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The map label for this gene is kdpD [H]

Identifier: 150005759

GI number: 150005759

Start: 4081640

End: 4082767

Strand: Reverse

Name: kdpD [H]

Synonym: BVU_3252

Alternate gene names: 150005759

Gene position: 4082767-4081640 (Counterclockwise)

Preceding gene: 150005760

Following gene: 150005758

Centisome position: 79.07

GC content: 41.05

Gene sequence:

>1128_bases
ATGGAAGACAGAGAAGAAAGTGTACAGCATTTTTTAGATTTGATTAAACGTTCACGGCGTGGAAAGTTTAAAATCTATAT
CGGAATGATAGCCGGTGTAGGGAAAAGTTATCGTATGCTGCAAGAAGCTCACGAAATGTTGGAGAACGGTGTAGATGTAC
AGATAGGTTATATTGAAACGCACGGACGTGCAGGAACCGTTGCTATGTTGGAAGGATTGCCTGTTATCTCTCGGAAAAAG
ATATTTTACAAAGGTAAGGAAGTGGAAGAAATGGATCTTGATGCCATTCTTCAGTTACATCCCGAACTGGTTATAGTAGA
TGAATTGGCACATACCAACATCGAGGGCAGCCGGAATGAGAAACGTTGGCAAGATGTAATGGAATTGTTGGATGCCGGTA
TAAACGTAATTTCTGCAGTTAATATCCAGCATATAGAAAGTTTGAATGAAGACGTAAAAGGCATAGCAGGTATAGAGGTT
AAGGAACGGATTCCGGACAAGGTGTTGCAGGATGCGGATGAAGTGGTAAATATAGACCTTACTGCCGAAGAACTGATAAA
CCGGTTGAAAGCCGGGAAAATCTATCGCCCTGAAAAGATTCAATTGGCACTGAATAACTTTTTTAAGACAGAGAATATTC
TTCAGTTACGTGAACTGGCACTAAAAGAAGTGGCCTTTCGAGTCGAGAAAAAAGTTGAAAATGAAATTGTTACAGGCGAA
AAGGGTATCCGGCACGAGAAGTTTTTGGCATGTATCAGCAGTAATGAACGGACTCCCCGACATATCATCCGTAAAGCGGC
ACGGCTTGCTTCCCGGTACAATACGGTCTTTTTTGCCCTTTATGTACAAACGCCTGCCGAAAGTACGGAACGTATTCCAT
TGGCAACACAGCGGCATTTACTTAATCATTTTAAACTGGTTACCGAGTTGGGCGGTGAAGTTATCCAAGTTTCATCTTCC
GATATTATGGGAGAAATAATTAAGACTTGTCGTCAACGTGGAATTACAACTGTCTGTATGGGGCATCCTGCTTTCAAAAT
GCCCGGTGCATTATTCAGTCTTTCCAAATATCGAAAATTTCTACACTCTTTAGCAGAAATGGACATAGATTTGATTATAC
TTGCATAA

Upstream 100 bases:

>100_bases
CTAAGCCGTTTGTTTTATTGGTATATTCTTTGCCTGTTATAAAAGGACTGATATTAAATATGCGGAAAATTGTTATATTG
CCAATATGATAAAGTAACAA

Downstream 100 bases:

>100_bases
AAAATAAAAGTTATGAATATAAAGTCGAAACTAACCCTCGCCATAGGGATATTGGTGGCAATGATTGTACTGTTGGTTGT
ACTTTCTGTTGTGAATTTGC

Product: osmosensitive K+ channel histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MEDREESVQHFLDLIKRSRRGKFKIYIGMIAGVGKSYRMLQEAHEMLENGVDVQIGYIETHGRAGTVAMLEGLPVISRKK
IFYKGKEVEEMDLDAILQLHPELVIVDELAHTNIEGSRNEKRWQDVMELLDAGINVISAVNIQHIESLNEDVKGIAGIEV
KERIPDKVLQDADEVVNIDLTAEELINRLKAGKIYRPEKIQLALNNFFKTENILQLRELALKEVAFRVEKKVENEIVTGE
KGIRHEKFLACISSNERTPRHIIRKAARLASRYNTVFFALYVQTPAESTERIPLATQRHLLNHFKLVTELGGEVIQVSSS
DIMGEIIKTCRQRGITTVCMGHPAFKMPGALFSLSKYRKFLHSLAEMDIDLIILA

Sequences:

>Translated_375_residues
MEDREESVQHFLDLIKRSRRGKFKIYIGMIAGVGKSYRMLQEAHEMLENGVDVQIGYIETHGRAGTVAMLEGLPVISRKK
IFYKGKEVEEMDLDAILQLHPELVIVDELAHTNIEGSRNEKRWQDVMELLDAGINVISAVNIQHIESLNEDVKGIAGIEV
KERIPDKVLQDADEVVNIDLTAEELINRLKAGKIYRPEKIQLALNNFFKTENILQLRELALKEVAFRVEKKVENEIVTGE
KGIRHEKFLACISSNERTPRHIIRKAARLASRYNTVFFALYVQTPAESTERIPLATQRHLLNHFKLVTELGGEVIQVSSS
DIMGEIIKTCRQRGITTVCMGHPAFKMPGALFSLSKYRKFLHSLAEMDIDLIILA
>Mature_375_residues
MEDREESVQHFLDLIKRSRRGKFKIYIGMIAGVGKSYRMLQEAHEMLENGVDVQIGYIETHGRAGTVAMLEGLPVISRKK
IFYKGKEVEEMDLDAILQLHPELVIVDELAHTNIEGSRNEKRWQDVMELLDAGINVISAVNIQHIESLNEDVKGIAGIEV
KERIPDKVLQDADEVVNIDLTAEELINRLKAGKIYRPEKIQLALNNFFKTENILQLRELALKEVAFRVEKKVENEIVTGE
KGIRHEKFLACISSNERTPRHIIRKAARLASRYNTVFFALYVQTPAESTERIPLATQRHLLNHFKLVTELGGEVIQVSSS
DIMGEIIKTCRQRGITTVCMGHPAFKMPGALFSLSKYRKFLHSLAEMDIDLIILA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=361, Percent_Identity=40.4432132963989, Blast_Score=277, Evalue=8e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42636; Mature: 42636

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDREESVQHFLDLIKRSRRGKFKIYIGMIAGVGKSYRMLQEAHEMLENGVDVQIGYIET
CCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEE
HGRAGTVAMLEGLPVISRKKIFYKGKEVEEMDLDAILQLHPELVIVDELAHTNIEGSRNE
CCCCCCCHHHCCCCCHHCCHHEECCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCH
KRWQDVMELLDAGINVISAVNIQHIESLNEDVKGIAGIEVKERIPDKVLQDADEVVNIDL
HHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHCHHHHHHCHHHHEEECC
TAEELINRLKAGKIYRPEKIQLALNNFFKTENILQLRELALKEVAFRVEKKVENEIVTGE
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KGIRHEKFLACISSNERTPRHIIRKAARLASRYNTVFFALYVQTPAESTERIPLATQRHL
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCHHHHHHH
LNHFKLVTELGGEVIQVSSSDIMGEIIKTCRQRGITTVCMGHPAFKMPGALFSLSKYRKF
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHCCHHHHHHHHHHHH
LHSLAEMDIDLIILA
HHHHHHCCEEEEEEC
>Mature Secondary Structure
MEDREESVQHFLDLIKRSRRGKFKIYIGMIAGVGKSYRMLQEAHEMLENGVDVQIGYIET
CCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEE
HGRAGTVAMLEGLPVISRKKIFYKGKEVEEMDLDAILQLHPELVIVDELAHTNIEGSRNE
CCCCCCCHHHCCCCCHHCCHHEECCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCH
KRWQDVMELLDAGINVISAVNIQHIESLNEDVKGIAGIEVKERIPDKVLQDADEVVNIDL
HHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHCHHHHHHCHHHHEEECC
TAEELINRLKAGKIYRPEKIQLALNNFFKTENILQLRELALKEVAFRVEKKVENEIVTGE
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KGIRHEKFLACISSNERTPRHIIRKAARLASRYNTVFFALYVQTPAESTERIPLATQRHL
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCHHHHHHH
LNHFKLVTELGGEVIQVSSSDIMGEIIKTCRQRGITTVCMGHPAFKMPGALFSLSKYRKF
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHCCHHHHHHHHHHHH
LHSLAEMDIDLIILA
HHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]