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The map label for this gene is pgl [H]

Identifier: 150005321

GI number: 150005321

Start: 3568850

End: 3569554

Strand: Direct

Name: pgl [H]

Synonym: BVU_2797

Alternate gene names: 150005321

Gene position: 3568850-3569554 (Clockwise)

Preceding gene: 150005320

Following gene: 150005324

Centisome position: 69.12

GC content: 46.24

Gene sequence:

>705_bases
ATGATTGACCATAACTTTTATGCGTCGCCTGTACAAGCGTCGCAAACCTTGATAACTCATATATTGGAAGCGATGGATAA
AGAGCTTGAACGGCCTTTTACCATTGCTCTTTCCGGAGGAACTACTCCTGCCACACTTTTTGAGGTTTGGGAGCGTGAAT
ATGCCGCATATACCCCTTGGTCCCGTATTTATTTCTATTGGGTAGACGAGCGTTGTGTGCCACCTGGCGATGATCAGAGC
AACTTTGGCTTGGCCTATCGTCTGTTGTTTAGTAAGGTAGGTATTCCCGCCAGTCATTGCTACCGTATTGTGGGTGAGGG
CGCTCCCGAAGAAGAAGCCAAACAGTATTCTTCCATAGTCAAGACCACCGTTCCGACCGTGGACGGTGTGCCTGTTTTTG
ATTTTGTATTATTAGGGATAGGAGAGGACGGGCATACATCATCCATTTTCCCCGACCATCAGGAACTTCTTACCGCCGGG
GAACCGTATGAGGTGTCCGTCAATCCTTATAATAAAACAGTGCGTATATGCATGACGGGACGTCCCTTGATAGAAGCCCG
GCATACCTGTTTTCTAGTGACGGGCGAGAACAAATGCAGTATTTTGAAAGAAATCCTTGATAAAAACAAGGAAGGGGTCT
ATCCGGCATCTTATATTTGGCATCATGCACGTAATTCGCAACTGTATGCATCACTTGTATCATAA

Upstream 100 bases:

>100_bases
AAGAATCTGACACATTCCAATTTATACTGTAAATTGTAAGTCGTCATCTGTGGATAGTAAATTTAAAACAGCAAACTCTA
AGTAATAAATAGTGAATAAG

Downstream 100 bases:

>100_bases
TATTTCTTTTAGATGAAGAGTTTAAACGAAAATAACTTTCTAGATGGGAAATGAATCAACTATGGATGCTATGTCTCCTA
TAGATATAAAAAAAGGAGCA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MIDHNFYASPVQASQTLITHILEAMDKELERPFTIALSGGTTPATLFEVWEREYAAYTPWSRIYFYWVDERCVPPGDDQS
NFGLAYRLLFSKVGIPASHCYRIVGEGAPEEEAKQYSSIVKTTVPTVDGVPVFDFVLLGIGEDGHTSSIFPDHQELLTAG
EPYEVSVNPYNKTVRICMTGRPLIEARHTCFLVTGENKCSILKEILDKNKEGVYPASYIWHHARNSQLYASLVS

Sequences:

>Translated_234_residues
MIDHNFYASPVQASQTLITHILEAMDKELERPFTIALSGGTTPATLFEVWEREYAAYTPWSRIYFYWVDERCVPPGDDQS
NFGLAYRLLFSKVGIPASHCYRIVGEGAPEEEAKQYSSIVKTTVPTVDGVPVFDFVLLGIGEDGHTSSIFPDHQELLTAG
EPYEVSVNPYNKTVRICMTGRPLIEARHTCFLVTGENKCSILKEILDKNKEGVYPASYIWHHARNSQLYASLVS
>Mature_234_residues
MIDHNFYASPVQASQTLITHILEAMDKELERPFTIALSGGTTPATLFEVWEREYAAYTPWSRIYFYWVDERCVPPGDDQS
NFGLAYRLLFSKVGIPASHCYRIVGEGAPEEEAKQYSSIVKTTVPTVDGVPVFDFVLLGIGEDGHTSSIFPDHQELLTAG
EPYEVSVNPYNKTVRICMTGRPLIEARHTCFLVTGENKCSILKEILDKNKEGVYPASYIWHHARNSQLYASLVS

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=198, Percent_Identity=34.8484848484849, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI52145310, Length=172, Percent_Identity=32.5581395348837, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115533058, Length=192, Percent_Identity=31.25, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533060, Length=192, Percent_Identity=30.7291666666667, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324362, Length=197, Percent_Identity=31.9796954314721, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319918, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321957, Length=223, Percent_Identity=29.1479820627803, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321687, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641119, Length=193, Percent_Identity=31.6062176165803, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 26316; Mature: 26316

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDHNFYASPVQASQTLITHILEAMDKELERPFTIALSGGTTPATLFEVWEREYAAYTPW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCC
SRIYFYWVDERCVPPGDDQSNFGLAYRLLFSKVGIPASHCYRIVGEGAPEEEAKQYSSIV
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHH
KTTVPTVDGVPVFDFVLLGIGEDGHTSSIFPDHQELLTAGEPYEVSVNPYNKTVRICMTG
HHHCCCCCCCCHHHHEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCEEEEEECC
RPLIEARHTCFLVTGENKCSILKEILDKNKEGVYPASYIWHHARNSQLYASLVS
CCHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHEECC
>Mature Secondary Structure
MIDHNFYASPVQASQTLITHILEAMDKELERPFTIALSGGTTPATLFEVWEREYAAYTPW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCC
SRIYFYWVDERCVPPGDDQSNFGLAYRLLFSKVGIPASHCYRIVGEGAPEEEAKQYSSIV
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHH
KTTVPTVDGVPVFDFVLLGIGEDGHTSSIFPDHQELLTAGEPYEVSVNPYNKTVRICMTG
HHHCCCCCCCCHHHHEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCEEEEEECC
RPLIEARHTCFLVTGENKCSILKEILDKNKEGVYPASYIWHHARNSQLYASLVS
CCHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]