Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 150003715

GI number: 150003715

Start: 1543664

End: 1544245

Strand: Reverse

Name: yggV [C]

Synonym: BVU_1146

Alternate gene names: 150003715

Gene position: 1544245-1543664 (Counterclockwise)

Preceding gene: 150003717

Following gene: 150003712

Centisome position: 29.91

GC content: 41.41

Gene sequence:

>582_bases
ATGAAAAAGAAATTAGTATTTGCTACAAACAATGCTCATAAACTGGATGAAATATCCTCCATTCTAGGAGAAAAAGTTGA
ATTATTGAGTTTGAAAGATATCCATTGCCATGTTGATATCCCCGAAACTGCTGATACGTTGGAAGGCAATGCTATGCTGA
AAGCGGAGTATATTTATAAAAACTACGGTTTAGACTGTTTTGCCGACGATACAGGCCTGGAAGTGGAAGCTTTGAATGGT
GCTCCGGGTGTTTATTCCGCCCGTTATGCCGGAGGCGAAGGACACAATGCGGAAGCCAATATGCAAAAATTATTGCAGAA
TATGCAAGGAGTGCAAAATAGAAAAGCACAATTCCGCACAGCTATCTGCCTGATTCTGGATGGAAAGAAGCATTTGTTCG
AAGGAATTGTAAAAGGTGAGATTATCAAAGAAAAACGAGGTTCGTCAGGTTTCGGATACGACCCTATCTTTGTGCCCGAA
GGATATACTAAAACTTTTGCCGAACTAGGCAATGAGACGAAAAACAAAATCAGTCACCGTGCACTGGCCGTAGAGAAACT
TTGCCGGTTTCTGAAGGCGTAA

Upstream 100 bases:

>100_bases
AACAAATTACTATTTACCTTTTCACCTATATTATTCTGTCAGGAATTATCTTACTTTGGTTCATTCTCAGTATCTTTGCA
TTCAATTAATATGATATAAA

Downstream 100 bases:

>100_bases
CTATATAAATTAGTTATATCATTTGTTTACCTCTATTGAGCCTCATAAAAACAAGTATTCTGTTTTCCTTTGAAAACAAT
TTTGACGGAATAATGATTTC

Product: putative deoxyribonucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKKKLVFATNNAHKLDEISSILGEKVELLSLKDIHCHVDIPETADTLEGNAMLKAEYIYKNYGLDCFADDTGLEVEALNG
APGVYSARYAGGEGHNAEANMQKLLQNMQGVQNRKAQFRTAICLILDGKKHLFEGIVKGEIIKEKRGSSGFGYDPIFVPE
GYTKTFAELGNETKNKISHRALAVEKLCRFLKA

Sequences:

>Translated_193_residues
MKKKLVFATNNAHKLDEISSILGEKVELLSLKDIHCHVDIPETADTLEGNAMLKAEYIYKNYGLDCFADDTGLEVEALNG
APGVYSARYAGGEGHNAEANMQKLLQNMQGVQNRKAQFRTAICLILDGKKHLFEGIVKGEIIKEKRGSSGFGYDPIFVPE
GYTKTFAELGNETKNKISHRALAVEKLCRFLKA
>Mature_193_residues
MKKKLVFATNNAHKLDEISSILGEKVELLSLKDIHCHVDIPETADTLEGNAMLKAEYIYKNYGLDCFADDTGLEVEALNG
APGVYSARYAGGEGHNAEANMQKLLQNMQGVQNRKAQFRTAICLILDGKKHLFEGIVKGEIIKEKRGSSGFGYDPIFVPE
GYTKTFAELGNETKNKISHRALAVEKLCRFLKA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=188, Percent_Identity=30.3191489361702, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=38.7755102040816, Blast_Score=118, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17556833, Length=201, Percent_Identity=29.3532338308458, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=196, Percent_Identity=33.1632653061224, Blast_Score=94, Evalue=9e-21,
Organism=Drosophila melanogaster, GI19920712, Length=192, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21352; Mature: 21352

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLVFATNNAHKLDEISSILGEKVELLSLKDIHCHVDIPETADTLEGNAMLKAEYIYK
CCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEEEEEEEECCCCCHHCCCCEEEEEEEHHH
NYGLDCFADDTGLEVEALNGAPGVYSARYAGGEGHNAEANMQKLLQNMQGVQNRKAQFRT
HCCCEEEECCCCCEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
AICLILDGKKHLFEGIVKGEIIKEKRGSSGFGYDPIFVPEGYTKTFAELGNETKNKISHR
EEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHCCHHHHHHHHH
ALAVEKLCRFLKA
HHHHHHHHHHHCC
>Mature Secondary Structure
MKKKLVFATNNAHKLDEISSILGEKVELLSLKDIHCHVDIPETADTLEGNAMLKAEYIYK
CCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEEEEEEEECCCCCHHCCCCEEEEEEEHHH
NYGLDCFADDTGLEVEALNGAPGVYSARYAGGEGHNAEANMQKLLQNMQGVQNRKAQFRT
HCCCEEEECCCCCEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
AICLILDGKKHLFEGIVKGEIIKEKRGSSGFGYDPIFVPEGYTKTFAELGNETKNKISHR
EEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHCCHHHHHHHHH
ALAVEKLCRFLKA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]