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The map label for this gene is trpB

Identifier: 150006567

GI number: 150006567

Start: 5029520

End: 5030719

Strand: Direct

Name: trpB

Synonym: BVU_4087

Alternate gene names: 150006567

Gene position: 5029520-5030719 (Clockwise)

Preceding gene: 150006566

Following gene: 150006568

Centisome position: 97.41

GC content: 47.83

Gene sequence:

>1200_bases
ATGAAAACTTATCAGGTAAACAAAGAAGGTTATTATGGCGAATTTGGAGGGGCGTATATTCCCGAAATCCTTCACCGCTG
TGTGGAAGAATTGCAGAATGCCTATTCCAAAGTATTGGAAAGTGAAGGATTCAAACAAGAATTCCACCAGTTACTACGCG
ACTATGTAGGACGCCCTTCACCTCTTTACCTGGCAAACCGGCTAAGCAAGAAATATGGCTGTAAGATCTACCTGAAACGT
GAAGATTTAAACCACACCGGAGCACATAAAATCAATAATGCCATCGGACAGGTGTTACTGGCAAAACGTATGGGGAAAAA
ACGTATCATTGCAGAAACCGGAGCTGGACAGCATGGGGTGGCCACCGCTACGGTATGCGCTTTGATGAACATGCAATGCA
TTGTTTACATGGGCAAGACCGATGTAGAACGCCAGCATATCAATGTAGAAAAGATGAAAATGCTGGGAGCCGAAGTCCGC
CCGGTCACTTCCGGCAACATGACACTGAAAGATGCTACAAACGAAGCCATCCGCGACTGGTGTTGCCACCCTGCCGATAC
TTACTATGTCATCGGCTCTACCGTAGGCCCTCATCCCTACCCTGATATGGTGGCACGTCTGCAATCCGTTATCAGCGAAG
AAATCAAAAAGCAGCTGAAAGAACAGGAAGGAAGGGAATATCCCGATTACTTGATGGCTTGTGTAGGAGGAGGAAGCAAT
GCGGCAGGAACCATTTATCACTATATAGATGATGAACGTGTGCAGATTGTCCTGGCCGAGGCAGGAGGCAAAGGTATAGA
CACCGGTTTCTCGGCCGCTACCATCCAACTGGGGAAAATGGGAATTATCCACGGAGCAAAGACCTTGGTTATCCAAAACG
AGGACGGACAAATAGAGGAACCTTACTCCATTTCTGCCGGTCTGGATTATCCGGGCATAGGACCCATGCATGCCAATCTG
GCCAAACAGCAACGCGCTTTGGTACTCGCCATAAACGATGATGAAGCCATCCGTGCCGCATTTGAGCTGACCCGGCTGGA
AGGTATCATTCCTGCATTGGAATCGGCTCATGCATTGGGAGCATTGGACAAAATGAGATTCAAGCCAACGGATATAGTGG
TTCTCACCGTATCAGGACGCGGAGATAAGGATATTGAAACCTACTTGAAAGAATCCGGCACAAGGACCTCCTTGCAATAA

Upstream 100 bases:

>100_bases
TATACCTGACATTCTAAAAGGATATTCAAACTGAAGGCCTGTCGTACTTACGACAGGCCTTTTTTCGTTAGTGCAATTAA
CATTAAAATATAGAACGACA

Downstream 100 bases:

>100_bases
CACATAGAAACCCATGAGAGCAAAAACCCTATACGGACAACTATAAACAGAAAAGAAACAATGAAAACTTTTACCTATAC
CACCCGATGCAAAACCATAC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKTYQVNKEGYYGEFGGAYIPEILHRCVEELQNAYSKVLESEGFKQEFHQLLRDYVGRPSPLYLANRLSKKYGCKIYLKR
EDLNHTGAHKINNAIGQVLLAKRMGKKRIIAETGAGQHGVATATVCALMNMQCIVYMGKTDVERQHINVEKMKMLGAEVR
PVTSGNMTLKDATNEAIRDWCCHPADTYYVIGSTVGPHPYPDMVARLQSVISEEIKKQLKEQEGREYPDYLMACVGGGSN
AAGTIYHYIDDERVQIVLAEAGGKGIDTGFSAATIQLGKMGIIHGAKTLVIQNEDGQIEEPYSISAGLDYPGIGPMHANL
AKQQRALVLAINDDEAIRAAFELTRLEGIIPALESAHALGALDKMRFKPTDIVVLTVSGRGDKDIETYLKESGTRTSLQ

Sequences:

>Translated_399_residues
MKTYQVNKEGYYGEFGGAYIPEILHRCVEELQNAYSKVLESEGFKQEFHQLLRDYVGRPSPLYLANRLSKKYGCKIYLKR
EDLNHTGAHKINNAIGQVLLAKRMGKKRIIAETGAGQHGVATATVCALMNMQCIVYMGKTDVERQHINVEKMKMLGAEVR
PVTSGNMTLKDATNEAIRDWCCHPADTYYVIGSTVGPHPYPDMVARLQSVISEEIKKQLKEQEGREYPDYLMACVGGGSN
AAGTIYHYIDDERVQIVLAEAGGKGIDTGFSAATIQLGKMGIIHGAKTLVIQNEDGQIEEPYSISAGLDYPGIGPMHANL
AKQQRALVLAINDDEAIRAAFELTRLEGIIPALESAHALGALDKMRFKPTDIVVLTVSGRGDKDIETYLKESGTRTSLQ
>Mature_399_residues
MKTYQVNKEGYYGEFGGAYIPEILHRCVEELQNAYSKVLESEGFKQEFHQLLRDYVGRPSPLYLANRLSKKYGCKIYLKR
EDLNHTGAHKINNAIGQVLLAKRMGKKRIIAETGAGQHGVATATVCALMNMQCIVYMGKTDVERQHINVEKMKMLGAEVR
PVTSGNMTLKDATNEAIRDWCCHPADTYYVIGSTVGPHPYPDMVARLQSVISEEIKKQLKEQEGREYPDYLMACVGGGSN
AAGTIYHYIDDERVQIVLAEAGGKGIDTGFSAATIQLGKMGIIHGAKTLVIQNEDGQIEEPYSISAGLDYPGIGPMHANL
AKQQRALVLAINDDEAIRAAFELTRLEGIIPALESAHALGALDKMRFKPTDIVVLTVSGRGDKDIETYLKESGTRTSLQ

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=380, Percent_Identity=51.3157894736842, Blast_Score=384, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321412, Length=379, Percent_Identity=50.6596306068602, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_BACV8 (A6L7M5)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001301311.1
- ProteinModelPortal:   A6L7M5
- SMR:   A6L7M5
- STRING:   A6L7M5
- GeneID:   5305046
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_4087
- NMPDR:   fig|435590.6.peg.3800
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43985; Mature: 43985

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYQVNKEGYYGEFGGAYIPEILHRCVEELQNAYSKVLESEGFKQEFHQLLRDYVGRPS
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
PLYLANRLSKKYGCKIYLKREDLNHTGAHKINNAIGQVLLAKRMGKKRIIAETGAGQHGV
CCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
ATATVCALMNMQCIVYMGKTDVERQHINVEKMKMLGAEVRPVTSGNMTLKDATNEAIRDW
HHHHHHHHHCCEEEEEECCCCCCHHHCCHHHHHHHCCCCCEECCCCEEEECCCHHHHHHH
CCHPADTYYVIGSTVGPHPYPDMVARLQSVISEEIKKQLKEQEGREYPDYLMACVGGGSN
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
AAGTIYHYIDDERVQIVLAEAGGKGIDTGFSAATIQLGKMGIIHGAKTLVIQNEDGQIEE
CCCEEEEEECCCEEEEEEEECCCCCCCCCCCCEEEEECCEEEEECCEEEEEECCCCCCCC
PYSISAGLDYPGIGPMHANLAKQQRALVLAINDDEAIRAAFELTRLEGIIPALESAHALG
CCEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDKMRFKPTDIVVLTVSGRGDKDIETYLKESGTRTSLQ
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKTYQVNKEGYYGEFGGAYIPEILHRCVEELQNAYSKVLESEGFKQEFHQLLRDYVGRPS
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
PLYLANRLSKKYGCKIYLKREDLNHTGAHKINNAIGQVLLAKRMGKKRIIAETGAGQHGV
CCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
ATATVCALMNMQCIVYMGKTDVERQHINVEKMKMLGAEVRPVTSGNMTLKDATNEAIRDW
HHHHHHHHHCCEEEEEECCCCCCHHHCCHHHHHHHCCCCCEECCCCEEEECCCHHHHHHH
CCHPADTYYVIGSTVGPHPYPDMVARLQSVISEEIKKQLKEQEGREYPDYLMACVGGGSN
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
AAGTIYHYIDDERVQIVLAEAGGKGIDTGFSAATIQLGKMGIIHGAKTLVIQNEDGQIEE
CCCEEEEEECCCEEEEEEEECCCCCCCCCCCCEEEEECCEEEEECCEEEEEECCCCCCCC
PYSISAGLDYPGIGPMHANLAKQQRALVLAINDDEAIRAAFELTRLEGIIPALESAHALG
CCEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDKMRFKPTDIVVLTVSGRGDKDIETYLKESGTRTSLQ
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA