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The map label for this gene is lolA [H]

Identifier: 148828420

GI number: 148828420

Start: 1876370

End: 1877710

Strand: Direct

Name: lolA [H]

Synonym: CGSHiGG_10165

Alternate gene names: 148828420

Gene position: 1876370-1877710 (Clockwise)

Preceding gene: 148828419

Following gene: 148828424

Centisome position: 99.43

GC content: 41.91

Gene sequence:

>1341_bases
ATGTCTAACCTCAATTTTGATTTTGCCGAAAATGATTTTCGCCCACTGGCAGCCAAGATGCGTCCAACGAGTCTAGAACA
ATATTTTGGGCAAAGCCATTTAATTGGCGAGGGCAAGCCACTGCGAAAAGCTATCCAAGCTGGCCATATTCATTCTATGA
TTTTCTGGGGGCCTCCAGGTACGGGAAAAACAACGCTCGCAGAGATTATTGCACAATGTATTAATGCAGAAGTAGAGCGA
ATTTTTGCGGTGACGAGTGGTATCAAAGAAATTCGTGAAGCGATTGATCGTGCAAAACAAAATCGTCTTGCGGATCGTAA
AACTATCTTATTTGTGGATGAAGTCCATCGTTTTAATAAAAGCCAGCAAGATGCATTTTTACCGCACATTGAAGACGGAA
CCGTTATTTTTATTGGGGCGACAACAGAAAATCCCTCTTTTGAGCTAAATAATGCGTTGCTTTCTCGTGCCCGAGTGTAT
GTGCTGAAATCACTCACAACGGCTGAAATTGAACAAATTTTGCAGCAAGCTATAGAAGATCCTAAACGTGGATTGGGTAA
AGAGCGGTTAATTTTAGAAGAGAATTTACTGCAAGTACTTGCCGAATATGTTAATGGGGATGCACGATTAGCCTTGAATT
GCCTCGAATTAATGGTGGATATGGCAGATGAAACGGACAATGGAAAGAAAATTGACCGCACTTTATTAAAAGAAGTCTTA
GGTGAACGTCAAGCGAGATTTGATAAACAAGGTGATCGTTTCTATGATTTAATTTCTGCGCTACATAAATCTGTTCGAGG
TTCTGCTCCAGATGCTGCGCTGTATTGGTATGCACGAATTTTAACAGCGGGTGGAGACCCTTTATATGTCGCGCGCCGAT
TACTTGCTATTGCTTCAGAAGATGTGGGAAATGCGGATCCTCGTGCTATGCAAGTTGCATTGGCTGCTTGGGATTGCTTT
ACTCGAGAGGGGGCTTATGAAGGGGAGCGAGCCATCGCCCAAGCCATTATTTATCTTGCAGTAGCCCCAAAAAGTAATGC
GGTTTATACCGCATTTAACACTGCGAAACAGCAAGCGAAAGATTTACCTGATTACGATGTTCCACCACATTTACGCAATG
CGCCGACTAATTTAATGAAAGAGCTCGGATATGGCACTGAATATCGTTATGCTCACGATGAACCTAACGCTTATGCGGCA
GGCGAAAATTATTTCCCACCTGAATTACAAGACACTCAATATTATTTTCCGACAAATAGAGGTATGGAAATTCAGATTAA
GGAAAAACTAGAACGGTTACGTGAGCAAGATAAAAGTGCGGTGAAAAAACGGTATAAATAA

Upstream 100 bases:

>100_bases
AGAAAAAGGCATTGAAGTTGATGATCAACGCAAAAAATAATGAATGATTATTTGAAATAAGGGCGTAGAAATACGCCCTT
CAATTTTGTGAGAAATAAAA

Downstream 100 bases:

>100_bases
TCTTTATTTAGGATTTTTTTAGAATGGAATGAAAGTGCGGTTAATTTGAAAACTGTTTTGAAATTGACCGCACTTTTTTA
CTTAATTTTTTAAGCAAATC

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSNLNFDFAENDFRPLAAKMRPTSLEQYFGQSHLIGEGKPLRKAIQAGHIHSMIFWGPPGTGKTTLAEIIAQCINAEVER
IFAVTSGIKEIREAIDRAKQNRLADRKTILFVDEVHRFNKSQQDAFLPHIEDGTVIFIGATTENPSFELNNALLSRARVY
VLKSLTTAEIEQILQQAIEDPKRGLGKERLILEENLLQVLAEYVNGDARLALNCLELMVDMADETDNGKKIDRTLLKEVL
GERQARFDKQGDRFYDLISALHKSVRGSAPDAALYWYARILTAGGDPLYVARRLLAIASEDVGNADPRAMQVALAAWDCF
TREGAYEGERAIAQAIIYLAVAPKSNAVYTAFNTAKQQAKDLPDYDVPPHLRNAPTNLMKELGYGTEYRYAHDEPNAYAA
GENYFPPELQDTQYYFPTNRGMEIQIKEKLERLREQDKSAVKKRYK

Sequences:

>Translated_446_residues
MSNLNFDFAENDFRPLAAKMRPTSLEQYFGQSHLIGEGKPLRKAIQAGHIHSMIFWGPPGTGKTTLAEIIAQCINAEVER
IFAVTSGIKEIREAIDRAKQNRLADRKTILFVDEVHRFNKSQQDAFLPHIEDGTVIFIGATTENPSFELNNALLSRARVY
VLKSLTTAEIEQILQQAIEDPKRGLGKERLILEENLLQVLAEYVNGDARLALNCLELMVDMADETDNGKKIDRTLLKEVL
GERQARFDKQGDRFYDLISALHKSVRGSAPDAALYWYARILTAGGDPLYVARRLLAIASEDVGNADPRAMQVALAAWDCF
TREGAYEGERAIAQAIIYLAVAPKSNAVYTAFNTAKQQAKDLPDYDVPPHLRNAPTNLMKELGYGTEYRYAHDEPNAYAA
GENYFPPELQDTQYYFPTNRGMEIQIKEKLERLREQDKSAVKKRYK
>Mature_445_residues
SNLNFDFAENDFRPLAAKMRPTSLEQYFGQSHLIGEGKPLRKAIQAGHIHSMIFWGPPGTGKTTLAEIIAQCINAEVERI
FAVTSGIKEIREAIDRAKQNRLADRKTILFVDEVHRFNKSQQDAFLPHIEDGTVIFIGATTENPSFELNNALLSRARVYV
LKSLTTAEIEQILQQAIEDPKRGLGKERLILEENLLQVLAEYVNGDARLALNCLELMVDMADETDNGKKIDRTLLKEVLG
ERQARFDKQGDRFYDLISALHKSVRGSAPDAALYWYARILTAGGDPLYVARRLLAIASEDVGNADPRAMQVALAAWDCFT
REGAYEGERAIAQAIIYLAVAPKSNAVYTAFNTAKQQAKDLPDYDVPPHLRNAPTNLMKELGYGTEYRYAHDEPNAYAAG
ENYFPPELQDTQYYFPTNRGMEIQIKEKLERLREQDKSAVKKRYK

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=442, Percent_Identity=42.9864253393665, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI18426904, Length=442, Percent_Identity=38.9140271493213, Blast_Score=262, Evalue=5e-70,
Organism=Escherichia coli, GI1787119, Length=447, Percent_Identity=73.6017897091723, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1786676, Length=281, Percent_Identity=25.9786476868327, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324111, Length=430, Percent_Identity=39.5348837209302, Blast_Score=290, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6324039, Length=210, Percent_Identity=29.0476190476191, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 50306; Mature: 50174

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLNFDFAENDFRPLAAKMRPTSLEQYFGQSHLIGEGKPLRKAIQAGHIHSMIFWGPPG
CCCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCC
TGKTTLAEIIAQCINAEVERIFAVTSGIKEIREAIDRAKQNRLADRKTILFVDEVHRFNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHCCC
SQQDAFLPHIEDGTVIFIGATTENPSFELNNALLSRARVYVLKSLTTAEIEQILQQAIED
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKRGLGKERLILEENLLQVLAEYVNGDARLALNCLELMVDMADETDNGKKIDRTLLKEVL
HHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GERQARFDKQGDRFYDLISALHKSVRGSAPDAALYWYARILTAGGDPLYVARRLLAIASE
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
DVGNADPRAMQVALAAWDCFTREGAYEGERAIAQAIIYLAVAPKSNAVYTAFNTAKQQAK
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHH
DLPDYDVPPHLRNAPTNLMKELGYGTEYRYAHDEPNAYAAGENYFPPELQDTQYYFPTNR
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEECCCCC
GMEIQIKEKLERLREQDKSAVKKRYK
CCEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNLNFDFAENDFRPLAAKMRPTSLEQYFGQSHLIGEGKPLRKAIQAGHIHSMIFWGPPG
CCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCC
TGKTTLAEIIAQCINAEVERIFAVTSGIKEIREAIDRAKQNRLADRKTILFVDEVHRFNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHCCC
SQQDAFLPHIEDGTVIFIGATTENPSFELNNALLSRARVYVLKSLTTAEIEQILQQAIED
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKRGLGKERLILEENLLQVLAEYVNGDARLALNCLELMVDMADETDNGKKIDRTLLKEVL
HHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GERQARFDKQGDRFYDLISALHKSVRGSAPDAALYWYARILTAGGDPLYVARRLLAIASE
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
DVGNADPRAMQVALAAWDCFTREGAYEGERAIAQAIIYLAVAPKSNAVYTAFNTAKQQAK
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHH
DLPDYDVPPHLRNAPTNLMKELGYGTEYRYAHDEPNAYAAGENYFPPELQDTQYYFPTNR
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEECCCCC
GMEIQIKEKLERLREQDKSAVKKRYK
CCEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]