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The map label for this gene is sdaA [H]

Identifier: 150004980

GI number: 150004980

Start: 3140535

End: 3141743

Strand: Reverse

Name: sdaA [H]

Synonym: BVU_2444

Alternate gene names: 150004980

Gene position: 3141743-3140535 (Counterclockwise)

Preceding gene: 150004981

Following gene: 150004975

Centisome position: 60.85

GC content: 48.14

Gene sequence:

>1209_bases
ATGAAATCTATCCGAGAACTATACCGCATCGGCACCGGTCCGTCCAGCAGTCATACTATGGGACCGCGCAAGGCTGCTGA
AATCTTCTTAGGAAAACATCCCGAAGCCAAAGCTTTTCAAGTTACTCTTTATGGAAGCCTCGCCGCTACCGGTAAAGGAC
ACATGACCGATGTAGCCATTTTAGATACATTGCAACCGCATGCGCCTACAGAAATTATCTGGAAAGCCCATGTCTTCTAT
CCGTTTCATCCCAATGGAATGACTTTCAAATCTTTGAATGAAAAAGGAAAGGTGACAGATGAATGGACTGTTTTCAGTGT
AGGCGGAGGTGCTCTAGCCGAAGAAGGACACGACAAAGGCTCAACTCCGGAAATCTATGATATGAACCGTATGAGTGAAA
TCCTCTACTGGTGTGAACGTACCGGGCGCAATTACTGGGAATACGTCCAGCAATGTGAAGACGAAGACATTTGGGACTAT
CTGGCAGAAGTATGGAAAACCATGAGAGAAGCCATTGAGCGTGGTTTGGATCAAGAAGGCGTATTACCCGGGCCACTCAA
TCTGCGCAGAAAAGCCTCCACTTACTATATTAAGGCAAAAGGTTATAAGGACAATCTGCGTTCCCGCGGGTTAGTATTCT
CATACGCTCTGGCAGTCAGTGAAGAAAACGCCTCAGGTGGCAAAATCGTCACAGCCCCTACTTGCGGATCATGCGGAGTG
GTTCCGGCTGTACTTTATCACTTGCAAAAAAGCCGTGACTTCAGCGATATGCGGATTTTAAGAGCACTGGCTACTGCCGG
ATTGATAGGAAATATAGTAAAACACAACGCCTCCATTTCCGGAGCCGAAGCCGGTTGCCAGGCAGAAGTAGGAGTGGCCT
GTTCAATGGCATCCGCCGCTGCCAGCCAATTATTCGGAGGTAGCCCGGCCCAGATAGAGTATGCAGCCGAAATGGGCTTG
GAGCATCACTTGGGAATGACTTGCGATCCGGTATGCGGATTGGTACAAATCCCTTGTATCGAAAGAAATGCCTATGCAGC
AGCCCGAGCTCTTGATGCCAATATCTATTCTGCCTTTACAGACGGTAATCACCGTGTATCCTTTGACAAAGTGGTGGAAG
TAATGAAACAGACCGGTCATGACCTTCCTTCCTTATATAAGGAAACCAGCGAAGGCGGTCTGGCAAAGGATTACGAGCCG
ATGGATTAA

Upstream 100 bases:

>100_bases
TTTCCTATTTGTCAAGAGAGTTTTTCTTTTCCTTTTTTGCTACTTTCCCCCTTTTATTTTATACCTTTGTTCCTCATAAT
AACTAACCTTATAAAACGAA

Downstream 100 bases:

>100_bases
TAACAGGGCAAAGACCGAGAACTGTATTTATAATACATAAGAGGGTGAATCAAAATTCGTTGCAACTATCTTTTTCAACG
CTGATAATAAAAAGATAGTT

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKSIRELYRIGTGPSSSHTMGPRKAAEIFLGKHPEAKAFQVTLYGSLAATGKGHMTDVAILDTLQPHAPTEIIWKAHVFY
PFHPNGMTFKSLNEKGKVTDEWTVFSVGGGALAEEGHDKGSTPEIYDMNRMSEILYWCERTGRNYWEYVQQCEDEDIWDY
LAEVWKTMREAIERGLDQEGVLPGPLNLRRKASTYYIKAKGYKDNLRSRGLVFSYALAVSEENASGGKIVTAPTCGSCGV
VPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKHNASISGAEAGCQAEVGVACSMASAAASQLFGGSPAQIEYAAEMGL
EHHLGMTCDPVCGLVQIPCIERNAYAAARALDANIYSAFTDGNHRVSFDKVVEVMKQTGHDLPSLYKETSEGGLAKDYEP
MD

Sequences:

>Translated_402_residues
MKSIRELYRIGTGPSSSHTMGPRKAAEIFLGKHPEAKAFQVTLYGSLAATGKGHMTDVAILDTLQPHAPTEIIWKAHVFY
PFHPNGMTFKSLNEKGKVTDEWTVFSVGGGALAEEGHDKGSTPEIYDMNRMSEILYWCERTGRNYWEYVQQCEDEDIWDY
LAEVWKTMREAIERGLDQEGVLPGPLNLRRKASTYYIKAKGYKDNLRSRGLVFSYALAVSEENASGGKIVTAPTCGSCGV
VPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKHNASISGAEAGCQAEVGVACSMASAAASQLFGGSPAQIEYAAEMGL
EHHLGMTCDPVCGLVQIPCIERNAYAAARALDANIYSAFTDGNHRVSFDKVVEVMKQTGHDLPSLYKETSEGGLAKDYEP
MD
>Mature_402_residues
MKSIRELYRIGTGPSSSHTMGPRKAAEIFLGKHPEAKAFQVTLYGSLAATGKGHMTDVAILDTLQPHAPTEIIWKAHVFY
PFHPNGMTFKSLNEKGKVTDEWTVFSVGGGALAEEGHDKGSTPEIYDMNRMSEILYWCERTGRNYWEYVQQCEDEDIWDY
LAEVWKTMREAIERGLDQEGVLPGPLNLRRKASTYYIKAKGYKDNLRSRGLVFSYALAVSEENASGGKIVTAPTCGSCGV
VPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKHNASISGAEAGCQAEVGVACSMASAAASQLFGGSPAQIEYAAEMGL
EHHLGMTCDPVCGLVQIPCIERNAYAAARALDANIYSAFTDGNHRVSFDKVVEVMKQTGHDLPSLYKETSEGGLAKDYEP
MD

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=450, Percent_Identity=41.3333333333333, Blast_Score=304, Evalue=7e-84,
Organism=Escherichia coli, GI1788116, Length=451, Percent_Identity=40.5764966740577, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1789161, Length=449, Percent_Identity=39.4209354120267, Blast_Score=292, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 43965; Mature: 43965

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIRELYRIGTGPSSSHTMGPRKAAEIFLGKHPEAKAFQVTLYGSLAATGKGHMTDVAI
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECEEECCCCCCCHHHH
LDTLQPHAPTEIIWKAHVFYPFHPNGMTFKSLNEKGKVTDEWTVFSVGGGALAEEGHDKG
HHCCCCCCCCEEEEEEEEEEEECCCCCCHHCCCCCCCCCCCEEEEEECCCHHHCCCCCCC
STPEIYDMNRMSEILYWCERTGRNYWEYVQQCEDEDIWDYLAEVWKTMREAIERGLDQEG
CCCCEECHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VLPGPLNLRRKASTYYIKAKGYKDNLRSRGLVFSYALAVSEENASGGKIVTAPTCGSCGV
CCCCCCCCCCCCCEEEEEECCCHHHHHCCCEEEEEEEEEECCCCCCCEEEECCCCCCCCH
VPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKHNASISGAEAGCQAEVGVACSMASAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
ASQLFGGSPAQIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARALDANIYSAFT
HHHHCCCCCCCCHHHHHCCHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHCCHHHEEEC
DGNHRVSFDKVVEVMKQTGHDLPSLYKETSEGGLAKDYEPMD
CCCCEECHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKSIRELYRIGTGPSSSHTMGPRKAAEIFLGKHPEAKAFQVTLYGSLAATGKGHMTDVAI
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECEEECCCCCCCHHHH
LDTLQPHAPTEIIWKAHVFYPFHPNGMTFKSLNEKGKVTDEWTVFSVGGGALAEEGHDKG
HHCCCCCCCCEEEEEEEEEEEECCCCCCHHCCCCCCCCCCCEEEEEECCCHHHCCCCCCC
STPEIYDMNRMSEILYWCERTGRNYWEYVQQCEDEDIWDYLAEVWKTMREAIERGLDQEG
CCCCEECHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VLPGPLNLRRKASTYYIKAKGYKDNLRSRGLVFSYALAVSEENASGGKIVTAPTCGSCGV
CCCCCCCCCCCCCEEEEEECCCHHHHHCCCEEEEEEEEEECCCCCCCEEEECCCCCCCCH
VPAVLYHLQKSRDFSDMRILRALATAGLIGNIVKHNASISGAEAGCQAEVGVACSMASAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
ASQLFGGSPAQIEYAAEMGLEHHLGMTCDPVCGLVQIPCIERNAYAAARALDANIYSAFT
HHHHCCCCCCCCHHHHHCCHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHCCHHHEEEC
DGNHRVSFDKVVEVMKQTGHDLPSLYKETSEGGLAKDYEPMD
CCCCEECHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]