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The map label for this gene is ntrC [H]

Identifier: 150005142

GI number: 150005142

Start: 3323551

End: 3324816

Strand: Direct

Name: ntrC [H]

Synonym: BVU_2609

Alternate gene names: 150005142

Gene position: 3323551-3324816 (Clockwise)

Preceding gene: 150005141

Following gene: 150005143

Centisome position: 64.37

GC content: 43.05

Gene sequence:

>1266_bases
ATGGTTAGGTCAGAAATACAAAATGTAAAGCTCAGATTTGGTATTATTGGTAATGCCGAAGGGTTGAACCGTGCCATAGA
CGTGGCTATCCAGGTGGCACCCACTGATTTGTCAGTGTTGATCACCGGTGAAAGTGGGGTGGGAAAGGAAAATTTCCCAC
AGATTATTCATCAGTTCAGTCGCCGTAAACATGGACAGTATATAGCGGTGAACTGTGGGGCTATTCCTGAAGGTACTATA
GATTCAGAGCTTTTCGGACATGAAAAAGGTGCTTTTACGGGCGCTATCAGTGACCGTAATGGCTATTTTGCCGAAGCCAA
TGGTGGAACCATTTTTCTGGATGAAGTAGGAGAGTTGCCTCTTGCTACTCAGGCACGTCTGTTACGTGTACTTGAAAGTG
GTGAATTCATTAAGGTAGGTTCATCTAAAGTGCAGAAAACGGATGTGCGTATTGTTGCCGCTACCAATGTGAATCTGACG
GAAGCCATTGCTGAAGGTCGTTTTCGTGAGGATTTGTATTATCGTTTGAACACTGTACCTATTAAAATACCTCCTTTGCG
TGAGCGTGGAGATGATATAACTTTACTTTTCCGTAAATTTGCATCAGATTTTGCTGAGAAATATCGTATGCCGGCTATCC
AGTTGACAGAAGATGCGAAAGTTTTGTTGCTGGCTTATTCGTGGCCCGGTAATGTGCGCCAGTTGAAAAACATCACTGAA
CAGATATCTATTATTGAAACTAACCGGGATATAACGGCAGAGATTTTGAGAAATTATTTACCAGAGCAACATGTGAATTC
TGGTTTGCCTGCTTTGTTTGGAGTGAAAGCAAATACAGGGAAGGCTTTTGAAAGTGAGCGTGAGATTTTGTATCAGGTGT
TGTTTGATATGCGGCGTGATGTGACTGACTTGAAGAAGTTAGTCAATACACTGATGGCGGAACGTGGCGCGCAATCTGTT
CCGACGGCACCAGCTACTACGGCAGTTTCTTATTATCAGGAACCGCAACGGAATTTAGTTGCTACAGTGGTGCCTGCTAC
GCCTACCATAATTTCTGCCGCCAAACCGGCTCATCCTGTAGTAGATGATATTCAGGATACGGAGGAGGTTGTAGAAGAAG
CCACTTTGTCATTGGACGAAGTGGAGAAAGAAATGATACGTAAGGCGCTCGACCGTCATCATGGAAAGCGTAAGAATGCA
GCAAAAGATTTGAATATTTCAGAACGAACACTTTATAGAAAAATAAAAGAATATGGTTTGGATTAA

Upstream 100 bases:

>100_bases
GTATCTATCCGTGAAATCCACGTCTTATTTTTTATTTTTCTGCCATAATTTCTTGTTGTCTGCCTGAGAATTTGTAATTT
TGTCATATAATAGAGTGAAT

Downstream 100 bases:

>100_bases
ACAATTGAAAGTAGTTGGTGTGTTGATGGTACTGGCGGGGATCGTAACTGCTTGTTCTATTTCATATAAATTTAACGGAT
CGTCTATAGATTATACAAAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MVRSEIQNVKLRFGIIGNAEGLNRAIDVAIQVAPTDLSVLITGESGVGKENFPQIIHQFSRRKHGQYIAVNCGAIPEGTI
DSELFGHEKGAFTGAISDRNGYFAEANGGTIFLDEVGELPLATQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLT
EAIAEGRFREDLYYRLNTVPIKIPPLRERGDDITLLFRKFASDFAEKYRMPAIQLTEDAKVLLLAYSWPGNVRQLKNITE
QISIIETNRDITAEILRNYLPEQHVNSGLPALFGVKANTGKAFESEREILYQVLFDMRRDVTDLKKLVNTLMAERGAQSV
PTAPATTAVSYYQEPQRNLVATVVPATPTIISAAKPAHPVVDDIQDTEEVVEEATLSLDEVEKEMIRKALDRHHGKRKNA
AKDLNISERTLYRKIKEYGLD

Sequences:

>Translated_421_residues
MVRSEIQNVKLRFGIIGNAEGLNRAIDVAIQVAPTDLSVLITGESGVGKENFPQIIHQFSRRKHGQYIAVNCGAIPEGTI
DSELFGHEKGAFTGAISDRNGYFAEANGGTIFLDEVGELPLATQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLT
EAIAEGRFREDLYYRLNTVPIKIPPLRERGDDITLLFRKFASDFAEKYRMPAIQLTEDAKVLLLAYSWPGNVRQLKNITE
QISIIETNRDITAEILRNYLPEQHVNSGLPALFGVKANTGKAFESEREILYQVLFDMRRDVTDLKKLVNTLMAERGAQSV
PTAPATTAVSYYQEPQRNLVATVVPATPTIISAAKPAHPVVDDIQDTEEVVEEATLSLDEVEKEMIRKALDRHHGKRKNA
AKDLNISERTLYRKIKEYGLD
>Mature_421_residues
MVRSEIQNVKLRFGIIGNAEGLNRAIDVAIQVAPTDLSVLITGESGVGKENFPQIIHQFSRRKHGQYIAVNCGAIPEGTI
DSELFGHEKGAFTGAISDRNGYFAEANGGTIFLDEVGELPLATQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLT
EAIAEGRFREDLYYRLNTVPIKIPPLRERGDDITLLFRKFASDFAEKYRMPAIQLTEDAKVLLLAYSWPGNVRQLKNITE
QISIIETNRDITAEILRNYLPEQHVNSGLPALFGVKANTGKAFESEREILYQVLFDMRRDVTDLKKLVNTLMAERGAQSV
PTAPATTAVSYYQEPQRNLVATVVPATPTIISAAKPAHPVVDDIQDTEEVVEEATLSLDEVEKEMIRKALDRHHGKRKNA
AKDLNISERTLYRKIKEYGLD

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=254, Percent_Identity=44.8818897637795, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1790299, Length=407, Percent_Identity=34.6437346437346, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1788905, Length=263, Percent_Identity=44.4866920152091, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI1790437, Length=283, Percent_Identity=40.6360424028269, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87082152, Length=305, Percent_Identity=40, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789087, Length=242, Percent_Identity=44.2148760330579, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI1789233, Length=255, Percent_Identity=41.5686274509804, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI87082117, Length=280, Percent_Identity=39.6428571428571, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=44.2982456140351, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786524, Length=268, Percent_Identity=40.2985074626866, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1787583, Length=231, Percent_Identity=41.5584415584416, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1789828, Length=290, Percent_Identity=32.0689655172414, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87081858, Length=241, Percent_Identity=31.9502074688797, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 46859; Mature: 46859

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSEIQNVKLRFGIIGNAEGLNRAIDVAIQVAPTDLSVLITGESGVGKENFPQIIHQFS
CCCCHHCCEEEEEEEEECCHHHCCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHH
RRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAISDRNGYFAEANGGTIFLDEVGELP
HCCCCCEEEEECCCCCCCCCCHHHHCCCCCCEEEEEECCCCEEEECCCCEEEEECCCCCC
LATQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTEAIAEGRFREDLYYRLNTVP
CHHHHHHHHHHHCCCEEEECCCCCEECCEEEEEECCCCHHHHHHCCCHHHHHHEEEEEEE
IKIPPLRERGDDITLLFRKFASDFAEKYRMPAIQLTEDAKVLLLAYSWPGNVRQLKNITE
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCCCHHHHHHHHH
QISIIETNRDITAEILRNYLPEQHVNSGLPALFGVKANTGKAFESEREILYQVLFDMRRD
HHEEEECCCCHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
VTDLKKLVNTLMAERGAQSVPTAPATTAVSYYQEPQRNLVATVVPATPTIISAAKPAHPV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCCC
VDDIQDTEEVVEEATLSLDEVEKEMIRKALDRHHGKRKNAAKDLNISERTLYRKIKEYGL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
D
C
>Mature Secondary Structure
MVRSEIQNVKLRFGIIGNAEGLNRAIDVAIQVAPTDLSVLITGESGVGKENFPQIIHQFS
CCCCHHCCEEEEEEEEECCHHHCCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHH
RRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAISDRNGYFAEANGGTIFLDEVGELP
HCCCCCEEEEECCCCCCCCCCHHHHCCCCCCEEEEEECCCCEEEECCCCEEEEECCCCCC
LATQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTEAIAEGRFREDLYYRLNTVP
CHHHHHHHHHHHCCCEEEECCCCCEECCEEEEEECCCCHHHHHHCCCHHHHHHEEEEEEE
IKIPPLRERGDDITLLFRKFASDFAEKYRMPAIQLTEDAKVLLLAYSWPGNVRQLKNITE
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCCCHHHHHHHHH
QISIIETNRDITAEILRNYLPEQHVNSGLPALFGVKANTGKAFESEREILYQVLFDMRRD
HHEEEECCCCHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
VTDLKKLVNTLMAERGAQSVPTAPATTAVSYYQEPQRNLVATVVPATPTIISAAKPAHPV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCCC
VDDIQDTEEVVEEATLSLDEVEKEMIRKALDRHHGKRKNAAKDLNISERTLYRKIKEYGL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2881918; 11481430; 8478331 [H]