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The map label for this gene is lolC [H]

Identifier: 150003446

GI number: 150003446

Start: 1175698

End: 1176936

Strand: Reverse

Name: lolC [H]

Synonym: BVU_0873

Alternate gene names: 150003446

Gene position: 1176936-1175698 (Counterclockwise)

Preceding gene: 150003447

Following gene: 150003436

Centisome position: 22.79

GC content: 46.57

Gene sequence:

>1239_bases
GTGAATTTTCCCTTTTATATAGCGAAGCGTTATCTTTTTTCCAAGAAGTCGCACAATGCCATTAATGTCATTTCAGCCAT
TTCCGTCTGCGGAGTGGCTTTGGCTACATTGGCATTGGTATGTACTTTGTCTGTTTTTAACGGCTTCCAGGATCTGGTGG
CTACTTTCTTTACGGCTTTTGATCCGGAGCTGAAAATTACGGCTGTCACCGGAAAGGTCTTTGACGGACAGGAAGCGCGT
ATAGAAGCTTTGCGCCGGATGCCGGAGATCGCTGTTTTTTCTGAGTCCTTGGAAGAGAATGCGATGGTTCAGTATAAGGG
CCGTCAGACTATGGCGGTGATCAAGGGAATTGAGGATAATTTCGAGGATCTGACCGCTATTGACAGTATTCTTTTCGGCC
GGGGGCAATTCGTGTTGCATGATGAAGTGGTGGATTATGCCATTCCCGGCATAGAATTGGTTTCCATCTTGGGAACGGGT
ATCAAATTCCTCGATCCGCTAGAGATTTATGCTCCCAAACGGGGAGCTAAAGTCAATATGGCCAATCCAGCTTCCAGCTT
TAACTCTGCCGATTTATATTCCAGCGGCCTTGTGTTTGCGGTGAACCAACAGAAGTATGACTCTTCTTACATTTTGACTT
CCCTCCAATTTGCCCGTAGGTTGTTCCAGTATGACACAGAAGTGAGTTCGGTAGAATTGAAATTGAAGCCGGATGCAGAT
GTAGGGAGTGTAAAATCGAAGATACAGAAAATATTGGGAGATGGTTTCCGGGTGCAGGACCGGTATGAGCAGCAAGCGGA
TACTTTCCGCATTATGGAGATAGAGAAGCTGATATCTTATATTTTCCTTACCTTTATCCTGATGATAGCTTGCTTTAATG
TAATAGGCTCCTTGTCCATGCTGATTATAGATAAGAAGGCAGATGTAGTGACATTGCGCAATTTGGGGGCCAGCGACAAG
CTGATCACGCGTATATTCCTGTTCGAGGGGCGTATGATTTCACTGATAGGTGCGGTGGTTGGTGTGATACTGGGGCTGAT
CCTTTGCTTTATCCAGCAGGAATTCGGATTGCTTTCGCTGGGAGGTGGTAATTCTGGCGGTAATTTTGTGGTGGATGCCT
ATCCCGTCAGTGTCCATGTATGGGATATTGTTATAGTCTTTGCCACTGTGCTGGTGGTGGGCTTTCTTTCCGTGTGGTAT
CCCGTGCGTTATCTCAGCCGCAGGTTGCTGGGCAGGTAA

Upstream 100 bases:

>100_bases
CCATCAGTTGCGCATCATTCCCGAGTTGAAATTCTTTGTGGATGATTCATTGGATTATGCCGAACGTATAGACGAATTGT
TGAAAAAGTAGAACCGGGCG

Downstream 100 bases:

>100_bases
TTTATTTATTATTGTTGATACGGCTGATGTTTGTCGGTTTGTACGGTACGGCTTGGCTGCTTTCTTTGTTTTTATTCTTT
TCGTCTTTTGGCCTTATGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MNFPFYIAKRYLFSKKSHNAINVISAISVCGVALATLALVCTLSVFNGFQDLVATFFTAFDPELKITAVTGKVFDGQEAR
IEALRRMPEIAVFSESLEENAMVQYKGRQTMAVIKGIEDNFEDLTAIDSILFGRGQFVLHDEVVDYAIPGIELVSILGTG
IKFLDPLEIYAPKRGAKVNMANPASSFNSADLYSSGLVFAVNQQKYDSSYILTSLQFARRLFQYDTEVSSVELKLKPDAD
VGSVKSKIQKILGDGFRVQDRYEQQADTFRIMEIEKLISYIFLTFILMIACFNVIGSLSMLIIDKKADVVTLRNLGASDK
LITRIFLFEGRMISLIGAVVGVILGLILCFIQQEFGLLSLGGGNSGGNFVVDAYPVSVHVWDIVIVFATVLVVGFLSVWY
PVRYLSRRLLGR

Sequences:

>Translated_412_residues
MNFPFYIAKRYLFSKKSHNAINVISAISVCGVALATLALVCTLSVFNGFQDLVATFFTAFDPELKITAVTGKVFDGQEAR
IEALRRMPEIAVFSESLEENAMVQYKGRQTMAVIKGIEDNFEDLTAIDSILFGRGQFVLHDEVVDYAIPGIELVSILGTG
IKFLDPLEIYAPKRGAKVNMANPASSFNSADLYSSGLVFAVNQQKYDSSYILTSLQFARRLFQYDTEVSSVELKLKPDAD
VGSVKSKIQKILGDGFRVQDRYEQQADTFRIMEIEKLISYIFLTFILMIACFNVIGSLSMLIIDKKADVVTLRNLGASDK
LITRIFLFEGRMISLIGAVVGVILGLILCFIQQEFGLLSLGGGNSGGNFVVDAYPVSVHVWDIVIVFATVLVVGFLSVWY
PVRYLSRRLLGR
>Mature_412_residues
MNFPFYIAKRYLFSKKSHNAINVISAISVCGVALATLALVCTLSVFNGFQDLVATFFTAFDPELKITAVTGKVFDGQEAR
IEALRRMPEIAVFSESLEENAMVQYKGRQTMAVIKGIEDNFEDLTAIDSILFGRGQFVLHDEVVDYAIPGIELVSILGTG
IKFLDPLEIYAPKRGAKVNMANPASSFNSADLYSSGLVFAVNQQKYDSSYILTSLQFARRLFQYDTEVSSVELKLKPDAD
VGSVKSKIQKILGDGFRVQDRYEQQADTFRIMEIEKLISYIFLTFILMIACFNVIGSLSMLIIDKKADVVTLRNLGASDK
LITRIFLFEGRMISLIGAVVGVILGLILCFIQQEFGLLSLGGGNSGGNFVVDAYPVSVHVWDIVIVFATVLVVGFLSVWY
PVRYLSRRLLGR

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=421, Percent_Identity=24.2280285035629, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1787360, Length=334, Percent_Identity=23.6526946107784, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45678; Mature: 45678

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPFYIAKRYLFSKKSHNAINVISAISVCGVALATLALVCTLSVFNGFQDLVATFFTAF
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPELKITAVTGKVFDGQEARIEALRRMPEIAVFSESLEENAMVQYKGRQTMAVIKGIEDN
CCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCC
FEDLTAIDSILFGRGQFVLHDEVVDYAIPGIELVSILGTGIKFLDPLEIYAPKRGAKVNM
HHHHHHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHCCCHHCCCHHHCCCCCCCEEEE
ANPASSFNSADLYSSGLVFAVNQQKYDSSYILTSLQFARRLFQYDTEVSSVELKLKPDAD
CCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
VGSVKSKIQKILGDGFRVQDRYEQQADTFRIMEIEKLISYIFLTFILMIACFNVIGSLSM
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LIIDKKADVVTLRNLGASDKLITRIFLFEGRMISLIGAVVGVILGLILCFIQQEFGLLSL
EEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
GGGNSGGNFVVDAYPVSVHVWDIVIVFATVLVVGFLSVWYPVRYLSRRLLGR
CCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFPFYIAKRYLFSKKSHNAINVISAISVCGVALATLALVCTLSVFNGFQDLVATFFTAF
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPELKITAVTGKVFDGQEARIEALRRMPEIAVFSESLEENAMVQYKGRQTMAVIKGIEDN
CCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCC
FEDLTAIDSILFGRGQFVLHDEVVDYAIPGIELVSILGTGIKFLDPLEIYAPKRGAKVNM
HHHHHHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHCCCHHCCCHHHCCCCCCCEEEE
ANPASSFNSADLYSSGLVFAVNQQKYDSSYILTSLQFARRLFQYDTEVSSVELKLKPDAD
CCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
VGSVKSKIQKILGDGFRVQDRYEQQADTFRIMEIEKLISYIFLTFILMIACFNVIGSLSM
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LIIDKKADVVTLRNLGASDKLITRIFLFEGRMISLIGAVVGVILGLILCFIQQEFGLLSL
EEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
GGGNSGGNFVVDAYPVSVHVWDIVIVFATVLVVGFLSVWYPVRYLSRRLLGR
CCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]