Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 150004117

GI number: 150004117

Start: 2041149

End: 2043536

Strand: Direct

Name: luxQ [H]

Synonym: BVU_1552

Alternate gene names: 150004117

Gene position: 2041149-2043536 (Clockwise)

Preceding gene: 150004116

Following gene: 150004118

Centisome position: 39.53

GC content: 48.58

Gene sequence:

>2388_bases
ATGAAAATATTTATGGTAGCAAGGAAAGTTTCATTACAGCATAAGGTTCTTTTAGGGTATATGATATTGATCATGGCTGT
TTGCGGCATGGTTTCCATCTTGTTATACGAACGGAGCCGCATGCGTGAGATAAAAACGGAAACATCGGAGATACGCAGGA
TACGCCATGACATCAGTACGGCGCATCGCTATATCACGGAGCTTGCCACCTATGGAGAGTCCGTCATTGTCTGGGAGGAT
ACCGATTTTCGTGAGTATCGCAGAAAACGCTTGCAAACGGACAGCTTGTTACAAATATTGAAAGTGAGTTGTGGCACGTT
CGTCCTGCCAAAGCAGATAGACTCCCTATGTCATTTATTGGAAGCTAAGGAGATACATCTGCTCCGCATTATGGAGACCA
TTACCAGACAGGGGGAAGCGGACAGCCTGCTCGCAAATCGTCTGCCTATTGTTATCAGGGAAGCGGTTCGTACCCGGACA
GTCACCCAAAAGAAAAAAGGGATTGCCGGTTGGTTCGGAGGGAAAAGGAGCGTACAGGTCTTCGAGCCATCGAAAGGACT
GCAAGATTTGAATGAGAAGCTGATCGCCATGCAAGAGGAACGTGAACGCCGGATAGACATGTATACCGACAGTCTGCGCA
TACAGAATAAGGCCTTGAACCGGAAGTTGCAAATACTCATCACCCATCTTGACGGGCAAGCGCAGGCGGCGTTCATCAGT
CGTGAGGAAAAAATCACGGAAGCCGGAGATTTTTCTTTCAAACTGTTTGTCTTGGTAATCGTCTCTGCTTCCTCCTTGCT
ATTCATCTCGTTCCTGATCATACGGCATGACATCAGGAAAGAAAGGGAAGGGCGGGCACAGCTCCAAAGGATAAACCGTG
AGAACGAGGAACTGCTCGGTATGCGTAAACAGATCATCCTGACCATCTCGCACGATATACGAGGACCATTGGGTAATATC
AACAACTGCGTGGAACTGGCCTCGGAAACCCGTGAAAAGAAAAAACGGGAAGGCTATCTGGAGAACATCCGCCATTCCTG
CCGCCATATACTGAATCTGGTGAACAACCTGATGGATGTTTATAAGATCAATGAGACCAAGGATACCCGTAACGAGGTTC
CTTTCCGTCTAAACAACTTGCTTGACAACATATCGAAGGAATATGCCCGCAAAGCGGGTGGCCGGGCCTTGCTGTTCGAG
CACCGGCATAAGAATGTCGGTGATATTACAGTGAGAGGAGACGCAGACAAATTGGAACAAATATTGGACAATCTGCTGAC
AAACGCCATCAAGTTCACCCTGTCGGGTACGATCCGTTTCCATACCGAGTACATGGCGGGAAGATTATATGTGGAGGTCG
GTGATACCGGTATCGGTATGGACGAGGAGACATTGGAACGTGTCTTCCGTCCGTTCGAGCGTGCGGCGCAGGAGATAAAC
TCGGAAGGTTTCGGTCTTGGGCTTTTTATCACGAAAGCTCTTGTAAAGGTACTGGACGGAAGCATTGAAGTAGAGAGCCG
ACCAGGTAAAGGTACAACATTCCGCCTGTCGTTTCCCCTTTCGGAAACGACAGGAGAACCGGAAACAGAGGAGCTTCCGG
TACAATCTGCGACAATACTTCCCAAACATGTACTGGTAGTGGATGATGACAGCATCCTTCTGAAAATAACGGAAGACATG
CTCGGGCGCAACGGGGTGGAATGCACGACCTGTCAAAATGCAAAAGAAGCCATTCTAGCACTCGACCGCTTGGATTATGA
TTTGGTATTGACAGATATACAGATGCCCGTGACCGATGGTTTCGGCTTGTTGAGATTACTGCGTAACTCGGATATCGGAA
ATTCCCGTACCGTTCCGGTCGCTGTCATGACGGCACGGGGGGACGGGGACTCGGGCGTGTATATGAAGTCCGGTTTTTGC
GGTTGCATACATAAGCCTTTCTCTTCAAAAGGACTGCTGGCCTTTATCTCCTCCGTTACGGAGGGCAGAAGTGCAGGCAT
GTCTCCGTTCGACTATTCCCGCCTGATGGAAAGTACGGACGACCGTCGTCATATGTTCGGTCTTGTCGCAAAAGAGTCAG
AAAAGGATCTTGCCGAACTGGAGGAGGCTTTAAGAGAAAACGATCGGGAAGCCATGCGGAGGATCGTACATCGGATGGCT
CCGGTCTGGGAGTTGTTAGGGGCCAACGATGTACTGTTCGGTTATCGGAAGCTCCTGCATGACAAGACCTCGAGCGACGA
GACGGTCAGAGAGTACACGATGAGAATTATGAAACAGATACGGTTACTGATAGACGAAGTAAATAATGAATTAAGAAAGA
AAAATGACGGGGATGAAAAAGACTTTATTGATCGTGGAGGACAACCTGATTCTTTGCGATATTCTTGA

Upstream 100 bases:

>100_bases
GCTTCTTCTATATTTTATAAATGAATTATAGATAACTATTACACTGGCTTAACGAATCCGTTACAAATCCTTGGTGGTTT
AAAGTGAGTGTTTACGTAAA

Downstream 100 bases:

>100_bases
GAGATGGCTACAGAAAGCCGGTTACAGGGTATTGACGGCCATAGATGAGCCTTCGGCACGCCGGAAAATCAAGGGGAATA
ACGTGGCGCTGGTACTGACG

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MKIFMVARKVSLQHKVLLGYMILIMAVCGMVSILLYERSRMREIKTETSEIRRIRHDISTAHRYITELATYGESVIVWED
TDFREYRRKRLQTDSLLQILKVSCGTFVLPKQIDSLCHLLEAKEIHLLRIMETITRQGEADSLLANRLPIVIREAVRTRT
VTQKKKGIAGWFGGKRSVQVFEPSKGLQDLNEKLIAMQEERERRIDMYTDSLRIQNKALNRKLQILITHLDGQAQAAFIS
REEKITEAGDFSFKLFVLVIVSASSLLFISFLIIRHDIRKEREGRAQLQRINRENEELLGMRKQIILTISHDIRGPLGNI
NNCVELASETREKKKREGYLENIRHSCRHILNLVNNLMDVYKINETKDTRNEVPFRLNNLLDNISKEYARKAGGRALLFE
HRHKNVGDITVRGDADKLEQILDNLLTNAIKFTLSGTIRFHTEYMAGRLYVEVGDTGIGMDEETLERVFRPFERAAQEIN
SEGFGLGLFITKALVKVLDGSIEVESRPGKGTTFRLSFPLSETTGEPETEELPVQSATILPKHVLVVDDDSILLKITEDM
LGRNGVECTTCQNAKEAILALDRLDYDLVLTDIQMPVTDGFGLLRLLRNSDIGNSRTVPVAVMTARGDGDSGVYMKSGFC
GCIHKPFSSKGLLAFISSVTEGRSAGMSPFDYSRLMESTDDRRHMFGLVAKESEKDLAELEEALRENDREAMRRIVHRMA
PVWELLGANDVLFGYRKLLHDKTSSDETVREYTMRIMKQIRLLIDEVNNELRKKNDGDEKDFIDRGGQPDSLRYS

Sequences:

>Translated_795_residues
MKIFMVARKVSLQHKVLLGYMILIMAVCGMVSILLYERSRMREIKTETSEIRRIRHDISTAHRYITELATYGESVIVWED
TDFREYRRKRLQTDSLLQILKVSCGTFVLPKQIDSLCHLLEAKEIHLLRIMETITRQGEADSLLANRLPIVIREAVRTRT
VTQKKKGIAGWFGGKRSVQVFEPSKGLQDLNEKLIAMQEERERRIDMYTDSLRIQNKALNRKLQILITHLDGQAQAAFIS
REEKITEAGDFSFKLFVLVIVSASSLLFISFLIIRHDIRKEREGRAQLQRINRENEELLGMRKQIILTISHDIRGPLGNI
NNCVELASETREKKKREGYLENIRHSCRHILNLVNNLMDVYKINETKDTRNEVPFRLNNLLDNISKEYARKAGGRALLFE
HRHKNVGDITVRGDADKLEQILDNLLTNAIKFTLSGTIRFHTEYMAGRLYVEVGDTGIGMDEETLERVFRPFERAAQEIN
SEGFGLGLFITKALVKVLDGSIEVESRPGKGTTFRLSFPLSETTGEPETEELPVQSATILPKHVLVVDDDSILLKITEDM
LGRNGVECTTCQNAKEAILALDRLDYDLVLTDIQMPVTDGFGLLRLLRNSDIGNSRTVPVAVMTARGDGDSGVYMKSGFC
GCIHKPFSSKGLLAFISSVTEGRSAGMSPFDYSRLMESTDDRRHMFGLVAKESEKDLAELEEALRENDREAMRRIVHRMA
PVWELLGANDVLFGYRKLLHDKTSSDETVREYTMRIMKQIRLLIDEVNNELRKKNDGDEKDFIDRGGQPDSLRYS
>Mature_795_residues
MKIFMVARKVSLQHKVLLGYMILIMAVCGMVSILLYERSRMREIKTETSEIRRIRHDISTAHRYITELATYGESVIVWED
TDFREYRRKRLQTDSLLQILKVSCGTFVLPKQIDSLCHLLEAKEIHLLRIMETITRQGEADSLLANRLPIVIREAVRTRT
VTQKKKGIAGWFGGKRSVQVFEPSKGLQDLNEKLIAMQEERERRIDMYTDSLRIQNKALNRKLQILITHLDGQAQAAFIS
REEKITEAGDFSFKLFVLVIVSASSLLFISFLIIRHDIRKEREGRAQLQRINRENEELLGMRKQIILTISHDIRGPLGNI
NNCVELASETREKKKREGYLENIRHSCRHILNLVNNLMDVYKINETKDTRNEVPFRLNNLLDNISKEYARKAGGRALLFE
HRHKNVGDITVRGDADKLEQILDNLLTNAIKFTLSGTIRFHTEYMAGRLYVEVGDTGIGMDEETLERVFRPFERAAQEIN
SEGFGLGLFITKALVKVLDGSIEVESRPGKGTTFRLSFPLSETTGEPETEELPVQSATILPKHVLVVDDDSILLKITEDM
LGRNGVECTTCQNAKEAILALDRLDYDLVLTDIQMPVTDGFGLLRLLRNSDIGNSRTVPVAVMTARGDGDSGVYMKSGFC
GCIHKPFSSKGLLAFISSVTEGRSAGMSPFDYSRLMESTDDRRHMFGLVAKESEKDLAELEEALRENDREAMRRIVHRMA
PVWELLGANDVLFGYRKLLHDKTSSDETVREYTMRIMKQIRLLIDEVNNELRKKNDGDEKDFIDRGGQPDSLRYS

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=502, Percent_Identity=24.3027888446215, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI48994928, Length=388, Percent_Identity=27.319587628866, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87081816, Length=470, Percent_Identity=24.6808510638298, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI145693157, Length=282, Percent_Identity=28.0141843971631, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1789149, Length=394, Percent_Identity=24.8730964467005, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790436, Length=310, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=317, Percent_Identity=23.9747634069401, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=25.0965250965251, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=25.5605381165919, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=25.3164556962025, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790299, Length=186, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=29.2792792792793, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=234, Percent_Identity=24.3589743589744, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=246, Percent_Identity=24.390243902439, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 90803; Mature: 90803

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFMVARKVSLQHKVLLGYMILIMAVCGMVSILLYERSRMREIKTETSEIRRIRHDIST
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRYITELATYGESVIVWEDTDFREYRRKRLQTDSLLQILKVSCGTFVLPKQIDSLCHLL
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCEECHHHHHHHHHHH
EAKEIHLLRIMETITRQGEADSLLANRLPIVIREAVRTRTVTQKKKGIAGWFGGKRSVQV
HHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEE
FEPSKGLQDLNEKLIAMQEERERRIDMYTDSLRIQNKALNRKLQILITHLDGQAQAAFIS
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHH
REEKITEAGDFSFKLFVLVIVSASSLLFISFLIIRHDIRKEREGRAQLQRINRENEELLG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MRKQIILTISHDIRGPLGNINNCVELASETREKKKREGYLENIRHSCRHILNLVNNLMDV
HHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKINETKDTRNEVPFRLNNLLDNISKEYARKAGGRALLFEHRHKNVGDITVRGDADKLEQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCHHHHHH
ILDNLLTNAIKFTLSGTIRFHTEYMAGRLYVEVGDTGIGMDEETLERVFRPFERAAQEIN
HHHHHHHHHHHHEEECEEEEEEEHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
SEGFGLGLFITKALVKVLDGSIEVESRPGKGTTFRLSFPLSETTGEPETEELPVQSATIL
CCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCHHCCCCCEEEC
PKHVLVVDDDSILLKITEDMLGRNGVECTTCQNAKEAILALDRLDYDLVLTDIQMPVTDG
CCEEEEECCCCEEEEEEHHHHCCCCCCEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCC
FGLLRLLRNSDIGNSRTVPVAVMTARGDGDSGVYMKSGFCGCIHKPFSSKGLLAFISSVT
HHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHCCCCCCCCHHHHHHHHH
EGRSAGMSPFDYSRLMESTDDRRHMFGLVAKESEKDLAELEEALRENDREAMRRIVHRMA
CCHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
PVWELLGANDVLFGYRKLLHDKTSSDETVREYTMRIMKQIRLLIDEVNNELRKKNDGDEK
HHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DFIDRGGQPDSLRYS
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MKIFMVARKVSLQHKVLLGYMILIMAVCGMVSILLYERSRMREIKTETSEIRRIRHDIST
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRYITELATYGESVIVWEDTDFREYRRKRLQTDSLLQILKVSCGTFVLPKQIDSLCHLL
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCEECHHHHHHHHHHH
EAKEIHLLRIMETITRQGEADSLLANRLPIVIREAVRTRTVTQKKKGIAGWFGGKRSVQV
HHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEE
FEPSKGLQDLNEKLIAMQEERERRIDMYTDSLRIQNKALNRKLQILITHLDGQAQAAFIS
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHH
REEKITEAGDFSFKLFVLVIVSASSLLFISFLIIRHDIRKEREGRAQLQRINRENEELLG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MRKQIILTISHDIRGPLGNINNCVELASETREKKKREGYLENIRHSCRHILNLVNNLMDV
HHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKINETKDTRNEVPFRLNNLLDNISKEYARKAGGRALLFEHRHKNVGDITVRGDADKLEQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCHHHHHH
ILDNLLTNAIKFTLSGTIRFHTEYMAGRLYVEVGDTGIGMDEETLERVFRPFERAAQEIN
HHHHHHHHHHHHEEECEEEEEEEHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
SEGFGLGLFITKALVKVLDGSIEVESRPGKGTTFRLSFPLSETTGEPETEELPVQSATIL
CCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCHHCCCCCEEEC
PKHVLVVDDDSILLKITEDMLGRNGVECTTCQNAKEAILALDRLDYDLVLTDIQMPVTDG
CCEEEEECCCCEEEEEEHHHHCCCCCCEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCC
FGLLRLLRNSDIGNSRTVPVAVMTARGDGDSGVYMKSGFCGCIHKPFSSKGLLAFISSVT
HHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHCCCCCCCCHHHHHHHHH
EGRSAGMSPFDYSRLMESTDDRRHMFGLVAKESEKDLAELEEALRENDREAMRRIVHRMA
CCHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
PVWELLGANDVLFGYRKLLHDKTSSDETVREYTMRIMKQIRLLIDEVNNELRKKNDGDEK
HHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DFIDRGGQPDSLRYS
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]