Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 150003366

GI number: 150003366

Start: 1090264

End: 1091061

Strand: Reverse

Name: map [H]

Synonym: BVU_0784

Alternate gene names: 150003366

Gene position: 1091061-1090264 (Counterclockwise)

Preceding gene: 150003367

Following gene: 304360647

Centisome position: 21.13

GC content: 40.6

Gene sequence:

>798_bases
ATGATATTTCTTAAGACAGATGATGAGATAGAGCTGCTTCGTCAGAGTAACCTACTTGTAGGTAGGACTCTGGCTGAAGT
TGCTAAATTGATAAAACCCGGTGTGACAACTAAGGAACTTGACAAGGTGGCTGAAGAGTTTATTAGAGATAATGGAGCTG
TTCCTACTTTTAAAGGTTTTCCCAATCAGTATGGTGATCCGTTTCCCAGTACCTTGTGTACTTCGGTAAATGATCAGGTT
GTACACGGTATTCCCAATGATATCCCTTTGAAAGAAGGTGATATTGTTTCTGTTGATTGTGGTACTTATATGAATGGGTT
TTGTGGGGATTCAGCTTATACCTTCTGTGTAGGAGAAGTTGATCCTGAGGTCTTGAAACTTTTGAAGACAACAAAAGAAG
CTTTATATTTAGGTATAGAGAATGCCATTCATGGAAAGCGTTTGGGTGATATAGGTTTTGCTGTCCAGCAACATTGCGAG
GCTAATTCCTATGGTGTGGTAAGAGAATTCGTAGGTCATGGTATTGGAAAAGATATGCATGAAGATCCGCAGGTACCCAA
TTATGGAAAAAGAGGATACGGCACTCAGTTGAAAAAGGGTATGTGCATTGCCATCGAACCGATGATAACATTGGGTTCCC
GCCAGATAGTAATGGAAAGAGATGGATGGACAGTGCGTACACGCGATAGGAAATGTGCCGCTCACTTTGAGCATACAGTT
GCAATAGGAGTTGGGAAGGCAGATATTTTGTCCTCATTTGAATATGTCGAACAAGTATTAGGAGATAAAGCAATTTAA

Upstream 100 bases:

>100_bases
GTAGAAAGTCATTTGCTGATGCGCCATTACGACGGATTGTTAAATTCCGGAAGAATCAAGGGGCGTGCTGGTAATGTTGC
TGCATATTAATTAGTCTGAG

Downstream 100 bases:

>100_bases
TATGGCAAAGCAATCCGCAATAGAACAAGATGGAGTTATAGTTGAAGCATTGTCTAATGCAATGTTTCGTGTTGAGCTAG
AAAACGGGCATGAGATTACT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIFLKTDDEIELLRQSNLLVGRTLAEVAKLIKPGVTTKELDKVAEEFIRDNGAVPTFKGFPNQYGDPFPSTLCTSVNDQV
VHGIPNDIPLKEGDIVSVDCGTYMNGFCGDSAYTFCVGEVDPEVLKLLKTTKEALYLGIENAIHGKRLGDIGFAVQQHCE
ANSYGVVREFVGHGIGKDMHEDPQVPNYGKRGYGTQLKKGMCIAIEPMITLGSRQIVMERDGWTVRTRDRKCAAHFEHTV
AIGVGKADILSSFEYVEQVLGDKAI

Sequences:

>Translated_265_residues
MIFLKTDDEIELLRQSNLLVGRTLAEVAKLIKPGVTTKELDKVAEEFIRDNGAVPTFKGFPNQYGDPFPSTLCTSVNDQV
VHGIPNDIPLKEGDIVSVDCGTYMNGFCGDSAYTFCVGEVDPEVLKLLKTTKEALYLGIENAIHGKRLGDIGFAVQQHCE
ANSYGVVREFVGHGIGKDMHEDPQVPNYGKRGYGTQLKKGMCIAIEPMITLGSRQIVMERDGWTVRTRDRKCAAHFEHTV
AIGVGKADILSSFEYVEQVLGDKAI
>Mature_265_residues
MIFLKTDDEIELLRQSNLLVGRTLAEVAKLIKPGVTTKELDKVAEEFIRDNGAVPTFKGFPNQYGDPFPSTLCTSVNDQV
VHGIPNDIPLKEGDIVSVDCGTYMNGFCGDSAYTFCVGEVDPEVLKLLKTTKEALYLGIENAIHGKRLGDIGFAVQQHCE
ANSYGVVREFVGHGIGKDMHEDPQVPNYGKRGYGTQLKKGMCIAIEPMITLGSRQIVMERDGWTVRTRDRKCAAHFEHTV
AIGVGKADILSSFEYVEQVLGDKAI

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=250, Percent_Identity=41.2, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI40385867, Length=254, Percent_Identity=35.0393700787402, Blast_Score=148, Evalue=5e-36,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=38.9763779527559, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI1788728, Length=214, Percent_Identity=25.7009345794392, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=252, Percent_Identity=38.0952380952381, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323273, Length=246, Percent_Identity=35.7723577235772, Blast_Score=162, Evalue=6e-41,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=36.734693877551, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24583427, Length=248, Percent_Identity=35.0806451612903, Blast_Score=154, Evalue=4e-38,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29141; Mature: 29141

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLKTDDEIELLRQSNLLVGRTLAEVAKLIKPGVTTKELDKVAEEFIRDNGAVPTFKGF
CEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
PNQYGDPFPSTLCTSVNDQVVHGIPNDIPLKEGDIVSVDCGTYMNGFCGDSAYTFCVGEV
CCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCEEEEECCCHHCCCCCCCCEEEEECCC
DPEVLKLLKTTKEALYLGIENAIHGKRLGDIGFAVQQHCEANSYGVVREFVGHGIGKDMH
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC
EDPQVPNYGKRGYGTQLKKGMCIAIEPMITLGSRQIVMERDGWTVRTRDRKCAAHFEHTV
CCCCCCCCCCCCCCCHHHCCCEEEECHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHEE
AIGVGKADILSSFEYVEQVLGDKAI
EEECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIFLKTDDEIELLRQSNLLVGRTLAEVAKLIKPGVTTKELDKVAEEFIRDNGAVPTFKGF
CEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
PNQYGDPFPSTLCTSVNDQVVHGIPNDIPLKEGDIVSVDCGTYMNGFCGDSAYTFCVGEV
CCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCEEEEECCCHHCCCCCCCCEEEEECCC
DPEVLKLLKTTKEALYLGIENAIHGKRLGDIGFAVQQHCEANSYGVVREFVGHGIGKDMH
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC
EDPQVPNYGKRGYGTQLKKGMCIAIEPMITLGSRQIVMERDGWTVRTRDRKCAAHFEHTV
CCCCCCCCCCCCCCCHHHCCCEEEECHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHEE
AIGVGKADILSSFEYVEQVLGDKAI
EEECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]