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The map label for this gene is nagC [H]

Identifier: 150006596

GI number: 150006596

Start: 5062710

End: 5063942

Strand: Reverse

Name: nagC [H]

Synonym: BVU_4116

Alternate gene names: 150006596

Gene position: 5063942-5062710 (Counterclockwise)

Preceding gene: 150006602

Following gene: 150006595

Centisome position: 98.08

GC content: 36.66

Gene sequence:

>1233_bases
TTGTGGACATTAACGGAATATTTTATTATGGGTGAGAATTTGTTGAAAGAAATTGAAAAGGGCTCAAAGATGGCTGTGAT
GAAGAAGAAAATCATTACCCATTATATTTATAATGGAAGCTCTACGATTACTGATTTAGCAAGAGAGATGGATTTAAGTG
TGCCTACAGTTACAAAATTCATTGATGAAATGTGTGAGGAAGGTTACATTAACGACTATGGAAAGCTGGAAACCAGTGGG
GGAAGACATCCCAGTTTGTATGGTTTGAATGCAGATTCCGGATATTTTGTAGGTGTTGAAGTGCGTCAGTTTTCCATTAA
CTTAGGGTTGATAAATTTTAAAGGAGATGTAGTTCAGCTAAAAATGAATGTTCCTTTTAAAGCGAAGAATACCCCTGAGA
GTTTAGACGAATTGTGTAAGTTGATTAAACATTTTCTTCAAAAAGTCAGTGTTGAGAAAGATAAGATATTAAATATTAAT
GTAAATCTTTCCGGGCGTGTGAATCCGGATTTGGGATATAGTTACAGTATATTCAATTTTGATGAGCGCCCGTTGACGGA
TGTCATATCAGAAAAGGTGGGTGGTTATCGTGTTTCTATTGATAACGACACTCGTGCTATGATTTACGGTGAGTATATGC
AAGGTGTTGTGAAAGGTGAGAAGAATATCATCTTTATCAATGTCAGTTGGGGATTGGGTATGGGAATTATCATTGATGGA
AAGATTTATAAAGGAAAATCTGGTTTCTCTGGCGAATTCGGGCATAATTTTGGATATGAGAATGAGATTATCTGCCATTG
TGGGAAAAAAGGATGCATAGAAACGGAAGTTTCGGGGGCTGCTTTGCATCGTATTCTGTTGGAACATATTAATAATGGTG
AAAACTCTATTATCTCCAATACCAAGAAAAATTTGGAAGATTTGACCTTGGATGATATCATTGATGCGGTAAATAAGGAA
GATTTGCTGTGTATTGAACTGGTGGAAGAAATCGGAGTGAAATTAGGTCGCCATGTAGCGGGACTTATTAATATATTTAA
TCCGGAGCTAGTCATTATTGGTGGTGCATTGTCACGTACAGGTGATTATTTGACACAACCCATCACTACAGCTATTCGAA
AATATACACTGAACTTGATGAACCGTGATTCTGTTATTGTAGAATCTAAATTGAAAGAAAGAGCCGGGATCATCGGTGCT
TGTATGTTGTCGCGCAGTAAACTGTTTGAATAA

Upstream 100 bases:

>100_bases
TGGAATTGTTACAAAAAATGATAATTAGCTTACATCTTCTAAAATAATTTTTGAAAATTCTCTTTAAATGTGATTTGATT
TCATAAAAAAATAACTATAT

Downstream 100 bases:

>100_bases
TATGTAGGTATTATAAAGTAAGAGATGAATTCATTACATGGTTCATCTCTTATATTGCCTTCTTGTTAAGTTTAACTCTG
AGCAAGCTCAATAAGTTTTT

Product: putative xylose repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MWTLTEYFIMGENLLKEIEKGSKMAVMKKKIITHYIYNGSSTITDLAREMDLSVPTVTKFIDEMCEEGYINDYGKLETSG
GRHPSLYGLNADSGYFVGVEVRQFSINLGLINFKGDVVQLKMNVPFKAKNTPESLDELCKLIKHFLQKVSVEKDKILNIN
VNLSGRVNPDLGYSYSIFNFDERPLTDVISEKVGGYRVSIDNDTRAMIYGEYMQGVVKGEKNIIFINVSWGLGMGIIIDG
KIYKGKSGFSGEFGHNFGYENEIICHCGKKGCIETEVSGAALHRILLEHINNGENSIISNTKKNLEDLTLDDIIDAVNKE
DLLCIELVEEIGVKLGRHVAGLINIFNPELVIIGGALSRTGDYLTQPITTAIRKYTLNLMNRDSVIVESKLKERAGIIGA
CMLSRSKLFE

Sequences:

>Translated_410_residues
MWTLTEYFIMGENLLKEIEKGSKMAVMKKKIITHYIYNGSSTITDLAREMDLSVPTVTKFIDEMCEEGYINDYGKLETSG
GRHPSLYGLNADSGYFVGVEVRQFSINLGLINFKGDVVQLKMNVPFKAKNTPESLDELCKLIKHFLQKVSVEKDKILNIN
VNLSGRVNPDLGYSYSIFNFDERPLTDVISEKVGGYRVSIDNDTRAMIYGEYMQGVVKGEKNIIFINVSWGLGMGIIIDG
KIYKGKSGFSGEFGHNFGYENEIICHCGKKGCIETEVSGAALHRILLEHINNGENSIISNTKKNLEDLTLDDIIDAVNKE
DLLCIELVEEIGVKLGRHVAGLINIFNPELVIIGGALSRTGDYLTQPITTAIRKYTLNLMNRDSVIVESKLKERAGIIGA
CMLSRSKLFE
>Mature_410_residues
MWTLTEYFIMGENLLKEIEKGSKMAVMKKKIITHYIYNGSSTITDLAREMDLSVPTVTKFIDEMCEEGYINDYGKLETSG
GRHPSLYGLNADSGYFVGVEVRQFSINLGLINFKGDVVQLKMNVPFKAKNTPESLDELCKLIKHFLQKVSVEKDKILNIN
VNLSGRVNPDLGYSYSIFNFDERPLTDVISEKVGGYRVSIDNDTRAMIYGEYMQGVVKGEKNIIFINVSWGLGMGIIIDG
KIYKGKSGFSGEFGHNFGYENEIICHCGKKGCIETEVSGAALHRILLEHINNGENSIISNTKKNLEDLTLDDIIDAVNKE
DLLCIELVEEIGVKLGRHVAGLINIFNPELVIIGGALSRTGDYLTQPITTAIRKYTLNLMNRDSVIVESKLKERAGIIGA
CMLSRSKLFE

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=384, Percent_Identity=26.0416666666667, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1787878, Length=370, Percent_Identity=23.2432432432432, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082127, Length=352, Percent_Identity=24.4318181818182, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081733, Length=218, Percent_Identity=25.2293577981651, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787363, Length=320, Percent_Identity=23.4375, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45769; Mature: 45769

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTLTEYFIMGENLLKEIEKGSKMAVMKKKIITHYIYNGSSTITDLAREMDLSVPTVTKF
CCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHH
IDEMCEEGYINDYGKLETSGGRHPSLYGLNADSGYFVGVEVRQFSINLGLINFKGDVVQL
HHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCEEEEEEEEEEEEEEEEEEECCCEEEE
KMNVPFKAKNTPESLDELCKLIKHFLQKVSVEKDKILNINVNLSGRVNPDLGYSYSIFNF
EECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEECC
DERPLTDVISEKVGGYRVSIDNDTRAMIYGEYMQGVVKGEKNIIFINVSWGLGMGIIIDG
CCCCHHHHHHHCCCCEEEEECCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEEEC
KIYKGKSGFSGEFGHNFGYENEIICHCGKKGCIETEVSGAALHRILLEHINNGENSIISN
EEEECCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHHHCCCCHHHHHC
TKKNLEDLTLDDIIDAVNKEDLLCIELVEEIGVKLGRHVAGLINIFNPELVIIGGALSRT
HHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCC
GDYLTQPITTAIRKYTLNLMNRDSVIVESKLKERAGIIGACMLSRSKLFE
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MWTLTEYFIMGENLLKEIEKGSKMAVMKKKIITHYIYNGSSTITDLAREMDLSVPTVTKF
CCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHH
IDEMCEEGYINDYGKLETSGGRHPSLYGLNADSGYFVGVEVRQFSINLGLINFKGDVVQL
HHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCEEEEEEEEEEEEEEEEEEECCCEEEE
KMNVPFKAKNTPESLDELCKLIKHFLQKVSVEKDKILNINVNLSGRVNPDLGYSYSIFNF
EECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEECC
DERPLTDVISEKVGGYRVSIDNDTRAMIYGEYMQGVVKGEKNIIFINVSWGLGMGIIIDG
CCCCHHHHHHHCCCCEEEEECCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEEEC
KIYKGKSGFSGEFGHNFGYENEIICHCGKKGCIETEVSGAALHRILLEHINNGENSIISN
EEEECCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHHHCCCCHHHHHC
TKKNLEDLTLDDIIDAVNKEDLLCIELVEEIGVKLGRHVAGLINIFNPELVIIGGALSRT
HHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCC
GDYLTQPITTAIRKYTLNLMNRDSVIVESKLKERAGIIGACMLSRSKLFE
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]