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The map label for this gene is ybdR [H]

Identifier: 150006259

GI number: 150006259

Start: 4656938

End: 4657984

Strand: Reverse

Name: ybdR [H]

Synonym: BVU_3770

Alternate gene names: 150006259

Gene position: 4657984-4656938 (Counterclockwise)

Preceding gene: 150006264

Following gene: 150006258

Centisome position: 90.22

GC content: 45.37

Gene sequence:

>1047_bases
ATGTTGGCATATACTTATATTAAACAGGGAAAATTTGAATTGATAGAGAAACCGAAGCCTGAGTTGAGAGACTCGCGTGA
TGCTATTGTGCGCGTTACTCTCGGGAGTATTTGTACCAGTGACTTGCATATTAAACATGGTGGTGTGCCACGTGCTGTTC
CCGGAATAACAGTGGGGCATGAAATGGTGGGTATTGTGGAGCAGACAGGACGTGATGTTAAATTAGTCAAACCAGGCGAT
CGAGTTACCGTCAATGTGGAAACCTTTTGTGGAGAATGTTTTTTTTGCCGGCATAGATATGTGAATAATTGTGCTGATCC
TAATGGGGGATGGGCCTTGGGATGTCGGATTGATGGGGGGCAGACGGAGTATGTTCGCGTACCTTATGCTGATCAAGGCT
TGAATCTCATTCCCGATTCCGTGAGTGATGAGCAAGCTTTGTTTGTAGGAGATATCCTTGCTACAGGATTTTGGGCTGCT
CGCATTTCGGAGATTACCGAAGAAGACACGGTGCTTGTCATTGGTGCGGGACCTACGGGAATCTGTACTTTGCTTTGTGT
GATGCTGAGAAAGCCGCAGCGCATTGTTGTTTGTGAACAATCCTCTGAAAGAATTCGGTTTGTTAGGGAACATTATCCGC
AGGTAGAAGTTGTCACTCCAGAAGAATGTAAGGAATTTGTATTGCAAAGTAGTCCACACGGTGGTGCGGATGTAGTTTTT
GAAGTGGCAGGAGGGGAGGATACATTTCGCTTGGCATGGGAATGTGCGCGCCCTAATGCTGTCGTTATTTTGGTGGCTCT
TTATGACCGTCCTCAGATTCTTCCTTTGCCGGATATGTATGGAAAGAATCTAACCTTCAAAACTGGTGGCGTAGATGGTT
GCGATTGTGCTGAGATACTTCGCTTGATAGAGATGGGAAAAATAGATACCACTCCACTAATTACACATCGTTTCCCGCTA
GATCAGATAGAAACGGCTTACCAGATTTTTGAGAACCGACAAGATGGAGTGATAAAAGTAGCTGTGACAATGGAGGCTGG
AATGTAG

Upstream 100 bases:

>100_bases
GAAAGCCATTTTGTCAGCAAATGGTGGCTGTTATTTATGTTTGTATATTATCTTTGCGTCGTTTTATAAAGATAATCATT
AAAGAAGAAAAGGAAATATC

Downstream 100 bases:

>100_bases
ATTAAAAGCAATGAAATAGTATAATATAAGAGTGTATGCCTATTATTGAAATATCATCATTGACACATCCCGGAGTGGAT
GTTTTCTGCATGTTGACGGA

Product: putative zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MLAYTYIKQGKFELIEKPKPELRDSRDAIVRVTLGSICTSDLHIKHGGVPRAVPGITVGHEMVGIVEQTGRDVKLVKPGD
RVTVNVETFCGECFFCRHRYVNNCADPNGGWALGCRIDGGQTEYVRVPYADQGLNLIPDSVSDEQALFVGDILATGFWAA
RISEITEEDTVLVIGAGPTGICTLLCVMLRKPQRIVVCEQSSERIRFVREHYPQVEVVTPEECKEFVLQSSPHGGADVVF
EVAGGEDTFRLAWECARPNAVVILVALYDRPQILPLPDMYGKNLTFKTGGVDGCDCAEILRLIEMGKIDTTPLITHRFPL
DQIETAYQIFENRQDGVIKVAVTMEAGM

Sequences:

>Translated_348_residues
MLAYTYIKQGKFELIEKPKPELRDSRDAIVRVTLGSICTSDLHIKHGGVPRAVPGITVGHEMVGIVEQTGRDVKLVKPGD
RVTVNVETFCGECFFCRHRYVNNCADPNGGWALGCRIDGGQTEYVRVPYADQGLNLIPDSVSDEQALFVGDILATGFWAA
RISEITEEDTVLVIGAGPTGICTLLCVMLRKPQRIVVCEQSSERIRFVREHYPQVEVVTPEECKEFVLQSSPHGGADVVF
EVAGGEDTFRLAWECARPNAVVILVALYDRPQILPLPDMYGKNLTFKTGGVDGCDCAEILRLIEMGKIDTTPLITHRFPL
DQIETAYQIFENRQDGVIKVAVTMEAGM
>Mature_348_residues
MLAYTYIKQGKFELIEKPKPELRDSRDAIVRVTLGSICTSDLHIKHGGVPRAVPGITVGHEMVGIVEQTGRDVKLVKPGD
RVTVNVETFCGECFFCRHRYVNNCADPNGGWALGCRIDGGQTEYVRVPYADQGLNLIPDSVSDEQALFVGDILATGFWAA
RISEITEEDTVLVIGAGPTGICTLLCVMLRKPQRIVVCEQSSERIRFVREHYPQVEVVTPEECKEFVLQSSPHGGADVVF
EVAGGEDTFRLAWECARPNAVVILVALYDRPQILPLPDMYGKNLTFKTGGVDGCDCAEILRLIEMGKIDTTPLITHRFPL
DQIETAYQIFENRQDGVIKVAVTMEAGM

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=340, Percent_Identity=26.1764705882353, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI34577061, Length=349, Percent_Identity=24.9283667621776, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4501929, Length=350, Percent_Identity=25.4285714285714, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4501933, Length=349, Percent_Identity=24.0687679083095, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI71743840, Length=357, Percent_Identity=24.0896358543417, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI262073058, Length=357, Percent_Identity=24.0896358543417, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI71565154, Length=365, Percent_Identity=23.2876712328767, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786825, Length=384, Percent_Identity=30.7291666666667, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1787863, Length=355, Percent_Identity=26.7605633802817, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790045, Length=333, Percent_Identity=26.7267267267267, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI226510992, Length=329, Percent_Identity=26.4437689969605, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082125, Length=326, Percent_Identity=25.7668711656442, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788075, Length=356, Percent_Identity=26.4044943820225, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790718, Length=313, Percent_Identity=24.2811501597444, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788073, Length=346, Percent_Identity=24.8554913294798, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788407, Length=328, Percent_Identity=24.6951219512195, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786552, Length=338, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=341, Percent_Identity=25.5131964809384, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=337, Percent_Identity=26.1127596439169, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25146526, Length=361, Percent_Identity=25.7617728531856, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71997431, Length=361, Percent_Identity=25.4847645429363, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565904, Length=346, Percent_Identity=25.4335260115607, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=336, Percent_Identity=25.297619047619, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319258, Length=386, Percent_Identity=26.4248704663212, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=366, Percent_Identity=25.4098360655738, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319955, Length=336, Percent_Identity=23.2142857142857, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=336, Percent_Identity=23.2142857142857, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319257, Length=389, Percent_Identity=25.706940874036, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17137530, Length=342, Percent_Identity=26.6081871345029, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17737897, Length=342, Percent_Identity=26.6081871345029, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221457811, Length=338, Percent_Identity=23.9644970414201, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45550770, Length=338, Percent_Identity=23.9644970414201, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45551930, Length=338, Percent_Identity=23.9644970414201, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17737895, Length=356, Percent_Identity=24.7191011235955, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38460; Mature: 38460

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAYTYIKQGKFELIEKPKPELRDSRDAIVRVTLGSICTSDLHIKHGGVPRAVPGITVGH
CEEEEEECCCCHHHHCCCCHHHCCCCCEEEEEEEHHHCCCCEEEECCCCCCCCCCCEECH
EMVGIVEQTGRDVKLVKPGDRVTVNVETFCGECFFCRHRYVNNCADPNGGWALGCRIDGG
HHHHHHHHCCCEEEEECCCCEEEEEEHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCC
QTEYVRVPYADQGLNLIPDSVSDEQALFVGDILATGFWAARISEITEEDTVLVIGAGPTG
CEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCHH
ICTLLCVMLRKPQRIVVCEQSSERIRFVREHYPQVEVVTPEECKEFVLQSSPHGGADVVF
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCCCCEEEE
EVAGGEDTFRLAWECARPNAVVILVALYDRPQILPLPDMYGKNLTFKTGGVDGCDCAEIL
EEECCCCEEEEEEEECCCCEEEEEEEECCCCCEEECCHHCCCCEEEECCCCCCCCHHHHH
RLIEMGKIDTTPLITHRFPLDQIETAYQIFENRQDGVIKVAVTMEAGM
HHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MLAYTYIKQGKFELIEKPKPELRDSRDAIVRVTLGSICTSDLHIKHGGVPRAVPGITVGH
CEEEEEECCCCHHHHCCCCHHHCCCCCEEEEEEEHHHCCCCEEEECCCCCCCCCCCEECH
EMVGIVEQTGRDVKLVKPGDRVTVNVETFCGECFFCRHRYVNNCADPNGGWALGCRIDGG
HHHHHHHHCCCEEEEECCCCEEEEEEHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCC
QTEYVRVPYADQGLNLIPDSVSDEQALFVGDILATGFWAARISEITEEDTVLVIGAGPTG
CEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCHH
ICTLLCVMLRKPQRIVVCEQSSERIRFVREHYPQVEVVTPEECKEFVLQSSPHGGADVVF
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCCCCEEEE
EVAGGEDTFRLAWECARPNAVVILVALYDRPQILPLPDMYGKNLTFKTGGVDGCDCAEIL
EEECCCCEEEEEEEECCCCEEEEEEEECCCCCEEECCHHCCCCEEEECCCCCCCCHHHHH
RLIEMGKIDTTPLITHRFPLDQIETAYQIFENRQDGVIKVAVTMEAGM
HHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]