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The map label for this gene is rprX [H]

Identifier: 150003410

GI number: 150003410

Start: 1126877

End: 1128262

Strand: Reverse

Name: rprX [H]

Synonym: BVU_0833

Alternate gene names: 150003410

Gene position: 1128262-1126877 (Counterclockwise)

Preceding gene: 150003412

Following gene: 150003409

Centisome position: 21.85

GC content: 39.25

Gene sequence:

>1386_bases
ATGACAATCAAACATATTCGTTGGGTAGCTTGTATCGGACTGTTGGCAATCATCTGTTTGCAGTACGTTTGGCTTGTAAA
TACCTATAAGCTAACTAAGGAAAGTATACAGTTCAGAAGCAATGAAGTATTTAGAGATGCAACGATGCGTGAGGTGTTTT
ATCGCATGGAAGTATATCAAGATTCTTTGCAAAAGAAGTATAAGGACAAAGATACTTCCATTATGGTTAGAATAAATCTG
GATGAAGATTATGATTTTTTTGAGGATGGCAGAGGTGATAAAAATGTGAACCAATGGTTGATGTCCAATATGCAGGTTTC
CATGCAAGAAATTGTCAAGAGGGATTATAAATTGTCTGTTTCTTTGTCAAGTTTAGATTCTATTTATCGGACAGGCCTTG
CTGCCGAAGGATTGGATGCAGAAGTAATAACTTGTGTGACAGATTCGCTGGGGAATATTCTTAGAAGTTCCCGTTCCATA
CAGGTAGGGGATTATGGCTTGTTGAAAACCGGATTACAACCTATCAATTATAAATGTACGGAGAATCTTCAGGCTTTTAT
TGTTAATCCTTATTGGGTTATTTTCCAGCAGATGACCTTGCTCCTCATTGCTACTGTCTTGATGATGGCAATGATCGTCT
ATTGTCTTGTTTATCAGATTCGTATTATTGCTCATCAGAATAAAATAGCTAGGATGCGTGAGGATTTCTCATACGCCATG
ATTCATGAGATGAAGACTCCTCTTGCCTGTATTTTGATGGGGACCCGAATGTTGAAATCAGGAAAGTTGGATATTTTTCC
GGATAAACGCGAGAAGCATTTTCAGATATTGGAGGACGAGAGTGAACATTTATTGTCACTGACTAACAAAGTGCTGACGC
TGTCAAAATTGGAAAATGCTCAATTGAGGCTTTGGAAAAAGGAGATACAACTCCGTCCGATGTTAGAGGATCTTATTGAG
AAATATACTGCTAAGGCAGATAAACCAGTACATTTCTCTCTTCATTTGGAATCGGAATGGGTATATGCTGATGAAGAATT
CTTGAAAGAAGCTATCGGTAATTTGGTAGATAATTCTATAAAATATTCAGGTGAAGAGGTGGACATACAGATTTCATCCT
TGCGTCAGGACTATAACTTTTATTTGATAAAGGTAAGAGATAACGGCATAGGTATTCCGTTGAAGGACCAGAGTCGTATT
TTCGAGAAGTACGAGCGTGCTTCGGCTGCCGACCGCAGCCGTAAAGGCGGTGCGTCAGGCTTCGGATTGGGTTTGAATTA
TGTTTTCCGCGTGGCTGAAGCGCATGGTGGAAAAGTGTGTGTAGAAAGCATTGAAGGGGAGTATAGTGAATTTTTTCTTT
TTTTGCCGAGTGGGGAGAAGAAATAA

Upstream 100 bases:

>100_bases
TCTTTAACTTTGACGAAACAAAAGTAGGGAGACTTTTTTCCTTACGTGGTTAATGGCAGGTTAACACAATGTTAACAAAG
TATGGATAGGATATAAGTGT

Downstream 100 bases:

>100_bases
ATATTTTTTAAGGAGGAAGATGATATGATAAAACTGTTGTTGGTGGAAGATGATGCCAATCTTTGTTATATTATTCGTGG
TGGATTGGAGGATATGATAG

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTIKHIRWVACIGLLAIICLQYVWLVNTYKLTKESIQFRSNEVFRDATMREVFYRMEVYQDSLQKKYKDKDTSIMVRINL
DEDYDFFEDGRGDKNVNQWLMSNMQVSMQEIVKRDYKLSVSLSSLDSIYRTGLAAEGLDAEVITCVTDSLGNILRSSRSI
QVGDYGLLKTGLQPINYKCTENLQAFIVNPYWVIFQQMTLLLIATVLMMAMIVYCLVYQIRIIAHQNKIARMREDFSYAM
IHEMKTPLACILMGTRMLKSGKLDIFPDKREKHFQILEDESEHLLSLTNKVLTLSKLENAQLRLWKKEIQLRPMLEDLIE
KYTAKADKPVHFSLHLESEWVYADEEFLKEAIGNLVDNSIKYSGEEVDIQISSLRQDYNFYLIKVRDNGIGIPLKDQSRI
FEKYERASAADRSRKGGASGFGLGLNYVFRVAEAHGGKVCVESIEGEYSEFFLFLPSGEKK

Sequences:

>Translated_461_residues
MTIKHIRWVACIGLLAIICLQYVWLVNTYKLTKESIQFRSNEVFRDATMREVFYRMEVYQDSLQKKYKDKDTSIMVRINL
DEDYDFFEDGRGDKNVNQWLMSNMQVSMQEIVKRDYKLSVSLSSLDSIYRTGLAAEGLDAEVITCVTDSLGNILRSSRSI
QVGDYGLLKTGLQPINYKCTENLQAFIVNPYWVIFQQMTLLLIATVLMMAMIVYCLVYQIRIIAHQNKIARMREDFSYAM
IHEMKTPLACILMGTRMLKSGKLDIFPDKREKHFQILEDESEHLLSLTNKVLTLSKLENAQLRLWKKEIQLRPMLEDLIE
KYTAKADKPVHFSLHLESEWVYADEEFLKEAIGNLVDNSIKYSGEEVDIQISSLRQDYNFYLIKVRDNGIGIPLKDQSRI
FEKYERASAADRSRKGGASGFGLGLNYVFRVAEAHGGKVCVESIEGEYSEFFLFLPSGEKK
>Mature_460_residues
TIKHIRWVACIGLLAIICLQYVWLVNTYKLTKESIQFRSNEVFRDATMREVFYRMEVYQDSLQKKYKDKDTSIMVRINLD
EDYDFFEDGRGDKNVNQWLMSNMQVSMQEIVKRDYKLSVSLSSLDSIYRTGLAAEGLDAEVITCVTDSLGNILRSSRSIQ
VGDYGLLKTGLQPINYKCTENLQAFIVNPYWVIFQQMTLLLIATVLMMAMIVYCLVYQIRIIAHQNKIARMREDFSYAMI
HEMKTPLACILMGTRMLKSGKLDIFPDKREKHFQILEDESEHLLSLTNKVLTLSKLENAQLRLWKKEIQLRPMLEDLIEK
YTAKADKPVHFSLHLESEWVYADEEFLKEAIGNLVDNSIKYSGEEVDIQISSLRQDYNFYLIKVRDNGIGIPLKDQSRIF
EKYERASAADRSRKGGASGFGLGLNYVFRVAEAHGGKVCVESIEGEYSEFFLFLPSGEKK

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=31.3304721030043, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=26.890756302521, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=27.1966527196653, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=213, Percent_Identity=28.169014084507, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=26.1061946902655, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=23.7668161434978, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=27.5229357798165, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=25.8771929824561, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=25.9414225941423, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=25.3218884120172, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=209, Percent_Identity=26.7942583732057, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=26.1261261261261, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=219, Percent_Identity=26.027397260274, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53354; Mature: 53223

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKHIRWVACIGLLAIICLQYVWLVNTYKLTKESIQFRSNEVFRDATMREVFYRMEVYQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DSLQKKYKDKDTSIMVRINLDEDYDFFEDGRGDKNVNQWLMSNMQVSMQEIVKRDYKLSV
HHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
SLSSLDSIYRTGLAAEGLDAEVITCVTDSLGNILRSSRSIQVGDYGLLKTGLQPINYKCT
EHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCCEEC
ENLQAFIVNPYWVIFQQMTLLLIATVLMMAMIVYCLVYQIRIIAHQNKIARMREDFSYAM
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHEMKTPLACILMGTRMLKSGKLDIFPDKREKHFQILEDESEHLLSLTNKVLTLSKLENA
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCH
QLRLWKKEIQLRPMLEDLIEKYTAKADKPVHFSLHLESEWVYADEEFLKEAIGNLVDNSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCHHHHHHHHHHHHCCCC
KYSGEEVDIQISSLRQDYNFYLIKVRDNGIGIPLKDQSRIFEKYERASAADRSRKGGASG
CCCCCEEEEEHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
FGLGLNYVFRVAEAHGGKVCVESIEGEYSEFFLFLPSGEKK
CCHHHHHHHHHHHCCCCEEEHHHHCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TIKHIRWVACIGLLAIICLQYVWLVNTYKLTKESIQFRSNEVFRDATMREVFYRMEVYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DSLQKKYKDKDTSIMVRINLDEDYDFFEDGRGDKNVNQWLMSNMQVSMQEIVKRDYKLSV
HHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
SLSSLDSIYRTGLAAEGLDAEVITCVTDSLGNILRSSRSIQVGDYGLLKTGLQPINYKCT
EHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCCEEC
ENLQAFIVNPYWVIFQQMTLLLIATVLMMAMIVYCLVYQIRIIAHQNKIARMREDFSYAM
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHEMKTPLACILMGTRMLKSGKLDIFPDKREKHFQILEDESEHLLSLTNKVLTLSKLENA
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCH
QLRLWKKEIQLRPMLEDLIEKYTAKADKPVHFSLHLESEWVYADEEFLKEAIGNLVDNSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCHHHHHHHHHHHHCCCC
KYSGEEVDIQISSLRQDYNFYLIKVRDNGIGIPLKDQSRIFEKYERASAADRSRKGGASG
CCCCCEEEEEHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
FGLGLNYVFRVAEAHGGKVCVESIEGEYSEFFLFLPSGEKK
CCHHHHHHHHHHHCCCCEEEHHHHCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]