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The map label for this gene is ahpC [H]

Identifier: 150003422

GI number: 150003422

Start: 1150668

End: 1151234

Strand: Reverse

Name: ahpC [H]

Synonym: BVU_0847

Alternate gene names: 150003422

Gene position: 1151234-1150668 (Counterclockwise)

Preceding gene: 150003424

Following gene: 150003421

Centisome position: 22.3

GC content: 39.86

Gene sequence:

>567_bases
ATGGAACCAATTATTAATTCACAAGTTCCTGAATTTAAAGTTCAGGCATTCCATAATGGAGAGTTTAAAACCGTAACTAA
TAAAGATATTGAAGGTAAATGGGCTATTTTCTTCTTCTATCCTGCTGACTTTACGTTTGTATGCCCTACCGAACTTGTAG
ATATTGCTGAAAAGTATAATCAGTTCAAAGCAATGGGAGTGGAAGTATATTCTGTAAGCACCGATTCACATTTCGTTCAT
AAAGCATGGCATGATGCGTCTGAAAGTATCCGCAAAATCACTTATCCGATGTTGGCAGATCCTACAGGTGCTTTGTCGCG
TGCATTTGGTGTGATGATTGAAGAAGACGGTATGGCTTATCGTGGTACTTTTGTAGTGAATCCCGAAGGCAAGATCAAAT
TAGCTGAAATTCAGGACAACAGCATCGGGCGTAATGCTGATGAACTTCTTCGTAAGGTAGAAGCTGCCCAGTTTGTAGCC
ACTCATGATGGTGAGGTTTGTCCTGCTAAATGGAAGAAAGGTGCTGAGACCTTGAAACCGAGTATTGATTTGGTAGGTAA
AATTTAA

Upstream 100 bases:

>100_bases
CCTAATAATTAGGTATTGTGGAAGGTGCTGAAGTCGGCTACCTTTGCAAATGTAATAATTACAATTTAAAAATCAGTTTT
AATTTAAAAATAAAAAGAGT

Downstream 100 bases:

>100_bases
AGTATAGAACTCATGTTAGATAGTGCGATAAAAGATCAGTTAAAAGGTCTTTTTGCCCAATTGGAAGCGCACTATACTTT
TGACATCTTTGTCCACCCTC

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MEPIINSQVPEFKVQAFHNGEFKTVTNKDIEGKWAIFFFYPADFTFVCPTELVDIAEKYNQFKAMGVEVYSVSTDSHFVH
KAWHDASESIRKITYPMLADPTGALSRAFGVMIEEDGMAYRGTFVVNPEGKIKLAEIQDNSIGRNADELLRKVEAAQFVA
THDGEVCPAKWKKGAETLKPSIDLVGKI

Sequences:

>Translated_188_residues
MEPIINSQVPEFKVQAFHNGEFKTVTNKDIEGKWAIFFFYPADFTFVCPTELVDIAEKYNQFKAMGVEVYSVSTDSHFVH
KAWHDASESIRKITYPMLADPTGALSRAFGVMIEEDGMAYRGTFVVNPEGKIKLAEIQDNSIGRNADELLRKVEAAQFVA
THDGEVCPAKWKKGAETLKPSIDLVGKI
>Mature_188_residues
MEPIINSQVPEFKVQAFHNGEFKTVTNKDIEGKWAIFFFYPADFTFVCPTELVDIAEKYNQFKAMGVEVYSVSTDSHFVH
KAWHDASESIRKITYPMLADPTGALSRAFGVMIEEDGMAYRGTFVVNPEGKIKLAEIQDNSIGRNADELLRKVEAAQFVA
THDGEVCPAKWKKGAETLKPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=45.8100558659218, Blast_Score=169, Evalue=1e-42,
Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=44.5054945054945, Blast_Score=168, Evalue=2e-42,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=42.3076923076923, Blast_Score=164, Evalue=3e-41,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=38.4615384615385, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=38.4615384615385, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=38.4615384615385, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=39.572192513369, Blast_Score=151, Evalue=4e-37,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=45.679012345679, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI4758638, Length=153, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI1786822, Length=185, Percent_Identity=61.0810810810811, Blast_Score=254, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=41.340782122905, Blast_Score=167, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI32565831, Length=181, Percent_Identity=43.0939226519337, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=181, Percent_Identity=43.0939226519337, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25153706, Length=165, Percent_Identity=27.8787878787879, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=40.1098901098901, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=37.5690607734807, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319407, Length=159, Percent_Identity=27.0440251572327, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17738015, Length=184, Percent_Identity=39.1304347826087, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21357347, Length=186, Percent_Identity=39.247311827957, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=38.121546961326, Blast_Score=146, Evalue=7e-36,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=38.121546961326, Blast_Score=146, Evalue=7e-36,
Organism=Drosophila melanogaster, GI17157991, Length=179, Percent_Identity=37.9888268156425, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24641739, Length=179, Percent_Identity=37.9888268156425, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=33.5443037974684, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=31.0126582278481, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=31.0126582278481, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=7e-18,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21052; Mature: 21052

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIINSQVPEFKVQAFHNGEFKTVTNKDIEGKWAIFFFYPADFTFVCPTELVDIAEKYN
CCCCCCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEEECCCEEEECHHHHHHHHHHHH
QFKAMGVEVYSVSTDSHFVHKAWHDASESIRKITYPMLADPTGALSRAFGVMIEEDGMAY
HHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCEEECCCCCEE
RGTFVVNPEGKIKLAEIQDNSIGRNADELLRKVEAAQFVATHDGEVCPAKWKKGAETLKP
EEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHEEECCCCCCCCHHHHCCHHHHCC
SIDLVGKI
CCEEEECC
>Mature Secondary Structure
MEPIINSQVPEFKVQAFHNGEFKTVTNKDIEGKWAIFFFYPADFTFVCPTELVDIAEKYN
CCCCCCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEEECCCEEEECHHHHHHHHHHHH
QFKAMGVEVYSVSTDSHFVHKAWHDASESIRKITYPMLADPTGALSRAFGVMIEEDGMAY
HHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCEEECCCCCEE
RGTFVVNPEGKIKLAEIQDNSIGRNADELLRKVEAAQFVATHDGEVCPAKWKKGAETLKP
EEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHEEECCCCCCCCHHHHCCHHHHCC
SIDLVGKI
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]