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The map label for this gene is kdsB

Identifier: 150005832

GI number: 150005832

Start: 4163980

End: 4164738

Strand: Reverse

Name: kdsB

Synonym: BVU_3328

Alternate gene names: 150005832

Gene position: 4164738-4163980 (Counterclockwise)

Preceding gene: 150005839

Following gene: 150005831

Centisome position: 80.66

GC content: 44.93

Gene sequence:

>759_bases
ATGAAATTTATTGGAATTATTCCTGCAAGATATGCCTCTACACGTTTTCCTGCCAAACCTCTGGCCGTCTTGGGAGGCAA
GCCTGTGATTCAGAGAGTCTATGAACAAGTGTCCGGCATATTGGATGAAGCATATGTAGCGACGGACGATGAACGCATTG
AATCCGCTGTAAAAGCTTTTGGCGGAAAAGTGGTCATGACCTCCGTTCACCATAAAAGCGGCACAGACCGTTGCTATGAA
GCGTATACCAAAGTAGGACGAGGATATGATGTGGTTGTAAATATCCAGGGTGATGAACCTTTTATTCAAAAATCACAGCT
TGAAGCCGTGAAAGCTTGCTTTGAAGATCCTGCCACACAGATTGCGACTTTAGTGAAACCTTTCATCCCGGATGACGGGC
TTGAAGCCTTGGAAAATGTAAACTCTCCCAAAGTAGTAGTCGGTAAGAATATGAATGCTTTGTATTTCAGCCGTTCCATC
ATTCCTTTCCAGCGTAATGTGGAGAAGGAAGGCTGGCTGAAAGGGCATACTTACTATAAACATATCGGTCTGTATGCTTA
TCGGGCCGATGTACTGAAAGAAATAACTTCGCTTCCACAATCTTCGCTGGAGCTGGCTGAATCGTTGGAGCAGCTTCGTT
GGCTGGAAAATGGTTATACTATTAAGGTGGGAATCAGTGAAGTGGAGACAATAGGCATTGATACGCCTCAGGATCTGGCA
CGTGCCGAAGCATTTTTAAAACAAAGGGAGGGGGAGTAA

Upstream 100 bases:

>100_bases
GCAAACAATGGTGTTCGTCCATAACATTTATTGCATTAATGGTGCAAATGTATGAAATGTTTTTGTTACTTTTGCATGAA
TATATAAAAGAAATGCTACC

Downstream 100 bases:

>100_bases
ATGCTGGACAGAACCACCCCACCGCCAATCCGCCAACTAAGCGAATTCAGTATAACCCGTCCCGACAGGAGGACGATGAA
GAACGGGATGCCTTTGAATA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKFIGIIPARYASTRFPAKPLAVLGGKPVIQRVYEQVSGILDEAYVATDDERIESAVKAFGGKVVMTSVHHKSGTDRCYE
AYTKVGRGYDVVVNIQGDEPFIQKSQLEAVKACFEDPATQIATLVKPFIPDDGLEALENVNSPKVVVGKNMNALYFSRSI
IPFQRNVEKEGWLKGHTYYKHIGLYAYRADVLKEITSLPQSSLELAESLEQLRWLENGYTIKVGISEVETIGIDTPQDLA
RAEAFLKQREGE

Sequences:

>Translated_252_residues
MKFIGIIPARYASTRFPAKPLAVLGGKPVIQRVYEQVSGILDEAYVATDDERIESAVKAFGGKVVMTSVHHKSGTDRCYE
AYTKVGRGYDVVVNIQGDEPFIQKSQLEAVKACFEDPATQIATLVKPFIPDDGLEALENVNSPKVVVGKNMNALYFSRSI
IPFQRNVEKEGWLKGHTYYKHIGLYAYRADVLKEITSLPQSSLELAESLEQLRWLENGYTIKVGISEVETIGIDTPQDLA
RAEAFLKQREGE
>Mature_252_residues
MKFIGIIPARYASTRFPAKPLAVLGGKPVIQRVYEQVSGILDEAYVATDDERIESAVKAFGGKVVMTSVHHKSGTDRCYE
AYTKVGRGYDVVVNIQGDEPFIQKSQLEAVKACFEDPATQIATLVKPFIPDDGLEALENVNSPKVVVGKNMNALYFSRSI
IPFQRNVEKEGWLKGHTYYKHIGLYAYRADVLKEITSLPQSSLELAESLEQLRWLENGYTIKVGISEVETIGIDTPQDLA
RAEAFLKQREGE

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=252, Percent_Identity=42.0634920634921, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_BACV8 (A6L5J0)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001300576.1
- ProteinModelPortal:   A6L5J0
- SMR:   A6L5J0
- STRING:   A6L5J0
- GeneID:   5304289
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_3328
- NMPDR:   fig|435590.6.peg.3102
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   NTRQDAL
- ProtClustDB:   PRK05450
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 28074; Mature: 28074

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIGIIPARYASTRFPAKPLAVLGGKPVIQRVYEQVSGILDEAYVATDDERIESAVKAF
CCEEECCCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GGKVVMTSVHHKSGTDRCYEAYTKVGRGYDVVVNIQGDEPFIQKSQLEAVKACFEDPATQ
CCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHH
IATLVKPFIPDDGLEALENVNSPKVVVGKNMNALYFSRSIIPFQRNVEKEGWLKGHTYYK
HHHHHHHCCCCCHHHHHHCCCCCEEEECCCCCEEEEECCCCCHHHCCCCCCCCCCCHHHH
HIGLYAYRADVLKEITSLPQSSLELAESLEQLRWLENGYTIKVGISEVETIGIDTPQDLA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHEECCCCHHHHH
RAEAFLKQREGE
HHHHHHHHHCCC
>Mature Secondary Structure
MKFIGIIPARYASTRFPAKPLAVLGGKPVIQRVYEQVSGILDEAYVATDDERIESAVKAF
CCEEECCCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GGKVVMTSVHHKSGTDRCYEAYTKVGRGYDVVVNIQGDEPFIQKSQLEAVKACFEDPATQ
CCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHH
IATLVKPFIPDDGLEALENVNSPKVVVGKNMNALYFSRSIIPFQRNVEKEGWLKGHTYYK
HHHHHHHCCCCCHHHHHHCCCCCEEEECCCCCEEEEECCCCCHHHCCCCCCCCCCCHHHH
HIGLYAYRADVLKEITSLPQSSLELAESLEQLRWLENGYTIKVGISEVETIGIDTPQDLA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHEECCCCHHHHH
RAEAFLKQREGE
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA