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The map label for this gene is zraR [H]

Identifier: 150004715

GI number: 150004715

Start: 2812586

End: 2813881

Strand: Direct

Name: zraR [H]

Synonym: BVU_2176

Alternate gene names: 150004715

Gene position: 2812586-2813881 (Clockwise)

Preceding gene: 150004714

Following gene: 150004716

Centisome position: 54.47

GC content: 58.49

Gene sequence:

>1296_bases
ATGGAGACAATACTCATAGTGGAGGATGACCGTACATACGCACGCGCCACCGCCAACTGGCTGGCTCGAAACGGCATGGA
CACCCGTTACGTGCTCTCGGCGGACGCCGCAAAGGAGTTTCTGGGCAGCCATGAAGCGGCTCTGGTTCTCTCGGATTTCC
GTCTGGGTGACTGCAACGGCGTGGAACTGCTCGAATGGATGAGGGCTCACGGCTACCGTATGCCCTTTCTTGTCATGACG
GGTTATGGGGACATATCCGGTGCCGTGGAGGCCGTGAAGAAAGGGGCCGACAATTATCTGCCCAAGCCCGTGCAAACGGA
AAAGGTGCTCGGTGTCATCCGCGGACTGTTGGGGCGTGGGAGGAAAAGGACGATGGAACAGAACTTCTACATCTGCAAAA
GCCCGCCGGCTGTAAGACTTCAGGAGATGGTACGTCTGGTGGCTCCTGCGGACGGTCTGTCCGTGCTGATACGCGGGGCG
TCGGGTACGGGCAAGGAGCGGGTGGCACGGCAGATACACGCTTTCAGCAAGCGTTCGGCCGCCCCTTTCGTAGCAGTGGA
CTGCGGAGCCCTTCCACGGGAACTGGCCGCATCGGAACTGTTCGGGCATAAGAAGGGGGCTTTTACCGGAGCGGTGGAGG
ACAAGAGCGGCGTGTTCGCTGCCGCCGAGCACGGGACATTGTTTCTGGATGAGATCGGCAACCTGAATATGGAGACGCAG
GTACAACTGTTGCGCGCCCTGCAGGAGAAGCGCTACAGACTTGTCGGTGGAACGGAGGAGATGCATGCGGATGTCCGGCT
GTTGGCGGCCACCAACGAGGACCTGGAACAGGCGATAAGCGAGGGACGGTTCAGGGAGGACCTTTTCCACCGGCTGAACG
AGTTCCCGCTCCATGTTCCGCCTCTGAAGGACTGCGGGGAGGACATCATGCCGCTGGCCGGATTCCTCCTCTCTTCCGCG
AATGAGGAACTGGAAAAGGAAATAAGGGGATTTGACCGGGACGTCAGGGAGGCTTTCGTGTCCTATCCGTGGCCCGGCAA
TATCCGTGAGCTGAAAAATGTGGTGAGACGTGCATGTGTGCTGGCGCAGGGGGACTGGATCACTCTCAAGGAGATCAGCC
TTCCGGTGGATGTATCCCCCTCGGATAATTACAGACTGGATATGGAGCGGACGGAGCAGGAGGCGATACAGAAGGCGCTG
GAAATTACAGGTAATGACCGGAAAGCAGCCGCACGGCTGCTGGGCATATCCCGGAGCACGCTTTATCTGAAATTGAAAAA
GTACGGCCTGATTTGA

Upstream 100 bases:

>100_bases
CCTGAAAAATGGGCCGGTATGTCGGACGAGCGGATCGGAAGGTTGGTCAGGGCTGTAGAGAATGCTGTAAGGAAGGCCGT
AACATTAAAGGAGAAAATGA

Downstream 100 bases:

>100_bases
AACTGTCCACATTTCTGGACACACCGTGTCCGACGGGAGATTATGGACATGGACACACAATTATACACTGATATTATAAC
ATTCACGTTTTCAAAAGATT

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
METILIVEDDRTYARATANWLARNGMDTRYVLSADAAKEFLGSHEAALVLSDFRLGDCNGVELLEWMRAHGYRMPFLVMT
GYGDISGAVEAVKKGADNYLPKPVQTEKVLGVIRGLLGRGRKRTMEQNFYICKSPPAVRLQEMVRLVAPADGLSVLIRGA
SGTGKERVARQIHAFSKRSAAPFVAVDCGALPRELAASELFGHKKGAFTGAVEDKSGVFAAAEHGTLFLDEIGNLNMETQ
VQLLRALQEKRYRLVGGTEEMHADVRLLAATNEDLEQAISEGRFREDLFHRLNEFPLHVPPLKDCGEDIMPLAGFLLSSA
NEELEKEIRGFDRDVREAFVSYPWPGNIRELKNVVRRACVLAQGDWITLKEISLPVDVSPSDNYRLDMERTEQEAIQKAL
EITGNDRKAAARLLGISRSTLYLKLKKYGLI

Sequences:

>Translated_431_residues
METILIVEDDRTYARATANWLARNGMDTRYVLSADAAKEFLGSHEAALVLSDFRLGDCNGVELLEWMRAHGYRMPFLVMT
GYGDISGAVEAVKKGADNYLPKPVQTEKVLGVIRGLLGRGRKRTMEQNFYICKSPPAVRLQEMVRLVAPADGLSVLIRGA
SGTGKERVARQIHAFSKRSAAPFVAVDCGALPRELAASELFGHKKGAFTGAVEDKSGVFAAAEHGTLFLDEIGNLNMETQ
VQLLRALQEKRYRLVGGTEEMHADVRLLAATNEDLEQAISEGRFREDLFHRLNEFPLHVPPLKDCGEDIMPLAGFLLSSA
NEELEKEIRGFDRDVREAFVSYPWPGNIRELKNVVRRACVLAQGDWITLKEISLPVDVSPSDNYRLDMERTEQEAIQKAL
EITGNDRKAAARLLGISRSTLYLKLKKYGLI
>Mature_431_residues
METILIVEDDRTYARATANWLARNGMDTRYVLSADAAKEFLGSHEAALVLSDFRLGDCNGVELLEWMRAHGYRMPFLVMT
GYGDISGAVEAVKKGADNYLPKPVQTEKVLGVIRGLLGRGRKRTMEQNFYICKSPPAVRLQEMVRLVAPADGLSVLIRGA
SGTGKERVARQIHAFSKRSAAPFVAVDCGALPRELAASELFGHKKGAFTGAVEDKSGVFAAAEHGTLFLDEIGNLNMETQ
VQLLRALQEKRYRLVGGTEEMHADVRLLAATNEDLEQAISEGRFREDLFHRLNEFPLHVPPLKDCGEDIMPLAGFLLSSA
NEELEKEIRGFDRDVREAFVSYPWPGNIRELKNVVRRACVLAQGDWITLKEISLPVDVSPSDNYRLDMERTEQEAIQKAL
EITGNDRKAAARLLGISRSTLYLKLKKYGLI

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=436, Percent_Identity=41.2844036697248, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=37.4722838137472, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1788905, Length=438, Percent_Identity=36.7579908675799, Blast_Score=274, Evalue=9e-75,
Organism=Escherichia coli, GI1790299, Length=470, Percent_Identity=34.468085106383, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI87082152, Length=327, Percent_Identity=41.8960244648318, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87082117, Length=310, Percent_Identity=40.3225806451613, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1789233, Length=312, Percent_Identity=40.3846153846154, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1789087, Length=306, Percent_Identity=38.562091503268, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=37.3417721518987, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87081872, Length=311, Percent_Identity=38.5852090032154, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1787583, Length=299, Percent_Identity=35.7859531772575, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1789828, Length=250, Percent_Identity=36.4, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081858, Length=291, Percent_Identity=28.8659793814433, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47950; Mature: 47950

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METILIVEDDRTYARATANWLARNGMDTRYVLSADAAKEFLGSHEAALVLSDFRLGDCNG
CCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCCCC
VELLEWMRAHGYRMPFLVMTGYGDISGAVEAVKKGADNYLPKPVQTEKVLGVIRGLLGRG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
RKRTMEQNFYICKSPPAVRLQEMVRLVAPADGLSVLIRGASGTGKERVARQIHAFSKRSA
HHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
APFVAVDCGALPRELAASELFGHKKGAFTGAVEDKSGVFAAAEHGTLFLDEIGNLNMETQ
CCEEEEECCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEECCCCEEEEEHHCCCCHHHH
VQLLRALQEKRYRLVGGTEEMHADVRLLAATNEDLEQAISEGRFREDLFHRLNEFPLHVP
HHHHHHHHHCCEEECCCCHHHHCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PLKDCGEDIMPLAGFLLSSANEELEKEIRGFDRDVREAFVSYPWPGNIRELKNVVRRACV
CHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LAQGDWITLKEISLPVDVSPSDNYRLDMERTEQEAIQKALEITGNDRKAAARLLGISRST
HCCCCEEEEEEEECCEECCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCE
LYLKLKKYGLI
EEEEEHHHCCC
>Mature Secondary Structure
METILIVEDDRTYARATANWLARNGMDTRYVLSADAAKEFLGSHEAALVLSDFRLGDCNG
CCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCCCC
VELLEWMRAHGYRMPFLVMTGYGDISGAVEAVKKGADNYLPKPVQTEKVLGVIRGLLGRG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
RKRTMEQNFYICKSPPAVRLQEMVRLVAPADGLSVLIRGASGTGKERVARQIHAFSKRSA
HHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
APFVAVDCGALPRELAASELFGHKKGAFTGAVEDKSGVFAAAEHGTLFLDEIGNLNMETQ
CCEEEEECCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEECCCCEEEEEHHCCCCHHHH
VQLLRALQEKRYRLVGGTEEMHADVRLLAATNEDLEQAISEGRFREDLFHRLNEFPLHVP
HHHHHHHHHCCEEECCCCHHHHCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PLKDCGEDIMPLAGFLLSSANEELEKEIRGFDRDVREAFVSYPWPGNIRELKNVVRRACV
CHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LAQGDWITLKEISLPVDVSPSDNYRLDMERTEQEAIQKALEITGNDRKAAARLLGISRST
HCCCCEEEEEEEECCEECCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCE
LYLKLKKYGLI
EEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]