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The map label for this gene is luxQ [H]

Identifier: 150004714

GI number: 150004714

Start: 2810248

End: 2812614

Strand: Direct

Name: luxQ [H]

Synonym: BVU_2175

Alternate gene names: 150004714

Gene position: 2810248-2812614 (Clockwise)

Preceding gene: 150004713

Following gene: 150004715

Centisome position: 54.43

GC content: 56.32

Gene sequence:

>2367_bases
ATGAGATCTTTTCTTTCCATACTCCAGTTGAAGATAGCCGGCGGATACATTCTGCTGCTGGCATTGCTCTGTGCTGTGGT
TTTTCTTGTCCGGCTGGAGCATGGAAAGATGGAGGAACTGGATTCCAGGGAACATTCGACCAATATGAGAAGGAAGGCCG
TCAACCGGACCTTTGAAAAACTGCTGGAATTCTCCTTCCATGACCATTTCCTGCTGATGCAGGACAGTGCGGATATCCGT
GAATGCGGGAACAGTTGTGCGGCGGCTCTGGACGCCTTGAACGGACTGAAACCTTATTATGCGGCAGAACAGCATCCGGC
CATAGACACCGTATCCATGCTCCTGCTGGAAAAGGAGCGGCTGCTGTATGAGTTGACGAACACCCTTTCCGGTTTTCCCC
GTGCGGACAGCCTTCTTCTGAGAAAGGCTCCCGGAATCGTGCGGCAGGTGCGGGATGCCGGACAGCCGGATACACCGTCG
GCAAAGAAAGGCCGGGGCCTTCTCAATGTTCTTATAGGAGGCAGGAACAAGAAGTCCGCTTATGCCAATCGGAAGGAGAA
GGAGATGCGGAACCGAAAAAGACAGTCCTCCGTAAACGGAGAGTTCATCCGGCTGCAAAAGGACATGTACAGCCAGTATG
CTGACTACCGGAAAAGACTGGAGGCCTGCTCGGACAGCCTGCGGTGCCGCAACCGGGAACTGGACGCACGTATCAGCGGC
CTGATACATGATTTCGAACGGGCAGCCGATATGCAATATACGGAGGATATGGAAGAAACGGCGGCATTGAGAAGGCAGTC
GTTCCGTATCATCCTTTCTATAGCCGTCATTTCCGTTCTTCTGATAATCCTGCTCTATCTTCTTATCCATGCCGACATCA
GAAAGAGGCAGAAGTACCGGATGACACTTGAGGCCGCCTGCTCCCGGAATGAAGAGCTGCTGGTGTCCCGCCGTAACCTG
ATGCTGTCGGTGAGCCATGACCTGCGGGCGCCTCTCGGTACGGTCTGCGAGTTTGCGGAACTGATGCAGCATGAGAAGGA
TGCCGGGCTTGTAAGGGAGTTCGCCGCCAACATCCTGCACGCCTCCCGTCATGTCATCGGACTGGCCAACAACCTGCAGC
ACTACTACAGGCTGGAAGAGGGTAAGGAACAGCCGGAGAATGCCGTATTCCATCTGGGGCAGACTATCGGGAATGCCGTG
CGTGTCTATCTTCCCTCCGCTGAAAAGAAGGGGCTCGGACTGACAACGGAAATAAAATCGTGTGATGTGCTTGTCAGGGG
CGATTCCGGACGGCTTGTCCGGATTCTCGGCAACCTGCTGTCAAACGCGGTCAAGTTCACGCGTACCGGTTACATCCATG
TGGGGGCCTCGTACGGAAACGGCAGGCTCCTGCTGTTCGTGAGGGACACTGGCACAGGTATAGACAAGGAGCGGCAGCAG
CTGATATTCTCCGACTTTGAACAGGCCGGCTTCCCCACGGACGGCGGCTTCGGGCTGGGGCTGGCAGTCACCTCAAGACT
GGTCTCCCTGCTCGGGGGAGACATCCGTGTGGAGAGTACGCCGGGACGTGGAAGCACTTTCGAGGTCCGGCTCCCCCTCG
GTGAGGCCGACATGCCGGATATGCGGGATGCGGCCTCCGGTGACGGCCTCCCGCTCAATATCAGGGTATTGTACATTGAT
GACGACCGGATGCAGCTGGATGCCGTCCGAAGGATGTATCTCCGTCACGGCATCGAATGTGACTGCTGCACGGACATCGA
CGGGATGGTCACGACATTGCGGAGGAACCGGCATGACCTTGTCCTGACCGACATGAGGATGTCCGATACGGACGGTTATG
GTGTGCTGGCATTGCTCCGCAACAGTAACATAGGCCAGTCCGGAACGCTCCCCGTACTGGCCGTGACCGCCCGTGTCGAC
AGCGATGCCGCCCGTTTCAGGGAGGCCGGTTTTGCCGGATGCCTGCACAAACCCTTCTCCGGGGACGAACTGATGGCGGC
CACACGGGGTGTGGAACGTCCTGACTTTACATCCGTCATGGAGGGCGAGGAACACGCGGACGAGCTGCTGGATATTTTCA
TCGAGGACACGGAGGCCGGACTTGCCGGCATACGCGATGCGGTCAGTTCGGGCGATTATAAAAAACTCGGAAATATCATA
CACAAGGCCGTCCCCGTATGGGAGACGATACGGATAGACATCCCCCTGCAGGAACTGGCATATATGGGCTCTCTGCCGCC
TGAAAAATGGGCCGGTATGTCGGACGAGCGGATCGGAAGGTTGGTCAGGGCTGTAGAGAATGCTGTAAGGAAGGCCGTAA
CATTAAAGGAGAAAATGAATGGAGACAATACTCATAGTGGAGGATGA

Upstream 100 bases:

>100_bases
TGTTGGTCGTACTTTTAGCTGTACATATATTATCTACTAATTTTCAAATATTGTGTCACGCAATTGTTATTTGTTTTAAT
TGATACTAGCCTATTCCAAG

Downstream 100 bases:

>100_bases
CCGTACATACGCACGCGCCACCGCCAACTGGCTGGCTCGAAACGGCATGGACACCCGTTACGTGCTCTCGGCGGACGCCG
CAAAGGAGTTTCTGGGCAGC

Product: two-component system histidine kinase with response regulator receiver domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MRSFLSILQLKIAGGYILLLALLCAVVFLVRLEHGKMEELDSREHSTNMRRKAVNRTFEKLLEFSFHDHFLLMQDSADIR
ECGNSCAAALDALNGLKPYYAAEQHPAIDTVSMLLLEKERLLYELTNTLSGFPRADSLLLRKAPGIVRQVRDAGQPDTPS
AKKGRGLLNVLIGGRNKKSAYANRKEKEMRNRKRQSSVNGEFIRLQKDMYSQYADYRKRLEACSDSLRCRNRELDARISG
LIHDFERAADMQYTEDMEETAALRRQSFRIILSIAVISVLLIILLYLLIHADIRKRQKYRMTLEAACSRNEELLVSRRNL
MLSVSHDLRAPLGTVCEFAELMQHEKDAGLVREFAANILHASRHVIGLANNLQHYYRLEEGKEQPENAVFHLGQTIGNAV
RVYLPSAEKKGLGLTTEIKSCDVLVRGDSGRLVRILGNLLSNAVKFTRTGYIHVGASYGNGRLLLFVRDTGTGIDKERQQ
LIFSDFEQAGFPTDGGFGLGLAVTSRLVSLLGGDIRVESTPGRGSTFEVRLPLGEADMPDMRDAASGDGLPLNIRVLYID
DDRMQLDAVRRMYLRHGIECDCCTDIDGMVTTLRRNRHDLVLTDMRMSDTDGYGVLALLRNSNIGQSGTLPVLAVTARVD
SDAARFREAGFAGCLHKPFSGDELMAATRGVERPDFTSVMEGEEHADELLDIFIEDTEAGLAGIRDAVSSGDYKKLGNII
HKAVPVWETIRIDIPLQELAYMGSLPPEKWAGMSDERIGRLVRAVENAVRKAVTLKEKMNGDNTHSGG

Sequences:

>Translated_788_residues
MRSFLSILQLKIAGGYILLLALLCAVVFLVRLEHGKMEELDSREHSTNMRRKAVNRTFEKLLEFSFHDHFLLMQDSADIR
ECGNSCAAALDALNGLKPYYAAEQHPAIDTVSMLLLEKERLLYELTNTLSGFPRADSLLLRKAPGIVRQVRDAGQPDTPS
AKKGRGLLNVLIGGRNKKSAYANRKEKEMRNRKRQSSVNGEFIRLQKDMYSQYADYRKRLEACSDSLRCRNRELDARISG
LIHDFERAADMQYTEDMEETAALRRQSFRIILSIAVISVLLIILLYLLIHADIRKRQKYRMTLEAACSRNEELLVSRRNL
MLSVSHDLRAPLGTVCEFAELMQHEKDAGLVREFAANILHASRHVIGLANNLQHYYRLEEGKEQPENAVFHLGQTIGNAV
RVYLPSAEKKGLGLTTEIKSCDVLVRGDSGRLVRILGNLLSNAVKFTRTGYIHVGASYGNGRLLLFVRDTGTGIDKERQQ
LIFSDFEQAGFPTDGGFGLGLAVTSRLVSLLGGDIRVESTPGRGSTFEVRLPLGEADMPDMRDAASGDGLPLNIRVLYID
DDRMQLDAVRRMYLRHGIECDCCTDIDGMVTTLRRNRHDLVLTDMRMSDTDGYGVLALLRNSNIGQSGTLPVLAVTARVD
SDAARFREAGFAGCLHKPFSGDELMAATRGVERPDFTSVMEGEEHADELLDIFIEDTEAGLAGIRDAVSSGDYKKLGNII
HKAVPVWETIRIDIPLQELAYMGSLPPEKWAGMSDERIGRLVRAVENAVRKAVTLKEKMNGDNTHSGG
>Mature_788_residues
MRSFLSILQLKIAGGYILLLALLCAVVFLVRLEHGKMEELDSREHSTNMRRKAVNRTFEKLLEFSFHDHFLLMQDSADIR
ECGNSCAAALDALNGLKPYYAAEQHPAIDTVSMLLLEKERLLYELTNTLSGFPRADSLLLRKAPGIVRQVRDAGQPDTPS
AKKGRGLLNVLIGGRNKKSAYANRKEKEMRNRKRQSSVNGEFIRLQKDMYSQYADYRKRLEACSDSLRCRNRELDARISG
LIHDFERAADMQYTEDMEETAALRRQSFRIILSIAVISVLLIILLYLLIHADIRKRQKYRMTLEAACSRNEELLVSRRNL
MLSVSHDLRAPLGTVCEFAELMQHEKDAGLVREFAANILHASRHVIGLANNLQHYYRLEEGKEQPENAVFHLGQTIGNAV
RVYLPSAEKKGLGLTTEIKSCDVLVRGDSGRLVRILGNLLSNAVKFTRTGYIHVGASYGNGRLLLFVRDTGTGIDKERQQ
LIFSDFEQAGFPTDGGFGLGLAVTSRLVSLLGGDIRVESTPGRGSTFEVRLPLGEADMPDMRDAASGDGLPLNIRVLYID
DDRMQLDAVRRMYLRHGIECDCCTDIDGMVTTLRRNRHDLVLTDMRMSDTDGYGVLALLRNSNIGQSGTLPVLAVTARVD
SDAARFREAGFAGCLHKPFSGDELMAATRGVERPDFTSVMEGEEHADELLDIFIEDTEAGLAGIRDAVSSGDYKKLGNII
HKAVPVWETIRIDIPLQELAYMGSLPPEKWAGMSDERIGRLVRAVENAVRKAVTLKEKMNGDNTHSGG

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=414, Percent_Identity=29.2270531400966, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1788713, Length=472, Percent_Identity=24.364406779661, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=31.1538461538462, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI1789149, Length=389, Percent_Identity=26.9922879177378, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI87081816, Length=520, Percent_Identity=24.8076923076923, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=28.4584980237154, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=256, Percent_Identity=27.34375, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=288, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=215, Percent_Identity=30.6976744186047, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=242, Percent_Identity=26.8595041322314, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786783, Length=299, Percent_Identity=24.4147157190635, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=25.9911894273128, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87958; Mature: 87958

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFLSILQLKIAGGYILLLALLCAVVFLVRLEHGKMEELDSREHSTNMRRKAVNRTFEK
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHH
LLEFSFHDHFLLMQDSADIRECGNSCAAALDALNGLKPYYAAEQHPAIDTVSMLLLEKER
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LLYELTNTLSGFPRADSLLLRKAPGIVRQVRDAGQPDTPSAKKGRGLLNVLIGGRNKKSA
HHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHH
YANRKEKEMRNRKRQSSVNGEFIRLQKDMYSQYADYRKRLEACSDSLRCRNRELDARISG
HHCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LIHDFERAADMQYTEDMEETAALRRQSFRIILSIAVISVLLIILLYLLIHADIRKRQKYR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTLEAACSRNEELLVSRRNLMLSVSHDLRAPLGTVCEFAELMQHEKDAGLVREFAANILH
HHHHHHHCCCHHHHHHHCCEEEEECHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASRHVIGLANNLQHYYRLEEGKEQPENAVFHLGQTIGNAVRVYLPSAEKKGLGLTTEIKS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEECCC
CDVLVRGDSGRLVRILGNLLSNAVKFTRTGYIHVGASYGNGRLLLFVRDTGTGIDKERQQ
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHH
LIFSDFEQAGFPTDGGFGLGLAVTSRLVSLLGGDIRVESTPGRGSTFEVRLPLGEADMPD
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCC
MRDAASGDGLPLNIRVLYIDDDRMQLDAVRRMYLRHGIECDCCTDIDGMVTTLRRNRHDL
CHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCE
VLTDMRMSDTDGYGVLALLRNSNIGQSGTLPVLAVTARVDSDAARFREAGFAGCLHKPFS
EEEECEECCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHCCHHHHCCCCC
GDELMAATRGVERPDFTSVMEGEEHADELLDIFIEDTEAGLAGIRDAVSSGDYKKLGNII
CCHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
HKAVPVWETIRIDIPLQELAYMGSLPPEKWAGMSDERIGRLVRAVENAVRKAVTLKEKMN
HHHCCCCEEEEECCCHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GDNTHSGG
CCCCCCCC
>Mature Secondary Structure
MRSFLSILQLKIAGGYILLLALLCAVVFLVRLEHGKMEELDSREHSTNMRRKAVNRTFEK
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHH
LLEFSFHDHFLLMQDSADIRECGNSCAAALDALNGLKPYYAAEQHPAIDTVSMLLLEKER
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LLYELTNTLSGFPRADSLLLRKAPGIVRQVRDAGQPDTPSAKKGRGLLNVLIGGRNKKSA
HHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHH
YANRKEKEMRNRKRQSSVNGEFIRLQKDMYSQYADYRKRLEACSDSLRCRNRELDARISG
HHCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LIHDFERAADMQYTEDMEETAALRRQSFRIILSIAVISVLLIILLYLLIHADIRKRQKYR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTLEAACSRNEELLVSRRNLMLSVSHDLRAPLGTVCEFAELMQHEKDAGLVREFAANILH
HHHHHHHCCCHHHHHHHCCEEEEECHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASRHVIGLANNLQHYYRLEEGKEQPENAVFHLGQTIGNAVRVYLPSAEKKGLGLTTEIKS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEECCC
CDVLVRGDSGRLVRILGNLLSNAVKFTRTGYIHVGASYGNGRLLLFVRDTGTGIDKERQQ
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHH
LIFSDFEQAGFPTDGGFGLGLAVTSRLVSLLGGDIRVESTPGRGSTFEVRLPLGEADMPD
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCC
MRDAASGDGLPLNIRVLYIDDDRMQLDAVRRMYLRHGIECDCCTDIDGMVTTLRRNRHDL
CHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCE
VLTDMRMSDTDGYGVLALLRNSNIGQSGTLPVLAVTARVDSDAARFREAGFAGCLHKPFS
EEEECEECCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHCCHHHHCCCCC
GDELMAATRGVERPDFTSVMEGEEHADELLDIFIEDTEAGLAGIRDAVSSGDYKKLGNII
CCHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
HKAVPVWETIRIDIPLQELAYMGSLPPEKWAGMSDERIGRLVRAVENAVRKAVTLKEKMN
HHHCCCCEEEEECCCHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GDNTHSGG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]