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The map label for this gene is sapD [H]

Identifier: 148828371

GI number: 148828371

Start: 1821976

End: 1823025

Strand: Reverse

Name: sapD [H]

Synonym: CGSHiGG_09870

Alternate gene names: 148828371

Gene position: 1823025-1821976 (Counterclockwise)

Preceding gene: 148828372

Following gene: 148828370

Centisome position: 96.6

GC content: 36.38

Gene sequence:

>1050_bases
ATGGCACTTTTAGACATTTGTAACCTCAATATTGAAATTCAAACCTCCAATGGACGTATAAAAATTGTAGATGGCGTCAA
TCTTTCCCTTAACGAAGGGGAAATCAGTGGATTAGTTGGCGAATCAGGCTCAGGAAAAAGCTTAATCGCTAAAGTCATTT
GTAATGCAATCAAAGAAAATTGGATTATTACTGCCGATCGCTTTCGTTTTCACGATGTCGAACTACTTAAACTCAGTCCT
AATAAACGACGTAAGATTGTCGGCAAAGAAATTTCAATGATTTTCCAAAATCCCTTATCTTGCCTTGATCCAAGTCGAAA
AATAGGGAAACAACTCATCCAAAATATTCCTAATTGGACATTTAAAAATAAATGGTGGAAATGGTTTGGGTGGAAAAAAA
GACGTGCTATTGAATTGTTACATCGCGTAGGAATTAAAGATCATCGTGATATTATGGCAAGCTATCCTAACGAACTGACA
GAAGGCGAAGGACAAAAAGTTATGATCGCAATGGCTGTCGCTAATCAGCCACGTTTATTAATCGCGGATGAACCAACAAA
TGCATTAGAATCAACCACAGCCCTACAAGTTTTTCGTTTACTTTCTAGTATGAACCAAAATCAGGGAACAACAATTTTAC
TTACGAGTAACGATATTAAAAGTATTAGTGAATGGTGCGATCAAATTTCAGTGCTTTATTGTGGGCAAAATACCGAATCT
GCCCCGACTGAAATATTAATCGAAAGTCCCCATCATCCTTATACCCAAGCCTTAATTAATGCAGTACCCGATTTTACTCA
ACCTTTGGGATTTAAAACTAAATTGGGTACGTTAGAAGGCACCGTGCCTATTTTAGAGCAAATGCCAATTGGCTGTCGTC
TTGGCCCAAGATGCCCTTTTGCACAAAAAAAATGTATGGAAAAACCAAGACGATTGAAAATAAAACAACACGAATTTTCT
TGTCATTATCCTATTAATTTACGAGAAAAAAATTTCAAAGAAAAAACAACCGCCACCCCTTTTATACTTAATTGCAAAGG
AAATGAATAA

Upstream 100 bases:

>100_bases
GTATTACTCCCTGGCTTTGCAATTATTTTTACTATTTTTATTAAGCATTATTTTTAGCAATGGCTTAACTAAAACCATCA
ATCAACATCAAGAATAGCCT

Downstream 100 bases:

>100_bases
TGCCCTTATTACAAGTGGAAGATTTAACTAAAACTTTTAAAGGTCACGCCAGTTTATTTGGTCGAAATCAATTCAATGCA
GTGGATAAAGTGAGTTTTAC

Product: peptide ABC transporter ATP-binding protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MALLDICNLNIEIQTSNGRIKIVDGVNLSLNEGEISGLVGESGSGKSLIAKVICNAIKENWIITADRFRFHDVELLKLSP
NKRRKIVGKEISMIFQNPLSCLDPSRKIGKQLIQNIPNWTFKNKWWKWFGWKKRRAIELLHRVGIKDHRDIMASYPNELT
EGEGQKVMIAMAVANQPRLLIADEPTNALESTTALQVFRLLSSMNQNQGTTILLTSNDIKSISEWCDQISVLYCGQNTES
APTEILIESPHHPYTQALINAVPDFTQPLGFKTKLGTLEGTVPILEQMPIGCRLGPRCPFAQKKCMEKPRRLKIKQHEFS
CHYPINLREKNFKEKTTATPFILNCKGNE

Sequences:

>Translated_349_residues
MALLDICNLNIEIQTSNGRIKIVDGVNLSLNEGEISGLVGESGSGKSLIAKVICNAIKENWIITADRFRFHDVELLKLSP
NKRRKIVGKEISMIFQNPLSCLDPSRKIGKQLIQNIPNWTFKNKWWKWFGWKKRRAIELLHRVGIKDHRDIMASYPNELT
EGEGQKVMIAMAVANQPRLLIADEPTNALESTTALQVFRLLSSMNQNQGTTILLTSNDIKSISEWCDQISVLYCGQNTES
APTEILIESPHHPYTQALINAVPDFTQPLGFKTKLGTLEGTVPILEQMPIGCRLGPRCPFAQKKCMEKPRRLKIKQHEFS
CHYPINLREKNFKEKTTATPFILNCKGNE
>Mature_348_residues
ALLDICNLNIEIQTSNGRIKIVDGVNLSLNEGEISGLVGESGSGKSLIAKVICNAIKENWIITADRFRFHDVELLKLSPN
KRRKIVGKEISMIFQNPLSCLDPSRKIGKQLIQNIPNWTFKNKWWKWFGWKKRRAIELLHRVGIKDHRDIMASYPNELTE
GEGQKVMIAMAVANQPRLLIADEPTNALESTTALQVFRLLSSMNQNQGTTILLTSNDIKSISEWCDQISVLYCGQNTESA
PTEILIESPHHPYTQALINAVPDFTQPLGFKTKLGTLEGTVPILEQMPIGCRLGPRCPFAQKKCMEKPRRLKIKQHEFSC
HYPINLREKNFKEKTTATPFILNCKGNE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=62.4242424242424, Blast_Score=459, Evalue=1e-131,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=37.1951219512195, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787759, Length=308, Percent_Identity=36.3636363636364, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI48994883, Length=308, Percent_Identity=34.0909090909091, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787500, Length=330, Percent_Identity=32.1212121212121, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI145693107, Length=269, Percent_Identity=30.8550185873606, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788506, Length=266, Percent_Identity=33.4586466165414, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1789962, Length=280, Percent_Identity=29.6428571428571, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787758, Length=306, Percent_Identity=28.7581699346405, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789890, Length=254, Percent_Identity=29.5275590551181, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786398, Length=256, Percent_Identity=30.078125, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787547, Length=266, Percent_Identity=26.6917293233083, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081834, Length=236, Percent_Identity=29.6610169491525, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994997, Length=237, Percent_Identity=26.1603375527426, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789891, Length=245, Percent_Identity=28.1632653061224, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790544, Length=232, Percent_Identity=28.0172413793103, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789032, Length=251, Percent_Identity=25.4980079681275, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787105, Length=220, Percent_Identity=26.3636363636364, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787029, Length=248, Percent_Identity=25.4032258064516, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788450, Length=239, Percent_Identity=25.9414225941423, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789672, Length=265, Percent_Identity=26.0377358490566, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788225, Length=264, Percent_Identity=25, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786345, Length=226, Percent_Identity=25.2212389380531, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790190, Length=229, Percent_Identity=29.6943231441048, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081791, Length=263, Percent_Identity=25.4752851711027, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790525, Length=231, Percent_Identity=27.7056277056277, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788644, Length=263, Percent_Identity=26.615969581749, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789991, Length=230, Percent_Identity=27.8260869565217, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=236, Percent_Identity=23.3050847457627, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786563, Length=217, Percent_Identity=27.1889400921659, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 39506; Mature: 39375

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLDICNLNIEIQTSNGRIKIVDGVNLSLNEGEISGLVGESGSGKSLIAKVICNAIKEN
CCEEEEECCEEEEEECCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCC
WIITADRFRFHDVELLKLSPNKRRKIVGKEISMIFQNPLSCLDPSRKIGKQLIQNIPNWT
EEEEECCEEECCEEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCC
FKNKWWKWFGWKKRRAIELLHRVGIKDHRDIMASYPNELTEGEGQKVMIAMAVANQPRLL
CCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCEEEEEEEECCCCEEE
IADEPTNALESTTALQVFRLLSSMNQNQGTTILLTSNDIKSISEWCDQISVLYCGQNTES
EECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCEEEEEECCCCCC
APTEILIESPHHPYTQALINAVPDFTQPLGFKTKLGTLEGTVPILEQMPIGCRLGPRCPF
CCCEEEEECCCCHHHHHHHHHCCCHHCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCH
AQKKCMEKPRRLKIKQHEFSCHYPINLREKNFKEKTTATPFILNCKGNE
HHHHHHCCCHHCEEEECCCEEECCCCCCCCCCCHHCCCCCEEEEECCCC
>Mature Secondary Structure 
ALLDICNLNIEIQTSNGRIKIVDGVNLSLNEGEISGLVGESGSGKSLIAKVICNAIKEN
CEEEEECCEEEEEECCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCC
WIITADRFRFHDVELLKLSPNKRRKIVGKEISMIFQNPLSCLDPSRKIGKQLIQNIPNWT
EEEEECCEEECCEEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCC
FKNKWWKWFGWKKRRAIELLHRVGIKDHRDIMASYPNELTEGEGQKVMIAMAVANQPRLL
CCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCEEEEEEEECCCCEEE
IADEPTNALESTTALQVFRLLSSMNQNQGTTILLTSNDIKSISEWCDQISVLYCGQNTES
EECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCEEEEEECCCCCC
APTEILIESPHHPYTQALINAVPDFTQPLGFKTKLGTLEGTVPILEQMPIGCRLGPRCPF
CCCEEEEECCCCHHHHHHHHHCCCHHCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCH
AQKKCMEKPRRLKIKQHEFSCHYPINLREKNFKEKTTATPFILNCKGNE
HHHHHHCCCHHCEEEECCCEEECCCCCCCCCCCHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]