| Definition | Haemophilus influenzae PittGG chromosome, complete genome. |
|---|---|
| Accession | NC_009567 |
| Length | 1,887,192 |
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The map label for this gene is uvrD [H]
Identifier: 148828339
GI number: 148828339
Start: 1782065
End: 1784245
Strand: Reverse
Name: uvrD [H]
Synonym: CGSHiGG_09635
Alternate gene names: 148828339
Gene position: 1784245-1782065 (Counterclockwise)
Preceding gene: 148828340
Following gene: 148828338
Centisome position: 94.54
GC content: 39.89
Gene sequence:
>2181_bases ATGGATATTTCTGAATTACTTGACGGACTCAACGATAAACAACGCGAAGCCGTAGCTGCTCCTCTTGGTAATCACTTAGT GCTAGCTGGTGCAGGCTCGGGCAAAACGCGTGTATTGACGCACCGTATTGCTTGGTTAATTGCGGTCGAAAATATTTCTG AAGGCAGCATTATGGCGGTGACGTTTACCAATAAAGCCGCAGCAGAAATGCGTCATCGTATTCAATCTACCCTTGCCAAA CACGCACAACATCAATTAGTTGGTATGTGGATTGGCACCTTCCATAGCATTGCTCATCGTTTGTTGCGAGCTCATCATTT AGATGTGGGATTGCCACAAGATTTCCAAATTTTAGATTCAGAAGATCAACTTCGTTTAATTAAACGATTATTAAAATTAC ATAATTTTGATGAAAAAGCTTTTCCGCCTAAACAGGCTTGTTGGTACATCAATAACAAAAAAGATGAAGGCTTGCGACCA AATGATATTGAAGATTTTAATGATCGCCAAGAACGTGAATGGATTAAAATTTATCAGATCTATCAAGACACTTGCGATCG CGCAGGGTTGGTCGATTTTGCTGAATTATTAATTCGGGTCTATGAATTATTTGAGAAAAAACCATTAATTTTGCAACGTT ATCAACAACGTTTTCAGCATATTTTGGTGGATGAATTTCAAGACACCAATAAAATCCAATATAAATGGATCAAAATTCTT GCTGGAAAAACAGGCCAAGTCATGATTGTGGGCGATGATGATCAATCTATATACGGTTGGCGTGGTGCACAAATAGAAAA TATCCAAAAATTCTTGAAAGATTTCAAAGCCGAAACAATTCGCCTTGAACAAAACTATCGTTCTACCGCCAATATCCTAA ACAGCGCAAATGAATTAATTGCAAACAATAGTGATCGTCTTGGTAAAAATTTATGGACAGAGGGTGAAAAAGGCGATCCT GTGGGCATCTATTCTGCCTTTAATGAATTAGATGAAGCAAAATTTGTCGCTTCACAAATTCAGGATTGGGTAGAACATGG CGGAAAACTTGATGATTGCGCTGTACTTTATCGTAGTAATAGCCAATCACGGGTTATTGAAGAAGCTTTAATTCGTTGTC AAATTCCATACCGTATTTATGGCGGTATGCGTTTCTTCGAACGTCAAGAAATTAAAGATGCGTTAGCCTATCTTCGTTTG ATTAATAATCGTCAAGATGATGCGGCTTTTGAGCGTGTAATTAATACGCCAACCCGTGGCATTGGCAACCGCACTTTAGA TATATTGCGTAACTTAACACGCGAACGCCAAATTACCTTATGGCAAGCAGTACAAGTCGCAACACAAGAAAATATGTTGG CAGGGCGAGCCTCAACAGCCTTATTACGTTTCCAAGAATTAATTAATTCACTACAACTTGATACCGCAGAAATGCCGCTT TTCGCACAAACTGATTTTGTGATTAAACATTCGGGCTTATATGAAATGTATCAACAAGAAAAAGGCGAAAAAGGCGAAGT GCGTATTGAAAATTTGGAAGAATTAGTTACCGCAACCCGTGAATTTATCAAACCTGATAATGCGGAAGAAATGACCGAAC TCACTGCCTTTTTAACGCACGCTTCCTTAGAAGCTGGCGAAGAACAAGCCTCGCCGCATCAATCTTGTGTAGAAATGATG ACGTTGCACTCTGCGAAAGGCTTAGAATTTCCTCGTGTATTTATGGTGGGCGTAGAAGAAGGATTATTCCCAAGTTTTCG TTCTTTTGAAGAACCCGGACGTTTAGAAGAAGAGCGTCGTTTAGCTTATGTCGGTATTACTCGCGCGCAGAAAAAACTGA CCATCTCTTATGCGGAAAGCCGTCGATTATATGCCAAAGAAGAACGCCATTTGCCATCACGGTTTATCGCAGAATTACCG AGAGAATGTATCCAAGAAATTCGTTTACGAGGGACAGTCACGCGTGCGATGAACCTAGCAAAAGTCGGTTCATTGTCGAA TACTAGTGCGGTCGAAAATGAATGGAAAATGGGTCAAAAAGTTAAACACGAAAAATTTGGTTTCGGCACAGTGATTAATG TGGAAGGATCTGAAAATAACACACGTTTACAAATAGCATTCCAAGCGCAAGGCATTAAATGGTTGATTGCGCATTTGGCA AAATTGGAAAAAGTGCGGTAG
Upstream 100 bases:
>100_bases TGTTCTACCCTACTTTTGATATACTCACAAATCTTATTGTTTCACAAGATAGATGGGACTATAATAACTGTAAATTTAAA CAGATTAAAGATAGTTTATG
Downstream 100 bases:
>100_bases AATTCAAGAGTATTATATTTTTACGATTAATTTCTTTGAAAAGTGCGGTGAATTTTTACCGCACTTTTATTATCTACGAG TGATGGAATGTTTAAATTTG
Product: DNA-dependent helicase II
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 726; Mature: 726
Protein sequence:
>726_residues MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAVTFTNKAAAEMRHRIQSTLAK HAQHQLVGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDSEDQLRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRP NDIEDFNDRQEREWIKIYQIYQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL AGKTGQVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELIANNSDRLGKNLWTEGEKGDP VGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSNSQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRL INNRQDDAAFERVINTPTRGIGNRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDNAEEMTELTAFLTHASLEAGEEQASPHQSCVEMM TLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERRLAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELP RECIQEIRLRGTVTRAMNLAKVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA KLEKVR
Sequences:
>Translated_726_residues MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAVTFTNKAAAEMRHRIQSTLAK HAQHQLVGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDSEDQLRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRP NDIEDFNDRQEREWIKIYQIYQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL AGKTGQVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELIANNSDRLGKNLWTEGEKGDP VGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSNSQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRL INNRQDDAAFERVINTPTRGIGNRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDNAEEMTELTAFLTHASLEAGEEQASPHQSCVEMM TLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERRLAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELP RECIQEIRLRGTVTRAMNLAKVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA KLEKVR >Mature_726_residues MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAVTFTNKAAAEMRHRIQSTLAK HAQHQLVGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDSEDQLRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRP NDIEDFNDRQEREWIKIYQIYQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL AGKTGQVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELIANNSDRLGKNLWTEGEKGDP VGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSNSQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRL INNRQDDAAFERVINTPTRGIGNRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDNAEEMTELTAFLTHASLEAGEEQASPHQSCVEMM TLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERRLAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELP RECIQEIRLRGTVTRAMNLAKVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA KLEKVR
Specific function: May process damage occurring in non-replicating regions of DNA to produce recombinational intermediates for sister strand recombinational exchange [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI2367296, Length=728, Percent_Identity=67.1703296703297, Blast_Score=1020, Evalue=0.0, Organism=Escherichia coli, GI48994965, Length=643, Percent_Identity=39.50233281493, Blast_Score=399, Evalue=1e-112, Organism=Escherichia coli, GI1789183, Length=512, Percent_Identity=22.8515625, Blast_Score=81, Evalue=3e-16, Organism=Escherichia coli, GI1787196, Length=183, Percent_Identity=28.9617486338798, Blast_Score=63, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322369, Length=731, Percent_Identity=28.7277701778386, Blast_Score=188, Evalue=2e-48, Organism=Saccharomyces cerevisiae, GI6324477, Length=668, Percent_Identity=21.5568862275449, Blast_Score=110, Evalue=9e-25,
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005753 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 83448; Mature: 83448
Theoretical pI: Translated: 6.74; Mature: 6.74
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAV CCHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCCCEEEE TFTNKAAAEMRHRIQSTLAKHAQHQLVGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDS EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC EDQLRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRPNDIEDFNDRQEREWIKIYQI CHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH YQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL HHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEE AGKTGQVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELI ECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHH ANNSDRLGKNLWTEGEKGDPVGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSN CCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECC SQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRLINNRQDDAAFERVINTPTRG CHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC IGNRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDNAEEMTELTAFLTH EECCCEEEECCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH ASLEAGEEQASPHQSCVEMMTLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERR HHHHCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCHHHE LAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELPRECIQEIRLRGTVTRAMNLA EEEEEEHHHHHEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA HHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHHH KLEKVR HHHCCC >Mature Secondary Structure MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAV CCHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCCCEEEE TFTNKAAAEMRHRIQSTLAKHAQHQLVGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDS EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC EDQLRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRPNDIEDFNDRQEREWIKIYQI CHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH YQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL HHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEE AGKTGQVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELI ECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHH ANNSDRLGKNLWTEGEKGDPVGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSN CCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECC SQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRLINNRQDDAAFERVINTPTRG CHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC IGNRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDNAEEMTELTAFLTH EECCCEEEECCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH ASLEAGEEQASPHQSCVEMMTLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERR HHHHCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCHHHE LAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELPRECIQEIRLRGTVTRAMNLA EEEEEEHHHHHEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA HHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHHH KLEKVR HHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8294031; 7542800; 3259573 [H]