Click here to switch to the map view.

The map label for this gene is speA [H]

Identifier: 150003904

GI number: 150003904

Start: 1787652

End: 1789544

Strand: Direct

Name: speA [H]

Synonym: BVU_1337

Alternate gene names: 150003904

Gene position: 1787652-1789544 (Clockwise)

Preceding gene: 150003903

Following gene: 150003905

Centisome position: 34.62

GC content: 44.48

Gene sequence:

>1893_bases
ATGAGAAAATGGCGTATTGAAGATTCGGAAGAACTCTACAACATAACAGGGTGGGGAACTTCGTACTTTGGTATCAATGA
CAAAGGTCATGTAGTGGTAACTCCTCGTAAGGACGGCGTTGAGGTCGATTTGAAAGAATTGGTCGATGAGTTGCAATTGC
GGGATGTGGCAGCTCCTATGCTGGTCCGTTTTCCGGATATTCTGGATAATCGTATTGAAAAAATCGCGAACTGCTTTAAG
CAGGCATCTGATGAGTATGGGTATAAGGCCCAGAATTTTATCATTTATCCTATCAAGGTAAATCAGATGCGTCCTGTAGT
GGAAGAAATCATCAGTCATGGAAAGAAATTCAATTTGGGACTGGAAGCCGGTTCCAAACCTGAACTTCATGCGGTGATAG
CTGTGAATACAGATTCGGATTCATTGATTATCTGCAACGGATATAAGGACGAAAGTTATATCGAGCTGGCTCTGCTGGCA
CAGAAGATGGGGAAACGTATTTTCTTGGTGGTGGAGAAAATGAATGAATTACGCCTGATAGCCAAAATGGCAAAGCAGCT
GAATGTGCGTCCTAACATAGGTATCCGCATTAAGCTGGCTTCTTCGGGAAGTGGTAAATGGGAAGATAGCGGAGGAGATG
CCAGTAAGTTTGGCTTGACATCCAGTGAATTGCTGGAAGCGCTTGATTTTCTGGAAAAGAAAGACATGAAGGACTGTCTG
AAACTGATTCATTTTCATATAGGCAGCCAGGTGACTAAAATACGCCGTATCAAGACAGCTCTGCGTGAGGCATCGCAATT
CTATGTGCAGTTGCATGTGATGGGATTTAATGTGGAATTTGTGGATATCGGCGGCGGTTTGGGTGTGGATTACGACGGAA
CTCGTTCTGCCAATAGTGAAAGCAGTGTGAACTACTCTATTCAGGAGTATGTGAATGACTCTATCTCTACGCTGGTGGAT
GCCAGTGACAAGAATGGAATTCCTCATCCGAATATTATTACCGAAAGCGGACGTTCACTGACCGCCCATCACTCCGTGCT
GATTTTCGAGGTGCTGGAAACGGCGACTTTGCCCGAAATGGATGAGGATTTCGAAGTGGGTGAAAATGATCATGAACTGG
TACATGAACTTTATGAGATTTGGGATAATCTGAATCAGAGCCGTATGGTGGAGGCTTGGCACGATGCACAGCAGATACGT
GAGGAAGCACTTGATTTATTCAGCCACGGTATTGTGGATTTGAAGACCCGTGCCCAGATAGAGCGTCTGTACTGGTCGGT
GACCCGTGAGATCAATCAGATTGCTTCGGGGCTGAAACATGCGCCCGATGAGTTCCGCAAACTGGACAAACTGCTGGCTG
ATAAATATTTTTGTAATTTCTCGTTGTTCCAGTCGTTGCCGGACTCGTGGGCGATAGATCAGATATTCCCTATCATGCCT
ATCCAGCGTCTGGATGAGAAGCCCGACAGAAATGCTACCTTGCAGGATATCACTTGTGATTCGGATGGAAAAATTGCCAA
TTTTATCTCTACCCGTTATGTATCGCATGACCTGCCGGTACATTCGTTGAAGGGAAAAGACGCTTATTATATAGGTGTAT
TTTTGGTTGGTGCTTATCAGGAGATTCTGGGTGATATGCACAATTTGTTTGGAGATACCAATGCGGTGCATGTTACGGTG
GATGACAAAGGGTATTCTATTGATCAGGTAATTGATGGTGAAACGGTGGCCGAGGTTTTGGATTATGTACAATATAACCC
GAAGAAATTGGTGCGTACACTGGAAACCTGGGTGACCAAATCAGTGAAGGAAGGAAGAATTTCTGTAGAGGAAGGAAAAG
AATTCCTCTCTAATTATCGTTCCGGGTTGTACGGATATACTTATTTGGAATAA

Upstream 100 bases:

>100_bases
AGGATAAAAGACAAATTCAAGCCTCTGTTGACAGCTTGAGAAAGAAATTGAATAAATAATTATATATAGTAAAATACACA
CTCTTTGTACAGAAGAAGAA

Downstream 100 bases:

>100_bases
TAGCATGAAAGAGAAACTGACTATCATAAAAGTAGGTGGAAAAATTGTAGAGGAAGAGTCTACACTTAATCAGTTGTTGG
CTGATTTCTCTGCTATAGAA

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MRKWRIEDSEELYNITGWGTSYFGINDKGHVVVTPRKDGVEVDLKELVDELQLRDVAAPMLVRFPDILDNRIEKIANCFK
QASDEYGYKAQNFIIYPIKVNQMRPVVEEIISHGKKFNLGLEAGSKPELHAVIAVNTDSDSLIICNGYKDESYIELALLA
QKMGKRIFLVVEKMNELRLIAKMAKQLNVRPNIGIRIKLASSGSGKWEDSGGDASKFGLTSSELLEALDFLEKKDMKDCL
KLIHFHIGSQVTKIRRIKTALREASQFYVQLHVMGFNVEFVDIGGGLGVDYDGTRSANSESSVNYSIQEYVNDSISTLVD
ASDKNGIPHPNIITESGRSLTAHHSVLIFEVLETATLPEMDEDFEVGENDHELVHELYEIWDNLNQSRMVEAWHDAQQIR
EEALDLFSHGIVDLKTRAQIERLYWSVTREINQIASGLKHAPDEFRKLDKLLADKYFCNFSLFQSLPDSWAIDQIFPIMP
IQRLDEKPDRNATLQDITCDSDGKIANFISTRYVSHDLPVHSLKGKDAYYIGVFLVGAYQEILGDMHNLFGDTNAVHVTV
DDKGYSIDQVIDGETVAEVLDYVQYNPKKLVRTLETWVTKSVKEGRISVEEGKEFLSNYRSGLYGYTYLE

Sequences:

>Translated_630_residues
MRKWRIEDSEELYNITGWGTSYFGINDKGHVVVTPRKDGVEVDLKELVDELQLRDVAAPMLVRFPDILDNRIEKIANCFK
QASDEYGYKAQNFIIYPIKVNQMRPVVEEIISHGKKFNLGLEAGSKPELHAVIAVNTDSDSLIICNGYKDESYIELALLA
QKMGKRIFLVVEKMNELRLIAKMAKQLNVRPNIGIRIKLASSGSGKWEDSGGDASKFGLTSSELLEALDFLEKKDMKDCL
KLIHFHIGSQVTKIRRIKTALREASQFYVQLHVMGFNVEFVDIGGGLGVDYDGTRSANSESSVNYSIQEYVNDSISTLVD
ASDKNGIPHPNIITESGRSLTAHHSVLIFEVLETATLPEMDEDFEVGENDHELVHELYEIWDNLNQSRMVEAWHDAQQIR
EEALDLFSHGIVDLKTRAQIERLYWSVTREINQIASGLKHAPDEFRKLDKLLADKYFCNFSLFQSLPDSWAIDQIFPIMP
IQRLDEKPDRNATLQDITCDSDGKIANFISTRYVSHDLPVHSLKGKDAYYIGVFLVGAYQEILGDMHNLFGDTNAVHVTV
DDKGYSIDQVIDGETVAEVLDYVQYNPKKLVRTLETWVTKSVKEGRISVEEGKEFLSNYRSGLYGYTYLE
>Mature_630_residues
MRKWRIEDSEELYNITGWGTSYFGINDKGHVVVTPRKDGVEVDLKELVDELQLRDVAAPMLVRFPDILDNRIEKIANCFK
QASDEYGYKAQNFIIYPIKVNQMRPVVEEIISHGKKFNLGLEAGSKPELHAVIAVNTDSDSLIICNGYKDESYIELALLA
QKMGKRIFLVVEKMNELRLIAKMAKQLNVRPNIGIRIKLASSGSGKWEDSGGDASKFGLTSSELLEALDFLEKKDMKDCL
KLIHFHIGSQVTKIRRIKTALREASQFYVQLHVMGFNVEFVDIGGGLGVDYDGTRSANSESSVNYSIQEYVNDSISTLVD
ASDKNGIPHPNIITESGRSLTAHHSVLIFEVLETATLPEMDEDFEVGENDHELVHELYEIWDNLNQSRMVEAWHDAQQIR
EEALDLFSHGIVDLKTRAQIERLYWSVTREINQIASGLKHAPDEFRKLDKLLADKYFCNFSLFQSLPDSWAIDQIFPIMP
IQRLDEKPDRNATLQDITCDSDGKIANFISTRYVSHDLPVHSLKGKDAYYIGVFLVGAYQEILGDMHNLFGDTNAVHVTV
DDKGYSIDQVIDGETVAEVLDYVQYNPKKLVRTLETWVTKSVKEGRISVEEGKEFLSNYRSGLYGYTYLE

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=633, Percent_Identity=44.391785150079, Blast_Score=538, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71489; Mature: 71489

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKWRIEDSEELYNITGWGTSYFGINDKGHVVVTPRKDGVEVDLKELVDELQLRDVAAPM
CCCCCCCCHHHEEEEECCCCEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LVRFPDILDNRIEKIANCFKQASDEYGYKAQNFIIYPIKVNQMRPVVEEIISHGKKFNLG
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEEEECHHHHHHHHHHHCCCEEEEE
LEAGSKPELHAVIAVNTDSDSLIICNGYKDESYIELALLAQKMGKRIFLVVEKMNELRLI
CCCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHH
AKMAKQLNVRPNIGIRIKLASSGSGKWEDSGGDASKFGLTSSELLEALDFLEKKDMKDCL
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCHHHHH
KLIHFHIGSQVTKIRRIKTALREASQFYVQLHVMGFNVEFVDIGGGLGVDYDGTRSANSE
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCC
SSVNYSIQEYVNDSISTLVDASDKNGIPHPNIITESGRSLTAHHSVLIFEVLETATLPEM
CCCCEEHHHHHCHHHHHHHCCCCCCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHCCCCC
DEDFEVGENDHELVHELYEIWDNLNQSRMVEAWHDAQQIREEALDLFSHGIVDLKTRAQI
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHH
ERLYWSVTREINQIASGLKHAPDEFRKLDKLLADKYFCNFSLFQSLPDSWAIDQIFPIMP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHCCCC
IQRLDEKPDRNATLQDITCDSDGKIANFISTRYVSHDLPVHSLKGKDAYYIGVFLVGAYQ
HHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHH
EILGDMHNLFGDTNAVHVTVDDKGYSIDQVIDGETVAEVLDYVQYNPKKLVRTLETWVTK
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
SVKEGRISVEEGKEFLSNYRSGLYGYTYLE
HHHCCCCCHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MRKWRIEDSEELYNITGWGTSYFGINDKGHVVVTPRKDGVEVDLKELVDELQLRDVAAPM
CCCCCCCCHHHEEEEECCCCEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LVRFPDILDNRIEKIANCFKQASDEYGYKAQNFIIYPIKVNQMRPVVEEIISHGKKFNLG
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEEEECHHHHHHHHHHHCCCEEEEE
LEAGSKPELHAVIAVNTDSDSLIICNGYKDESYIELALLAQKMGKRIFLVVEKMNELRLI
CCCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHH
AKMAKQLNVRPNIGIRIKLASSGSGKWEDSGGDASKFGLTSSELLEALDFLEKKDMKDCL
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCHHHHH
KLIHFHIGSQVTKIRRIKTALREASQFYVQLHVMGFNVEFVDIGGGLGVDYDGTRSANSE
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCC
SSVNYSIQEYVNDSISTLVDASDKNGIPHPNIITESGRSLTAHHSVLIFEVLETATLPEM
CCCCEEHHHHHCHHHHHHHCCCCCCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHCCCCC
DEDFEVGENDHELVHELYEIWDNLNQSRMVEAWHDAQQIREEALDLFSHGIVDLKTRAQI
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHH
ERLYWSVTREINQIASGLKHAPDEFRKLDKLLADKYFCNFSLFQSLPDSWAIDQIFPIMP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHCCCC
IQRLDEKPDRNATLQDITCDSDGKIANFISTRYVSHDLPVHSLKGKDAYYIGVFLVGAYQ
HHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHH
EILGDMHNLFGDTNAVHVTVDDKGYSIDQVIDGETVAEVLDYVQYNPKKLVRTLETWVTK
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
SVKEGRISVEEGKEFLSNYRSGLYGYTYLE
HHHCCCCCHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA