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The map label for this gene is yfbL [C]

Identifier: 150004418

GI number: 150004418

Start: 2435223

End: 2436242

Strand: Reverse

Name: yfbL [C]

Synonym: BVU_1865

Alternate gene names: 150004418

Gene position: 2436242-2435223 (Counterclockwise)

Preceding gene: 150004419

Following gene: 150004417

Centisome position: 47.18

GC content: 45.49

Gene sequence:

>1020_bases
ATGAAAAAACACCTCTTAGCTATTGCACTGTTTGCATTATGCACCACCGGGCTGAATGCCGCTTCTCCTAAAAAAGTAGC
TCCTGAAAAAAAAGGAGTAGAAACCATTAACCGTGCCACAGCCGAAGCACATATCGGCTTTTTGGCCTGTGACGAACTGG
AAGGACGCGAAGCCGGATGGAAAGGTGGACGCATTGCAGGCAATTATATCATTTCCTGCCTGAAACAGATGGGAATAAAG
CCACTGGACGGAGACTATATACAGCCCTTTGACGTGTATCATGCTGAACGGCAAGTGAAAGGGAAACGCTGGCAAGTACA
TCCCGATTCTATTGCGGAACTGAAAAAAGTGGTATATCAAAAATTGGCATTACGTAATATCTTAGGTAAAATAGAAGGAA
AGAATCCAAATGAAATTGTCATTATCGGTGCACATTACGACCACATAGGCTACGATCCGATGCTGGAAGGAGATCAGATT
TATAACGGTGCAGATGATAATGCATCAGGCGTTCAAGCCGTATTACAGGTAGCCCGTGCTTTTCTTGCTACCGGCGAGCA
GCCGGAACGTACCGTTATCTTCGCTTTTTGGGATGGTGAGGAAAAGGGATTGCTGGGCTCCCGTTATTTCGCCATGAACT
ATCCGGATATTAAAAAGGTAAAAGGCTATTTGAACTATGACATGATAGGACGTAACAACCGGGAGGACCAGCCCGATTAT
TTCGTTTACTTCTATACCGCAGCCCATCAGGCCTTCGGTGACTGGCTGAAAAAAGATATTGAGGATTACCGCTTGCAGTT
ATCCCCTGACTACCGGGCTTGGGACAATCCGGTGGGAGGCAGCGACAACGGCACGTTCGCCAAACTGGGAATACCTATTA
TATGGTATCACACTGATGCCCATCCCGATTATCACCTTCCGGGAGATGAAACACAGAAAATCAATTGGCTGAAGATAGTC
GATATAACCAAAGCCTCTTTCCTTGCGATGTGGAAACTGGCAAACGAAAAAAAATATTAA

Upstream 100 bases:

>100_bases
AAACATCTAATCAGCGAGTCACGCTATACTTCTTACCTGAATATGTTGGAAGACAAGGAAGAAGGCAAGTATCGCGCCGC
TTACTAAAAACCACAACTTT

Downstream 100 bases:

>100_bases
AAAAGAACGTGGCGTTTAAACTGAACGCCACGTTTTTTTATCTAATCTTACATTAACGTATTTATTAAACCCATATAGAA
AGGCACATGAACAAACGAAT

Product: aminopeptidase

Products: NA

Alternate protein names: SGAP [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKKHLLAIALFALCTTGLNAASPKKVAPEKKGVETINRATAEAHIGFLACDELEGREAGWKGGRIAGNYIISCLKQMGIK
PLDGDYIQPFDVYHAERQVKGKRWQVHPDSIAELKKVVYQKLALRNILGKIEGKNPNEIVIIGAHYDHIGYDPMLEGDQI
YNGADDNASGVQAVLQVARAFLATGEQPERTVIFAFWDGEEKGLLGSRYFAMNYPDIKKVKGYLNYDMIGRNNREDQPDY
FVYFYTAAHQAFGDWLKKDIEDYRLQLSPDYRAWDNPVGGSDNGTFAKLGIPIIWYHTDAHPDYHLPGDETQKINWLKIV
DITKASFLAMWKLANEKKY

Sequences:

>Translated_339_residues
MKKHLLAIALFALCTTGLNAASPKKVAPEKKGVETINRATAEAHIGFLACDELEGREAGWKGGRIAGNYIISCLKQMGIK
PLDGDYIQPFDVYHAERQVKGKRWQVHPDSIAELKKVVYQKLALRNILGKIEGKNPNEIVIIGAHYDHIGYDPMLEGDQI
YNGADDNASGVQAVLQVARAFLATGEQPERTVIFAFWDGEEKGLLGSRYFAMNYPDIKKVKGYLNYDMIGRNNREDQPDY
FVYFYTAAHQAFGDWLKKDIEDYRLQLSPDYRAWDNPVGGSDNGTFAKLGIPIIWYHTDAHPDYHLPGDETQKINWLKIV
DITKASFLAMWKLANEKKY
>Mature_339_residues
MKKHLLAIALFALCTTGLNAASPKKVAPEKKGVETINRATAEAHIGFLACDELEGREAGWKGGRIAGNYIISCLKQMGIK
PLDGDYIQPFDVYHAERQVKGKRWQVHPDSIAELKKVVYQKLALRNILGKIEGKNPNEIVIIGAHYDHIGYDPMLEGDQI
YNGADDNASGVQAVLQVARAFLATGEQPERTVIFAFWDGEEKGLLGSRYFAMNYPDIKKVKGYLNYDMIGRNNREDQPDY
FVYFYTAAHQAFGDWLKKDIEDYRLQLSPDYRAWDNPVGGSDNGTFAKLGIPIIWYHTDAHPDYHLPGDETQKINWLKIV
DITKASFLAMWKLANEKKY

Specific function: Specific for larger hydrophobic acids, especially leucine. No cleavage occurs if the next residue is proline [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28A subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI71984813, Length=213, Percent_Identity=31.924882629108, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25147314, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71995331, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71995324, Length=209, Percent_Identity=28.7081339712919, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6320623, Length=174, Percent_Identity=35.0574712643678, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484 [H]

Pfam domain/function: PF04389 Peptidase_M28 [H]

EC number: =3.4.11.24 [H]

Molecular weight: Translated: 38318; Mature: 38318

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHLLAIALFALCTTGLNAASPKKVAPEKKGVETINRATAEAHIGFLACDELEGREAGW
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCC
KGGRIAGNYIISCLKQMGIKPLDGDYIQPFDVYHAERQVKGKRWQVHPDSIAELKKVVYQ
CCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
KLALRNILGKIEGKNPNEIVIIGAHYDHIGYDPMLEGDQIYNGADDNASGVQAVLQVARA
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHH
FLATGEQPERTVIFAFWDGEEKGLLGSRYFAMNYPDIKKVKGYLNYDMIGRNNREDQPDY
HHHCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHCCEEECCCCCCCCCCCE
FVYFYTAAHQAFGDWLKKDIEDYRLQLSPDYRAWDNPVGGSDNGTFAKLGIPIIWYHTDA
EEEEEHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEECCEEEEEECCC
HPDYHLPGDETQKINWLKIVDITKASFLAMWKLANEKKY
CCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKHLLAIALFALCTTGLNAASPKKVAPEKKGVETINRATAEAHIGFLACDELEGREAGW
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCC
KGGRIAGNYIISCLKQMGIKPLDGDYIQPFDVYHAERQVKGKRWQVHPDSIAELKKVVYQ
CCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
KLALRNILGKIEGKNPNEIVIIGAHYDHIGYDPMLEGDQIYNGADDNASGVQAVLQVARA
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHH
FLATGEQPERTVIFAFWDGEEKGLLGSRYFAMNYPDIKKVKGYLNYDMIGRNNREDQPDY
HHHCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHCCEEECCCCCCCCCCCE
FVYFYTAAHQAFGDWLKKDIEDYRLQLSPDYRAWDNPVGGSDNGTFAKLGIPIIWYHTDA
EEEEEHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEECCEEEEEECCC
HPDYHLPGDETQKINWLKIVDITKASFLAMWKLANEKKY
CCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8665903; 2503378; 8444149; 9048953 [H]