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The map label for this gene is murG

Identifier: 150003963

GI number: 150003963

Start: 1869645

End: 1870775

Strand: Reverse

Name: murG

Synonym: BVU_1397

Alternate gene names: 150003963

Gene position: 1870775-1869645 (Counterclockwise)

Preceding gene: 150003964

Following gene: 150003962

Centisome position: 36.23

GC content: 48.36

Gene sequence:

>1131_bases
ATGGAAGAAAATTTAAGAATCATCATCAGCGGAGGAGGAACCGGGGGACACATTTTCCCCGCAGTCTCTATTGCCAACGC
CATCAAGGAACAACATCCCGAAGCGGAAATCCTGTTCGTAGGCGCTGAAGGCAGAATGGAGATGCAACGCGTTCCTGCTG
CCGGATACCCTATAAAAGGATTACCTGTTGCCGGATTCGACCGTAAGAACTTATTGAAAAATGTTTCGGTTCTTTTCAAA
TTGGTCAAAAGCCAGCTATTGGCACGTAAAATCATCAAGGATTTCAAGCCACATGCAGCAGTAGGTGTAGGCGGATATGC
CAGCGGTCCTACTTTGAAAATGGCCGGGATGATGGGTATTCCGACACTGATACAAGAGCAGAACTCTTATGCCGGAGTAA
CCAACAAACTATTGGCAAAGAAAGCCTGCAAAATATGCGTGGCATACGACGGCATGGAACGTTTCTTTGAAAAAGACAAG
ATTATCCTGACCGGAAACCCTGTCCGCCAAGGACTGCGCAACCATCACATCAGCCGTGAAGAGGCTATCCGCTCCTTCGG
GCTGGACCCATCCAAGAAAACAATCCTGATTGTAGGAGGAAGCTTGGGAGCACGCACCATCAACAACTGCGTGATGGAAG
GTTTGGACAAGATTAAAGCATCCGGCGCGCAGTTTATCTGGCAAACCGGGAAAATATATATCGGCGAAGCACGCGCCGCA
GTAGCCCAGGCCGGTGAGTTACCAATGCTCCACGTAACCGATTTTATCAGCGATATGGCCGCCGCATACAGTGCTGCCGA
TTTAATAATCAGCCGTGCCGGAGCAGGTTCCATCTCCGAGTTCTGTTTGTTGCAGAAACCCGTCATTCTGGTTCCGTCAC
CTAATGTGGCCGAAGATCATCAGACCAAGAACGCACTGGCGCTGGTCAATAAAAACGCAGCACTCTATATCAAGGACGCC
GCTGCCAAAGAAGCTCTGCTGGACAAAGCGGTTGAAACCGTGAAACAGCCGGAAACATTGAAAAGTTTAAGTACAAATAT
TGCTAAATTAGCCTTTACCGACTCAGCCAACGTTATTGCCCGGGAGGTATTCAAACTGGCTGATAAATACAGAAAAGAAA
ATGGACGTTAA

Upstream 100 bases:

>100_bases
GCAGCCGGGAAGCGGGAGCCGGAAGAAGAAATATAATATAAACCATTCATTTTAAAAGTATTATTTATACTTTTGCGAAT
AATTCGACTAAAAAGGAATT

Downstream 100 bases:

>100_bases
CACATTAAAATCAGTTTATTTCATCGGTGCCGGAGGTATCGGCATGAGCGCATTGGTACGCTACTTCCTGTCAAAAGGCA
AGAAGGTAGGCGGATATGAC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MEENLRIIISGGGTGGHIFPAVSIANAIKEQHPEAEILFVGAEGRMEMQRVPAAGYPIKGLPVAGFDRKNLLKNVSVLFK
LVKSQLLARKIIKDFKPHAAVGVGGYASGPTLKMAGMMGIPTLIQEQNSYAGVTNKLLAKKACKICVAYDGMERFFEKDK
IILTGNPVRQGLRNHHISREEAIRSFGLDPSKKTILIVGGSLGARTINNCVMEGLDKIKASGAQFIWQTGKIYIGEARAA
VAQAGELPMLHVTDFISDMAAAYSAADLIISRAGAGSISEFCLLQKPVILVPSPNVAEDHQTKNALALVNKNAALYIKDA
AAKEALLDKAVETVKQPETLKSLSTNIAKLAFTDSANVIAREVFKLADKYRKENGR

Sequences:

>Translated_376_residues
MEENLRIIISGGGTGGHIFPAVSIANAIKEQHPEAEILFVGAEGRMEMQRVPAAGYPIKGLPVAGFDRKNLLKNVSVLFK
LVKSQLLARKIIKDFKPHAAVGVGGYASGPTLKMAGMMGIPTLIQEQNSYAGVTNKLLAKKACKICVAYDGMERFFEKDK
IILTGNPVRQGLRNHHISREEAIRSFGLDPSKKTILIVGGSLGARTINNCVMEGLDKIKASGAQFIWQTGKIYIGEARAA
VAQAGELPMLHVTDFISDMAAAYSAADLIISRAGAGSISEFCLLQKPVILVPSPNVAEDHQTKNALALVNKNAALYIKDA
AAKEALLDKAVETVKQPETLKSLSTNIAKLAFTDSANVIAREVFKLADKYRKENGR
>Mature_376_residues
MEENLRIIISGGGTGGHIFPAVSIANAIKEQHPEAEILFVGAEGRMEMQRVPAAGYPIKGLPVAGFDRKNLLKNVSVLFK
LVKSQLLARKIIKDFKPHAAVGVGGYASGPTLKMAGMMGIPTLIQEQNSYAGVTNKLLAKKACKICVAYDGMERFFEKDK
IILTGNPVRQGLRNHHISREEAIRSFGLDPSKKTILIVGGSLGARTINNCVMEGLDKIKASGAQFIWQTGKIYIGEARAA
VAQAGELPMLHVTDFISDMAAAYSAADLIISRAGAGSISEFCLLQKPVILVPSPNVAEDHQTKNALALVNKNAALYIKDA
AAKEALLDKAVETVKQPETLKSLSTNIAKLAFTDSANVIAREVFKLADKYRKENGR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=371, Percent_Identity=32.6145552560647, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_BACV8 (A6L071)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298707.1
- ProteinModelPortal:   A6L071
- SMR:   A6L071
- STRING:   A6L071
- GeneID:   5302363
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1397
- NMPDR:   fig|435590.6.peg.1319
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40465; Mature: 40465

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENLRIIISGGGTGGHIFPAVSIANAIKEQHPEAEILFVGAEGRMEMQRVPAAGYPIKG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCCC
LPVAGFDRKNLLKNVSVLFKLVKSQLLARKIIKDFKPHAAVGVGGYASGPTLKMAGMMGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCC
PTLIQEQNSYAGVTNKLLAKKACKICVAYDGMERFFEKDKIILTGNPVRQGLRNHHISRE
CHHHHCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHCCCCEEEECCHHHHHHHHCCCCHH
EAIRSFGLDPSKKTILIVGGSLGARTINNCVMEGLDKIKASGAQFIWQTGKIYIGEARAA
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHH
VAQAGELPMLHVTDFISDMAAAYSAADLIISRAGAGSISEFCLLQKPVILVPSPNVAEDH
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCCCC
QTKNALALVNKNAALYIKDAAAKEALLDKAVETVKQPETLKSLSTNIAKLAFTDSANVIA
CCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCHHHHH
REVFKLADKYRKENGR
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEENLRIIISGGGTGGHIFPAVSIANAIKEQHPEAEILFVGAEGRMEMQRVPAAGYPIKG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCCC
LPVAGFDRKNLLKNVSVLFKLVKSQLLARKIIKDFKPHAAVGVGGYASGPTLKMAGMMGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCC
PTLIQEQNSYAGVTNKLLAKKACKICVAYDGMERFFEKDKIILTGNPVRQGLRNHHISRE
CHHHHCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHCCCCEEEECCHHHHHHHHCCCCHH
EAIRSFGLDPSKKTILIVGGSLGARTINNCVMEGLDKIKASGAQFIWQTGKIYIGEARAA
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHH
VAQAGELPMLHVTDFISDMAAAYSAADLIISRAGAGSISEFCLLQKPVILVPSPNVAEDH
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCCCC
QTKNALALVNKNAALYIKDAAAKEALLDKAVETVKQPETLKSLSTNIAKLAFTDSANVIA
CCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCHHHHH
REVFKLADKYRKENGR
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA