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The map label for this gene is sapC [H]

Identifier: 148828372

GI number: 148828372

Start: 1823069

End: 1823917

Strand: Reverse

Name: sapC [H]

Synonym: CGSHiGG_09875

Alternate gene names: 148828372

Gene position: 1823917-1823069 (Counterclockwise)

Preceding gene: 148828373

Following gene: 148828371

Centisome position: 96.65

GC content: 35.34

Gene sequence:

>849_bases
ATGCAAAATAAAGAACCTGATGAATTTCGCGAAAGCACCTCAATCTTTCAAATTTGGTTACGCTTTCGTCAAAATACCAT
CGCACTTTTTAGCTTTTATTTATTAATCGCATTAATTTTTACCGCACTTTTTGCTAGTTATCTTGCACCTTATGCTGATA
ATCGACAATTTATTGGGCAAGAATTAATGCCTCCTTCTTGGGTAGATAGAGGAAAAATTGCTTTTTTCTTTGGTACTGAT
GATTTAGGTCGCGACATATTAAGTCGTTTAATTATGGGTACTCGTTATACCTTAGGTTCTGCTTTACTGGTTGTCTTTTC
AGTGGCAATAATAGGCGGCGCACTAGGAATTATTGCAGGACTACTGAAAGGTATTAAAGCTCGTTTTGTCGGGCATATTT
TTGATGCTTTTTTATCGTTACCTATTCTATTAATTGCCATTGTTATTTCAACATTAATGGAACCAAGTTTATGGAATGCA
ATGTTCGCAACACTCTTAGCGATATTGCCGTATTTCATCCATGCAATTTATCAAGCCATTCAACAAGAATTGAAAAAAGA
TTATGTGCTGATGTTAAAACTTGAAGGCATTTCTAACTGGGAATTATTAAAAAGCACTATTTTACCGAATATTACTGTTA
TTTATATTCAAGAAGTGGCTCGTGCTTTTGTTATAGCCGTGTTGGATATTAGCGCGTTAAGTTTTATTTCCCTTGGCGCA
CAACGACCAACCCCAGAATGGGGCGCAATGATTCGAGATTCTTTAGAACTACTCTATCTTGCACCTTGGACGGTATTACT
CCCTGGCTTTGCAATTATTTTTACTATTTTTATTAAGCATTATTTTTAG

Upstream 100 bases:

>100_bases
GCCGCAGGTGTAATTGTTATTGGTGTATGTATTATTTTGATTGATACATTCACTAAAATATTCACTTTTATACTCGATCC
ATTTAAAAAGAAAGGTTGGT

Downstream 100 bases:

>100_bases
CAATGGCTTAACTAAAACCATCAATCAACATCAAGAATAGCCTATGGCACTTTTAGACATTTGTAACCTCAATATTGAAA
TTCAAACCTCCAATGGACGT

Product: peptide ABC transporter permease protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MQNKEPDEFRESTSIFQIWLRFRQNTIALFSFYLLIALIFTALFASYLAPYADNRQFIGQELMPPSWVDRGKIAFFFGTD
DLGRDILSRLIMGTRYTLGSALLVVFSVAIIGGALGIIAGLLKGIKARFVGHIFDAFLSLPILLIAIVISTLMEPSLWNA
MFATLLAILPYFIHAIYQAIQQELKKDYVLMLKLEGISNWELLKSTILPNITVIYIQEVARAFVIAVLDISALSFISLGA
QRPTPEWGAMIRDSLELLYLAPWTVLLPGFAIIFTIFIKHYF

Sequences:

>Translated_282_residues
MQNKEPDEFRESTSIFQIWLRFRQNTIALFSFYLLIALIFTALFASYLAPYADNRQFIGQELMPPSWVDRGKIAFFFGTD
DLGRDILSRLIMGTRYTLGSALLVVFSVAIIGGALGIIAGLLKGIKARFVGHIFDAFLSLPILLIAIVISTLMEPSLWNA
MFATLLAILPYFIHAIYQAIQQELKKDYVLMLKLEGISNWELLKSTILPNITVIYIQEVARAFVIAVLDISALSFISLGA
QRPTPEWGAMIRDSLELLYLAPWTVLLPGFAIIFTIFIKHYF
>Mature_282_residues
MQNKEPDEFRESTSIFQIWLRFRQNTIALFSFYLLIALIFTALFASYLAPYADNRQFIGQELMPPSWVDRGKIAFFFGTD
DLGRDILSRLIMGTRYTLGSALLVVFSVAIIGGALGIIAGLLKGIKARFVGHIFDAFLSLPILLIAIVISTLMEPSLWNA
MFATLLAILPYFIHAIYQAIQQELKKDYVLMLKLEGISNWELLKSTILPNITVIYIQEVARAFVIAVLDISALSFISLGA
QRPTPEWGAMIRDSLELLYLAPWTVLLPGFAIIFTIFIKHYF

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=272, Percent_Identity=43.0147058823529, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1789964, Length=265, Percent_Identity=36.6037735849057, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=30.0724637681159, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787760, Length=259, Percent_Identity=30.8880308880309, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789889, Length=205, Percent_Identity=26.3414634146341, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31855; Mature: 31855

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKEPDEFRESTSIFQIWLRFRQNTIALFSFYLLIALIFTALFASYLAPYADNRQFIGQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ELMPPSWVDRGKIAFFFGTDDLGRDILSRLIMGTRYTLGSALLVVFSVAIIGGALGIIAG
HCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKGIKARFVGHIFDAFLSLPILLIAIVISTLMEPSLWNAMFATLLAILPYFIHAIYQAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QQELKKDYVLMLKLEGISNWELLKSTILPNITVIYIQEVARAFVIAVLDISALSFISLGA
HHHHHHHHEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QRPTPEWGAMIRDSLELLYLAPWTVLLPGFAIIFTIFIKHYF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQNKEPDEFRESTSIFQIWLRFRQNTIALFSFYLLIALIFTALFASYLAPYADNRQFIGQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ELMPPSWVDRGKIAFFFGTDDLGRDILSRLIMGTRYTLGSALLVVFSVAIIGGALGIIAG
HCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKGIKARFVGHIFDAFLSLPILLIAIVISTLMEPSLWNAMFATLLAILPYFIHAIYQAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QQELKKDYVLMLKLEGISNWELLKSTILPNITVIYIQEVARAFVIAVLDISALSFISLGA
HHHHHHHHEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QRPTPEWGAMIRDSLELLYLAPWTVLLPGFAIIFTIFIKHYF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]