Click here to switch to the map view.

The map label for this gene is rnc

Identifier: 150003618

GI number: 150003618

Start: 1397592

End: 1398518

Strand: Reverse

Name: rnc

Synonym: BVU_1049

Alternate gene names: 150003618

Gene position: 1398518-1397592 (Counterclockwise)

Preceding gene: 150003619

Following gene: 150003610

Centisome position: 27.09

GC content: 41.75

Gene sequence:

>927_bases
GTGTTTAGCAATATAAAGGATAGGATAAGACTTCTTTTTCGTAAGGATAGGGAGTCTTATCTTCGTTTTTATAAGATGCT
TGGATTCTATCCCAAAGACATTAGCATCTACGAACAGGCTTTGCTTCACAAATCTTTATCAGTGAAGTCTGAAAAGGGGC
GTTTGCTTAATAATGAGCGTTTGGAATTCTTGGGGGATGCTATTCTGGATGCTGTGGTGGCAGATATTGTTTACAAAAGG
TTTGAAGGAAAGCGTGAGGGTTTTCTCACGAATACCCGCTCTAAAATAGTGCAGCGTGAAACATTGAATCGTTTGGCTAT
AGAGATTGGTTTGGATAAGCTGATCAAGTATACGGCCCGCCAGTCTTCTCATAACAGCTATATGTGCGGCAATGCATTCG
AAGCATTGGTAGGTGCTATTTATCTAGACAGGGGATATCGTGCCTGTAAATATTTCATGGAGCATCGTATTATTGGGCCT
TATATAAATTTGGAGAAGATTTCCCGTAAGGAGGTAAACTTTAAATCCAAGTTGATAGAATGGAGCCAGAAAAATCGTTT
TGAGGTTACCTTTGAGCTGATAACCCAATCACACGATCAGGGATATAATCCGACTTTCGAGAGTGAAGTTCTGGTGGAAG
GTATTTCGGGAGGAAAAGGAACCGGTTATTCTAAAAAAGAGTCTCAGCAAATGGCTGCGCGTGTGGCTTTGGGAAAAATA
AAGAATGATTCCGGCTTTATTGAATGTATTTTTGCGGCTAAGACTGCCCGTGAGTTGCCTCAGGAGGAGGTAACGGTTTC
TGATAGTAAGCCTTCAGACAGTGGGGCCGTTACTCCGGATCTTTCTTTGGAGGAGATTAAGAAAACGGATGTGGTCGAGC
AGATAATCAGTGAAGCGGAAGAAAAGGCTTTTAAGGAAAACGCTTAG

Upstream 100 bases:

>100_bases
ACGAAGCTCAGAAACGTACAGTAAACGCTGCATTGAGCAATACCTTCGGTTTTGGTGGACATAATGCATGTGTAATCGTA
AAAAAATATGCTGAATAATC

Downstream 100 bases:

>100_bases
CGGATTTTATCGATATTGTTTATAATTTATTAATTGGCTATTCCGGTGGTTTTGGGTATGTCCGGCAGGAATACATAATA
CATTGGAATATGCCCGATTA

Product: putative ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MFSNIKDRIRLLFRKDRESYLRFYKMLGFYPKDISIYEQALLHKSLSVKSEKGRLLNNERLEFLGDAILDAVVADIVYKR
FEGKREGFLTNTRSKIVQRETLNRLAIEIGLDKLIKYTARQSSHNSYMCGNAFEALVGAIYLDRGYRACKYFMEHRIIGP
YINLEKISRKEVNFKSKLIEWSQKNRFEVTFELITQSHDQGYNPTFESEVLVEGISGGKGTGYSKKESQQMAARVALGKI
KNDSGFIECIFAAKTARELPQEEVTVSDSKPSDSGAVTPDLSLEEIKKTDVVEQIISEAEEKAFKENA

Sequences:

>Translated_308_residues
MFSNIKDRIRLLFRKDRESYLRFYKMLGFYPKDISIYEQALLHKSLSVKSEKGRLLNNERLEFLGDAILDAVVADIVYKR
FEGKREGFLTNTRSKIVQRETLNRLAIEIGLDKLIKYTARQSSHNSYMCGNAFEALVGAIYLDRGYRACKYFMEHRIIGP
YINLEKISRKEVNFKSKLIEWSQKNRFEVTFELITQSHDQGYNPTFESEVLVEGISGGKGTGYSKKESQQMAARVALGKI
KNDSGFIECIFAAKTARELPQEEVTVSDSKPSDSGAVTPDLSLEEIKKTDVVEQIISEAEEKAFKENA
>Mature_308_residues
MFSNIKDRIRLLFRKDRESYLRFYKMLGFYPKDISIYEQALLHKSLSVKSEKGRLLNNERLEFLGDAILDAVVADIVYKR
FEGKREGFLTNTRSKIVQRETLNRLAIEIGLDKLIKYTARQSSHNSYMCGNAFEALVGAIYLDRGYRACKYFMEHRIIGP
YINLEKISRKEVNFKSKLIEWSQKNRFEVTFELITQSHDQGYNPTFESEVLVEGISGGKGTGYSKKESQQMAARVALGKI
KNDSGFIECIFAAKTARELPQEEVTVSDSKPSDSGAVTPDLSLEEIKKTDVVEQIISEAEEKAFKENA

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Escherichia coli, GI1788920, Length=228, Percent_Identity=30.2631578947368, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193202651, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17506883, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17137682, Length=124, Percent_Identity=30.6451612903226, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_BACV8 (A6KZ76)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298362.1
- ProteinModelPortal:   A6KZ76
- SMR:   A6KZ76
- STRING:   A6KZ76
- GeneID:   5302015
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1049
- NMPDR:   fig|435590.6.peg.989
- eggNOG:   COG0571
- HOGENOM:   HBG744556
- OMA:   KSLLIEW
- ProtClustDB:   CLSK823503
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 35250; Mature: 35250

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSNIKDRIRLLFRKDRESYLRFYKMLGFYPKDISIYEQALLHKSLSVKSEKGRLLNNER
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
LEFLGDAILDAVVADIVYKRFEGKREGFLTNTRSKIVQRETLNRLAIEIGLDKLIKYTAR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSSHNSYMCGNAFEALVGAIYLDRGYRACKYFMEHRIIGPYINLEKISRKEVNFKSKLIE
CCCCCCEECCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
WSQKNRFEVTFELITQSHDQGYNPTFESEVLVEGISGGKGTGYSKKESQQMAARVALGKI
HHCCCCEEEHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
KNDSGFIECIFAAKTARELPQEEVTVSDSKPSDSGAVTPDLSLEEIKKTDVVEQIISEAE
CCCCCCEEHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EKAFKENA
HHHHHCCC
>Mature Secondary Structure
MFSNIKDRIRLLFRKDRESYLRFYKMLGFYPKDISIYEQALLHKSLSVKSEKGRLLNNER
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
LEFLGDAILDAVVADIVYKRFEGKREGFLTNTRSKIVQRETLNRLAIEIGLDKLIKYTAR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSSHNSYMCGNAFEALVGAIYLDRGYRACKYFMEHRIIGPYINLEKISRKEVNFKSKLIE
CCCCCCEECCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
WSQKNRFEVTFELITQSHDQGYNPTFESEVLVEGISGGKGTGYSKKESQQMAARVALGKI
HHCCCCEEEHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
KNDSGFIECIFAAKTARELPQEEVTVSDSKPSDSGAVTPDLSLEEIKKTDVVEQIISEAE
CCCCCCEEHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EKAFKENA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA