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The map label for this gene is ribE [H]

Identifier: 150005249

GI number: 150005249

Start: 3465372

End: 3465974

Strand: Direct

Name: ribE [H]

Synonym: BVU_2721

Alternate gene names: 150005249

Gene position: 3465372-3465974 (Clockwise)

Preceding gene: 150005246

Following gene: 150005253

Centisome position: 67.12

GC content: 44.78

Gene sequence:

>603_bases
ATGTTCTCAGGGATTGTAGAAGAATATGCGGAGGTGGTGCGTATTGTAAAGGAGCAGGAAAATCTGCACCTCACCTTGAA
ATGTTCGTTTGTGGACGAACTGAAAATAGACCAGAGTATCTCTCATAACGGTGTGTGCCTGACTGTAGTCAGTTTACAGG
ATGGAACGTACACGGTTACCGCCATGAAAGAAACGATAGAGCGTTCCAACATCGGCTTGCTGAAAGTGGGAGATAAAGTG
AATGTGGAACGCAGCATGATGATGAACGGGCGGCTGGACGGTCATATTGTGCAAGGACATGTGGATCAGACTGCCGAATG
TATGGATATAAAGGATGCTGAAGGGAGCTGGTATTTTACTTTCAGATATGCGTTTGACAAGGAAATGGCAAAGCGCGGCT
ACATCACGGTGGACAAAGGCTCGGTTACGGTGAATGGTGTGAGTCTGACCGTTTGTAACCCTACGGAGGATACTTTTCAG
GTTGCCATCATTCCTTATACTTACGAACATACCAATTTCCATACTTTTAAAGTGGGAAGCATTGTGAATATAGAGTTTGA
TATCATCGGCAAATATTTAAGCCGCATGATGCAGTTCTCCTGA

Upstream 100 bases:

>100_bases
ACGAATTGCCGGTCATTTGTCATTAACCGTCGGTAAGTTTCGAATATTTGTGTTTTTTGTTCTATCTTTGTTCTCGAAAC
TTAATTAAAGACTAAAACTT

Downstream 100 bases:

>100_bases
TTCTTTTACCGCAGGTTGCACAGATGATTGTTGAAGATGAAAGAAACTTCTTTGTGGAAATCCGGAATTATCCGCATCGG
CTTTTGAGCAAAAAAGAATC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MFSGIVEEYAEVVRIVKEQENLHLTLKCSFVDELKIDQSISHNGVCLTVVSLQDGTYTVTAMKETIERSNIGLLKVGDKV
NVERSMMMNGRLDGHIVQGHVDQTAECMDIKDAEGSWYFTFRYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTEDTFQ
VAIIPYTYEHTNFHTFKVGSIVNIEFDIIGKYLSRMMQFS

Sequences:

>Translated_200_residues
MFSGIVEEYAEVVRIVKEQENLHLTLKCSFVDELKIDQSISHNGVCLTVVSLQDGTYTVTAMKETIERSNIGLLKVGDKV
NVERSMMMNGRLDGHIVQGHVDQTAECMDIKDAEGSWYFTFRYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTEDTFQ
VAIIPYTYEHTNFHTFKVGSIVNIEFDIIGKYLSRMMQFS
>Mature_200_residues
MFSGIVEEYAEVVRIVKEQENLHLTLKCSFVDELKIDQSISHNGVCLTVVSLQDGTYTVTAMKETIERSNIGLLKVGDKV
NVERSMMMNGRLDGHIVQGHVDQTAECMDIKDAEGSWYFTFRYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTEDTFQ
VAIIPYTYEHTNFHTFKVGSIVNIEFDIIGKYLSRMMQFS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=190, Percent_Identity=38.4210526315789, Blast_Score=111, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=173, Percent_Identity=34.6820809248555, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22634; Mature: 22634

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIVEEYAEVVRIVKEQENLHLTLKCSFVDELKIDQSISHNGVCLTVVSLQDGTYTVT
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEE
AMKETIERSNIGLLKVGDKVNVERSMMMNGRLDGHIVQGHVDQTAECMDIKDAEGSWYFT
EEHHHHHHCCCCEEEECCCCCCCHHEEECCCCCCEEEECCCCCCCEEEEEECCCCCEEEE
FRYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTEDTFQVAIIPYTYEHTNFHTFKVGS
EEEEECHHHHHCCCEEEECCCEEEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEEECE
IVNIEFDIIGKYLSRMMQFS
EEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSGIVEEYAEVVRIVKEQENLHLTLKCSFVDELKIDQSISHNGVCLTVVSLQDGTYTVT
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEE
AMKETIERSNIGLLKVGDKVNVERSMMMNGRLDGHIVQGHVDQTAECMDIKDAEGSWYFT
EEHHHHHHCCCCEEEECCCCCCCHHEEECCCCCCEEEECCCCCCCEEEEEECCCCCEEEE
FRYAFDKEMAKRGYITVDKGSVTVNGVSLTVCNPTEDTFQVAIIPYTYEHTNFHTFKVGS
EEEEECHHHHHCCCEEEECCCEEEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEEECE
IVNIEFDIIGKYLSRMMQFS
EEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]