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The map label for this gene is gpo [H]

Identifier: 150005962

GI number: 150005962

Start: 4305566

End: 4306105

Strand: Reverse

Name: gpo [H]

Synonym: BVU_3460

Alternate gene names: 150005962

Gene position: 4306105-4305566 (Counterclockwise)

Preceding gene: 150005968

Following gene: 150005959

Centisome position: 83.4

GC content: 39.44

Gene sequence:

>540_bases
ATGAAAACATTTATATTAAGCATAATTGTAACCATGATTACATCGGTAGCTGGTGCACAGCAAAAAAGTTTTTATGACTT
TACGGTCAAGACTATTGACGGGAAGGACTTGCCACTTTCCACGTTCAAGGGTAAGAAAGTATTGGTAGTCAATGTGGCAT
CTAAATGCGGTTTCACTCCCCAATACGCCAAGTTGGAGGAGTTGTATGAGAAATATGGAAAAGATGATTTTGTCGTTATC
GGATTTCCTGCCAATAATTTCCTGCATCAGGAACCCGGAACGAATGAAGAAATCAAGGAGTTTTGTACGTTGAATTATGG
AGTGACTTTTCCTATGATGGCTAAAATATCTGTAAAGGGGAAAGATATAGCTCCCCTTTATCAATGGCTTACGCATAAAA
GTGAAAACGGGGTTTCGGATGCTAAGATAGGGTGGAACTTTCATAAGTTTCTGATTGATGAAAATGGTAGATGGGTTGCC
TCAATCGGCTCTACTACCAGTCCGCTTTCACAGGAAATTGTAGGATGGATTGAAGAATAA

Upstream 100 bases:

>100_bases
GTAACATGGAGGAAGCTGTCCGATAGGTATCCGCCAATCTTTTCTTTCAGAGAAAACTTTTCAATTTCATGAATTGTTCT
ATTATAAAATAGCATTTCAA

Downstream 100 bases:

>100_bases
AATGACCAGAAGATAAATAATGCCCTATTGTTATTGCACCAGCTTTCCGTTTTTCAGTTCCGACATCAGCAGGTCATAGA
CGTATGCCGGGCTTTCGATA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKTFILSIIVTMITSVAGAQQKSFYDFTVKTIDGKDLPLSTFKGKKVLVVNVASKCGFTPQYAKLEELYEKYGKDDFVVI
GFPANNFLHQEPGTNEEIKEFCTLNYGVTFPMMAKISVKGKDIAPLYQWLTHKSENGVSDAKIGWNFHKFLIDENGRWVA
SIGSTTSPLSQEIVGWIEE

Sequences:

>Translated_179_residues
MKTFILSIIVTMITSVAGAQQKSFYDFTVKTIDGKDLPLSTFKGKKVLVVNVASKCGFTPQYAKLEELYEKYGKDDFVVI
GFPANNFLHQEPGTNEEIKEFCTLNYGVTFPMMAKISVKGKDIAPLYQWLTHKSENGVSDAKIGWNFHKFLIDENGRWVA
SIGSTTSPLSQEIVGWIEE
>Mature_179_residues
MKTFILSIIVTMITSVAGAQQKSFYDFTVKTIDGKDLPLSTFKGKKVLVVNVASKCGFTPQYAKLEELYEKYGKDDFVVI
GFPANNFLHQEPGTNEEIKEFCTLNYGVTFPMMAKISVKGKDIAPLYQWLTHKSENGVSDAKIGWNFHKFLIDENGRWVA
SIGSTTSPLSQEIVGWIEE

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=153, Percent_Identity=41.1764705882353, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI90903240, Length=150, Percent_Identity=41.3333333333333, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI15618997, Length=149, Percent_Identity=40.2684563758389, Blast_Score=113, Evalue=7e-26,
Organism=Homo sapiens, GI192455698, Length=162, Percent_Identity=36.4197530864198, Blast_Score=103, Evalue=5e-23,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=40.4580152671756, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI32967607, Length=159, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI6006001, Length=188, Percent_Identity=32.4468085106383, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI4557629, Length=186, Percent_Identity=29.5698924731183, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI41406084, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI33186887, Length=155, Percent_Identity=31.6129032258064, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=40.7185628742515, Blast_Score=131, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17506887, Length=151, Percent_Identity=39.7350993377483, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17535473, Length=147, Percent_Identity=38.7755102040816, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71993584, Length=155, Percent_Identity=39.3548387096774, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17550320, Length=157, Percent_Identity=33.1210191082803, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=34.7560975609756, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193209493, Length=157, Percent_Identity=32.484076433121, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71999642, Length=77, Percent_Identity=40.2597402597403, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=98, Percent_Identity=37.7551020408163, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=153, Percent_Identity=52.2875816993464, Blast_Score=163, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322228, Length=158, Percent_Identity=48.1012658227848, Blast_Score=155, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=43.3962264150943, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656772, Length=153, Percent_Identity=42.483660130719, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24656767, Length=153, Percent_Identity=42.483660130719, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24656777, Length=154, Percent_Identity=42.2077922077922, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI85726443, Length=150, Percent_Identity=34, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20073; Mature: 20073

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFILSIIVTMITSVAGAQQKSFYDFTVKTIDGKDLPLSTFKGKKVLVVNVASKCGFTP
CHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCC
QYAKLEELYEKYGKDDFVVIGFPANNFLHQEPGTNEEIKEFCTLNYGVTFPMMAKISVKG
CHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECC
KDIAPLYQWLTHKSENGVSDAKIGWNFHKFLIDENGRWVASIGSTTSPLSQEIVGWIEE
CCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTFILSIIVTMITSVAGAQQKSFYDFTVKTIDGKDLPLSTFKGKKVLVVNVASKCGFTP
CHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCC
QYAKLEELYEKYGKDDFVVIGFPANNFLHQEPGTNEEIKEFCTLNYGVTFPMMAKISVKG
CHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECC
KDIAPLYQWLTHKSENGVSDAKIGWNFHKFLIDENGRWVASIGSTTSPLSQEIVGWIEE
CCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]