Click here to switch to the map view.

The map label for this gene is aroK

Identifier: 150003903

GI number: 150003903

Start: 1787083

End: 1787610

Strand: Direct

Name: aroK

Synonym: BVU_1336

Alternate gene names: 150003903

Gene position: 1787083-1787610 (Clockwise)

Preceding gene: 150003902

Following gene: 150003904

Centisome position: 34.61

GC content: 42.99

Gene sequence:

>528_bases
ATGACACGTATATTTTTAATAGGATATATGGGCGCGGGCAAAACGACTCTAGGTAAGGCGTTTGCCCGTGAAATGAGTCT
GAATTTCATTGATTTGGACTGGTTTATCGAGGAACGTTTCCATAAAACCGTTCAACAGCTGTTCTTGGAACGCGGAGAAG
ACGGATTCCGGGAACTGGAACGGAAAATGTTGCACGAAGTGGCCGAGTTTGAAGATGTGGTTGTTTCGACCGGTGGAGGA
ACACCTTGTTTTTTTGATAACATGGAGTATATGAATGATTGCGGTGATACGGTGTTTCTGGATGTGGAACCTGCCGTATT
GTTCCGCCGTCTGAGAGTGGCCAAGCAGCAACGTCCATTGTTAGCAAATAAAAGTGATGAGGAACTGATGGATTTTATCT
GTGAGGCGTTACAGAAAAGACATCCGTTTTATTCAAAGGCGAAACATCTGTTTAAGGCTGATGAGCTGGAGGATAAAAGA
CAAATTCAAGCCTCTGTTGACAGCTTGAGAAAGAAATTGAATAAATAA

Upstream 100 bases:

>100_bases
ACAGGGGAACCGTGAATATGGAAGAGGAGTCCGAAAAGCCCGAAGAATCCGCAAAAAGTAAGGCGGCTTCCAAGGTAAAG
GGCACTGCAAAAGCAAAAAA

Downstream 100 bases:

>100_bases
TTATATATAGTAAAATACACACTCTTTGTACAGAAGAAGAAATGAGAAAATGGCGTATTGAAGATTCGGAAGAACTCTAC
AACATAACAGGGTGGGGAAC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTRIFLIGYMGAGKTTLGKAFAREMSLNFIDLDWFIEERFHKTVQQLFLERGEDGFRELERKMLHEVAEFEDVVVSTGGG
TPCFFDNMEYMNDCGDTVFLDVEPAVLFRRLRVAKQQRPLLANKSDEELMDFICEALQKRHPFYSKAKHLFKADELEDKR
QIQASVDSLRKKLNK

Sequences:

>Translated_175_residues
MTRIFLIGYMGAGKTTLGKAFAREMSLNFIDLDWFIEERFHKTVQQLFLERGEDGFRELERKMLHEVAEFEDVVVSTGGG
TPCFFDNMEYMNDCGDTVFLDVEPAVLFRRLRVAKQQRPLLANKSDEELMDFICEALQKRHPFYSKAKHLFKADELEDKR
QIQASVDSLRKKLNK
>Mature_174_residues
TRIFLIGYMGAGKTTLGKAFAREMSLNFIDLDWFIEERFHKTVQQLFLERGEDGFRELERKMLHEVAEFEDVVVSTGGGT
PCFFDNMEYMNDCGDTVFLDVEPAVLFRRLRVAKQQRPLLANKSDEELMDFICEALQKRHPFYSKAKHLFKADELEDKRQ
IQASVDSLRKKLNK

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=142, Percent_Identity=33.0985915492958, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786587, Length=173, Percent_Identity=30.0578034682081, Blast_Score=77, Evalue=5e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_BACV8 (A6L011)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298647.1
- ProteinModelPortal:   A6L011
- SMR:   A6L011
- STRING:   A6L011
- GeneID:   5302302
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1336
- NMPDR:   fig|435590.6.peg.1258
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VEKEGWE
- ProtClustDB:   PRK13949
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20453; Mature: 20322

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 33-33 BINDING 57-57 BINDING 79-79 BINDING 118-118 BINDING 140-140

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIFLIGYMGAGKTTLGKAFAREMSLNFIDLDWFIEERFHKTVQQLFLERGEDGFRELE
CCEEEEEEECCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RKMLHEVAEFEDVVVSTGGGTPCFFDNMEYMNDCGDTVFLDVEPAVLFRRLRVAKQQRPL
HHHHHHHHHHHHHEEECCCCCCCEECCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCC
LANKSDEELMDFICEALQKRHPFYSKAKHLFKADELEDKRQIQASVDSLRKKLNK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRIFLIGYMGAGKTTLGKAFAREMSLNFIDLDWFIEERFHKTVQQLFLERGEDGFRELE
CEEEEEEECCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RKMLHEVAEFEDVVVSTGGGTPCFFDNMEYMNDCGDTVFLDVEPAVLFRRLRVAKQQRPL
HHHHHHHHHHHHHEEECCCCCCCEECCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCC
LANKSDEELMDFICEALQKRHPFYSKAKHLFKADELEDKRQIQASVDSLRKKLNK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA