Click here to switch to the map view.

The map label for this gene is obgE

Identifier: 150004242

GI number: 150004242

Start: 2173875

End: 2175059

Strand: Direct

Name: obgE

Synonym: BVU_1683

Alternate gene names: 150004242

Gene position: 2173875-2175059 (Clockwise)

Preceding gene: 150004241

Following gene: 150004243

Centisome position: 42.1

GC content: 45.23

Gene sequence:

>1185_bases
ATGGCTGAATCGAATTTTGTTGATTATGTGAAGATATATTGCCGCTCGGGTAAGGGCGGGCGAGGCTCTGCGCATATGCG
TCGTGAGAAGTATGTACCCAATGGTGGCCCTGACGGTGGTGATGGCGGTAGAGGAGGTCATGTTATTTTGCGGGGAAACC
GTAATTATTGGACATTGCTTCACCTGAAGTATGACCGCCACGTGTTTGCCACACACGGCGGCAATGGATCGAAGAACAAA
AGCTTTGGTAAAGATGGTGAAGACAAAGTTATTGAAGTACCTTGTGGTACAGTGGTTTATAATGCTGAAACAGGTGAATA
TATCTGTGATATCACCGAACACGGACAAGAAATAATTCTGTTGAAAGGAGGACGTGGGGGATTGGGAAACTGGCACTTCC
GTACAGCAACCCGTCAGGCGCCACGTTTTGCACAACCGGGAGAACCCATGCAGGAGCTGATGGTTATTTTGGAATTAAAA
CTGTTGGCTGATGTAGGTTTGGTAGGTTTTCCAAATGCAGGGAAATCCACTTTATTGTCTACCGTATCGGCGGCACGTCC
TAAAATAGCCAATTATCCGTTTACTACGCTGGAGCCGAATTTGGGTATCGTGTCCTATCGCGAAGGAAAATCTTTTGTCA
TGGCGGATATTCCCGGAATTATTGAAGGGGCCAGTGAGGGAAAAGGACTGGGACTTCGTTTCCTGCGCCATATAGAACGC
AACTCTTTGTTGCTCTTTATGGTACCGGGTGATACAGATGATATCCGTAAGGAATATGAAATCCTGCTGAATGAGTTGGC
TACCTTCAACCCGGAAATGTTGGATAAACAACGTGTGCTTGCCATTACCAAAAGTGACATGTTGGATGAAGAACTGATTG
CCATGTTGGAGCCGACATTGCCGGATAATGTTCCGCATATCTTTATCTCGTCGGTAACTGGCTTGGGGATACAGCAGCTG
AAGGATATTTTATGGACAGAATTGAATAAGGACAGCAATAAGTTGGAAGGTGTCCGTACGGAAACAATTGTTCATCGCGC
CAAAGATGTTGCCAAACTGCAGGAAGAGTTGAAAGACATGGGTGAGGATGAGGACTTTGAATATGAATATGAAGAAGATG
CCGATGATGACTTCGATTATGAATATGAAGATGAGAATTGGGACGAAGAAGAGGAAAAGAAATGA

Upstream 100 bases:

>100_bases
CTGATGCAGCAGTCCGCCAATGTGTCAGTCTGCATAATGATACATGGAGTACAGTTTCGTTGGCACATTAGTAAATTGAT
AAATTAGTAAATTATTAATT

Downstream 100 bases:

>100_bases
AACGGCTGACATCAGATAATAAAATGTTGGGATATGAGCTGATGAAGGCATATCCCAACATTTCTTGTTTTTCTACCACC
CGTCACGGAGGTTGTAGTAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MAESNFVDYVKIYCRSGKGGRGSAHMRREKYVPNGGPDGGDGGRGGHVILRGNRNYWTLLHLKYDRHVFATHGGNGSKNK
SFGKDGEDKVIEVPCGTVVYNAETGEYICDITEHGQEIILLKGGRGGLGNWHFRTATRQAPRFAQPGEPMQELMVILELK
LLADVGLVGFPNAGKSTLLSTVSAARPKIANYPFTTLEPNLGIVSYREGKSFVMADIPGIIEGASEGKGLGLRFLRHIER
NSLLLFMVPGDTDDIRKEYEILLNELATFNPEMLDKQRVLAITKSDMLDEELIAMLEPTLPDNVPHIFISSVTGLGIQQL
KDILWTELNKDSNKLEGVRTETIVHRAKDVAKLQEELKDMGEDEDFEYEYEEDADDDFDYEYEDENWDEEEEKK

Sequences:

>Translated_394_residues
MAESNFVDYVKIYCRSGKGGRGSAHMRREKYVPNGGPDGGDGGRGGHVILRGNRNYWTLLHLKYDRHVFATHGGNGSKNK
SFGKDGEDKVIEVPCGTVVYNAETGEYICDITEHGQEIILLKGGRGGLGNWHFRTATRQAPRFAQPGEPMQELMVILELK
LLADVGLVGFPNAGKSTLLSTVSAARPKIANYPFTTLEPNLGIVSYREGKSFVMADIPGIIEGASEGKGLGLRFLRHIER
NSLLLFMVPGDTDDIRKEYEILLNELATFNPEMLDKQRVLAITKSDMLDEELIAMLEPTLPDNVPHIFISSVTGLGIQQL
KDILWTELNKDSNKLEGVRTETIVHRAKDVAKLQEELKDMGEDEDFEYEYEEDADDDFDYEYEDENWDEEEEKK
>Mature_393_residues
AESNFVDYVKIYCRSGKGGRGSAHMRREKYVPNGGPDGGDGGRGGHVILRGNRNYWTLLHLKYDRHVFATHGGNGSKNKS
FGKDGEDKVIEVPCGTVVYNAETGEYICDITEHGQEIILLKGGRGGLGNWHFRTATRQAPRFAQPGEPMQELMVILELKL
LADVGLVGFPNAGKSTLLSTVSAARPKIANYPFTTLEPNLGIVSYREGKSFVMADIPGIIEGASEGKGLGLRFLRHIERN
SLLLFMVPGDTDDIRKEYEILLNELATFNPEMLDKQRVLAITKSDMLDEELIAMLEPTLPDNVPHIFISSVTGLGIQQLK
DILWTELNKDSNKLEGVRTETIVHRAKDVAKLQEELKDMGEDEDFEYEYEEDADDDFDYEYEDENWDEEEEKK

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=316, Percent_Identity=41.1392405063291, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI111955139, Length=362, Percent_Identity=34.2541436464088, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI111955063, Length=288, Percent_Identity=33.6805555555556, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=36.2204724409449, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4557537, Length=95, Percent_Identity=35.7894736842105, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=44.8170731707317, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787454, Length=90, Percent_Identity=37.7777777777778, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=330, Percent_Identity=36.969696969697, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=306, Percent_Identity=27.7777777777778, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71981008, Length=95, Percent_Identity=43.1578947368421, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17555344, Length=86, Percent_Identity=43.0232558139535, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=138, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=163, Percent_Identity=42.9447852760736, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319281, Length=87, Percent_Identity=43.6781609195402, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=86, Percent_Identity=43.0232558139535, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24585318, Length=231, Percent_Identity=43.7229437229437, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI20129375, Length=218, Percent_Identity=39.4495412844037, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21356473, Length=96, Percent_Identity=40.625, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17981711, Length=86, Percent_Identity=47.6744186046512, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24640873, Length=165, Percent_Identity=30.9090909090909, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640877, Length=165, Percent_Identity=30.9090909090909, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640875, Length=165, Percent_Identity=30.9090909090909, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BACV8 (A6L100)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298986.1
- ProteinModelPortal:   A6L100
- SMR:   A6L100
- STRING:   A6L100
- GeneID:   5302649
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1683
- NMPDR:   fig|435590.6.peg.1589
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12298
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 44178; Mature: 44047

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESNFVDYVKIYCRSGKGGRGSAHMRREKYVPNGGPDGGDGGRGGHVILRGNRNYWTLL
CCCCHHHHEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEE
HLKYDRHVFATHGGNGSKNKSFGKDGEDKVIEVPCGTVVYNAETGEYICDITEHGQEIIL
EEEECCEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCEEEEECCCCCEEEE
LKGGRGGLGNWHFRTATRQAPRFAQPGEPMQELMVILELKLLADVGLVGFPNAGKSTLLS
EECCCCCCCCCEEECHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHH
TVSAARPKIANYPFTTLEPNLGIVSYREGKSFVMADIPGIIEGASEGKGLGLRFLRHIER
HHHHCCCCCCCCCCCEECCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHCC
NSLLLFMVPGDTDDIRKEYEILLNELATFNPEMLDKQRVLAITKSDMLDEELIAMLEPTL
CCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHCCCC
PDNVPHIFISSVTGLGIQQLKDILWTELNKDSNKLEGVRTETIVHRAKDVAKLQEELKDM
CCCCCEEEEHHHCCCCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GEDEDFEYEYEEDADDDFDYEYEDENWDEEEEKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
AESNFVDYVKIYCRSGKGGRGSAHMRREKYVPNGGPDGGDGGRGGHVILRGNRNYWTLL
CCCHHHHEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEE
HLKYDRHVFATHGGNGSKNKSFGKDGEDKVIEVPCGTVVYNAETGEYICDITEHGQEIIL
EEEECCEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCEEEEECCCCCEEEE
LKGGRGGLGNWHFRTATRQAPRFAQPGEPMQELMVILELKLLADVGLVGFPNAGKSTLLS
EECCCCCCCCCEEECHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHH
TVSAARPKIANYPFTTLEPNLGIVSYREGKSFVMADIPGIIEGASEGKGLGLRFLRHIER
HHHHCCCCCCCCCCCEECCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHCC
NSLLLFMVPGDTDDIRKEYEILLNELATFNPEMLDKQRVLAITKSDMLDEELIAMLEPTL
CCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHCCCC
PDNVPHIFISSVTGLGIQQLKDILWTELNKDSNKLEGVRTETIVHRAKDVAKLQEELKDM
CCCCCEEEEHHHCCCCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GEDEDFEYEYEEDADDDFDYEYEDENWDEEEEKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA