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The map label for this gene is 150005141

Identifier: 150005141

GI number: 150005141

Start: 3322077

End: 3323384

Strand: Direct

Name: 150005141

Synonym: BVU_2608

Alternate gene names: NA

Gene position: 3322077-3323384 (Clockwise)

Preceding gene: 150005139

Following gene: 150005142

Centisome position: 64.34

GC content: 41.21

Gene sequence:

>1308_bases
ATGGAAAAAATGAATGTGAAACCGGCAACCGGTAAATTAGGCGTTCTTTGTGTTGGATTGGGCGCTGTTACTTCAACTTT
TATGACAGGTGTGCTGATGGCTCGTAAGGGATTGGCAAAACCTGTCGGATCTATGACTCAATATGATAAAATGCGTGTTG
GCCGTGGAGAGAATAAAAAGTATTTGCATTATGGTGAAATTGTTCCATTGGCAAACTTAAATGACATTGTGTTTGGTGCA
TGGGATGTTTATCCGGCTAATGCTTATGAATCAGCGGTCAATGCTGAGGTTTTAAAAGAGAAAGATATTAATCCTGTAAA
GGATGAATTGGAGAAAATAGTTCCAATGAAAGCTGCTTTCGACCACAACTATGCTAGTCGTCTGGATGGTGATAATGTGA
AAGATTGCAAGAATCGTTGGGATATGATGGAACAGTTGCGTGAAGATATCCGCAATTTTAAAGTGGCTAACAATTGTGAC
CGTATTGTTGTTCTTTGGGCTGCTTCTACAGAGATTTATGTTCCTGTTGATGAAAAAATACACGGAACATTGGCAGCATT
GGAACAGGCTATGAAAGATGATGATAAGGCTCATATCGCTCCGTCTATGTGCTATGCTTATGCTGCACTGTCGGAAGGAT
GTCCTTTCATTATGGGAGCACCTAATACAACTGTTGATATTCCTGCTATGTGGGAGTTGGCTGAAAAGACTAAAATGCCT
ATTGCCGGCAAGGATTTCAAGACGGGTCAAACGTTGGTTAAATCAGGTTTCGCACCGATTATTGGAACCCGTTGTTTAGG
CTTGGACGGTTGGTTCTCTACAAACATTTTAGGTAATCGTGATGGTTTGGTGTTAGATGAGCCGGCTAACTTCCACACGA
AGGAGGTCAGCAAATTATCTACACTGGAATCTATTCTTGTTCCGGAAGATCAGCCGGACTTGTATACAGACTACTATCAT
AAAGTACGTATCAATTACTATCCGCCTCGTAATGATAATAAAGAAGGTTGGGATAATATTGATATCTTCGGATGGATGGG
GTATCCAATGCAGATTAAGATTAATTTCCTTTGCCGTGATTCGATTCTTGCTGCTCCTCTGTGCTTGGACCTTGTATTGT
TGAGTGACCTGGCTGCACGTGCAGGACGTTTTGGTATCCAACGTTTCTTGAGTTTCTTCTTGAAGAGTCCGATGCATGAT
TATACTGAAAACGAAATTCCTGTCAATCACCTCTTCCAGCAGTATGCTATTTTGAAAAATGCCATTCGTGAAATGGGTGG
TTATGAGGCCGATCAAGAAATCGACTAA

Upstream 100 bases:

>100_bases
AAAACTAGAAAAAGCATGGAAGTTTTCAAAAGAAGGTGTAACTTTGGCACAAATTATCTTAATCTCTGCTATGAGATGCA
ATTTTAACAAAGAAATTAGA

Downstream 100 bases:

>100_bases
TTTATAACAGGATTTTTTATTCGGGCGTGGATTGCGCGGGTTTTCACGGTTTTTCTTTTAAAGACCGTATCTATCCGTGA
AATCCACGTCTTATTTTTTA

Product: myo-inositol-1-phosphate synthase

Products: 1D-myo-inositol 3-phosphate

Alternate protein names: Myo-Inositol-1-Phosphate Synthase; Secreted Protein; Myo-Inositol Phosphate Synthase; InositoL-3-Phosphate Synthase

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEKMNVKPATGKLGVLCVGLGAVTSTFMTGVLMARKGLAKPVGSMTQYDKMRVGRGENKKYLHYGEIVPLANLNDIVFGA
WDVYPANAYESAVNAEVLKEKDINPVKDELEKIVPMKAAFDHNYASRLDGDNVKDCKNRWDMMEQLREDIRNFKVANNCD
RIVVLWAASTEIYVPVDEKIHGTLAALEQAMKDDDKAHIAPSMCYAYAALSEGCPFIMGAPNTTVDIPAMWELAEKTKMP
IAGKDFKTGQTLVKSGFAPIIGTRCLGLDGWFSTNILGNRDGLVLDEPANFHTKEVSKLSTLESILVPEDQPDLYTDYYH
KVRINYYPPRNDNKEGWDNIDIFGWMGYPMQIKINFLCRDSILAAPLCLDLVLLSDLAARAGRFGIQRFLSFFLKSPMHD
YTENEIPVNHLFQQYAILKNAIREMGGYEADQEID

Sequences:

>Translated_435_residues
MEKMNVKPATGKLGVLCVGLGAVTSTFMTGVLMARKGLAKPVGSMTQYDKMRVGRGENKKYLHYGEIVPLANLNDIVFGA
WDVYPANAYESAVNAEVLKEKDINPVKDELEKIVPMKAAFDHNYASRLDGDNVKDCKNRWDMMEQLREDIRNFKVANNCD
RIVVLWAASTEIYVPVDEKIHGTLAALEQAMKDDDKAHIAPSMCYAYAALSEGCPFIMGAPNTTVDIPAMWELAEKTKMP
IAGKDFKTGQTLVKSGFAPIIGTRCLGLDGWFSTNILGNRDGLVLDEPANFHTKEVSKLSTLESILVPEDQPDLYTDYYH
KVRINYYPPRNDNKEGWDNIDIFGWMGYPMQIKINFLCRDSILAAPLCLDLVLLSDLAARAGRFGIQRFLSFFLKSPMHD
YTENEIPVNHLFQQYAILKNAIREMGGYEADQEID
>Mature_435_residues
MEKMNVKPATGKLGVLCVGLGAVTSTFMTGVLMARKGLAKPVGSMTQYDKMRVGRGENKKYLHYGEIVPLANLNDIVFGA
WDVYPANAYESAVNAEVLKEKDINPVKDELEKIVPMKAAFDHNYASRLDGDNVKDCKNRWDMMEQLREDIRNFKVANNCD
RIVVLWAASTEIYVPVDEKIHGTLAALEQAMKDDDKAHIAPSMCYAYAALSEGCPFIMGAPNTTVDIPAMWELAEKTKMP
IAGKDFKTGQTLVKSGFAPIIGTRCLGLDGWFSTNILGNRDGLVLDEPANFHTKEVSKLSTLESILVPEDQPDLYTDYYH
KVRINYYPPRNDNKEGWDNIDIFGWMGYPMQIKINFLCRDSILAAPLCLDLVLLSDLAARAGRFGIQRFLSFFLKSPMHD
YTENEIPVNHLFQQYAILKNAIREMGGYEADQEID

Specific function: Unknown

COG id: COG1260

COG function: function code I; Myo-inositol-1-phosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705558, Length=448, Percent_Identity=30.1339285714286, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI283135176, Length=406, Percent_Identity=30.0492610837438, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI283135178, Length=304, Percent_Identity=32.5657894736842, Blast_Score=146, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25147617, Length=413, Percent_Identity=29.0556900726392, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322308, Length=468, Percent_Identity=30.5555555555556, Blast_Score=209, Evalue=6e-55,
Organism=Drosophila melanogaster, GI17137626, Length=447, Percent_Identity=29.3064876957494, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.5.1.4

Molecular weight: Translated: 48822; Mature: 48822

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKMNVKPATGKLGVLCVGLGAVTSTFMTGVLMARKGLAKPVGSMTQYDKMRVGRGENKK
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
YLHYGEIVPLANLNDIVFGAWDVYPANAYESAVNAEVLKEKDINPVKDELEKIVPMKAAF
EEEECCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHH
DHNYASRLDGDNVKDCKNRWDMMEQLREDIRNFKVANNCDRIVVLWAASTEIYVPVDEKI
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCEECCCCCEEEEEEECCCEEEEECCHHH
HGTLAALEQAMKDDDKAHIAPSMCYAYAALSEGCPFIMGAPNTTVDIPAMWELAEKTKMP
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCCCEEEECCCCCEECCHHHHHHHHHCCC
IAGKDFKTGQTLVKSGFAPIIGTRCLGLDGWFSTNILGNRDGLVLDEPANFHTKEVSKLS
CCCCCCCCHHHHHHCCCCHHHHHHEECCCCCEECCCCCCCCCEEEECCCCCCHHHHHHHH
TLESILVPEDQPDLYTDYYHKVRINYYPPRNDNKEGWDNIDIFGWMGYPMQIKINFLCRD
HHHHHHCCCCCCCHHHCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEECC
SILAAPLCLDLVLLSDLAARAGRFGIQRFLSFFLKSPMHDYTENEIPVNHLFQQYAILKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHH
AIREMGGYEADQEID
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MEKMNVKPATGKLGVLCVGLGAVTSTFMTGVLMARKGLAKPVGSMTQYDKMRVGRGENKK
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
YLHYGEIVPLANLNDIVFGAWDVYPANAYESAVNAEVLKEKDINPVKDELEKIVPMKAAF
EEEECCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHH
DHNYASRLDGDNVKDCKNRWDMMEQLREDIRNFKVANNCDRIVVLWAASTEIYVPVDEKI
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCEECCCCCEEEEEEECCCEEEEECCHHH
HGTLAALEQAMKDDDKAHIAPSMCYAYAALSEGCPFIMGAPNTTVDIPAMWELAEKTKMP
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCCCEEEECCCCCEECCHHHHHHHHHCCC
IAGKDFKTGQTLVKSGFAPIIGTRCLGLDGWFSTNILGNRDGLVLDEPANFHTKEVSKLS
CCCCCCCCHHHHHHCCCCHHHHHHEECCCCCEECCCCCCCCCEEEECCCCCCHHHHHHHH
TLESILVPEDQPDLYTDYYHKVRINYYPPRNDNKEGWDNIDIFGWMGYPMQIKINFLCRD
HHHHHHCCCCCCCHHHCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEECC
SILAAPLCLDLVLLSDLAARAGRFGIQRFLSFFLKSPMHDYTENEIPVNHLFQQYAILKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHH
AIREMGGYEADQEID
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glucose 6-phosphate

Specific reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA