Click here to switch to the map view.

The map label for this gene is lolA [H]

Identifier: 148828419

GI number: 148828419

Start: 1875752

End: 1876309

Strand: Direct

Name: lolA [H]

Synonym: CGSHiGG_10160

Alternate gene names: 148828419

Gene position: 1875752-1876309 (Clockwise)

Preceding gene: 148828418

Following gene: 148828420

Centisome position: 99.39

GC content: 37.46

Gene sequence:

>558_bases
TTGGCTGATGCGGCAAGTGAATTACAAATGCGTTTAGCTAAAGTCGATGTATTAAGTGCAGAATTTGTGCAAACAGTGAC
TTCTGGAAGTGGCAAAAATGTTCAACAAGGAAGTGGCAAACTTCAAATCAAACGCCCAAATTTATTCCGTATGGAGACTA
AAACCCCTCAAGAAACCCAGATTATTTCTGATGGTAAAACCTTATGGTTCTACGATCCATTTGTGCAACAAGTGACCGCA
CAATGGGTAAAAGATGCGGTAAATAATACTCCTTTTGTTTTGCTTACCAGCAATGATCATAGCCATTGGCATCAATATAC
GGTGACACAACAAGCGGATACCTTTGTGTTAAAACCAACCTTATCCACAAGCAACATTAAGCAATTTGATATTCGCGTTG
ATGTTAATGGAATATTGCGAAATTTCAGCACGACAGAGAAAGATGGTCAAACCAATCTTTATGTTTTACGTAATATTACT
AATCAAACCTTGTCTGATAGCTTGTTCCAATTCAAGCCAGAAAAAGGCATTGAAGTTGATGATCAACGCAAAAAATAA

Upstream 100 bases:

>100_bases
ATCGCATCGTCCAGAATACTAATTTAAAAGGAAAGTAAAATAGAAAAAAACAACCTTAAAATTTGCCGCACTTACCTTAC
TTGGTTTGAGTAATTTGGCA

Downstream 100 bases:

>100_bases
TGAATGATTATTTGAAATAAGGGCGTAGAAATACGCCCTTCAATTTTGTGAGAAATAAAAATGTCTAACCTCAATTTTGA
TTTTGCCGAAAATGATTTTC

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MADAASELQMRLAKVDVLSAEFVQTVTSGSGKNVQQGSGKLQIKRPNLFRMETKTPQETQIISDGKTLWFYDPFVQQVTA
QWVKDAVNNTPFVLLTSNDHSHWHQYTVTQQADTFVLKPTLSTSNIKQFDIRVDVNGILRNFSTTEKDGQTNLYVLRNIT
NQTLSDSLFQFKPEKGIEVDDQRKK

Sequences:

>Translated_185_residues
MADAASELQMRLAKVDVLSAEFVQTVTSGSGKNVQQGSGKLQIKRPNLFRMETKTPQETQIISDGKTLWFYDPFVQQVTA
QWVKDAVNNTPFVLLTSNDHSHWHQYTVTQQADTFVLKPTLSTSNIKQFDIRVDVNGILRNFSTTEKDGQTNLYVLRNIT
NQTLSDSLFQFKPEKGIEVDDQRKK
>Mature_184_residues
ADAASELQMRLAKVDVLSAEFVQTVTSGSGKNVQQGSGKLQIKRPNLFRMETKTPQETQIISDGKTLWFYDPFVQQVTAQ
WVKDAVNNTPFVLLTSNDHSHWHQYTVTQQADTFVLKPTLSTSNIKQFDIRVDVNGILRNFSTTEKDGQTNLYVLRNITN
QTLSDSLFQFKPEKGIEVDDQRKK

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=183, Percent_Identity=50.2732240437158, Blast_Score=191, Evalue=2e-50,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 21042; Mature: 20911

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAASELQMRLAKVDVLSAEFVQTVTSGSGKNVQQGSGKLQIKRPNLFRMETKTPQETQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCHHE
IISDGKTLWFYDPFVQQVTAQWVKDAVNNTPFVLLTSNDHSHWHQYTVTQQADTFVLKPT
EECCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCEEEEECC
LSTSNIKQFDIRVDVNGILRNFSTTEKDGQTNLYVLRNITNQTLSDSLFQFKPEKGIEVD
CCCCCCEEEEEEEEHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCC
DQRKK
CCCCC
>Mature Secondary Structure 
ADAASELQMRLAKVDVLSAEFVQTVTSGSGKNVQQGSGKLQIKRPNLFRMETKTPQETQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCHHE
IISDGKTLWFYDPFVQQVTAQWVKDAVNNTPFVLLTSNDHSHWHQYTVTQQADTFVLKPT
EECCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCEEEEECC
LSTSNIKQFDIRVDVNGILRNFSTTEKDGQTNLYVLRNITNQTLSDSLFQFKPEKGIEVD
CCCCCCEEEEEEEEHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCC
DQRKK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA