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The map label for this gene is atoC [H]

Identifier: 150004891

GI number: 150004891

Start: 3033128

End: 3034483

Strand: Direct

Name: atoC [H]

Synonym: BVU_2354

Alternate gene names: 150004891

Gene position: 3033128-3034483 (Clockwise)

Preceding gene: 150004890

Following gene: 150004892

Centisome position: 58.75

GC content: 45.43

Gene sequence:

>1356_bases
ATGATATTAATTATAGACGATGACAGTGCCATTCGTTCTTCTCTGAGCTTTATGCTGAAAAGGGCGAAATATGATGTGCA
GGCCGTACCAGGTCCCAAAGAGGCTATTGAAATAGTCCGTTCGGTTGCACCCCAGTTAATCTTGATGGATATGAACTTCA
CCCTGTCCACCAGTGGTGAAGAAGGATTGACGCTTTTGAAACAGGTCAAAGTGTTCCGGCCCGATGTTCCCGTTATATTG
ATGACGGCATGGGGAAGTATCCAGCTTGCCGTGCAAGGGATGCAGGCAGGTGCATTCGACTTTATTACCAAACCTTGGAA
CAACGTAGCGTTGATGCAAAGGATAGAAACTGCTTTGGAACTGACTTCACAAGATAAGAAAGCAGCGGTTCCGGTGGAAG
ATAATGACGGCTTCAACCGTAGTCATATCATTGGAAAGAGTAAGGCACTGATGGATGTGCTGGCCACGATCAAGCGGATA
GCGCGTACCAACGCATCGGTCTTGATTACCGGTGAAAGTGGTACAGGTAAGGAGTTGATAGCCGAAGCGGTGCATTTGAA
CAGTTCCCGTAGCAAGAAACCTTTTGTGAAAGTGAATTTGGGAGGTATTTCTCATACTTTGTTCGAGAGTGAAATGTTCG
GTCATAAGAAAGGTGCGTTTACGGATGCCACAGCCGACAGGGTAGGACGTTTTGAACTGGCTGATAAGGGTACGATTTTC
TTGGATGAGATTGGCGATTTGGATTTAAGCTGTCAGGTGAAACTGCTTCGCGTGTTACAAGAGCAGACTTTTGAAGTTTT
GGGCGACAGCCGTCCCCGTAAAGTCGATATCCGTGTGGTCAGTGCGACGAATGCCGATTTACGGCAGATGGTGCAGGAAC
ACACCTTCCGCGAGGATTTGTTCTATCGTATTAATTTAATTACGGTGCATCTTCCGGCATTACGCGAACGCCGTGAGGAT
ATTCCGTTATTGGTCCGTCATTTCGCCGACAAACAATGTGAATCGAACGGTCTTCCCAAAGTGGAATTTACTTCTGAAGC
GATGGATTATTTGAGCCGTTTGCCTTATCCGGGTAATATCCGTGAATTAAAGAATTTGGTGGAACGTACCTTGCTGGTCA
GTGGAAAGGAAATATTGACTGCGGATGATTTTAAATCACAATACCAGCATCCTATAGAACAGAAGATGACAACGAATCTG
CAAGGCATGACCTTGGAGGAGATAGAAAAGCAGACTATTCTGCAAACGCTTGAAAAGTATAACAATAATATGTCACAGGT
TGCCATAGCCTTAGGAATCAGCCGGGCCGCTCTTTATCGCCGTTTGGAGAAATACAATATACAAGTGAATGATTAG

Upstream 100 bases:

>100_bases
ATTATCAAACAATAGGATTTTTACTATTCAATTCTGTTTGAATATAAAATGGGGTTGTCTTTGTACTTATTAAAATAATA
ATTTCTACATTTGCAGTATT

Downstream 100 bases:

>100_bases
CAAAAACGGAACCGGATAAAATATGAAACTGAAATTCTTGTTCTTCTTTTTAGCATTACTGTTGACAGCAGTATGGACTA
TCCTGCTCGTTCTTACATTG

Product: two-component system response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MILIIDDDSAIRSSLSFMLKRAKYDVQAVPGPKEAIEIVRSVAPQLILMDMNFTLSTSGEEGLTLLKQVKVFRPDVPVIL
MTAWGSIQLAVQGMQAGAFDFITKPWNNVALMQRIETALELTSQDKKAAVPVEDNDGFNRSHIIGKSKALMDVLATIKRI
ARTNASVLITGESGTGKELIAEAVHLNSSRSKKPFVKVNLGGISHTLFESEMFGHKKGAFTDATADRVGRFELADKGTIF
LDEIGDLDLSCQVKLLRVLQEQTFEVLGDSRPRKVDIRVVSATNADLRQMVQEHTFREDLFYRINLITVHLPALRERRED
IPLLVRHFADKQCESNGLPKVEFTSEAMDYLSRLPYPGNIRELKNLVERTLLVSGKEILTADDFKSQYQHPIEQKMTTNL
QGMTLEEIEKQTILQTLEKYNNNMSQVAIALGISRAALYRRLEKYNIQVND

Sequences:

>Translated_451_residues
MILIIDDDSAIRSSLSFMLKRAKYDVQAVPGPKEAIEIVRSVAPQLILMDMNFTLSTSGEEGLTLLKQVKVFRPDVPVIL
MTAWGSIQLAVQGMQAGAFDFITKPWNNVALMQRIETALELTSQDKKAAVPVEDNDGFNRSHIIGKSKALMDVLATIKRI
ARTNASVLITGESGTGKELIAEAVHLNSSRSKKPFVKVNLGGISHTLFESEMFGHKKGAFTDATADRVGRFELADKGTIF
LDEIGDLDLSCQVKLLRVLQEQTFEVLGDSRPRKVDIRVVSATNADLRQMVQEHTFREDLFYRINLITVHLPALRERRED
IPLLVRHFADKQCESNGLPKVEFTSEAMDYLSRLPYPGNIRELKNLVERTLLVSGKEILTADDFKSQYQHPIEQKMTTNL
QGMTLEEIEKQTILQTLEKYNNNMSQVAIALGISRAALYRRLEKYNIQVND
>Mature_451_residues
MILIIDDDSAIRSSLSFMLKRAKYDVQAVPGPKEAIEIVRSVAPQLILMDMNFTLSTSGEEGLTLLKQVKVFRPDVPVIL
MTAWGSIQLAVQGMQAGAFDFITKPWNNVALMQRIETALELTSQDKKAAVPVEDNDGFNRSHIIGKSKALMDVLATIKRI
ARTNASVLITGESGTGKELIAEAVHLNSSRSKKPFVKVNLGGISHTLFESEMFGHKKGAFTDATADRVGRFELADKGTIF
LDEIGDLDLSCQVKLLRVLQEQTFEVLGDSRPRKVDIRVVSATNADLRQMVQEHTFREDLFYRINLITVHLPALRERRED
IPLLVRHFADKQCESNGLPKVEFTSEAMDYLSRLPYPGNIRELKNLVERTLLVSGKEILTADDFKSQYQHPIEQKMTTNL
QGMTLEEIEKQTILQTLEKYNNNMSQVAIALGISRAALYRRLEKYNIQVND

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=458, Percent_Identity=40.6113537117904, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=39.8648648648649, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1790299, Length=475, Percent_Identity=38.7368421052632, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1788905, Length=450, Percent_Identity=34.6666666666667, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=43.4782608695652, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1789087, Length=311, Percent_Identity=42.7652733118971, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=40.7523510971787, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI87082152, Length=333, Percent_Identity=36.6366366366366, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=39.2523364485981, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1786524, Length=314, Percent_Identity=37.5796178343949, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1787583, Length=326, Percent_Identity=34.6625766871166, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI87081858, Length=296, Percent_Identity=28.0405405405405, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789828, Length=251, Percent_Identity=35.8565737051793, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50706; Mature: 50706

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIIDDDSAIRSSLSFMLKRAKYDVQAVPGPKEAIEIVRSVAPQLILMDMNFTLSTSGE
CEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCEEEECCCC
EGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITKPWNNVALMQRIETALE
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHH
LTSQDKKAAVPVEDNDGFNRSHIIGKSKALMDVLATIKRIARTNASVLITGESGTGKELI
HHCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
AEAVHLNSSRSKKPFVKVNLGGISHTLFESEMFGHKKGAFTDATADRVGRFELADKGTIF
HHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCEEECCCCCEE
LDEIGDLDLSCQVKLLRVLQEQTFEVLGDSRPRKVDIRVVSATNADLRQMVQEHTFREDL
EECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
FYRINLITVHLPALRERREDIPLLVRHFADKQCESNGLPKVEFTSEAMDYLSRLPYPGNI
EEEEEEEEEECHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCH
RELKNLVERTLLVSGKEILTADDFKSQYQHPIEQKMTTNLQGMTLEEIEKQTILQTLEKY
HHHHHHHHHHHHHCCCHHEECHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
NNNMSQVAIALGISRAALYRRLEKYNIQVND
CCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MILIIDDDSAIRSSLSFMLKRAKYDVQAVPGPKEAIEIVRSVAPQLILMDMNFTLSTSGE
CEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCEEEECCCC
EGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITKPWNNVALMQRIETALE
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHH
LTSQDKKAAVPVEDNDGFNRSHIIGKSKALMDVLATIKRIARTNASVLITGESGTGKELI
HHCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
AEAVHLNSSRSKKPFVKVNLGGISHTLFESEMFGHKKGAFTDATADRVGRFELADKGTIF
HHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCEEECCCCCEE
LDEIGDLDLSCQVKLLRVLQEQTFEVLGDSRPRKVDIRVVSATNADLRQMVQEHTFREDL
EECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
FYRINLITVHLPALRERREDIPLLVRHFADKQCESNGLPKVEFTSEAMDYLSRLPYPGNI
EEEEEEEEEECHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCH
RELKNLVERTLLVSGKEILTADDFKSQYQHPIEQKMTTNLQGMTLEEIEKQTILQTLEKY
HHHHHHHHHHHHHCCCHHEECHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
NNNMSQVAIALGISRAALYRRLEKYNIQVND
CCCHHHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]