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The map label for this gene is tdk

Identifier: 150004389

GI number: 150004389

Start: 2381409

End: 2382008

Strand: Reverse

Name: tdk

Synonym: BVU_1836

Alternate gene names: 150004389

Gene position: 2382008-2381409 (Counterclockwise)

Preceding gene: 150004393

Following gene: 150004388

Centisome position: 46.13

GC content: 45.0

Gene sequence:

>600_bases
ATGGTAGTTTTTTCAGAAGACCACATCCAGGAAACACGTAGAAGAGGAAGAATAGAAGTAATATGCGGCTCAATGTTCTC
AGGTAAAACCGAGGAACTAATCCGCCGTTTGAAAAGAGCGAAGTTTGCCCGTCAACGGGTTGAAATATTCAAACCGGCCA
TAGATACACGCTATTCGGAAGAAGAAGTTGTATCACATGACAGCAACTCTATTGCCTCCACCCCTATTGATTCTTCTGCC
AGCATCTTGCTTTTCTCCTCAGACAAGGATGTAGTGGGTATAGACGAAGCGCAATTTTTTGACGAAGGTTTGGTTGATGT
CTGCAACAAGCTGGCTGACAACGGGATAAGAGTCATTGTCGCCGGATTGGACATGGATTTCAGGAGAGTTCCTTTCGGAC
CTATACCTGCCTTGCTGGCTATTGCAGACGAAGTAACCAAAGTTCATGCCATTTGTGTGAAATGTGGGAACTTGGCCTAT
GCCACCCACCGAATCACCAAAAGCGAAAAACGGGTCCTATTAGGGGAAAAGGCAGACTATGAGCCTCTTTGCCGGACCTG
CTATATGGAAGCTTTGAAAGAGGAAACTGAAAATAAATAA

Upstream 100 bases:

>100_bases
TATATCTTTTATTAATAAATTTCCAAGTGAAAATAATCCTTTTTCGGGGTACAAGTCGTACATTTGCACTCAGAATTAAT
CTAATTGTTATAACTAAATT

Downstream 100 bases:

>100_bases
CACACACTTTATGATACAGAAAAAAATAACATTCGATAGTTTTATCCGCGGAATATTGACAGCGATGGTCATTATCGGCA
TTCTATATCTGGTCAACCGA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MVVFSEDHIQETRRRGRIEVICGSMFSGKTEELIRRLKRAKFARQRVEIFKPAIDTRYSEEEVVSHDSNSIASTPIDSSA
SILLFSSDKDVVGIDEAQFFDEGLVDVCNKLADNGIRVIVAGLDMDFRRVPFGPIPALLAIADEVTKVHAICVKCGNLAY
ATHRITKSEKRVLLGEKADYEPLCRTCYMEALKEETENK

Sequences:

>Translated_199_residues
MVVFSEDHIQETRRRGRIEVICGSMFSGKTEELIRRLKRAKFARQRVEIFKPAIDTRYSEEEVVSHDSNSIASTPIDSSA
SILLFSSDKDVVGIDEAQFFDEGLVDVCNKLADNGIRVIVAGLDMDFRRVPFGPIPALLAIADEVTKVHAICVKCGNLAY
ATHRITKSEKRVLLGEKADYEPLCRTCYMEALKEETENK
>Mature_199_residues
MVVFSEDHIQETRRRGRIEVICGSMFSGKTEELIRRLKRAKFARQRVEIFKPAIDTRYSEEEVVSHDSNSIASTPIDSSA
SILLFSSDKDVVGIDEAQFFDEGLVDVCNKLADNGIRVIVAGLDMDFRRVPFGPIPALLAIADEVTKVHAICVKCGNLAY
ATHRITKSEKRVLLGEKADYEPLCRTCYMEALKEETENK

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Homo sapiens, GI164698438, Length=179, Percent_Identity=37.9888268156425, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17543396, Length=186, Percent_Identity=38.7096774193548, Blast_Score=117, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_BACV8 (A6L1E7)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299133.1
- ProteinModelPortal:   A6L1E7
- SMR:   A6L1E7
- STRING:   A6L1E7
- GeneID:   5302802
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1836
- NMPDR:   fig|435590.6.peg.1727
- eggNOG:   COG1435
- HOGENOM:   HBG522108
- OMA:   VITGPMY
- ProtClustDB:   PRK04296
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 22372; Mature: 22372

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 96-96

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVFSEDHIQETRRRGRIEVICGSMFSGKTEELIRRLKRAKFARQRVEIFKPAIDTRYSE
CEEECHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EEVVSHDSNSIASTPIDSSASILLFSSDKDVVGIDEAQFFDEGLVDVCNKLADNGIRVIV
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHCCCEEEEE
AGLDMDFRRVPFGPIPALLAIADEVTKVHAICVKCGNLAYATHRITKSEKRVLLGEKADY
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCH
EPLCRTCYMEALKEETENK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVFSEDHIQETRRRGRIEVICGSMFSGKTEELIRRLKRAKFARQRVEIFKPAIDTRYSE
CEEECHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EEVVSHDSNSIASTPIDSSASILLFSSDKDVVGIDEAQFFDEGLVDVCNKLADNGIRVIV
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHCCCEEEEE
AGLDMDFRRVPFGPIPALLAIADEVTKVHAICVKCGNLAYATHRITKSEKRVLLGEKADY
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCH
EPLCRTCYMEALKEETENK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA