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The map label for this gene is argS

Identifier: 150003650

GI number: 150003650

Start: 1436076

End: 1437896

Strand: Reverse

Name: argS

Synonym: BVU_1081

Alternate gene names: 150003650

Gene position: 1437896-1436076 (Counterclockwise)

Preceding gene: 150003653

Following gene: 150003649

Centisome position: 27.85

GC content: 43.33

Gene sequence:

>1821_bases
ATGAATATAGAAGAAAAACTCACCACGTCCATTATCAGCGCTATCAAAACGTTGTACGGACAGGATGTACCCGGAAAAAT
GGTACAACTGCAAAAGACTAAGAAAGAGTTTGAAGGACATCTTACTTTGGTTGTTTTCCCTTTTCTGAAAATGTCTAAGA
AGGGGCCTGAACAGACCGCACAGGAAATAGGCGGATACCTGAAAGAGCATGCTCCCGAATTGGTTTCAGCCTACAATGCA
GTGAAGGGCTTTCTTAATTTGACAATTGCTTCGGATTGTTGGATTGAACTTTTGAATTCTATTCAGGCTGCTCCCGAATA
CGGTATTGAAAAGGCTACGGAAAACTCTCCGTTGGTGATGATTGAGTATTCTTCTCCCAATACAAACAAGCCGCTTCATC
TGGGGCACGTCCGTAATAACCTGTTGGGAAATGCCTTGGCAAATGTCATGGCGGCAAATGGCAATAAGGTGGTCAAGACC
AATATTGTGAATGACCGTGGTATCCATATCTGTAAGTCCATGCTGGCCTGGTTGAAATATGGTAACGGTGAAACACCTGA
ATCATCGGGTAAGAAGGGGGACCATTTGATTGGTGACTATTATGTAGCTTTTGACAAGCATTACAAGGCTGAGGTAAAGG
AACTGACAGCTCAGTACCAGGCTGAAGGCTTGAATGAAGAAGAAGCTAAGGCTAAGGCAGAGGCAAACTCTCCTCTGATG
CTGGAAGCTCGCGAGATGCTCCGTAAGTGGGAGGCGAATGACCCTGAGATCCGTGCCTTGTGGAAGAAGATGAATGACTG
GGTATATGCCGGATTCGATGAAACGTATAAGATGATGGGAGTTAGTTTCGATAAAATTTATTATGAATCGAATACCTATC
TGGAAGGTAAGGAGAAAGTGATGGAAGGACTGGAAAAAGGTTTCTTCTACCGGAAAGAGGATAACTCTGTATGGGCTGAT
TTGACTGCCGAAGGACTGGACCATAAGTTGCTTCTTCGCGGTGACGGTACTTCTGTTTATATGACCCAGGATATCGGTAC
TGCCAAATTACGTTTTCAGGATTACCCCATCAACAAGATGATTTATGTAGTGGGTAATGAACAAAACTATCATTTCCAGG
TACTTTCTATCTTGCTCGACAAATTGGGTTTTGAATGGGGCAAAGGATTGGTTCATTTCTCATACGGTATGGTAGAGCTG
CCCGAGGGCAAAATGAAAAGTCGTGAAGGTACAGTAGTGGATGCGGATGATTTGATGGAAGCAATGATTGAAACTGCTAA
GGAAACTTCTGCTGAATTAGGTAAATTGGACGGTCTGACCCAAGAAGAAGCCGACAATATTGCCCGTATTGTTGGTTTGG
GTGCTTTGAAATATTTTATCCTGAAGGTGGACGCACGTAAGAATATGACTTTCAACCCGAAAGAATCGATAGATTTCAAT
GGCAATACAGGACCTTTCATTCAGTATACGTATGCCCGTATCCAGTCTGTATTACGCAAAGCGGCTGAAGCAGGTATCGT
TATTCCCGAAATCATTCCAGCAGGTTTGGAACTGAGCGCAAAAGAAGAAGGTTTGATTCAGATGCTGGCTGATTTTAAAT
CGGTTGTCAAGCAGGCAGGCTCAGACTATAATCCTTCCATTATAGCAAACTATGCATACGATTTGGTGAAAGAATACAAC
CAGTTCTATCATGATTTCAGTATTCTGCGTGAAGAAAACGAAGCGTTGAAAGTCTTCCGTCTGGCATTGAGTGCCAATGT
GGGCAAGATTGTGAAGACAGCAATGGGCTTGCTGGGTATTGAAGTGCCTGAACGTATGTAA

Upstream 100 bases:

>100_bases
TTGCAGAGAGGAGATATAGTAAATTAAGGTAAGATAGGAAGGATTTCGCCTAAAATGTCTATCTTTGCAATCCAATAACA
AATAAGTGTACGTACATATT

Downstream 100 bases:

>100_bases
ATGGCAAAGAAACAGAAATATTATGTAGTATGGAAAGGTGTCAATCCGGGAGTTTATGACTCCTGGACTGACTGCCAGCT
ACAGATAAAAGGTTATGATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MNIEEKLTTSIISAIKTLYGQDVPGKMVQLQKTKKEFEGHLTLVVFPFLKMSKKGPEQTAQEIGGYLKEHAPELVSAYNA
VKGFLNLTIASDCWIELLNSIQAAPEYGIEKATENSPLVMIEYSSPNTNKPLHLGHVRNNLLGNALANVMAANGNKVVKT
NIVNDRGIHICKSMLAWLKYGNGETPESSGKKGDHLIGDYYVAFDKHYKAEVKELTAQYQAEGLNEEEAKAKAEANSPLM
LEAREMLRKWEANDPEIRALWKKMNDWVYAGFDETYKMMGVSFDKIYYESNTYLEGKEKVMEGLEKGFFYRKEDNSVWAD
LTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFQDYPINKMIYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVEL
PEGKMKSREGTVVDADDLMEAMIETAKETSAELGKLDGLTQEEADNIARIVGLGALKYFILKVDARKNMTFNPKESIDFN
GNTGPFIQYTYARIQSVLRKAAEAGIVIPEIIPAGLELSAKEEGLIQMLADFKSVVKQAGSDYNPSIIANYAYDLVKEYN
QFYHDFSILREENEALKVFRLALSANVGKIVKTAMGLLGIEVPERM

Sequences:

>Translated_606_residues
MNIEEKLTTSIISAIKTLYGQDVPGKMVQLQKTKKEFEGHLTLVVFPFLKMSKKGPEQTAQEIGGYLKEHAPELVSAYNA
VKGFLNLTIASDCWIELLNSIQAAPEYGIEKATENSPLVMIEYSSPNTNKPLHLGHVRNNLLGNALANVMAANGNKVVKT
NIVNDRGIHICKSMLAWLKYGNGETPESSGKKGDHLIGDYYVAFDKHYKAEVKELTAQYQAEGLNEEEAKAKAEANSPLM
LEAREMLRKWEANDPEIRALWKKMNDWVYAGFDETYKMMGVSFDKIYYESNTYLEGKEKVMEGLEKGFFYRKEDNSVWAD
LTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFQDYPINKMIYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVEL
PEGKMKSREGTVVDADDLMEAMIETAKETSAELGKLDGLTQEEADNIARIVGLGALKYFILKVDARKNMTFNPKESIDFN
GNTGPFIQYTYARIQSVLRKAAEAGIVIPEIIPAGLELSAKEEGLIQMLADFKSVVKQAGSDYNPSIIANYAYDLVKEYN
QFYHDFSILREENEALKVFRLALSANVGKIVKTAMGLLGIEVPERM
>Mature_606_residues
MNIEEKLTTSIISAIKTLYGQDVPGKMVQLQKTKKEFEGHLTLVVFPFLKMSKKGPEQTAQEIGGYLKEHAPELVSAYNA
VKGFLNLTIASDCWIELLNSIQAAPEYGIEKATENSPLVMIEYSSPNTNKPLHLGHVRNNLLGNALANVMAANGNKVVKT
NIVNDRGIHICKSMLAWLKYGNGETPESSGKKGDHLIGDYYVAFDKHYKAEVKELTAQYQAEGLNEEEAKAKAEANSPLM
LEAREMLRKWEANDPEIRALWKKMNDWVYAGFDETYKMMGVSFDKIYYESNTYLEGKEKVMEGLEKGFFYRKEDNSVWAD
LTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFQDYPINKMIYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVEL
PEGKMKSREGTVVDADDLMEAMIETAKETSAELGKLDGLTQEEADNIARIVGLGALKYFILKVDARKNMTFNPKESIDFN
GNTGPFIQYTYARIQSVLRKAAEAGIVIPEIIPAGLELSAKEEGLIQMLADFKSVVKQAGSDYNPSIIANYAYDLVKEYN
QFYHDFSILREENEALKVFRLALSANVGKIVKTAMGLLGIEVPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=502, Percent_Identity=27.2908366533865, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI15149476, Length=588, Percent_Identity=24.4897959183673, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1788184, Length=541, Percent_Identity=27.7264325323475, Blast_Score=175, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI71985061, Length=639, Percent_Identity=23.1611893583725, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985068, Length=608, Percent_Identity=22.5328947368421, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17532153, Length=394, Percent_Identity=22.8426395939086, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320548, Length=509, Percent_Identity=28.4872298624754, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321883, Length=611, Percent_Identity=24.3862520458265, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI28571570, Length=513, Percent_Identity=22.4171539961014, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18859963, Length=588, Percent_Identity=23.2993197278912, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_BACV8 (A6KZA8)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298394.1
- ProteinModelPortal:   A6KZA8
- STRING:   A6KZA8
- GeneID:   5302047
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1081
- NMPDR:   fig|435590.6.peg.1023
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 67999; Mature: 67999

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEEKLTTSIISAIKTLYGQDVPGKMVQLQKTKKEFEGHLTLVVFPFLKMSKKGPEQTA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHH
QEIGGYLKEHAPELVSAYNAVKGFLNLTIASDCWIELLNSIQAAPEYGIEKATENSPLVM
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
IEYSSPNTNKPLHLGHVRNNLLGNALANVMAANGNKVVKTNIVNDRGIHICKSMLAWLKY
EEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GNGETPESSGKKGDHLIGDYYVAFDKHYKAEVKELTAQYQAEGLNEEEAKAKAEANSPLM
CCCCCCCCCCCCCCCEEECEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEE
LEAREMLRKWEANDPEIRALWKKMNDWVYAGFDETYKMMGVSFDKIYYESNTYLEGKEKV
HHHHHHHHHHCCCCHHHHHHHHHHCCCEEECHHHHHHHHCCCHHHEEECCCCEECCHHHH
MEGLEKGFFYRKEDNSVWADLTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFQDYPINKM
HHHHHHCCCEEECCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCEEEEEEECCCCEE
IYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSREGTVVDADDLME
EEEEECCCCCHHHHHHHHHHHHCHHHCCCEEEEECCCEECCCCCCCCCCCCEECHHHHHH
AMIETAKETSAELGKLDGLTQEEADNIARIVGLGALKYFILKVDARKNMTFNPKESIDFN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCC
GNTGPFIQYTYARIQSVLRKAAEAGIVIPEIIPAGLELSAKEEGLIQMLADFKSVVKQAG
CCCCCCCHHHHHHHHHHHHHHHHCCEECHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SDYNPSIIANYAYDLVKEYNQFYHDFSILREENEALKVFRLALSANVGKIVKTAMGLLGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
EVPERM
CCCCCC
>Mature Secondary Structure
MNIEEKLTTSIISAIKTLYGQDVPGKMVQLQKTKKEFEGHLTLVVFPFLKMSKKGPEQTA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCHHHHH
QEIGGYLKEHAPELVSAYNAVKGFLNLTIASDCWIELLNSIQAAPEYGIEKATENSPLVM
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
IEYSSPNTNKPLHLGHVRNNLLGNALANVMAANGNKVVKTNIVNDRGIHICKSMLAWLKY
EEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GNGETPESSGKKGDHLIGDYYVAFDKHYKAEVKELTAQYQAEGLNEEEAKAKAEANSPLM
CCCCCCCCCCCCCCCEEECEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEE
LEAREMLRKWEANDPEIRALWKKMNDWVYAGFDETYKMMGVSFDKIYYESNTYLEGKEKV
HHHHHHHHHHCCCCHHHHHHHHHHCCCEEECHHHHHHHHCCCHHHEEECCCCEECCHHHH
MEGLEKGFFYRKEDNSVWADLTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFQDYPINKM
HHHHHHCCCEEECCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCEEEEEEECCCCEE
IYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSREGTVVDADDLME
EEEEECCCCCHHHHHHHHHHHHCHHHCCCEEEEECCCEECCCCCCCCCCCCEECHHHHHH
AMIETAKETSAELGKLDGLTQEEADNIARIVGLGALKYFILKVDARKNMTFNPKESIDFN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCC
GNTGPFIQYTYARIQSVLRKAAEAGIVIPEIIPAGLELSAKEEGLIQMLADFKSVVKQAG
CCCCCCCHHHHHHHHHHHHHHHHCCEECHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
SDYNPSIIANYAYDLVKEYNQFYHDFSILREENEALKVFRLALSANVGKIVKTAMGLLGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
EVPERM
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA