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The map label for this gene is mpg1 [H]

Identifier: 150006518

GI number: 150006518

Start: 4971377

End: 4972417

Strand: Reverse

Name: mpg1 [H]

Synonym: BVU_4038

Alternate gene names: 150006518

Gene position: 4972417-4971377 (Counterclockwise)

Preceding gene: 150006519

Following gene: 150006517

Centisome position: 96.31

GC content: 40.92

Gene sequence:

>1041_bases
ATGAATTGCTCTCATATTATTCTCCAATCTTTCTCTATTATTGATGCCATTCGCTGCATCAATGAGATTCACAATGAACC
ACTGGTGCTCTTTGTGGTAGATGAGAACAAAAGGATGCAAGGTACCCTTACCGATGGTGATGTGCGTCGTGCCTTGATTA
AAGGTATAGATGTGGATGCTCCTATTAGTGAGGCCATGCATCGTAATTTTAACTTTTTACGTCGCGGAGTGAACGATAGA
GTGGAGGATATTCACCACCAACGTGATTTAAGGATGCGTTTGGTACCCATACTTGATGAAGAAAATCATATTTGCGAAAT
CATCAATTTGGAACATTATGTAACTAAATTGCCAATTGATGCTGTATTAATGGCCGGTGGTAAGGGGGAACGCCTTCGTC
CGTTAACGGAGAAAACTCCTAAGCCCCTAATTAAGGTAGGTGACAAGTGTATCATTGATTATAATATTGATCGTTTGCTT
TCATACGGTTTGAATCATATATCTGTAACGGTTAACTATCTTGGCGACCAGATTGAGGAACATTTCCGGGAGGAACGCGA
TGGGGTGAAGATAGTTACTGTGCGTGAACCGAAATATCTAGGTACCATTGGCAGTATCAAGTTCGTGGAAACTTTTTACA
ATGATACGGTGCTGGTAATGAACTCAGATCTCTTTACGAATATTGATTTTGAGGATTTTTTCCTTCATTTCTGTCAGCAT
GATGCCGACATGAGTGTGGCAGCTGTGCCCTACGTAGTGAAGGTGCCATACGGTGTGTTCAATCTCGAAGGACGAGAAAT
CAAGGGCGTTACCGAGAAACCTACCATCAGTTATTATGCAAACGCCGGTATATACCTTATCAAACGCAAATTGCTTGACC
TTATTCCTGATGATATCTTCTTTAATGCCACTGACTTCATGTATAAACTCATAGAACAGGGATACAAGGTGATTCGCTAT
CCTATTAGTGGATATTGGCTGGATATTGGTCAGCATGATGAATTGGCGAGAGCAAGAGAGATGGTGAAACATTTGAAATA
A

Upstream 100 bases:

>100_bases
ATGTTATGGATGATCTTCATTCAATAGATATTGATAGTATGTTTGACTGGTATATGGCGGAAAAGGTAATCAGTAGTCAT
CTTATTGAAAATTAATTTAT

Downstream 100 bases:

>100_bases
ATTTAAAATACAACATACAATGAAAGTAATAGCAGTAATTCCTGCGCGCTATAAGTCTACGCGTTTTGAAGGTAAACCGT
TAGTAAACCTTTGTGGTAAA

Product: nucleotidyltransferase family protein

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNCSHIILQSFSIIDAIRCINEIHNEPLVLFVVDENKRMQGTLTDGDVRRALIKGIDVDAPISEAMHRNFNFLRRGVNDR
VEDIHHQRDLRMRLVPILDEENHICEIINLEHYVTKLPIDAVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLL
SYGLNHISVTVNYLGDQIEEHFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNSDLFTNIDFEDFFLHFCQH
DADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYANAGIYLIKRKLLDLIPDDIFFNATDFMYKLIEQGYKVIRY
PISGYWLDIGQHDELARAREMVKHLK

Sequences:

>Translated_346_residues
MNCSHIILQSFSIIDAIRCINEIHNEPLVLFVVDENKRMQGTLTDGDVRRALIKGIDVDAPISEAMHRNFNFLRRGVNDR
VEDIHHQRDLRMRLVPILDEENHICEIINLEHYVTKLPIDAVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLL
SYGLNHISVTVNYLGDQIEEHFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNSDLFTNIDFEDFFLHFCQH
DADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYANAGIYLIKRKLLDLIPDDIFFNATDFMYKLIEQGYKVIRY
PISGYWLDIGQHDELARAREMVKHLK
>Mature_346_residues
MNCSHIILQSFSIIDAIRCINEIHNEPLVLFVVDENKRMQGTLTDGDVRRALIKGIDVDAPISEAMHRNFNFLRRGVNDR
VEDIHHQRDLRMRLVPILDEENHICEIINLEHYVTKLPIDAVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLL
SYGLNHISVTVNYLGDQIEEHFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNSDLFTNIDFEDFFLHFCQH
DADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYANAGIYLIKRKLLDLIPDDIFFNATDFMYKLIEQGYKVIRY
PISGYWLDIGQHDELARAREMVKHLK

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=226, Percent_Identity=28.7610619469027, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI11761619, Length=226, Percent_Identity=30.0884955752212, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI133931050, Length=231, Percent_Identity=25.974025974026, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320148, Length=227, Percent_Identity=28.6343612334802, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355443, Length=222, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24644084, Length=222, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 40001; Mature: 40001

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCSHIILQSFSIIDAIRCINEIHNEPLVLFVVDENKRMQGTLTDGDVRRALIKGIDVDA
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCC
PISEAMHRNFNFLRRGVNDRVEDIHHQRDLRMRLVPILDEENHICEIINLEHYVTKLPID
CHHHHHHCCHHHHHHCCCHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEHHHHHHHCCHH
AVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLLSYGLNHISVTVNYLGDQIEE
HEEEECCCCCCCCCCHHCCCCHHHHCCCEEEEECCHHHHHHCCCCEEEEEHHHHHHHHHH
HFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNSDLFTNIDFEDFFLHFCQH
HHHHHCCCEEEEEEECCCHHCCCCCHHHHHHHHCCEEEEEECCCEECCCHHHHHHHHHHC
DADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYANAGIYLIKRKLLDLIPDDIF
CCCCCEEECCEEEECCCCEEECCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHE
FNATDFMYKLIEQGYKVIRYPISGYWLDIGQHDELARAREMVKHLK
ECHHHHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNCSHIILQSFSIIDAIRCINEIHNEPLVLFVVDENKRMQGTLTDGDVRRALIKGIDVDA
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCC
PISEAMHRNFNFLRRGVNDRVEDIHHQRDLRMRLVPILDEENHICEIINLEHYVTKLPID
CHHHHHHCCHHHHHHCCCHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEHHHHHHHCCHH
AVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLLSYGLNHISVTVNYLGDQIEE
HEEEECCCCCCCCCCHHCCCCHHHHCCCEEEEECCHHHHHHCCCCEEEEEHHHHHHHHHH
HFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNSDLFTNIDFEDFFLHFCQH
HHHHHCCCEEEEEEECCCHHCCCCCHHHHHHHHCCEEEEEECCCEECCCHHHHHHHHHHC
DADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYANAGIYLIKRKLLDLIPDDIF
CCCCCEEECCEEEECCCCEEECCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHE
FNATDFMYKLIEQGYKVIRYPISGYWLDIGQHDELARAREMVKHLK
ECHHHHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]