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The map label for this gene is thrS [H]

Identifier: 150003988

GI number: 150003988

Start: 1900121

End: 1901785

Strand: Reverse

Name: thrS [H]

Synonym: BVU_1422

Alternate gene names: 150003988

Gene position: 1901785-1900121 (Counterclockwise)

Preceding gene: 150003991

Following gene: 150003987

Centisome position: 36.83

GC content: 40.9

Gene sequence:

>1665_bases
ATGTTACAAATCTGTTGCAAAAATAACAATATTTCAAAGAACTTCCCAATCGGAAGCTCACTTTTGGATATTTATAATGG
TTTTAATCTAGATATCCCATACGGACCGGTCAGTGCCAAAGTCAATAACAAAGTAGAAGGACTCAATTACCGGGCCTATA
ATAATAAGGATGTAGAGTTCCTGAACATACTGAATCCTTCAGGAATGCGTACCTATGTCCGTTCTCTCTGCTTCATCTTG
TGCAAAGCGGTGGAGGACTTATACCCTGATGGAAAAATCATGCTTGAACATCCCGTATCTAAAGGATATTATTGCGCCTT
GCAGATAGGACGCGAAACCGGGCTGGATGATGTTTCCCGTATTAAGCAGCGAATGAAAGAGATTGTGGAAGCCAACATCC
CTTTCCACCGTTTTGAATGTCACACAACTGAAGTAGTAGAACTATTCCGCCGGAAAGGAATGATGGACAAAGTTAGACTG
CTTGAAACTTCAGGGGAACTTTACTCCTATTATTATACTTTAGAAGATACCATTGACTACTACTATGGCAGTCTGTTGCC
CAGCACCGGATATATCCGCAAATTCGACATTGTTAAATACTATGACGGCTTGTTGCTGCGAGTCCCCAACCGTCAGAATC
CGGAAATATTGGAGGAAGTAGTAAAACAAGAAAAAATGCTGGAAGTATTCAAAGAGCACCGACGCTGGAATCAGATTTTA
GGTGTGGGTACTGTAGGAGATTTCAATGTGGCCTGTAATGAAGGTTATGCCACCGATCTGATTAATGTGTCTGAAGCCTT
GCAGGAAAAAAAAATTTCCAATATTGCTGATGAGATATACCACAGAGGAAAAAACGGTCAAAGAGTAAAACTGGTTCTTA
TCTCCGGTCCATCCTCTTCTGGTAAAACGACTTTCAGCAAACGACTCAGTATCCAGTTGATGGCAAACGGGCTGAAACCT
TACCCCATCTCCCTGGACAATTACTTTGTTGACCGAGAAAAGACACCAAAAGATGAAAAAGGTGATTATGATTACGAATC
ATTGTATGCATTGGATTTGGAGTTCTTCAACAAGCAATTACAAGATCTGCTTCATGGAAAGGAAGTAGAGTTACCACGTT
TCAACTTCACCACAGGAAGAAGGGAATTTAAAGGTGACAAACTTAAGATTGACGATAACATGATATTGATTCTCGAAGGG
ATTCATGCACTTAACCCCGAATTAACCCCTCATATTCCCGCCGAGAATAAATATAAAATATATGTATCGGCATTAACCAC
TATTCTGCTGGACAATCATAATTATATTCCGACTACCGACAACCGTTTGTTGCGCCGTATTATCCGCGATTACAAATACC
GTGGCTATTCCGCAGAGGAAACAATCAGAAGATGGCCCAGCGTACGCGCCGGAGAAGAAAAATGGATCTTCCCATATCAG
GAAAATGCAGATGCCATGTTCAATTCTGCCCTGTTGTTTGAACTGGCCATTATGAAGGATTATGCCATTCCTATTCTAAG
GAATGTTCCCAATAACAAACCGGAATATTCAGAAGCATACCGTTTACGCAAATTCTTGGAATATTTCGCTTCGGTACAAG
ATAAAGAATTGCCTCCCACTTCTTTACTGAGAGAGTTTTTAGGAGGAAGCAGTTTCCGGTATTAA

Upstream 100 bases:

>100_bases
AATACTCCATCTTTAATTAATTTGGTAGGAATTGGCTAATCTCCCTTTTATTCAGTAAATTTCAAGCCGTTTCACTACAT
TAGTAATAATTATTACGATT

Downstream 100 bases:

>100_bases
CCTGTTATTAAACAGTATATAAGTTTTGTTTATGTGCAAAACAAACAGTAATTTCGGCCATTATTAAACAAGTATAAGTG
AATGCACTCCAAAGGCTATA

Product: uridine kinase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MLQICCKNNNISKNFPIGSSLLDIYNGFNLDIPYGPVSAKVNNKVEGLNYRAYNNKDVEFLNILNPSGMRTYVRSLCFIL
CKAVEDLYPDGKIMLEHPVSKGYYCALQIGRETGLDDVSRIKQRMKEIVEANIPFHRFECHTTEVVELFRRKGMMDKVRL
LETSGELYSYYYTLEDTIDYYYGSLLPSTGYIRKFDIVKYYDGLLLRVPNRQNPEILEEVVKQEKMLEVFKEHRRWNQIL
GVGTVGDFNVACNEGYATDLINVSEALQEKKISNIADEIYHRGKNGQRVKLVLISGPSSSGKTTFSKRLSIQLMANGLKP
YPISLDNYFVDREKTPKDEKGDYDYESLYALDLEFFNKQLQDLLHGKEVELPRFNFTTGRREFKGDKLKIDDNMILILEG
IHALNPELTPHIPAENKYKIYVSALTTILLDNHNYIPTTDNRLLRRIIRDYKYRGYSAEETIRRWPSVRAGEEKWIFPYQ
ENADAMFNSALLFELAIMKDYAIPILRNVPNNKPEYSEAYRLRKFLEYFASVQDKELPPTSLLREFLGGSSFRY

Sequences:

>Translated_554_residues
MLQICCKNNNISKNFPIGSSLLDIYNGFNLDIPYGPVSAKVNNKVEGLNYRAYNNKDVEFLNILNPSGMRTYVRSLCFIL
CKAVEDLYPDGKIMLEHPVSKGYYCALQIGRETGLDDVSRIKQRMKEIVEANIPFHRFECHTTEVVELFRRKGMMDKVRL
LETSGELYSYYYTLEDTIDYYYGSLLPSTGYIRKFDIVKYYDGLLLRVPNRQNPEILEEVVKQEKMLEVFKEHRRWNQIL
GVGTVGDFNVACNEGYATDLINVSEALQEKKISNIADEIYHRGKNGQRVKLVLISGPSSSGKTTFSKRLSIQLMANGLKP
YPISLDNYFVDREKTPKDEKGDYDYESLYALDLEFFNKQLQDLLHGKEVELPRFNFTTGRREFKGDKLKIDDNMILILEG
IHALNPELTPHIPAENKYKIYVSALTTILLDNHNYIPTTDNRLLRRIIRDYKYRGYSAEETIRRWPSVRAGEEKWIFPYQ
ENADAMFNSALLFELAIMKDYAIPILRNVPNNKPEYSEAYRLRKFLEYFASVQDKELPPTSLLREFLGGSSFRY
>Mature_554_residues
MLQICCKNNNISKNFPIGSSLLDIYNGFNLDIPYGPVSAKVNNKVEGLNYRAYNNKDVEFLNILNPSGMRTYVRSLCFIL
CKAVEDLYPDGKIMLEHPVSKGYYCALQIGRETGLDDVSRIKQRMKEIVEANIPFHRFECHTTEVVELFRRKGMMDKVRL
LETSGELYSYYYTLEDTIDYYYGSLLPSTGYIRKFDIVKYYDGLLLRVPNRQNPEILEEVVKQEKMLEVFKEHRRWNQIL
GVGTVGDFNVACNEGYATDLINVSEALQEKKISNIADEIYHRGKNGQRVKLVLISGPSSSGKTTFSKRLSIQLMANGLKP
YPISLDNYFVDREKTPKDEKGDYDYESLYALDLEFFNKQLQDLLHGKEVELPRFNFTTGRREFKGDKLKIDDNMILILEG
IHALNPELTPHIPAENKYKIYVSALTTILLDNHNYIPTTDNRLLRRIIRDYKYRGYSAEETIRRWPSVRAGEEKWIFPYQ
ENADAMFNSALLFELAIMKDYAIPILRNVPNNKPEYSEAYRLRKFLEYFASVQDKELPPTSLLREFLGGSSFRY

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 64376; Mature: 64376

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQICCKNNNISKNFPIGSSLLDIYNGFNLDIPYGPVSAKVNNKVEGLNYRAYNNKDVEF
CEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEE
LNILNPSGMRTYVRSLCFILCKAVEDLYPDGKIMLEHPVSKGYYCALQIGRETGLDDVSR
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHH
IKQRMKEIVEANIPFHRFECHTTEVVELFRRKGMMDKVRLLETSGELYSYYYTLEDTIDY
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEHHHHHHH
YYGSLLPSTGYIRKFDIVKYYDGLLLRVPNRQNPEILEEVVKQEKMLEVFKEHRRWNQIL
HHHHHCCCCCCEEEEHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
GVGTVGDFNVACNEGYATDLINVSEALQEKKISNIADEIYHRGKNGQRVKLVLISGPSSS
EECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
GKTTFSKRLSIQLMANGLKPYPISLDNYFVDREKTPKDEKGDYDYESLYALDLEFFNKQL
CCCHHHHHEEEEEEECCCCCCEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QDLLHGKEVELPRFNFTTGRREFKGDKLKIDDNMILILEGIHALNPELTPHIPAENKYKI
HHHHCCCCCCCCCCCCCCCCHHCCCCEEEECCCEEEEEECHHHCCCCCCCCCCCCCCEEE
YVSALTTILLDNHNYIPTTDNRLLRRIIRDYKYRGYSAEETIRRWPSVRAGEEKWIFPYQ
EHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEECCCC
ENADAMFNSALLFELAIMKDYAIPILRNVPNNKPEYSEAYRLRKFLEYFASVQDKELPPT
CCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
SLLREFLGGSSFRY
HHHHHHHCCCCCCC
>Mature Secondary Structure
MLQICCKNNNISKNFPIGSSLLDIYNGFNLDIPYGPVSAKVNNKVEGLNYRAYNNKDVEF
CEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEE
LNILNPSGMRTYVRSLCFILCKAVEDLYPDGKIMLEHPVSKGYYCALQIGRETGLDDVSR
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHH
IKQRMKEIVEANIPFHRFECHTTEVVELFRRKGMMDKVRLLETSGELYSYYYTLEDTIDY
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEHHHHHHH
YYGSLLPSTGYIRKFDIVKYYDGLLLRVPNRQNPEILEEVVKQEKMLEVFKEHRRWNQIL
HHHHHCCCCCCEEEEHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
GVGTVGDFNVACNEGYATDLINVSEALQEKKISNIADEIYHRGKNGQRVKLVLISGPSSS
EECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
GKTTFSKRLSIQLMANGLKPYPISLDNYFVDREKTPKDEKGDYDYESLYALDLEFFNKQL
CCCHHHHHEEEEEEECCCCCCEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QDLLHGKEVELPRFNFTTGRREFKGDKLKIDDNMILILEGIHALNPELTPHIPAENKYKI
HHHHCCCCCCCCCCCCCCCCHHCCCCEEEECCCEEEEEECHHHCCCCCCCCCCCCCCEEE
YVSALTTILLDNHNYIPTTDNRLLRRIIRDYKYRGYSAEETIRRWPSVRAGEEKWIFPYQ
EHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCEECCCC
ENADAMFNSALLFELAIMKDYAIPILRNVPNNKPEYSEAYRLRKFLEYFASVQDKELPPT
CCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
SLLREFLGGSSFRY
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA