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The map label for this gene is zraR [H]

Identifier: 150004118

GI number: 150004118

Start: 2043472

End: 2044785

Strand: Direct

Name: zraR [H]

Synonym: BVU_1553

Alternate gene names: 150004118

Gene position: 2043472-2044785 (Clockwise)

Preceding gene: 150004117

Following gene: 150004123

Centisome position: 39.58

GC content: 51.14

Gene sequence:

>1314_bases
ATGACGGGGATGAAAAAGACTTTATTGATCGTGGAGGACAACCTGATTCTTTGCGATATTCTTGAGAGATGGCTACAGAA
AGCCGGTTACAGGGTATTGACGGCCATAGATGAGCCTTCGGCACGCCGGAAAATCAAGGGGAATAACGTGGCGCTGGTAC
TGACGGATGTCCGCCTTCCCGAAGGGGATGGCATCAGTTTACTGGAATGGAGCATCTCCCAAGGGTTACATATCCCTTTT
GTGGTGATGACCGAACATGCCTCCATTGCAGATGCGGTGCGTGCCGTCAAATTGGGCGCAAAGGACTACTTGCCCAAGCC
TGTCCACGAGGAGTTACTGATGGAACTGTTACGGGGATTGATCGGTCTGCCAGTTTCCGTTCCCCCGAAGAAATCATTAA
TGAAAAGGCTTAGCGGGGCGGTCCGGGAGACCGAGCGGATAGCTTGTCGTGTGGCTCCTTTGAATTGTTCCGTCATGATC
CTTGGACCGAACGGTAGCGGAAAAGAATCTGTCGCACAGCTGATCCAACAGCATAGCGGGCGTAAGGACAAGCCTTTTGT
GGCGGTGAACTGTGGTTGTATCCGGGGGGAACTTGCCGCATCTGAGTTCTTCGGTCACGTGCAGGGGGCATTTACCGATG
CGAAAAAGGATACTGCCGGCTATTTTGAGACGGCCAAGGGCGGTACGCTCTTCCTTGACGAGATCGGAAACATGCCTCCC
GAAATGCAGACACTGCTGCTCAGGGTATTACAGGAAAGAGTGTATTGTCCAGTGGGCAGCCGCAAAGAACTTGAAGCCGA
TGTACGGATATTGTCGGCCACCAACGAGGATATGGAGCGTGCCATACGGGAGGGACGTTTCCGGGAGGATCTGTACTACC
GTCTCGCCGAGTTTGAGATACGCCAGCCCTCTCTCTCCGAATGCCCGGAAGATATATTGCCACTGGCTGACTTCTTTCGT
GAGCAACATTCAGAAGAGATACGTGTGGAGACCTCCGGTTTTACCGAACAAGCCAAAATCTCCATGCTTTCCCACTCATG
GCCGGGCAATGTGCGTGAACTTGACAACCGGATAAGACGTGCTGTCCTGTTGGCGGTATCTCCATTGTTAACCCATAAAG
ATCTGAATCTTAATGCGACCATCTGTAGGACAGGCGAAAAATGTAAAAAAGGCTTGATGGAAGAAGCAGAAGAGAAAGAA
CTAATAAGGAAGATTCTGGAAGAATGTGGAGGTAAGATCAGTCGTGTGGCGAGAATGTTGGGGATGAGCCGTCCGACGCT
ATACAAGAAAATGGAAAGGTATGGGTTGAGATAG

Upstream 100 bases:

>100_bases
AAGACCTCGAGCGACGAGACGGTCAGAGAGTACACGATGAGAATTATGAAACAGATACGGTTACTGATAGACGAAGTAAA
TAATGAATTAAGAAAGAAAA

Downstream 100 bases:

>100_bases
CATCTTCATCCGTTTCGTTTATACATAAGCCGGCAGATTCCGTTGGAGAAAGTTTTGCAGCCAAGAAGTTTCCAGCGGGC
AGACCGGAATTCTCCCGTCA

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTGMKKTLLIVEDNLILCDILERWLQKAGYRVLTAIDEPSARRKIKGNNVALVLTDVRLPEGDGISLLEWSISQGLHIPF
VVMTEHASIADAVRAVKLGAKDYLPKPVHEELLMELLRGLIGLPVSVPPKKSLMKRLSGAVRETERIACRVAPLNCSVMI
LGPNGSGKESVAQLIQQHSGRKDKPFVAVNCGCIRGELAASEFFGHVQGAFTDAKKDTAGYFETAKGGTLFLDEIGNMPP
EMQTLLLRVLQERVYCPVGSRKELEADVRILSATNEDMERAIREGRFREDLYYRLAEFEIRQPSLSECPEDILPLADFFR
EQHSEEIRVETSGFTEQAKISMLSHSWPGNVRELDNRIRRAVLLAVSPLLTHKDLNLNATICRTGEKCKKGLMEEAEEKE
LIRKILEECGGKISRVARMLGMSRPTLYKKMERYGLR

Sequences:

>Translated_437_residues
MTGMKKTLLIVEDNLILCDILERWLQKAGYRVLTAIDEPSARRKIKGNNVALVLTDVRLPEGDGISLLEWSISQGLHIPF
VVMTEHASIADAVRAVKLGAKDYLPKPVHEELLMELLRGLIGLPVSVPPKKSLMKRLSGAVRETERIACRVAPLNCSVMI
LGPNGSGKESVAQLIQQHSGRKDKPFVAVNCGCIRGELAASEFFGHVQGAFTDAKKDTAGYFETAKGGTLFLDEIGNMPP
EMQTLLLRVLQERVYCPVGSRKELEADVRILSATNEDMERAIREGRFREDLYYRLAEFEIRQPSLSECPEDILPLADFFR
EQHSEEIRVETSGFTEQAKISMLSHSWPGNVRELDNRIRRAVLLAVSPLLTHKDLNLNATICRTGEKCKKGLMEEAEEKE
LIRKILEECGGKISRVARMLGMSRPTLYKKMERYGLR
>Mature_436_residues
TGMKKTLLIVEDNLILCDILERWLQKAGYRVLTAIDEPSARRKIKGNNVALVLTDVRLPEGDGISLLEWSISQGLHIPFV
VMTEHASIADAVRAVKLGAKDYLPKPVHEELLMELLRGLIGLPVSVPPKKSLMKRLSGAVRETERIACRVAPLNCSVMIL
GPNGSGKESVAQLIQQHSGRKDKPFVAVNCGCIRGELAASEFFGHVQGAFTDAKKDTAGYFETAKGGTLFLDEIGNMPPE
MQTLLLRVLQERVYCPVGSRKELEADVRILSATNEDMERAIREGRFREDLYYRLAEFEIRQPSLSECPEDILPLADFFRE
QHSEEIRVETSGFTEQAKISMLSHSWPGNVRELDNRIRRAVLLAVSPLLTHKDLNLNATICRTGEKCKKGLMEEAEEKEL
IRKILEECGGKISRVARMLGMSRPTLYKKMERYGLR

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=442, Percent_Identity=38.6877828054299, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788905, Length=446, Percent_Identity=37.6681614349776, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1788550, Length=457, Percent_Identity=34.7921225382932, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1790299, Length=464, Percent_Identity=32.7586206896552, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1789233, Length=345, Percent_Identity=35.9420289855072, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87082117, Length=304, Percent_Identity=39.4736842105263, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1789087, Length=289, Percent_Identity=38.7543252595156, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1786524, Length=306, Percent_Identity=37.5816993464052, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=33.9622641509434, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=36.7601246105919, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=40.1709401709402, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789828, Length=241, Percent_Identity=34.0248962655602, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081858, Length=286, Percent_Identity=31.4685314685315, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=136, Percent_Identity=33.0882352941176, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789809, Length=114, Percent_Identity=28.0701754385965, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49025; Mature: 48894

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMKKTLLIVEDNLILCDILERWLQKAGYRVLTAIDEPSARRKIKGNNVALVLTDVRLP
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHCEECCCCEEEEEEEEECC
EGDGISLLEWSISQGLHIPFVVMTEHASIADAVRAVKLGAKDYLPKPVHEELLMELLRGL
CCCCCEEEEEHHHCCCCCCEEEEECCHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
IGLPVSVPPKKSLMKRLSGAVRETERIACRVAPLNCSVMILGPNGSGKESVAQLIQQHSG
HCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCC
RKDKPFVAVNCGCIRGELAASEFFGHVQGAFTDAKKDTAGYFETAKGGTLFLDEIGNMPP
CCCCCEEEEECCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHCCCCH
EMQTLLLRVLQERVYCPVGSRKELEADVRILSATNEDMERAIREGRFREDLYYRLAEFEI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHEEECCCHHHHHHHHCCCHHHHHHHHHHHHHC
RQPSLSECPEDILPLADFFREQHSEEIRVETSGFTEQAKISMLSHSWPGNVRELDNRIRR
CCCCHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHH
AVLLAVSPLLTHKDLNLNATICRTGEKCKKGLMEEAEEKELIRKILEECGGKISRVARML
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GMSRPTLYKKMERYGLR
CCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TGMKKTLLIVEDNLILCDILERWLQKAGYRVLTAIDEPSARRKIKGNNVALVLTDVRLP
CCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHCEECCCCEEEEEEEEECC
EGDGISLLEWSISQGLHIPFVVMTEHASIADAVRAVKLGAKDYLPKPVHEELLMELLRGL
CCCCCEEEEEHHHCCCCCCEEEEECCHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
IGLPVSVPPKKSLMKRLSGAVRETERIACRVAPLNCSVMILGPNGSGKESVAQLIQQHSG
HCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCC
RKDKPFVAVNCGCIRGELAASEFFGHVQGAFTDAKKDTAGYFETAKGGTLFLDEIGNMPP
CCCCCEEEEECCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHCCCCH
EMQTLLLRVLQERVYCPVGSRKELEADVRILSATNEDMERAIREGRFREDLYYRLAEFEI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHEEECCCHHHHHHHHCCCHHHHHHHHHHHHHC
RQPSLSECPEDILPLADFFREQHSEEIRVETSGFTEQAKISMLSHSWPGNVRELDNRIRR
CCCCHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHH
AVLLAVSPLLTHKDLNLNATICRTGEKCKKGLMEEAEEKELIRKILEECGGKISRVARML
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GMSRPTLYKKMERYGLR
CCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]