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The map label for this gene is zwf [H]

Identifier: 150005320

GI number: 150005320

Start: 3567280

End: 3568788

Strand: Direct

Name: zwf [H]

Synonym: BVU_2796

Alternate gene names: 150005320

Gene position: 3567280-3568788 (Clockwise)

Preceding gene: 150005319

Following gene: 150005321

Centisome position: 69.09

GC content: 45.0

Gene sequence:

>1509_bases
ATGAGTTTACCACATAGTTTATTTTTGGTCATCTTCGGTGCATCCGGTGATTTAACCCGGCGCAAACTGATGCCTGCCTT
GATAAAGATACATAACGGGAAACGCTTCCCCGAGCATTTTGCCATTATCGGCTGTGCCCGTACTGCATACACGGACGAGA
CCTATCGTGCCTATCTGAAAGAAGAACTGATAAAATTCGGTTTTCTTACTAAAGAGGAAATGGAAACATTGGACGATTTT
CTCTCTACTGTTCATTACCAGTCCATGGACCCGGCTGACGAAACCACTTATTTTCTGTTGAATGACCGTTTGAAGGAGCT
TTCGCCTCAATATGAGAATAATGGGAACTATTTGTTCTATCTGGCAACTCCGCCCTTGCTTTATGAATTGATTCCGAAAT
GTCTGCATGATGCGGGCTTGTTGAAAAAGCCTGGATTAAAGCGTATCATTGTCGAGAAGCCTTTCGGATACGACCTGGCT
TCCGCTCAGAAACTAAATAAAATCTATGCCGCTTATTTTAAAGAAGAGGATATCTACCGCATCGATCATTTTCTGGGCAA
GGAAACGGTGCAGAATATTATGGTGACCCGTTTTGGAAGTACTATTTACGAACCGATATGGAACCGTAACTATATAGATT
ATGTAGAAATCACTGCGGTGGAAAATATGGGTATAGGTACTCGCGGAGGATATTATGACGGGGCGGGAGCTCTGCGCGAT
ATGGTACAGAACCATTTGATGCAGTTGCTTGCTATTACTGCCATGGAACCACCGGCCAAGTTTGACAAGAATGGTTTCCG
TAACGAGGTGATCAAGGTCTACCAATCCCTTCGTCCGCTGACTGATAAGTATATCCGTGATAATGTCATCCGCGGACAAT
ATATTGCTGGTGATGACCGTATCGGTTATCGTGAAGAAAAGAATGTTCGTCCTGATTCCCGTACAGATACCTACGTGGCG
ATGTGTCTGTATGTGGATAACTGGCGTTGGCAGGGAGTGCCTTTTTATATCCGTACCGGAAAGCAGATGCCTACCAAGGT
GACCGAAATTGTGGTTCATTTCAAACCTGCTCCTATGCAGATGTTCCAAATGAAGGAAGGCTTTTACAAAGGTGAGGAAC
TGATTATCCGTATTCAACCCGACGAGGGAATTCTTCAGCGCATAGCCATGAAAGAACCTGGTGCCGGTTTCTATATGGGA
ACCATGGAGATGGACTTCAGCTATGACCAGCACGATCAGGAAACGGGGGATGCGTATGTACGCCTGTTGGAAGACAGTCT
GGTGGGTGATCCTACACTTTTTACCCGTTCCGATGCTGTGGACGAGAGCTGGACTTACTTTGATAAGATTCTGGATTATT
GGAAGAAGCATCCCGAAACTCCTCTTTATGGGTATCCTGCAGGAACATGGGGACCGAAAGAAGCGGATGTATTGATCAAC
CGCAGTCATTCCGAATGGACAAACCCGTGCAAGAATCTGACACATTCCAATTTATACTGTAAATTGTAA

Upstream 100 bases:

>100_bases
GGACAGTCCACGGGGGGAATTTTTCCACGAACATTGGGAAGACAACTATTGATATGTCGCAACACAAAGCATTATACATT
CATTTTTAAAAGAAAGAATC

Downstream 100 bases:

>100_bases
GTCGTCATCTGTGGATAGTAAATTTAAAACAGCAAACTCTAAGTAATAAATAGTGAATAAGATGATTGACCATAACTTTT
ATGCGTCGCCTGTACAAGCG

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSLPHSLFLVIFGASGDLTRRKLMPALIKIHNGKRFPEHFAIIGCARTAYTDETYRAYLKEELIKFGFLTKEEMETLDDF
LSTVHYQSMDPADETTYFLLNDRLKELSPQYENNGNYLFYLATPPLLYELIPKCLHDAGLLKKPGLKRIIVEKPFGYDLA
SAQKLNKIYAAYFKEEDIYRIDHFLGKETVQNIMVTRFGSTIYEPIWNRNYIDYVEITAVENMGIGTRGGYYDGAGALRD
MVQNHLMQLLAITAMEPPAKFDKNGFRNEVIKVYQSLRPLTDKYIRDNVIRGQYIAGDDRIGYREEKNVRPDSRTDTYVA
MCLYVDNWRWQGVPFYIRTGKQMPTKVTEIVVHFKPAPMQMFQMKEGFYKGEELIIRIQPDEGILQRIAMKEPGAGFYMG
TMEMDFSYDQHDQETGDAYVRLLEDSLVGDPTLFTRSDAVDESWTYFDKILDYWKKHPETPLYGYPAGTWGPKEADVLIN
RSHSEWTNPCKNLTHSNLYCKL

Sequences:

>Translated_502_residues
MSLPHSLFLVIFGASGDLTRRKLMPALIKIHNGKRFPEHFAIIGCARTAYTDETYRAYLKEELIKFGFLTKEEMETLDDF
LSTVHYQSMDPADETTYFLLNDRLKELSPQYENNGNYLFYLATPPLLYELIPKCLHDAGLLKKPGLKRIIVEKPFGYDLA
SAQKLNKIYAAYFKEEDIYRIDHFLGKETVQNIMVTRFGSTIYEPIWNRNYIDYVEITAVENMGIGTRGGYYDGAGALRD
MVQNHLMQLLAITAMEPPAKFDKNGFRNEVIKVYQSLRPLTDKYIRDNVIRGQYIAGDDRIGYREEKNVRPDSRTDTYVA
MCLYVDNWRWQGVPFYIRTGKQMPTKVTEIVVHFKPAPMQMFQMKEGFYKGEELIIRIQPDEGILQRIAMKEPGAGFYMG
TMEMDFSYDQHDQETGDAYVRLLEDSLVGDPTLFTRSDAVDESWTYFDKILDYWKKHPETPLYGYPAGTWGPKEADVLIN
RSHSEWTNPCKNLTHSNLYCKL
>Mature_501_residues
SLPHSLFLVIFGASGDLTRRKLMPALIKIHNGKRFPEHFAIIGCARTAYTDETYRAYLKEELIKFGFLTKEEMETLDDFL
STVHYQSMDPADETTYFLLNDRLKELSPQYENNGNYLFYLATPPLLYELIPKCLHDAGLLKKPGLKRIIVEKPFGYDLAS
AQKLNKIYAAYFKEEDIYRIDHFLGKETVQNIMVTRFGSTIYEPIWNRNYIDYVEITAVENMGIGTRGGYYDGAGALRDM
VQNHLMQLLAITAMEPPAKFDKNGFRNEVIKVYQSLRPLTDKYIRDNVIRGQYIAGDDRIGYREEKNVRPDSRTDTYVAM
CLYVDNWRWQGVPFYIRTGKQMPTKVTEIVVHFKPAPMQMFQMKEGFYKGEELIIRIQPDEGILQRIAMKEPGAGFYMGT
MEMDFSYDQHDQETGDAYVRLLEDSLVGDPTLFTRSDAVDESWTYFDKILDYWKKHPETPLYGYPAGTWGPKEADVLINR
SHSEWTNPCKNLTHSNLYCKL

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=496, Percent_Identity=36.6935483870968, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI109389365, Length=497, Percent_Identity=36.6197183098592, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI52145310, Length=356, Percent_Identity=29.7752808988764, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1788158, Length=488, Percent_Identity=38.9344262295082, Blast_Score=342, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17538218, Length=482, Percent_Identity=35.6846473029046, Blast_Score=304, Evalue=9e-83,
Organism=Saccharomyces cerevisiae, GI6324088, Length=476, Percent_Identity=33.8235294117647, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24643350, Length=482, Percent_Identity=37.344398340249, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24643352, Length=482, Percent_Identity=37.344398340249, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI221513548, Length=477, Percent_Identity=28.0922431865828, Blast_Score=189, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 58276; Mature: 58145

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPHSLFLVIFGASGDLTRRKLMPALIKIHNGKRFPEHFAIIGCARTAYTDETYRAYLK
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHEEEEEHHHHCCCHHHHHHHH
EELIKFGFLTKEEMETLDDFLSTVHYQSMDPADETTYFLLNDRLKELSPQYENNGNYLFY
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHCCCCCCCCCCEEEE
LATPPLLYELIPKCLHDAGLLKKPGLKRIIVEKPFGYDLASAQKLNKIYAAYFKEEDIYR
ECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHH
IDHFLGKETVQNIMVTRFGSTIYEPIWNRNYIDYVEITAVENMGIGTRGGYYDGAGALRD
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHH
MVQNHLMQLLAITAMEPPAKFDKNGFRNEVIKVYQSLRPLTDKYIRDNVIRGQYIAGDDR
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
IGYREEKNVRPDSRTDTYVAMCLYVDNWRWQGVPFYIRTGKQMPTKVTEIVVHFKPAPMQ
CCCCCCCCCCCCCCCCCEEEEEEEEECCEECCCCEEEECCCCCCHHHHHEEEECCCCCHH
MFQMKEGFYKGEELIIRIQPDEGILQRIAMKEPGAGFYMGTMEMDFSYDQHDQETGDAYV
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHH
RLLEDSLVGDPTLFTRSDAVDESWTYFDKILDYWKKHPETPLYGYPAGTWGPKEADVLIN
HHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
RSHSEWTNPCKNLTHSNLYCKL
CCCHHHCCHHHCCCCCCCEEEC
>Mature Secondary Structure 
SLPHSLFLVIFGASGDLTRRKLMPALIKIHNGKRFPEHFAIIGCARTAYTDETYRAYLK
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHEEEEEHHHHCCCHHHHHHHH
EELIKFGFLTKEEMETLDDFLSTVHYQSMDPADETTYFLLNDRLKELSPQYENNGNYLFY
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHCCCCCCCCCCEEEE
LATPPLLYELIPKCLHDAGLLKKPGLKRIIVEKPFGYDLASAQKLNKIYAAYFKEEDIYR
ECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHH
IDHFLGKETVQNIMVTRFGSTIYEPIWNRNYIDYVEITAVENMGIGTRGGYYDGAGALRD
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHH
MVQNHLMQLLAITAMEPPAKFDKNGFRNEVIKVYQSLRPLTDKYIRDNVIRGQYIAGDDR
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
IGYREEKNVRPDSRTDTYVAMCLYVDNWRWQGVPFYIRTGKQMPTKVTEIVVHFKPAPMQ
CCCCCCCCCCCCCCCCCEEEEEEEEECCEECCCCEEEECCCCCCHHHHHEEEECCCCCHH
MFQMKEGFYKGEELIIRIQPDEGILQRIAMKEPGAGFYMGTMEMDFSYDQHDQETGDAYV
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHH
RLLEDSLVGDPTLFTRSDAVDESWTYFDKILDYWKKHPETPLYGYPAGTWGPKEADVLIN
HHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
RSHSEWTNPCKNLTHSNLYCKL
CCCHHHCCHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]