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The map label for this gene is ntpI [H]

Identifier: 150006058

GI number: 150006058

Start: 4419703

End: 4421508

Strand: Reverse

Name: ntpI [H]

Synonym: BVU_3562

Alternate gene names: 150006058

Gene position: 4421508-4419703 (Counterclockwise)

Preceding gene: 150006059

Following gene: 150006057

Centisome position: 85.64

GC content: 42.8

Gene sequence:

>1806_bases
ATGATTACAAAAATGAAGAAGTTGACTTTCCTTATTTATCATAAGGACTATGAATGTTTCCTGCAAAATATCCGTGATTT
GGGCGTAGTCCACGTGGCGGAAAAAGCGCAGGGGACAGCGGAGAATACCGAACTTCAAGAGAGCATCCGTCTGTCCGACC
ACTATGCTTCAACTATTAAGTTTTTGCAAGGTTTTAATGTTGAACTGCAAGAACAGAAGGGGGATACAGCCCGTGGAGAG
AAAGCGTTGGAGGAAGTGGAGGCGTTACAACTGGAGAAAACACAGTTGCAGCATCAGTTGCAGATTTGCGACAAAGAGCG
TGCCGCGTTAGAGGTATGGGGAGATTTCGATCCTGCGTCGGTTATGCGGTTGCAAGAAGTTGGATATCAGGTGAATTTCT
ATATTTGCTCAGAGAAGAACTTTAACGAGGAATGGTTGGATACGTACTATGCTACGGAGGTTAACCGTATTGGTTCACGC
ATTTATTTCATTACCATAACCAAAGAAGGAACGTTGCCCGAATTGGAAGTGGAATCGGTCAAATTGCCGGTAATGTCCTT
GAGTAGGCTTGCTGCCAGATGTGAAGATTTGGAACAGCAAATGAAGAGTGTGGATGATAAGTTAGCTGCCATAGCAGGAG
AAAAACTTCTTTCTTTGCAAGTTGCACAAGCTAATATCCGCTCACAGATAGAATTCTCAAAAGTGGTGCTAAGTACTGAA
CAAGCTGCGGATGACAAATTGATGTTGTTACAGGGGTGGGCACCGGCTACGCAGATTCCGGAGATTACTAATTTTCTGAA
TCAACAGGAGGCGTACTTTGAAATTGCTGACCCTACGCCGGAGGACAATGTACCTATTCAGTTGAATAATAAAGGATTCT
TCCGTCTGTTTGAACCGATTATGAAACTGTATATGCTTCCTAAGTATAATGAACTGGATTTGACGCCGTTCTTTGCCCCT
TTCTTTATGCTCTTTTTCGGGCTGTGTTTGGGCGATTCGGGCTATGGTCTGTTCATGGTATTAGGAGTAACTGTTTATCG
TATGTTGGCGAAGAATGTCGGTGCTTCCATGAAGCCCATCTTAACTTTGGTGCAGATTTTGGGTGCTTCTACTTTCTTCT
GCGGTATGCTGACAGGTACTTTTTTCGGATTTAATCTGTATGGTAATGATATTCCGTTCTTTAATAAGATGCGTGATTTG
TTCTTCTTGGACAATCAATGGATGTTTAATCTTTCATTGATTTTGGGAGCGGTACAGATTATTTTCGGTATGATACTGAA
AGCGGCTAATCAGACCATTCAGTTCGGATTGAAATATGCATTGTCAACTATCGGATGGATTATTGTATTGGTAAGTACAG
CTTTGGCATTCCTATTGGGAGATACCATGCCGATGGGAGGAACTGTCCATTTGGTAATTCTGGGGCTTGCCGGTGTGCTG
ATTTTCTTGCTCAACAGTCCAGGAAAGAATATTTTTCTCAATATCGGTTTGGGTTTGTGGGATTCCTACAATATGGCAAC
CGGTTTGCTGGGGGATATCCTTTCGTATGTGCGTTTGTTTGCTTTAGGTCTGTCGGGTGGTATTCTTGCCAGCGTATTCA
ATAGTCTGGCGGCTGGAATGAGTCCTGATAATGCAATTGCAGGTCCGATAGTGATGGTATTGATTTTCTTGATAGGTCAT
TCTATCAACATGTTTATGAATATATTGGGAGCGATGGTTCATCCGATGCGTCTGACTTTCGTGGAGTTTTTTAAGAATTC
GGGTTACGAAGGAGGGGGTAAGGAGTACAAGCCTTTCAAGAATTGA

Upstream 100 bases:

>100_bases
TGCGAAAGATAAAACGATTTATGGAGGATGAAGAGAATTTGTCCAAATCATCGCAGAAGATTCTGAAATCTATTCAAGAG
AAAAGAAAGGAGGCGGAGGC

Downstream 100 bases:

>100_bases
AGAATGAGAATAAAGAATTAAAAGCTGTTTAAGCCTTTTCGGCATTGTCATTTTGAATAAATGTTGTATCCTTGTGCAGA
CAGAAAAGCTAGAAAGGGAG

Product: putative V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit I; V-type sodium pump subunit I [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MITKMKKLTFLIYHKDYECFLQNIRDLGVVHVAEKAQGTAENTELQESIRLSDHYASTIKFLQGFNVELQEQKGDTARGE
KALEEVEALQLEKTQLQHQLQICDKERAALEVWGDFDPASVMRLQEVGYQVNFYICSEKNFNEEWLDTYYATEVNRIGSR
IYFITITKEGTLPELEVESVKLPVMSLSRLAARCEDLEQQMKSVDDKLAAIAGEKLLSLQVAQANIRSQIEFSKVVLSTE
QAADDKLMLLQGWAPATQIPEITNFLNQQEAYFEIADPTPEDNVPIQLNNKGFFRLFEPIMKLYMLPKYNELDLTPFFAP
FFMLFFGLCLGDSGYGLFMVLGVTVYRMLAKNVGASMKPILTLVQILGASTFFCGMLTGTFFGFNLYGNDIPFFNKMRDL
FFLDNQWMFNLSLILGAVQIIFGMILKAANQTIQFGLKYALSTIGWIIVLVSTALAFLLGDTMPMGGTVHLVILGLAGVL
IFLLNSPGKNIFLNIGLGLWDSYNMATGLLGDILSYVRLFALGLSGGILASVFNSLAAGMSPDNAIAGPIVMVLIFLIGH
SINMFMNILGAMVHPMRLTFVEFFKNSGYEGGGKEYKPFKN

Sequences:

>Translated_601_residues
MITKMKKLTFLIYHKDYECFLQNIRDLGVVHVAEKAQGTAENTELQESIRLSDHYASTIKFLQGFNVELQEQKGDTARGE
KALEEVEALQLEKTQLQHQLQICDKERAALEVWGDFDPASVMRLQEVGYQVNFYICSEKNFNEEWLDTYYATEVNRIGSR
IYFITITKEGTLPELEVESVKLPVMSLSRLAARCEDLEQQMKSVDDKLAAIAGEKLLSLQVAQANIRSQIEFSKVVLSTE
QAADDKLMLLQGWAPATQIPEITNFLNQQEAYFEIADPTPEDNVPIQLNNKGFFRLFEPIMKLYMLPKYNELDLTPFFAP
FFMLFFGLCLGDSGYGLFMVLGVTVYRMLAKNVGASMKPILTLVQILGASTFFCGMLTGTFFGFNLYGNDIPFFNKMRDL
FFLDNQWMFNLSLILGAVQIIFGMILKAANQTIQFGLKYALSTIGWIIVLVSTALAFLLGDTMPMGGTVHLVILGLAGVL
IFLLNSPGKNIFLNIGLGLWDSYNMATGLLGDILSYVRLFALGLSGGILASVFNSLAAGMSPDNAIAGPIVMVLIFLIGH
SINMFMNILGAMVHPMRLTFVEFFKNSGYEGGGKEYKPFKN
>Mature_601_residues
MITKMKKLTFLIYHKDYECFLQNIRDLGVVHVAEKAQGTAENTELQESIRLSDHYASTIKFLQGFNVELQEQKGDTARGE
KALEEVEALQLEKTQLQHQLQICDKERAALEVWGDFDPASVMRLQEVGYQVNFYICSEKNFNEEWLDTYYATEVNRIGSR
IYFITITKEGTLPELEVESVKLPVMSLSRLAARCEDLEQQMKSVDDKLAAIAGEKLLSLQVAQANIRSQIEFSKVVLSTE
QAADDKLMLLQGWAPATQIPEITNFLNQQEAYFEIADPTPEDNVPIQLNNKGFFRLFEPIMKLYMLPKYNELDLTPFFAP
FFMLFFGLCLGDSGYGLFMVLGVTVYRMLAKNVGASMKPILTLVQILGASTFFCGMLTGTFFGFNLYGNDIPFFNKMRDL
FFLDNQWMFNLSLILGAVQIIFGMILKAANQTIQFGLKYALSTIGWIIVLVSTALAFLLGDTMPMGGTVHLVILGLAGVL
IFLLNSPGKNIFLNIGLGLWDSYNMATGLLGDILSYVRLFALGLSGGILASVFNSLAAGMSPDNAIAGPIVMVLIFLIGH
SINMFMNILGAMVHPMRLTFVEFFKNSGYEGGGKEYKPFKN

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 67262; Mature: 67262

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITKMKKLTFLIYHKDYECFLQNIRDLGVVHVAEKAQGTAENTELQESIRLSDHYASTIK
CCCCHHHEEEEEEECCHHHHHHHHHHCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLQGFNVELQEQKGDTARGEKALEEVEALQLEKTQLQHQLQICDKERAALEVWGDFDPAS
HHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHH
VMRLQEVGYQVNFYICSEKNFNEEWLDTYYATEVNRIGSRIYFITITKEGTLPELEVESV
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHE
KLPVMSLSRLAARCEDLEQQMKSVDDKLAAIAGEKLLSLQVAQANIRSQIEFSKVVLSTE
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAADDKLMLLQGWAPATQIPEITNFLNQQEAYFEIADPTPEDNVPIQLNNKGFFRLFEPI
HCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCHHHHHHHH
MKLYMLPKYNELDLTPFFAPFFMLFFGLCLGDSGYGLFMVLGVTVYRMLAKNVGASMKPI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
LTLVQILGASTFFCGMLTGTFFGFNLYGNDIPFFNKMRDLFFLDNQWMFNLSLILGAVQI
HHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHH
IFGMILKAANQTIQFGLKYALSTIGWIIVLVSTALAFLLGDTMPMGGTVHLVILGLAGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IFLLNSPGKNIFLNIGLGLWDSYNMATGLLGDILSYVRLFALGLSGGILASVFNSLAAGM
HHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SPDNAIAGPIVMVLIFLIGHSINMFMNILGAMVHPMRLTFVEFFKNSGYEGGGKEYKPFK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
N
C
>Mature Secondary Structure
MITKMKKLTFLIYHKDYECFLQNIRDLGVVHVAEKAQGTAENTELQESIRLSDHYASTIK
CCCCHHHEEEEEEECCHHHHHHHHHHCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLQGFNVELQEQKGDTARGEKALEEVEALQLEKTQLQHQLQICDKERAALEVWGDFDPAS
HHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHH
VMRLQEVGYQVNFYICSEKNFNEEWLDTYYATEVNRIGSRIYFITITKEGTLPELEVESV
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHE
KLPVMSLSRLAARCEDLEQQMKSVDDKLAAIAGEKLLSLQVAQANIRSQIEFSKVVLSTE
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAADDKLMLLQGWAPATQIPEITNFLNQQEAYFEIADPTPEDNVPIQLNNKGFFRLFEPI
HCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCHHHHHHHH
MKLYMLPKYNELDLTPFFAPFFMLFFGLCLGDSGYGLFMVLGVTVYRMLAKNVGASMKPI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
LTLVQILGASTFFCGMLTGTFFGFNLYGNDIPFFNKMRDLFFLDNQWMFNLSLILGAVQI
HHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHH
IFGMILKAANQTIQFGLKYALSTIGWIIVLVSTALAFLLGDTMPMGGTVHLVILGLAGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IFLLNSPGKNIFLNIGLGLWDSYNMATGLLGDILSYVRLFALGLSGGILASVFNSLAAGM
HHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SPDNAIAGPIVMVLIFLIGHSINMFMNILGAMVHPMRLTFVEFFKNSGYEGGGKEYKPFK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8157629; 8144530 [H]