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The map label for this gene is pepQ [H]

Identifier: 150003405

GI number: 150003405

Start: 1122178

End: 1123959

Strand: Direct

Name: pepQ [H]

Synonym: BVU_0828

Alternate gene names: 150003405

Gene position: 1122178-1123959 (Clockwise)

Preceding gene: 150003358

Following gene: 150003406

Centisome position: 21.73

GC content: 41.75

Gene sequence:

>1782_bases
ATGAAATCGGAAATTATAAATAGAATAGCTAGTCTGCGCAATTTCATGCGTAAACACAAGCTTTCAGCCTTTATTATTCC
CAGTACGGATCCCCATTCGGGAGAGTATATCCCCAAACATTGGGAAGCACGTAAATGGATATCAGGTTTCACAGGTTCGG
CAGGTACGGTTGTCGTAACACTGGATAAAGCCGGACTTTGGACAGATTCACGCTATTTTCTTCAAGCGGCCGAACAATTA
GAAAACACAGGTATTACTTTATTCAAGGAACGATTACCGGAAACTCCTTCCATTGTAGAGTGGTTGGGCTGTGTATTGAA
TGCAGAAGACAATGTGGGTATAGACGGTTGGGTGAACAGCTATCAAGAAACAAGCAACTTACAGAAAGAATTAGAAAAAA
AACAGATACACTTAACCCTTGCTCCCGATCCATTCAATGAATTATGGACAGATCGGCCTGCATTGCCCGATAACAAAGTG
TTTATACATGAATTGAAATATGCCGGTCTCAGTTGCAAGGATAAAATCACTCAAATACGAGAAGCAATCCGTCGTAACAG
TTGCACAGGCATTTTAATTTCCGCACTGGATGAAGTGGCATGGACCCTAAACTTACGGGGAAGTGACGTACACTGCAATC
CGGTATTTGTAAGTTACCTTCTCATCACGGAATATAGTTCTACCTTATATATAATAGAGAATAAACTGTCAGATGAAGTA
AAAGACTATCTAACAGAAAACGAAATTAAAGTAAGGCCTTATTCAACAATTGAAAAAGATTTAAAAGATTTTACCGGCAA
ACTCCTGTTGTCAGCTAATATCAATGCCGCTGTCCATGCAGCAGCCTGCGCCCATTCCTTAATAAAAATAGCTCCTTCGC
CTGTACTTTTTTTAAAAGCGATAAAGAATGAGACAGAAATAGAAGGCTTCCATCGCGCAATGAAACGCGACGGAGTAGCC
ATGGTTAAATTTCTCCGCTGGCTGAAAGCTGCTGTTTCTACTGGAAATGAAACCGAAATAAGTATAGATAAGAAATTATA
CGAATTCCGCGCCGGACAACCCCACTTCAATGGTATCAGTTTTGACACCATTGCCGGATATAAAGCTCATGGCGCTATTG
TTCACTATGAAGCAACCCCCGAAACCGATATTCCCTTAAAACCTGAAGGCATGCTGCTGCTGGACAGTGGAGCACAATAT
TTGGACGGAACAACTGATATTACTCGTACTATCGTTTTAGGAGCACTCACGAAAGAAGAAAAAACAGATTACACATTAGT
CTTAAAAGGATTTATCCAACTCTCAATGGCTCAATTTCCACATGGAACTTGCGGAACACAACTAGATGCGCTGGCTCGCC
TCCCTATGTGGAAAGCCGGAATCAATTACCTGCATGGAACAGGCCACGGTGTAGGTTGTTTTCTGAATGTACACGAAGGT
CCTCACCAATTCCGCATGAACCACATGCCGGCCTTACTTGTTCCAGGCATGACAGTAACCAACGAGCCCGGTATATATAA
AACCGGACGCCATGGAGTACGTACGGAAAATACCATGTTAATTGTTCCGTCACAAGAAACAGAATTCGGCACTTACTATA
AATTCGAGCCACTTACCCTCTGCCCTATTGACAAAGAAGCCATCCTGACAGATATGCTGAGCGATGAAGAAATAACATGG
TTCAACCAATATCATGAAAAAGTTTACAATTGTTTGAATCCGGAATTGAACAACGAGGAACGCGAGTGGTTAAAAGAAGT
AACATCTCCTTTAAAACGGTAG

Upstream 100 bases:

>100_bases
ATACTTTCTTTATTTACAAAACTTTCCGCAATTATTTATTTAAAATAATCTAGAAATCGTATCTTTGCTTTCTAGTACAA
ACCATTATAAACCTATTAAA

Downstream 100 bases:

>100_bases
AAATTAATTATGGCACTTATAAAATCAGTGAGAGGATTCACTCCAAAAATCGGCGAGAACTGTTATTTAGCCGATAATGC
CACTATTATTGGCGATGTTG

Product: putative aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MKSEIINRIASLRNFMRKHKLSAFIIPSTDPHSGEYIPKHWEARKWISGFTGSAGTVVVTLDKAGLWTDSRYFLQAAEQL
ENTGITLFKERLPETPSIVEWLGCVLNAEDNVGIDGWVNSYQETSNLQKELEKKQIHLTLAPDPFNELWTDRPALPDNKV
FIHELKYAGLSCKDKITQIREAIRRNSCTGILISALDEVAWTLNLRGSDVHCNPVFVSYLLITEYSSTLYIIENKLSDEV
KDYLTENEIKVRPYSTIEKDLKDFTGKLLLSANINAAVHAAACAHSLIKIAPSPVLFLKAIKNETEIEGFHRAMKRDGVA
MVKFLRWLKAAVSTGNETEISIDKKLYEFRAGQPHFNGISFDTIAGYKAHGAIVHYEATPETDIPLKPEGMLLLDSGAQY
LDGTTDITRTIVLGALTKEEKTDYTLVLKGFIQLSMAQFPHGTCGTQLDALARLPMWKAGINYLHGTGHGVGCFLNVHEG
PHQFRMNHMPALLVPGMTVTNEPGIYKTGRHGVRTENTMLIVPSQETEFGTYYKFEPLTLCPIDKEAILTDMLSDEEITW
FNQYHEKVYNCLNPELNNEEREWLKEVTSPLKR

Sequences:

>Translated_593_residues
MKSEIINRIASLRNFMRKHKLSAFIIPSTDPHSGEYIPKHWEARKWISGFTGSAGTVVVTLDKAGLWTDSRYFLQAAEQL
ENTGITLFKERLPETPSIVEWLGCVLNAEDNVGIDGWVNSYQETSNLQKELEKKQIHLTLAPDPFNELWTDRPALPDNKV
FIHELKYAGLSCKDKITQIREAIRRNSCTGILISALDEVAWTLNLRGSDVHCNPVFVSYLLITEYSSTLYIIENKLSDEV
KDYLTENEIKVRPYSTIEKDLKDFTGKLLLSANINAAVHAAACAHSLIKIAPSPVLFLKAIKNETEIEGFHRAMKRDGVA
MVKFLRWLKAAVSTGNETEISIDKKLYEFRAGQPHFNGISFDTIAGYKAHGAIVHYEATPETDIPLKPEGMLLLDSGAQY
LDGTTDITRTIVLGALTKEEKTDYTLVLKGFIQLSMAQFPHGTCGTQLDALARLPMWKAGINYLHGTGHGVGCFLNVHEG
PHQFRMNHMPALLVPGMTVTNEPGIYKTGRHGVRTENTMLIVPSQETEFGTYYKFEPLTLCPIDKEAILTDMLSDEEITW
FNQYHEKVYNCLNPELNNEEREWLKEVTSPLKR
>Mature_593_residues
MKSEIINRIASLRNFMRKHKLSAFIIPSTDPHSGEYIPKHWEARKWISGFTGSAGTVVVTLDKAGLWTDSRYFLQAAEQL
ENTGITLFKERLPETPSIVEWLGCVLNAEDNVGIDGWVNSYQETSNLQKELEKKQIHLTLAPDPFNELWTDRPALPDNKV
FIHELKYAGLSCKDKITQIREAIRRNSCTGILISALDEVAWTLNLRGSDVHCNPVFVSYLLITEYSSTLYIIENKLSDEV
KDYLTENEIKVRPYSTIEKDLKDFTGKLLLSANINAAVHAAACAHSLIKIAPSPVLFLKAIKNETEIEGFHRAMKRDGVA
MVKFLRWLKAAVSTGNETEISIDKKLYEFRAGQPHFNGISFDTIAGYKAHGAIVHYEATPETDIPLKPEGMLLLDSGAQY
LDGTTDITRTIVLGALTKEEKTDYTLVLKGFIQLSMAQFPHGTCGTQLDALARLPMWKAGINYLHGTGHGVGCFLNVHEG
PHQFRMNHMPALLVPGMTVTNEPGIYKTGRHGVRTENTMLIVPSQETEFGTYYKFEPLTLCPIDKEAILTDMLSDEEITW
FNQYHEKVYNCLNPELNNEEREWLKEVTSPLKR

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=614, Percent_Identity=39.5765472312704, Blast_Score=406, Evalue=1e-113,
Organism=Homo sapiens, GI264681565, Length=614, Percent_Identity=37.785016286645, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI93141226, Length=601, Percent_Identity=36.2728785357737, Blast_Score=369, Evalue=1e-102,
Organism=Escherichia coli, GI1788728, Length=233, Percent_Identity=30.4721030042918, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509539, Length=617, Percent_Identity=33.22528363047, Blast_Score=338, Evalue=7e-93,
Organism=Caenorhabditis elegans, GI25149105, Length=614, Percent_Identity=29.6416938110749, Blast_Score=272, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6322999, Length=652, Percent_Identity=35.8895705521472, Blast_Score=346, Evalue=5e-96,
Organism=Drosophila melanogaster, GI17137632, Length=619, Percent_Identity=36.9951534733441, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI161078230, Length=598, Percent_Identity=28.7625418060201, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21357287, Length=598, Percent_Identity=28.7625418060201, Blast_Score=269, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 66877; Mature: 66877

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSEIINRIASLRNFMRKHKLSAFIIPSTDPHSGEYIPKHWEARKWISGFTGSAGTVVVT
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEE
LDKAGLWTDSRYFLQAAEQLENTGITLFKERLPETPSIVEWLGCVLNAEDNVGIDGWVNS
EECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHH
YQETSNLQKELEKKQIHLTLAPDPFNELWTDRPALPDNKVFIHELKYAGLSCKDKITQIR
HHHHHHHHHHHHHCEEEEEECCCCHHHHHCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHH
EAIRRNSCTGILISALDEVAWTLNLRGSDVHCNPVFVSYLLITEYSSTLYIIENKLSDEV
HHHHHCCCCHHHHHHHHHHEEEEEECCCCEECCHHHHHHHHHHCCCCEEEEEECHHHHHH
KDYLTENEIKVRPYSTIEKDLKDFTGKLLLSANINAAVHAAACAHSLIKIAPSPVLFLKA
HHHHCCCCEEECCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHH
IKNETEIEGFHRAMKRDGVAMVKFLRWLKAAVSTGNETEISIDKKLYEFRAGQPHFNGIS
HCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCC
FDTIAGYKAHGAIVHYEATPETDIPLKPEGMLLLDSGAQYLDGTTDITRTIVLGALTKEE
CHHCCCEECCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
KTDYTLVLKGFIQLSMAQFPHGTCGTQLDALARLPMWKAGINYLHGTGHGVGCFLNVHEG
CCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHCCCEECCCCCCEEEEEEECCC
PHQFRMNHMPALLVPGMTVTNEPGIYKTGRHGVRTENTMLIVPSQETEFGTYYKFEPLTL
CHHHHHCCCCEEEECCEEECCCCCCEECCCCCCCCCCEEEEEECCCCCCCCEEEECCEEE
CPIDKEAILTDMLSDEEITWFNQYHEKVYNCLNPELNNEEREWLKEVTSPLKR
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSEIINRIASLRNFMRKHKLSAFIIPSTDPHSGEYIPKHWEARKWISGFTGSAGTVVVT
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEE
LDKAGLWTDSRYFLQAAEQLENTGITLFKERLPETPSIVEWLGCVLNAEDNVGIDGWVNS
EECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHH
YQETSNLQKELEKKQIHLTLAPDPFNELWTDRPALPDNKVFIHELKYAGLSCKDKITQIR
HHHHHHHHHHHHHCEEEEEECCCCHHHHHCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHH
EAIRRNSCTGILISALDEVAWTLNLRGSDVHCNPVFVSYLLITEYSSTLYIIENKLSDEV
HHHHHCCCCHHHHHHHHHHEEEEEECCCCEECCHHHHHHHHHHCCCCEEEEEECHHHHHH
KDYLTENEIKVRPYSTIEKDLKDFTGKLLLSANINAAVHAAACAHSLIKIAPSPVLFLKA
HHHHCCCCEEECCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHH
IKNETEIEGFHRAMKRDGVAMVKFLRWLKAAVSTGNETEISIDKKLYEFRAGQPHFNGIS
HCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCC
FDTIAGYKAHGAIVHYEATPETDIPLKPEGMLLLDSGAQYLDGTTDITRTIVLGALTKEE
CHHCCCEECCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
KTDYTLVLKGFIQLSMAQFPHGTCGTQLDALARLPMWKAGINYLHGTGHGVGCFLNVHEG
CCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHCCCEECCCCCCEEEEEEECCC
PHQFRMNHMPALLVPGMTVTNEPGIYKTGRHGVRTENTMLIVPSQETEFGTYYKFEPLTL
CHHHHHCCCCEEEECCEEECCCCCCEECCCCCCCCCCEEEEEECCCCCCCCEEEECCEEE
CPIDKEAILTDMLSDEEITWFNQYHEKVYNCLNPELNNEEREWLKEVTSPLKR
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]