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The map label for this gene is nrdF [H]

Identifier: 150005609

GI number: 150005609

Start: 3915794

End: 3916843

Strand: Reverse

Name: nrdF [H]

Synonym: BVU_3097

Alternate gene names: 150005609

Gene position: 3916843-3915794 (Counterclockwise)

Preceding gene: 150005610

Following gene: 150005604

Centisome position: 75.86

GC content: 39.43

Gene sequence:

>1050_bases
ATGAATACAATAAAATTAAAAAAGAATGCCCTTTTCAATCCTGAGGGAGATACCGACCTCCGTCACAGAAGAATGATTGG
AGGAAACACCACCAATTTGAATGATTTCAATAATATGCGCTACAAATGGGTTAGTGACTGGTATCGTCAGGCCATGAATA
ATTTTTGGATTCCCGAAGAAATCAATCTCACCCAAGACACCAAGGATTATCCTCACCTGGACCAGGCAGAACGCACCGCC
TATGATAAAATCCTGAGTTTTTTAGTGTTCCTTGATTCTTTACAAAGCAATAATCTGCCCACCATCAGCGAATACATCAC
AGCCAATGAAGTTAATCTATGCCTCCATATCCAAGCCTTTCAGGAATGTGTACACAGCCAAAGCTACAGTTACATGCTGG
ATTCTATCTGTAGCCCCGAAAAGCGTAACGAGATCCTTTACCAATGGAAGACAGACGGACACCTGCTGAAAAGAAATACC
TTTATAGGCAATTGCTATAACGAATTTCAGGAAAGTCAGGATGGATTCACATTGATGAAAACCCTTATCGCCAACTATAT
ATTGGAAGGAATCTATTTCTATAGCGGATTCATGTTTTTCTATAACTTGAGCCGTAATGGAAAAATGTCAGGTTCCGCAC
AAGAAATCCGATATATCAATCGAGATGAAAACACGCATCTGTGGTTATTCCGCAACATTATTCTGGAATTAAAGAAAGAG
GAACCGGATTTATTCACTCCCGATAAAGTAAAAATATATGAATACATGATGCGTGAGGGGGTCAAGCAGGAAATAGAATG
GGGACAATATGTGATAGGAGACAATATACAGGGACTCAACCGGAAAATGATAGAAGATTATATTCAATATTTAGGCAATC
TCCGTTGGAGTAGTTTAGGTTTTGGCCCTCTGTACGAAGAAAACCATAAAGAGCCGGAAAGCATGCACTGGGTATCTCAA
TATTCCAATGCCAATATGGTAAAGACTGATTTTTTTGAAGCAAAGAGTACGGCTTATGCCAAAAGCACAGCTTTGGAAGA
TGACTTATAA

Upstream 100 bases:

>100_bases
GCTTGCGCCCCTACAAGAAATGAATAACAAATTTATTTTTAATATACAGCCTTGAGTTAGCAGTAAAACAAGAAGACAGA
ATATAAAACAACAATAAATC

Downstream 100 bases:

>100_bases
CCCATTTACAAAATAATTTTGCTCCGCATCTTAAACCGTTAAGATACGGAGCAATAAATGACCTGACAGAAACATTTCCA
TTAAAGACTATCAATAAACA

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNTIKLKKNALFNPEGDTDLRHRRMIGGNTTNLNDFNNMRYKWVSDWYRQAMNNFWIPEEINLTQDTKDYPHLDQAERTA
YDKILSFLVFLDSLQSNNLPTISEYITANEVNLCLHIQAFQECVHSQSYSYMLDSICSPEKRNEILYQWKTDGHLLKRNT
FIGNCYNEFQESQDGFTLMKTLIANYILEGIYFYSGFMFFYNLSRNGKMSGSAQEIRYINRDENTHLWLFRNIILELKKE
EPDLFTPDKVKIYEYMMREGVKQEIEWGQYVIGDNIQGLNRKMIEDYIQYLGNLRWSSLGFGPLYEENHKEPESMHWVSQ
YSNANMVKTDFFEAKSTAYAKSTALEDDL

Sequences:

>Translated_349_residues
MNTIKLKKNALFNPEGDTDLRHRRMIGGNTTNLNDFNNMRYKWVSDWYRQAMNNFWIPEEINLTQDTKDYPHLDQAERTA
YDKILSFLVFLDSLQSNNLPTISEYITANEVNLCLHIQAFQECVHSQSYSYMLDSICSPEKRNEILYQWKTDGHLLKRNT
FIGNCYNEFQESQDGFTLMKTLIANYILEGIYFYSGFMFFYNLSRNGKMSGSAQEIRYINRDENTHLWLFRNIILELKKE
EPDLFTPDKVKIYEYMMREGVKQEIEWGQYVIGDNIQGLNRKMIEDYIQYLGNLRWSSLGFGPLYEENHKEPESMHWVSQ
YSNANMVKTDFFEAKSTAYAKSTALEDDL
>Mature_349_residues
MNTIKLKKNALFNPEGDTDLRHRRMIGGNTTNLNDFNNMRYKWVSDWYRQAMNNFWIPEEINLTQDTKDYPHLDQAERTA
YDKILSFLVFLDSLQSNNLPTISEYITANEVNLCLHIQAFQECVHSQSYSYMLDSICSPEKRNEILYQWKTDGHLLKRNT
FIGNCYNEFQESQDGFTLMKTLIANYILEGIYFYSGFMFFYNLSRNGKMSGSAQEIRYINRDENTHLWLFRNIILELKKE
EPDLFTPDKVKIYEYMMREGVKQEIEWGQYVIGDNIQGLNRKMIEDYIQYLGNLRWSSLGFGPLYEENHKEPESMHWVSQ
YSNANMVKTDFFEAKSTAYAKSTALEDDL

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI42544136, Length=315, Percent_Identity=22.5396825396825, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI289177074, Length=306, Percent_Identity=22.8758169934641, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4557845, Length=268, Percent_Identity=22.7611940298507, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI260064013, Length=268, Percent_Identity=22.7611940298507, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI289177076, Length=307, Percent_Identity=23.4527687296417, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788567, Length=350, Percent_Identity=23.4285714285714, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789031, Length=299, Percent_Identity=25.752508361204, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551968, Length=307, Percent_Identity=23.7785016286645, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193206379, Length=261, Percent_Identity=22.6053639846743, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322434, Length=311, Percent_Identity=24.1157556270096, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI18079279, Length=317, Percent_Identity=25.2365930599369, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 41347; Mature: 41347

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIKLKKNALFNPEGDTDLRHRRMIGGNTTNLNDFNNMRYKWVSDWYRQAMNNFWIPEE
CCCEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
INLTQDTKDYPHLDQAERTAYDKILSFLVFLDSLQSNNLPTISEYITANEVNLCLHIQAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEHHHH
QECVHSQSYSYMLDSICSPEKRNEILYQWKTDGHLLKRNTFIGNCYNEFQESQDGFTLMK
HHHHHCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCEEHHHHHHHHHCCCHHHHHH
TLIANYILEGIYFYSGFMFFYNLSRNGKMSGSAQEIRYINRDENTHLWLFRNIILELKKE
HHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHEECCCCCCEEHHHHHHHHHHHCC
EPDLFTPDKVKIYEYMMREGVKQEIEWGQYVIGDNIQGLNRKMIEDYIQYLGNLRWSSLG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
FGPLYEENHKEPESMHWVSQYSNANMVKTDFFEAKSTAYAKSTALEDDL
CCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNTIKLKKNALFNPEGDTDLRHRRMIGGNTTNLNDFNNMRYKWVSDWYRQAMNNFWIPEE
CCCEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
INLTQDTKDYPHLDQAERTAYDKILSFLVFLDSLQSNNLPTISEYITANEVNLCLHIQAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEHHHH
QECVHSQSYSYMLDSICSPEKRNEILYQWKTDGHLLKRNTFIGNCYNEFQESQDGFTLMK
HHHHHCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCEEHHHHHHHHHCCCHHHHHH
TLIANYILEGIYFYSGFMFFYNLSRNGKMSGSAQEIRYINRDENTHLWLFRNIILELKKE
HHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHEECCCCCCEEHHHHHHHHHHHCC
EPDLFTPDKVKIYEYMMREGVKQEIEWGQYVIGDNIQGLNRKMIEDYIQYLGNLRWSSLG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
FGPLYEENHKEPESMHWVSQYSNANMVKTDFFEAKSTAYAKSTALEDDL
CCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]