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The map label for this gene is ntrY [H]

Identifier: 150004892

GI number: 150004892

Start: 3034506

End: 3035801

Strand: Direct

Name: ntrY [H]

Synonym: BVU_2355

Alternate gene names: 150004892

Gene position: 3034506-3035801 (Clockwise)

Preceding gene: 150004891

Following gene: 150004896

Centisome position: 58.77

GC content: 45.37

Gene sequence:

>1296_bases
ATGAAACTGAAATTCTTGTTCTTCTTTTTAGCATTACTGTTGACAGCAGTATGGACTATCCTGCTCGTTCTTACATTGAA
GGAACGCGGTGCGCTGTTTTATATAGGAGAGGGAGTCATTACATTCAGTCTTGTGTTTCTGGTTTATTTCTACCGCAAAG
TCGTGAAACCGCTTGATATCATCGGCAACGGTATGGAACTTCTTCGTGAGCAGGATTTCAGCAGTAGGCTGACTCCTGTC
GGACAAAAGGAAGCCGACCGCATTGTGTTGGTTTTCAACCGCATGATGGAGCAGTTGAAAGACGAGCGTCTCCGGTTGCG
TGAGCAGAATCATTTTCTTGACCTGCTGGTCAGTGCTTCTCCTATGGGAGTTGTCATACTGACTCTGGACGGACATATTT
CCATGCTGAATGCGGCAGCTCTTCGTTTTTTGGATTATTCTTCGTCAGAGGAAGTCAGAGGCCGATTGCTGTGCGAGTTG
GCTTCCCCTTTGGCCGAAGAAATAGAACGTATTCCCAAAGATACTACGGAAACAATTCGTCTGAGTGACTCCATGATTTA
CCGCTGTTCCCGGCTTTCTTTTGTTGACAGAGGCTTTTCTCATCCGTTTATTCTGGTGGAAAGTCTGACTTCCGAGGTGG
TGAAAGCAGAGAAAAAGGCATACGAAAAAGTGATCCGTATGATAGCACATGAGGTGAATAATACGACTGCGGGCATTACC
TCTACTCTTGATACGGTGGATGGTGCCTTGGAATGTATGGAGGATACGGAAGACTTGCGCGAAGTGATGAAAGTCTGCAT
AGAGCGTTGCTACAGCATGAGCCGTTTTATCACGAATTTCGCCAATGTGGTGAAGATTCCCGAGCCTCAATTACAATCAG
TGGACTTGAATGACCGCGTGGCCGCTTGCAAGACATTTATGGAAACGGTTTGCCGTAACCGCAAGATTACGCTGCATCTT
AATTTATGTAAAGAGAATCCCGAAGTGATGATGGATACTTCCTTGTTTGAGCAAGTATTGGTCAACATTATCAAGAATGC
GGCTGAAAGTATCGGGGAAACAGGAGATATCTTTATCCGTACTTCCGTATCACCTACGATGTTGGAAATTGCTGATACCG
GTGCCGGTATCAGTAAAGAGGTGGAAACCAAGCTGTTCAGTCCTTTCTTCTCCACCAAGCCTAACGGACAGGGTATCGGT
CTTATTTTTATCCGTGAAGTTTTGATAAAACATGGGTGTACTTTCTCTCTTCGTACCTATCCGGATAAACTGACCCGTTT
CCGTATCCGTTTCTGA

Upstream 100 bases:

>100_bases
GTTGCCATAGCCTTAGGAATCAGCCGGGCCGCTCTTTATCGCCGTTTGGAGAAATACAATATACAAGTGAATGATTAGCA
AAAACGGAACCGGATAAAAT

Downstream 100 bases:

>100_bases
TGATTTTCTACCACTTTACCACGCTGCGATGCTTCCGTAAGGAAGTGCAAAGGGAGGGGGTATAGTAAACGTCTTTCGGA
TGTTTCTTTTTGTGCTGTTG

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKLKFLFFFLALLLTAVWTILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSSRLTPV
GQKEADRIVLVFNRMMEQLKDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSSEEVRGRLLCEL
ASPLAEEIERIPKDTTETIRLSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGIT
STLDTVDGALECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITLHL
NLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIG
LIFIREVLIKHGCTFSLRTYPDKLTRFRIRF

Sequences:

>Translated_431_residues
MKLKFLFFFLALLLTAVWTILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSSRLTPV
GQKEADRIVLVFNRMMEQLKDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSSEEVRGRLLCEL
ASPLAEEIERIPKDTTETIRLSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGIT
STLDTVDGALECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITLHL
NLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIG
LIFIREVLIKHGCTFSLRTYPDKLTRFRIRF
>Mature_431_residues
MKLKFLFFFLALLLTAVWTILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDIIGNGMELLREQDFSSRLTPV
GQKEADRIVLVFNRMMEQLKDERLRLREQNHFLDLLVSASPMGVVILTLDGHISMLNAAALRFLDYSSSEEVRGRLLCEL
ASPLAEEIERIPKDTTETIRLSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGIT
STLDTVDGALECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRVAACKTFMETVCRNRKITLHL
NLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIRTSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIG
LIFIREVLIKHGCTFSLRTYPDKLTRFRIRF

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=400, Percent_Identity=24.75, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=26.1061946902655, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790300, Length=227, Percent_Identity=23.3480176211454, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49038; Mature: 49038

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKFLFFFLALLLTAVWTILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
IGNGMELLREQDFSSRLTPVGQKEADRIVLVFNRMMEQLKDERLRLREQNHFLDLLVSAS
HCCCHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMGVVILTLDGHISMLNAAALRFLDYSSSEEVRGRLLCELASPLAEEIERIPKDTTETIR
CCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEE
LSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGIT
ECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
STLDTVDGALECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHH
AACKTFMETVCRNRKITLHLNLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIR
HHHHHHHHHHHCCCEEEEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGLIFIREVLIKHGCTFSLRTY
ECCCCHHEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHCCCCEEECCC
PDKLTRFRIRF
HHHHHEEEECC
>Mature Secondary Structure
MKLKFLFFFLALLLTAVWTILLVLTLKERGALFYIGEGVITFSLVFLVYFYRKVVKPLDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
IGNGMELLREQDFSSRLTPVGQKEADRIVLVFNRMMEQLKDERLRLREQNHFLDLLVSAS
HCCCHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMGVVILTLDGHISMLNAAALRFLDYSSSEEVRGRLLCELASPLAEEIERIPKDTTETIR
CCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEE
LSDSMIYRCSRLSFVDRGFSHPFILVESLTSEVVKAEKKAYEKVIRMIAHEVNNTTAGIT
ECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
STLDTVDGALECMEDTEDLREVMKVCIERCYSMSRFITNFANVVKIPEPQLQSVDLNDRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHH
AACKTFMETVCRNRKITLHLNLCKENPEVMMDTSLFEQVLVNIIKNAAESIGETGDIFIR
HHHHHHHHHHHCCCEEEEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TSVSPTMLEIADTGAGISKEVETKLFSPFFSTKPNGQGIGLIFIREVLIKHGCTFSLRTY
ECCCCHHEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHCCCCEEECCC
PDKLTRFRIRF
HHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]