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The map label for this gene is cirA [H]

Identifier: 150005604

GI number: 150005604

Start: 3909044

End: 3911221

Strand: Reverse

Name: cirA [H]

Synonym: BVU_3092

Alternate gene names: 150005604

Gene position: 3911221-3909044 (Counterclockwise)

Preceding gene: 150005609

Following gene: 150005603

Centisome position: 75.75

GC content: 44.26

Gene sequence:

>2178_bases
ATGAAAAAGAAATGTTTACTGACAGCCTTATTCGGCTGCATGGTGGTGTGTGCGTCCGCCCAGATATCGTTAAGTGGAAA
AGTAGTGGATGCCCGTACAGGAAAGCCGGTGGAAGGCGCTAACGTACGTTTGGAACAAACTACAATAGGATGTGCTACCA
ATCCTAAAGGAGAATTTTTGTTGAAAGACATCAAAGAGGGAACGTATACCCTGCGTACCAGTTGCCTGAATTATGCTCCT
GTCACTCAGAAAGTCAGTCAAAGTCAAAAAGAAATGGTGATAAGGCTGAAAAGTACCACTTTCAACATGGATCAGGTAGT
GGTAACCGGAACCGGAACTCACCACAAGCTGAAAGACAGCCCTGTACCCGTAGAGGTCATTTCCCAACGTGATCTGCAAA
ATGCCAATCCATCCAGTTTCCAGGATGCCTTGGTGAAACTGGTTCCCTCTATCTCGGTGCAAACCACCGCTATGGGAACA
ACCCTATACGTAAACGGACTGCCTGATAAATACCTCCTCGTATTAATTAACGGTAAAAAAGTAGCCGGAGATATTTCGGG
ATCTATAGATTACGACCGGATCAATATGGATGCCGTAAAACGTATTGAAGTATTAAAAGGAGCATCTTCCGCCCTTTATG
GCAGTGACGCCATCGCAGGAGTAATCAATATCATTACCGATGATCCTAAATCTGCATTGAATGTATCTTCCAATACCCGT
GTAAGTTCTCACGGACGAATTTCAGAATCAGTCAACGCAGACGCCAATGATGGAAAATTATCCGCACACTTGAACTATAA
TTACCGCACTTCGGATGGATGGCAACTGAATCCGTATGAGGAAAGCAAGGGAGAACTGGTGGAAACCACAAAGAAACCGG
TCTATAAGAATCATTCGCATAATGTGAGCCAAACCTTGAGCTACGCAGCCACAGAGCGTTTAAGCCTTCATTTGAACGGT
AATCTTTTTATCAGCGAGAACGACCGTACCGGAGCCTACGATTACAACAACCGGCATCAGTCCTATACAGTGGGTGGAAC
AGCCAAATATCTGTTGGCTAAGCGGGCTTCATATATAGAAGGGAATATAAGCACCACCAATTTCCGTTCTTTTTATGACT
ATATAAATGATGCAAAAACGCATAAAACCGGTGACGAAGTCCTCAGTAAAGACCAGACTTACACCAATGCCAATCTAAAA
GGTGTATTCAAAACCCACAAGAACAATACACTTTTTACCGGACTGGACTATGTATTCGAAGGCTTGGAGCCGACTGAAAC
CAGCAAGATGCTGAATAATGAATACCAAAGTGTTTATACACTGGCAGCATACGTACAGGACGAAGTAAAACTACTGGATG
CAATCAGCGTAGTGGCAGGTATACGGTATGCCTATAATGAAAAGTTTAAAAGCCAGTTCACGCCCAAACTATCCTTGATG
TACCAATATTCAGAACTGAATGTACGTGCATCCTACGCTGCCGGATTCCGTTCACCTACCTTGCAACAAATGTATGCCGT
TTCTGAAAGCCGTGGACAAATCACGGTCGGAGACCCTGGCCTGGACCCGGAAAAGAGCAATTTCTATAATTTGAATATAG
AATACAATCATCGTTTGTTCTCCATTGCCGCGTCCATTTATCAGAATGACCTGAAAGACAAGATTGAAGCGGAAGATATA
GGAACAACGCCCGAAGATATTGAAAACGGCATCACTCGCAGACGCCAGTACCGCAATATAGAAAAGGCACGTGTGAAAGG
CTTTGACATAGGTTTTTCAGTCCGTCCCTTCACAGGCTTCATGTTCGGAGCAAACTATATTTACACGGACGGGCGCAACC
GTACGGAAGACATCCGTTTGGAAAGAACAGTACGTCACTCGGGTAATTTCAATGCCAGCTGGCGAAAAACATGGAATGAT
TATACATTCAATATTGCAATCAACGGACGCTATCAAGGTACACGCTGGTCTAAAACTTACGGCAACGCCCCCGCCCACCA
GCTTTGGGATATCAACACACGCCATTCATTCAATTTAAAATCTGTTGCTCTGGAACCCGCCGTCGGAGTTGAAAACATTT
TCAATTACACAGATGACCGTCCTTATAACAGTAATTATGCAACTCTGACACCGGGACGCTCTTTCTATGTCAGTCTGCTG
GTTCGTTTCAAGCAATAA

Upstream 100 bases:

>100_bases
CTTTTCAGGGTGAAGCCAGGAAACCTGCCAGGTCTGAACATAGATAATTCACGCTTTCCCGGGGCCAGGAAAGCTAATTA
TTAATTCTTAAATTATTTCG

Downstream 100 bases:

>100_bases
AACTATTTTTAGCATGACCTCTAAAACCAGACTTGTCTATCTGCTCATAACAACTTTCTGCCTGGCAGGTTGCGGCTATA
AAAGCCGCAACCCGGTGAGT

Product: putative TonB-dependent outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MKKKCLLTALFGCMVVCASAQISLSGKVVDARTGKPVEGANVRLEQTTIGCATNPKGEFLLKDIKEGTYTLRTSCLNYAP
VTQKVSQSQKEMVIRLKSTTFNMDQVVVTGTGTHHKLKDSPVPVEVISQRDLQNANPSSFQDALVKLVPSISVQTTAMGT
TLYVNGLPDKYLLVLINGKKVAGDISGSIDYDRINMDAVKRIEVLKGASSALYGSDAIAGVINIITDDPKSALNVSSNTR
VSSHGRISESVNADANDGKLSAHLNYNYRTSDGWQLNPYEESKGELVETTKKPVYKNHSHNVSQTLSYAATERLSLHLNG
NLFISENDRTGAYDYNNRHQSYTVGGTAKYLLAKRASYIEGNISTTNFRSFYDYINDAKTHKTGDEVLSKDQTYTNANLK
GVFKTHKNNTLFTGLDYVFEGLEPTETSKMLNNEYQSVYTLAAYVQDEVKLLDAISVVAGIRYAYNEKFKSQFTPKLSLM
YQYSELNVRASYAAGFRSPTLQQMYAVSESRGQITVGDPGLDPEKSNFYNLNIEYNHRLFSIAASIYQNDLKDKIEAEDI
GTTPEDIENGITRRRQYRNIEKARVKGFDIGFSVRPFTGFMFGANYIYTDGRNRTEDIRLERTVRHSGNFNASWRKTWND
YTFNIAINGRYQGTRWSKTYGNAPAHQLWDINTRHSFNLKSVALEPAVGVENIFNYTDDRPYNSNYATLTPGRSFYVSLL
VRFKQ

Sequences:

>Translated_725_residues
MKKKCLLTALFGCMVVCASAQISLSGKVVDARTGKPVEGANVRLEQTTIGCATNPKGEFLLKDIKEGTYTLRTSCLNYAP
VTQKVSQSQKEMVIRLKSTTFNMDQVVVTGTGTHHKLKDSPVPVEVISQRDLQNANPSSFQDALVKLVPSISVQTTAMGT
TLYVNGLPDKYLLVLINGKKVAGDISGSIDYDRINMDAVKRIEVLKGASSALYGSDAIAGVINIITDDPKSALNVSSNTR
VSSHGRISESVNADANDGKLSAHLNYNYRTSDGWQLNPYEESKGELVETTKKPVYKNHSHNVSQTLSYAATERLSLHLNG
NLFISENDRTGAYDYNNRHQSYTVGGTAKYLLAKRASYIEGNISTTNFRSFYDYINDAKTHKTGDEVLSKDQTYTNANLK
GVFKTHKNNTLFTGLDYVFEGLEPTETSKMLNNEYQSVYTLAAYVQDEVKLLDAISVVAGIRYAYNEKFKSQFTPKLSLM
YQYSELNVRASYAAGFRSPTLQQMYAVSESRGQITVGDPGLDPEKSNFYNLNIEYNHRLFSIAASIYQNDLKDKIEAEDI
GTTPEDIENGITRRRQYRNIEKARVKGFDIGFSVRPFTGFMFGANYIYTDGRNRTEDIRLERTVRHSGNFNASWRKTWND
YTFNIAINGRYQGTRWSKTYGNAPAHQLWDINTRHSFNLKSVALEPAVGVENIFNYTDDRPYNSNYATLTPGRSFYVSLL
VRFKQ
>Mature_725_residues
MKKKCLLTALFGCMVVCASAQISLSGKVVDARTGKPVEGANVRLEQTTIGCATNPKGEFLLKDIKEGTYTLRTSCLNYAP
VTQKVSQSQKEMVIRLKSTTFNMDQVVVTGTGTHHKLKDSPVPVEVISQRDLQNANPSSFQDALVKLVPSISVQTTAMGT
TLYVNGLPDKYLLVLINGKKVAGDISGSIDYDRINMDAVKRIEVLKGASSALYGSDAIAGVINIITDDPKSALNVSSNTR
VSSHGRISESVNADANDGKLSAHLNYNYRTSDGWQLNPYEESKGELVETTKKPVYKNHSHNVSQTLSYAATERLSLHLNG
NLFISENDRTGAYDYNNRHQSYTVGGTAKYLLAKRASYIEGNISTTNFRSFYDYINDAKTHKTGDEVLSKDQTYTNANLK
GVFKTHKNNTLFTGLDYVFEGLEPTETSKMLNNEYQSVYTLAAYVQDEVKLLDAISVVAGIRYAYNEKFKSQFTPKLSLM
YQYSELNVRASYAAGFRSPTLQQMYAVSESRGQITVGDPGLDPEKSNFYNLNIEYNHRLFSIAASIYQNDLKDKIEAEDI
GTTPEDIENGITRRRQYRNIEKARVKGFDIGFSVRPFTGFMFGANYIYTDGRNRTEDIRLERTVRHSGNFNASWRKTWND
YTFNIAINGRYQGTRWSKTYGNAPAHQLWDINTRHSFNLKSVALEPAVGVENIFNYTDDRPYNSNYATLTPGRSFYVSLL
VRFKQ

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=669, Percent_Identity=25.2615844544096, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1790405, Length=268, Percent_Identity=27.2388059701493, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81219; Mature: 81219

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKCLLTALFGCMVVCASAQISLSGKVVDARTGKPVEGANVRLEQTTIGCATNPKGEFL
CCCHHHHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCHH
LKDIKEGTYTLRTSCLNYAPVTQKVSQSQKEMVIRLKSTTFNMDQVVVTGTGTHHKLKDS
HHHHCCCCEEEEHHHCCCCCHHHHHHHCHHEEEEEEECCEECCCEEEEEECCCCCCCCCC
PVPVEVISQRDLQNANPSSFQDALVKLVPSISVQTTAMGTTLYVNGLPDKYLLVLINGKK
CCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCEEEEEECCCE
VAGDISGSIDYDRINMDAVKRIEVLKGASSALYGSDAIAGVINIITDDPKSALNVSSNTR
EECCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHEEECCCCHHHCCCCCCCE
VSSHGRISESVNADANDGKLSAHLNYNYRTSDGWQLNPYEESKGELVETTKKPVYKNHSH
ECCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEECCCCCCCCCHHHHCCCCCCCCCCC
NVSQTLSYAATERLSLHLNGNLFISENDRTGAYDYNNRHQSYTVGGTAKYLLAKRASYIE
CHHHHHHHHEEEEEEEEECCEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHC
GNISTTNFRSFYDYINDAKTHKTGDEVLSKDQTYTNANLKGVFKTHKNNTLFTGLDYVFE
CCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEHHHHHC
GLEPTETSKMLNNEYQSVYTLAAYVQDEVKLLDAISVVAGIRYAYNEKFKSQFTPKLSLM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
YQYSELNVRASYAAGFRSPTLQQMYAVSESRGQITVGDPGLDPEKSNFYNLNIEYNHRLF
EEEECCEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEEECCHHH
SIAASIYQNDLKDKIEAEDIGTTPEDIENGITRRRQYRNIEKARVKGFDIGFSVRPFTGF
HHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCHHHHHEEEEECCEEECCCEEE
MFGANYIYTDGRNRTEDIRLERTVRHSGNFNASWRKTWNDYTFNIAINGRYQGTRWSKTY
EECCCEEEECCCCCCHHEEEEEHHHCCCCCCCHHEECCCCEEEEEEEECEECCCCCCCCC
GNAPAHQLWDINTRHSFNLKSVALEPAVGVENIFNYTDDRPYNSNYATLTPGRSFYVSLL
CCCCCHHEEECCCCCCCCCHHEEECCCCCHHHHHCCCCCCCCCCCEEEECCCHHHHHHHH
VRFKQ
HHCCC
>Mature Secondary Structure
MKKKCLLTALFGCMVVCASAQISLSGKVVDARTGKPVEGANVRLEQTTIGCATNPKGEFL
CCCHHHHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCHH
LKDIKEGTYTLRTSCLNYAPVTQKVSQSQKEMVIRLKSTTFNMDQVVVTGTGTHHKLKDS
HHHHCCCCEEEEHHHCCCCCHHHHHHHCHHEEEEEEECCEECCCEEEEEECCCCCCCCCC
PVPVEVISQRDLQNANPSSFQDALVKLVPSISVQTTAMGTTLYVNGLPDKYLLVLINGKK
CCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCEEEEEECCCE
VAGDISGSIDYDRINMDAVKRIEVLKGASSALYGSDAIAGVINIITDDPKSALNVSSNTR
EECCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHEEECCCCHHHCCCCCCCE
VSSHGRISESVNADANDGKLSAHLNYNYRTSDGWQLNPYEESKGELVETTKKPVYKNHSH
ECCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEECCCCCCCCCHHHHCCCCCCCCCCC
NVSQTLSYAATERLSLHLNGNLFISENDRTGAYDYNNRHQSYTVGGTAKYLLAKRASYIE
CHHHHHHHHEEEEEEEEECCEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHC
GNISTTNFRSFYDYINDAKTHKTGDEVLSKDQTYTNANLKGVFKTHKNNTLFTGLDYVFE
CCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEHHHHHC
GLEPTETSKMLNNEYQSVYTLAAYVQDEVKLLDAISVVAGIRYAYNEKFKSQFTPKLSLM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
YQYSELNVRASYAAGFRSPTLQQMYAVSESRGQITVGDPGLDPEKSNFYNLNIEYNHRLF
EEEECCEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEEECCHHH
SIAASIYQNDLKDKIEAEDIGTTPEDIENGITRRRQYRNIEKARVKGFDIGFSVRPFTGF
HHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCHHHHHEEEEECCEEECCCEEE
MFGANYIYTDGRNRTEDIRLERTVRHSGNFNASWRKTWNDYTFNIAINGRYQGTRWSKTY
EECCCEEEECCCCCCHHEEEEEHHHCCCCCCCHHEECCCCEEEEEEEECEECCCCCCCCC
GNAPAHQLWDINTRHSFNLKSVALEPAVGVENIFNYTDDRPYNSNYATLTPGRSFYVSLL
CCCCCHHEEECCCCCCCCCHHEEECCCCCHHHHHCCCCCCCCCCCEEEECCCHHHHHHHH
VRFKQ
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]