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The map label for this gene is cobT

Identifier: 150005660

GI number: 150005660

Start: 3968614

End: 3969651

Strand: Reverse

Name: cobT

Synonym: BVU_3150

Alternate gene names: 150005660

Gene position: 3969651-3968614 (Counterclockwise)

Preceding gene: 150005661

Following gene: 150005659

Centisome position: 76.88

GC content: 44.03

Gene sequence:

>1038_bases
ATGAAAAACTTTCATATTGAGTATCCCGATGAAGGTCTTCGGGAGGCATTGATAGACAAAATCAACAATTTGACAAAGCC
CAAAGGTTCATTGGGCGTTCTGGAAGACCTTGCATTGCAAATCGGATTAATCCAACAAACCCTCTCCCCTACATTAAGCC
ATCCGCACAACGTACTTTTTGCAGCCGATCATGGTATAGTAGAAGAAGGGGTAAGCAAGTCTCCCAAAGAAATCACTTGG
CAACAACTAAGTAATTTTTTACATGGAGGTGCCGGAGTTAATTTTTTATGCCGCCAACATGGTTTTAAGCTTGTATTAGT
AGACTCAGGAGTCGATTACGATCTTCCTTACGAGAAAGGCATTATCAACTGTAGCGTAGGACGTGGCACGCACAGTTTTC
TAAAAGGTCCTGCAATGAGTATGGAAGAAATGGAATTATGCCTGGAACGTGGAGCAAAGATAACGGATATGATTCATGCT
GACGGCTGCAATGTGGTCAGTTTTGGCGAAATGGGTATTGGCAACACCTCCCCTTCCTCTGTCTGGATGCATTTGCTGAC
AGGTATTTCATTAGAGCAATGTGTAGGTGCGGGAAGCGGACTGGATTCAGAAGGCATCCGCCATAAATACAATGTATTGA
AACAATCGGTTGACCATTATGCCGGTGACGGTTCTGCAAAAGATATCATCGCCTGGTTCGGAGGATATGAAATGGTTATG
GCAATAGGCGGCATGCTCCGGGCGGCAGAATTAAGAATGATTATTCTGGTAGACGGCTTCATCATGACCAACTGCATACT
GGCCGCCTCAAAACTTCATCCGGAAGTTTTGTCGTATGCCATATTCGGACATCAGGGAGATGAAACCGGTCATAAACTAG
TATTGGACGCCATGAAAGTACGCCCTTTATTAAATTTAGGTCTGCGCTTGGGAGAAGGAACAGGAGCGATATGCGCTTAT
CCCATCGTTGTTTCCTCTGTAAACATGATGAATGAGATGGACAATTTCGCCCATGCCTCCATCACTAAATATTTTTAA

Upstream 100 bases:

>100_bases
CAGATTTACAGGGCTGGATGAATCAATATATAGCTTCAAAAGCAGACCAAGTATATTTGATGGTATCGGGAATTCCTGTT
CCTATAAAATAATAAATACA

Downstream 100 bases:

>100_bases
CCATGAAACTGCTTGCCTCCCTCATTTTTTTCACACGCCTTCCGTTTTGGAAAATAGCTGACGTACCACCTGTTTACTTT
AAACGAGTAGTGGACTACTG

Product: putative phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKNFHIEYPDEGLREALIDKINNLTKPKGSLGVLEDLALQIGLIQQTLSPTLSHPHNVLFAADHGIVEEGVSKSPKEITW
QQLSNFLHGGAGVNFLCRQHGFKLVLVDSGVDYDLPYEKGIINCSVGRGTHSFLKGPAMSMEEMELCLERGAKITDMIHA
DGCNVVSFGEMGIGNTSPSSVWMHLLTGISLEQCVGAGSGLDSEGIRHKYNVLKQSVDHYAGDGSAKDIIAWFGGYEMVM
AIGGMLRAAELRMIILVDGFIMTNCILAASKLHPEVLSYAIFGHQGDETGHKLVLDAMKVRPLLNLGLRLGEGTGAICAY
PIVVSSVNMMNEMDNFAHASITKYF

Sequences:

>Translated_345_residues
MKNFHIEYPDEGLREALIDKINNLTKPKGSLGVLEDLALQIGLIQQTLSPTLSHPHNVLFAADHGIVEEGVSKSPKEITW
QQLSNFLHGGAGVNFLCRQHGFKLVLVDSGVDYDLPYEKGIINCSVGRGTHSFLKGPAMSMEEMELCLERGAKITDMIHA
DGCNVVSFGEMGIGNTSPSSVWMHLLTGISLEQCVGAGSGLDSEGIRHKYNVLKQSVDHYAGDGSAKDIIAWFGGYEMVM
AIGGMLRAAELRMIILVDGFIMTNCILAASKLHPEVLSYAIFGHQGDETGHKLVLDAMKVRPLLNLGLRLGEGTGAICAY
PIVVSSVNMMNEMDNFAHASITKYF
>Mature_345_residues
MKNFHIEYPDEGLREALIDKINNLTKPKGSLGVLEDLALQIGLIQQTLSPTLSHPHNVLFAADHGIVEEGVSKSPKEITW
QQLSNFLHGGAGVNFLCRQHGFKLVLVDSGVDYDLPYEKGIINCSVGRGTHSFLKGPAMSMEEMELCLERGAKITDMIHA
DGCNVVSFGEMGIGNTSPSSVWMHLLTGISLEQCVGAGSGLDSEGIRHKYNVLKQSVDHYAGDGSAKDIIAWFGGYEMVM
AIGGMLRAAELRMIILVDGFIMTNCILAASKLHPEVLSYAIFGHQGDETGHKLVLDAMKVRPLLNLGLRLGEGTGAICAY
PIVVSSVNMMNEMDNFAHASITKYF

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=323, Percent_Identity=34.0557275541796, Blast_Score=181, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_BACV8 (A6L518)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001300404.1
- ProteinModelPortal:   A6L518
- SMR:   A6L518
- STRING:   A6L518
- GeneID:   5304111
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_3150
- NMPDR:   fig|435590.6.peg.2942
- eggNOG:   COG2038
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   CLSK826801
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 37448; Mature: 37448

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: ACT_SITE 312-312

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFHIEYPDEGLREALIDKINNLTKPKGSLGVLEDLALQIGLIQQTLSPTLSHPHNVLF
CCCCEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
AADHGIVEEGVSKSPKEITWQQLSNFLHGGAGVNFLCRQHGFKLVLVDSGVDYDLPYEKG
EECCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCC
IINCSVGRGTHSFLKGPAMSMEEMELCLERGAKITDMIHADGCNVVSFGEMGIGNTSPSS
EEEEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEHHCCCCCCEEEECCCCCCCCCHHH
VWMHLLTGISLEQCVGAGSGLDSEGIRHKYNVLKQSVDHYAGDGSAKDIIAWFGGYEMVM
HHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHH
AIGGMLRAAELRMIILVDGFIMTNCILAASKLHPEVLSYAIFGHQGDETGHKLVLDAMKV
HHHHHHHHHHEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
RPLLNLGLRLGEGTGAICAYPIVVSSVNMMNEMDNFAHASITKYF
HHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNFHIEYPDEGLREALIDKINNLTKPKGSLGVLEDLALQIGLIQQTLSPTLSHPHNVLF
CCCCEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
AADHGIVEEGVSKSPKEITWQQLSNFLHGGAGVNFLCRQHGFKLVLVDSGVDYDLPYEKG
EECCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCC
IINCSVGRGTHSFLKGPAMSMEEMELCLERGAKITDMIHADGCNVVSFGEMGIGNTSPSS
EEEEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEHHCCCCCCEEEECCCCCCCCCHHH
VWMHLLTGISLEQCVGAGSGLDSEGIRHKYNVLKQSVDHYAGDGSAKDIIAWFGGYEMVM
HHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHH
AIGGMLRAAELRMIILVDGFIMTNCILAASKLHPEVLSYAIFGHQGDETGHKLVLDAMKV
HHHHHHHHHHEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
RPLLNLGLRLGEGTGAICAYPIVVSSVNMMNEMDNFAHASITKYF
HHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA