTG
CTTGTGTTATTACCGATGCTTTGGCATGTGCCGCCAGTGAAAGCAATGTAGCTTTTGACCCTCGTGTCATCATTGAGGAT
GGTGTGTGCAAACTGGCCGACCGTTCTGCTTTGGCAGGCAGTGTGGCTACCATGGACCGTTTGATCCGTACCTTGGTGCA
AAAGGCAGAAATCCCATTGGAAGATGCTGTCCGTATGGCTTCGGAAACTCCGTCCAGGATTATGGGAGTATATGACCGCA
AGGGCTCACTTCAGAAAGGCAAAGATGCCGATATCTTGATTCTTGACCAGGACTTGAATATCCGTGCCGTATGGGCAATG
GGCAAGCTGGTCGAAGGAACTTGTACTTTGTAA

Upstream 100 bases:

>100_bases
TTGTTTCAATTTCCACTATCTGTGCCCCGCTTGATTTTATTAAGCGGGGCTTATTTATTAAAAAAAGTTGGAAAATAATT
GGGGAAATCTGTTTTAGAAA

Downstream 100 bases:

>100_bases
GAACCGGCTGAATAAGAACGGAAACAGGACTTTATAAAATCTCCTTTCACACCAAACGGATTATAATTCTATTGATTTAC
AATTTGTTATGGTGAAAGGA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKKLLFLLANLICQLKILTYHSIMLTQIINAKILTPQGWLKDGSVLMRDNKILEVTNCDLAVIGAELIDAKGMYVVPGGV
EIHCHGGGGGDFMEGTEEAFRTAINAHMKHGTTSIFPTLSSSTVPMIEAAAETCTRLMAEPDSPVLGLHLEGHYLNMKMA
GGQMPENIKDPDPKEYIPIVEKWGCIKRWDAAPELPGAMQFGKYITGKGILASVAHTQAEYEDIRAAWESGYSHATHFYN
AMPGFHKRREYKYEGTVESIYLIDDMTVEVVADGIHVPPTILRLIYKIKGVERACVITDALACAASESNVAFDPRVIIED
GVCKLADRSALAGSVATMDRLIRTLVQKAEIPLEDAVRMASETPSRIMGVYDRKGSLQKGKDADILILDQDLNIRAVWAM
GKLVEGTCTL

Sequences:

>Translated_410_residues
MKKLLFLLANLICQLKILTYHSIMLTQIINAKILTPQGWLKDGSVLMRDNKILEVTNCDLAVIGAELIDAKGMYVVPGGV
EIHCHGGGGGDFMEGTEEAFRTAINAHMKHGTTSIFPTLSSSTVPMIEAAAETCTRLMAEPDSPVLGLHLEGHYLNMKMA
GGQMPENIKDPDPKEYIPIVEKWGCIKRWDAAPELPGAMQFGKYITGKGILASVAHTQAEYEDIRAAWESGYSHATHFYN
AMPGFHKRREYKYEGTVESIYLIDDMTVEVVADGIHVPPTILRLIYKIKGVERACVITDALACAASESNVAFDPRVIIED
GVCKLADRSALAGSVATMDRLIRTLVQKAEIPLEDAVRMASETPSRIMGVYDRKGSLQKGKDADILILDQDLNIRAVWAM
GKLVEGTCTL
>Mature_410_residues
MKKLLFLLANLICQLKILTYHSIMLTQIINAKILTPQGWLKDGSVLMRDNKILEVTNCDLAVIGAELIDAKGMYVVPGGV
EIHCHGGGGGDFMEGTEEAFRTAINAHMKHGTTSIFPTLSSSTVPMIEAAAETCTRLMAEPDSPVLGLHLEGHYLNMKMA
GGQMPENIKDPDPKEYIPIVEKWGCIKRWDAAPELPGAMQFGKYITGKGILASVAHTQAEYEDIRAAWESGYSHATHFYN
AMPGFHKRREYKYEGTVESIYLIDDMTVEVVADGIHVPPTILRLIYKIKGVERACVITDALACAASESNVAFDPRVIIED
GVCKLADRSALAGSVATMDRLIRTLVQKAEIPLEDAVRMASETPSRIMGVYDRKGSLQKGKDADILILDQDLNIRAVWAM
GKLVEGTCTL

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=416, Percent_Identity=26.2019230769231, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI224922791, Length=421, Percent_Identity=25.8907363420428, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1786892, Length=388, Percent_Identity=29.3814432989691, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17553768, Length=407, Percent_Identity=28.5012285012285, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19920392, Length=400, Percent_Identity=27, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281361140, Length=413, Percent_Identity=25.90799031477, Blast_Score=121, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 44965; Mature: 44965

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLFLLANLICQLKILTYHSIMLTQIINAKILTPQGWLKDGSVLMRDNKILEVTNCDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEECCCEEEEECCCE
AVIGAELIDAKGMYVVPGGVEIHCHGGGGGDFMEGTEEAFRTAINAHMKHGTTSIFPTLS
EEECHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SSTVPMIEAAAETCTRLMAEPDSPVLGLHLEGHYLNMKMAGGQMPENIKDPDPKEYIPIV
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCHHHCCHH
EKWGCIKRWDAAPELPGAMQFGKYITGKGILASVAHTQAEYEDIRAAWESGYSHATHFYN
HHCCCHHCCCCCCCCCCHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AMPGFHKRREYKYEGTVESIYLIDDMTVEVVADGIHVPPTILRLIYKIKGVERACVITDA
CCCCHHHHHCCCCCCCEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHH
LACAASESNVAFDPRVIIEDGVCKLADRSALAGSVATMDRLIRTLVQKAEIPLEDAVRMA
HHHHCCCCCCEECCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SETPSRIMGVYDRKGSLQKGKDADILILDQDLNIRAVWAMGKLVEGTCTL
HCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHCCCCCCC
>Mature Secondary Structure
MKKLLFLLANLICQLKILTYHSIMLTQIINAKILTPQGWLKDGSVLMRDNKILEVTNCDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEECCCEEEEECCCE
AVIGAELIDAKGMYVVPGGVEIHCHGGGGGDFMEGTEEAFRTAINAHMKHGTTSIFPTLS
EEECHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCC
SSTVPMIEAAAETCTRLMAEPDSPVLGLHLEGHYLNMKMAGGQMPENIKDPDPKEYIPIV
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCHHHCCHH
EKWGCIKRWDAAPELPGAMQFGKYITGKGILASVAHTQAEYEDIRAAWESGYSHATHFYN
HHCCCHHCCCCCCCCCCHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AMPGFHKRREYKYEGTVESIYLIDDMTVEVVADGIHVPPTILRLIYKIKGVERACVITDA
CCCCHHHHHCCCCCCCEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHH
LACAASESNVAFDPRVIIEDGVCKLADRSALAGSVATMDRLIRTLVQKAEIPLEDAVRMA
HHHHCCCCCCEECCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SETPSRIMGVYDRKGSLQKGKDADILILDQDLNIRAVWAMGKLVEGTCTL
HCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]