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The map label for this gene is kpsU [H]

Identifier: 150006517

GI number: 150006517

Start: 4970605

End: 4971357

Strand: Reverse

Name: kpsU [H]

Synonym: BVU_4037

Alternate gene names: 150006517

Gene position: 4971357-4970605 (Counterclockwise)

Preceding gene: 150006518

Following gene: 150006516

Centisome position: 96.28

GC content: 36.25

Gene sequence:

>753_bases
ATGAAAGTAATAGCAGTAATTCCTGCGCGCTATAAGTCTACGCGTTTTGAAGGTAAACCGTTAGTAAACCTTTGTGGTAA
ACCTATGATTTGGTGGGTTCATCATCAGCTTTGTCAAGTAAAAGGATTGAGTGAAATTTATGTGGCAACGGATGATGAAC
GTATTAGAAAGGTTTGTTCGGATTATGGAATTAAATATGTGATGACTTCAGATAGTCATCCCACGCATCTTGATCGCTTG
GCTGAATTCGCCGAAAATATAGAGTCTGATTTTTATATTAATATTAATGGTGATGAACCTTTGATGATGCCCGAATATGT
AGAACGACTTTTACCTACTTCCGACTTGAATCCTGTTGATTTTTATTTTGCTAATGCTATGACTAAAATAAAAAAGACAG
TGGAGGTGGCGGACATTTCTCGTATAAAGGTGGTAACGGATAATTTAGGATATGCAATGTATATGGCTAGGACTCCTATT
CCATATCCAAAGGCCAGCTCGGATTTTGACTATATGAAATTTGTTGGAATACAATGTTTCTCACGTTCTGCCTTGCTTTT
CTGCAAGGATAATAAACGTGGAAAAATTGAAAGTATAGAGGATATTGACGAATATCGTTTTTTGGAAAACGGAAAAAAAA
TAAAGTTTGTAGAGATTCCAGCTGAAACTTTATCTGTAGATACGCAGGCTGATGTGAAAATTGTGACAGAAGTCTTAGAG
CGCAGGGTTAAAAATAAGGAGATCGTATTATGA

Upstream 100 bases:

>100_bases
CCTATTAGTGGATATTGGCTGGATATTGGTCAGCATGATGAATTGGCGAGAGCAAGAGAGATGGTGAAACATTTGAAATA
AATTTAAAATACAACATACA

Downstream 100 bases:

>100_bases
GCAAAATCCAACTATTAGATTGTACTTTGCGTGATGGAGGGTACATCAATAATTTCCGATTCGGTAAATATGCCATACGG
AAAATTCTTCAACAACTGAC

Product: putative CMP-KDO synthetase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKVIAVIPARYKSTRFEGKPLVNLCGKPMIWWVHHQLCQVKGLSEIYVATDDERIRKVCSDYGIKYVMTSDSHPTHLDRL
AEFAENIESDFYININGDEPLMMPEYVERLLPTSDLNPVDFYFANAMTKIKKTVEVADISRIKVVTDNLGYAMYMARTPI
PYPKASSDFDYMKFVGIQCFSRSALLFCKDNKRGKIESIEDIDEYRFLENGKKIKFVEIPAETLSVDTQADVKIVTEVLE
RRVKNKEIVL

Sequences:

>Translated_250_residues
MKVIAVIPARYKSTRFEGKPLVNLCGKPMIWWVHHQLCQVKGLSEIYVATDDERIRKVCSDYGIKYVMTSDSHPTHLDRL
AEFAENIESDFYININGDEPLMMPEYVERLLPTSDLNPVDFYFANAMTKIKKTVEVADISRIKVVTDNLGYAMYMARTPI
PYPKASSDFDYMKFVGIQCFSRSALLFCKDNKRGKIESIEDIDEYRFLENGKKIKFVEIPAETLSVDTQADVKIVTEVLE
RRVKNKEIVL
>Mature_250_residues
MKVIAVIPARYKSTRFEGKPLVNLCGKPMIWWVHHQLCQVKGLSEIYVATDDERIRKVCSDYGIKYVMTSDSHPTHLDRL
AEFAENIESDFYININGDEPLMMPEYVERLLPTSDLNPVDFYFANAMTKIKKTVEVADISRIKVVTDNLGYAMYMARTPI
PYPKASSDFDYMKFVGIQCFSRSALLFCKDNKRGKIESIEDIDEYRFLENGKKIKFVEIPAETLSVDTQADVKIVTEVLE
RRVKNKEIVL

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=248, Percent_Identity=30.6451612903226, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28829; Mature: 28829

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIAVIPARYKSTRFEGKPLVNLCGKPMIWWVHHQLCQVKGLSEIYVATDDERIRKVCS
CEEEEEECCCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
DYGIKYVMTSDSHPTHLDRLAEFAENIESDFYININGDEPLMMPEYVERLLPTSDLNPVD
HCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHH
FYFANAMTKIKKTVEVADISRIKVVTDNLGYAMYMARTPIPYPKASSDFDYMKFVGIQCF
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHC
SRSALLFCKDNKRGKIESIEDIDEYRFLENGKKIKFVEIPAETLSVDTQADVKIVTEVLE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCHHHHHHHHHH
RRVKNKEIVL
HHHCCCCCCC
>Mature Secondary Structure
MKVIAVIPARYKSTRFEGKPLVNLCGKPMIWWVHHQLCQVKGLSEIYVATDDERIRKVCS
CEEEEEECCCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
DYGIKYVMTSDSHPTHLDRLAEFAENIESDFYININGDEPLMMPEYVERLLPTSDLNPVD
HCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHH
FYFANAMTKIKKTVEVADISRIKVVTDNLGYAMYMARTPIPYPKASSDFDYMKFVGIQCF
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHC
SRSALLFCKDNKRGKIESIEDIDEYRFLENGKKIKFVEIPAETLSVDTQADVKIVTEVLE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCCHHHHHHHHHH
RRVKNKEIVL
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8397187; 7875563; 8706906 [H]