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The map label for this gene is dppD [H]

Identifier: 148828338

GI number: 148828338

Start: 1780976

End: 1781977

Strand: Reverse

Name: dppD [H]

Synonym: CGSHiGG_09630

Alternate gene names: 148828338

Gene position: 1781977-1780976 (Counterclockwise)

Preceding gene: 148828339

Following gene: 148828337

Centisome position: 94.42

GC content: 40.72

Gene sequence:

>1002_bases
ATGTTTAAATTTGTATTCAAACGAATCTTAATGGTGATCCCTACTTTTATTGCCATTACTCTTATTACCTTTGCCCTTGT
GCATTTTATTCCCGGTGATCCTGTGGAAATTCTGATGGGGGAACGTGGCTTAACGGCAGAAGTACATCAACAAATGATGC
ACCAATTGGGTTTAGATTTACCTCTTTATCAGCAATATTTCCACTATATTGGCAATGTAATTCAAGGGGATTTCGGTGCA
TCGTTCCGCACTCAACAACCTGTCCTTACTGAATTTTTTACGCTTTTTCCTGCTACCGCTGAATTAGCTTTTTTTGCGTT
ATTTTGGTCATTATTAGGTGGAATAATTTTAGGCACGATTGCCGCAGTAAAAAAAGACAGTTGGATTTCTCACACCGTTA
CAGCTGCATCGCTCACAGGTTATTCTATGCCGATTTTCTGGTGGGGATTGATTTTAATTTTATATGTTTCGCCACAACTC
GGTTTGCCACAAGGTGGGCGTTTAGATAATGAATTTTGGATCGATACACCAACAGGATTTATGCTCATTGACAGCTGGCT
TTCTGGTATGCCAGGTGCCTTCGAAAATGCGGTGAAATCCTTAATTCTTCCTGCAATAGTCCTAGGCACAGTTCCTCTCG
CCATTATTACGCGTATGACACGATCTGCGATGTTGGAAGTATTAGGCGAAGATTACATTCGCACGGCTAAAGCAAAAGGT
TTAAGCTATACTCGAATTGTTATTGTTCACGCATTGCGTAATGCGTTAATTCCTGTTGTCACTGTGGTGGGATTAATTGT
AGGTCAATTGCTTTCTGGTGCAGTTCTCACAGAAACCATTTTCTCTTGGCCGGGGATTGGAAAATGGATTATTGATGCCA
TTCAAGCCCGTGATTATCCTGTGTTGCAAGGTTCTGTACTGATTATTGCGACGATTATTATTGTGGTAAATTTAACCGTC
GATTTACTTTACGGTGTGGTCAATCCGCGTATCCGTCATTAA

Upstream 100 bases:

>100_bases
AAAAGTGCGGTAGAATTCAAGAGTATTATATTTTTACGATTAATTTCTTTGAAAAGTGCGGTGAATTTTTACCGCACTTT
TATTATCTACGAGTGATGGA

Downstream 100 bases:

>100_bases
TTGTAGGAGAAATTATGTCTGACACGCCTTTAACTTTCGCGCCAAAAACACCCTTACAAGAATTTTGGTTTTACTTTAAA
CAAAATCGTGGTGCGCTAAT

Product: dipeptide transporter ATP-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MFKFVFKRILMVIPTFIAITLITFALVHFIPGDPVEILMGERGLTAEVHQQMMHQLGLDLPLYQQYFHYIGNVIQGDFGA
SFRTQQPVLTEFFTLFPATAELAFFALFWSLLGGIILGTIAAVKKDSWISHTVTAASLTGYSMPIFWWGLILILYVSPQL
GLPQGGRLDNEFWIDTPTGFMLIDSWLSGMPGAFENAVKSLILPAIVLGTVPLAIITRMTRSAMLEVLGEDYIRTAKAKG
LSYTRIVIVHALRNALIPVVTVVGLIVGQLLSGAVLTETIFSWPGIGKWIIDAIQARDYPVLQGSVLIIATIIIVVNLTV
DLLYGVVNPRIRH

Sequences:

>Translated_333_residues
MFKFVFKRILMVIPTFIAITLITFALVHFIPGDPVEILMGERGLTAEVHQQMMHQLGLDLPLYQQYFHYIGNVIQGDFGA
SFRTQQPVLTEFFTLFPATAELAFFALFWSLLGGIILGTIAAVKKDSWISHTVTAASLTGYSMPIFWWGLILILYVSPQL
GLPQGGRLDNEFWIDTPTGFMLIDSWLSGMPGAFENAVKSLILPAIVLGTVPLAIITRMTRSAMLEVLGEDYIRTAKAKG
LSYTRIVIVHALRNALIPVVTVVGLIVGQLLSGAVLTETIFSWPGIGKWIIDAIQARDYPVLQGSVLIIATIIIVVNLTV
DLLYGVVNPRIRH
>Mature_333_residues
MFKFVFKRILMVIPTFIAITLITFALVHFIPGDPVEILMGERGLTAEVHQQMMHQLGLDLPLYQQYFHYIGNVIQGDFGA
SFRTQQPVLTEFFTLFPATAELAFFALFWSLLGGIILGTIAAVKKDSWISHTVTAASLTGYSMPIFWWGLILILYVSPQL
GLPQGGRLDNEFWIDTPTGFMLIDSWLSGMPGAFENAVKSLILPAIVLGTVPLAIITRMTRSAMLEVLGEDYIRTAKAKG
LSYTRIVIVHALRNALIPVVTVVGLIVGQLLSGAVLTETIFSWPGIGKWIIDAIQARDYPVLQGSVLIIATIIIVVNLTV
DLLYGVVNPRIRH

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=60.2373887240356, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=48.0243161094225, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1787053, Length=333, Percent_Identity=39.039039039039, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1787550, Length=337, Percent_Identity=34.1246290801187, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=34.0298507462687, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1787497, Length=334, Percent_Identity=32.9341317365269, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1788504, Length=377, Percent_Identity=27.0557029177719, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36798; Mature: 36798

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFVFKRILMVIPTFIAITLITFALVHFIPGDPVEILMGERGLTAEVHQQMMHQLGLDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCHHHHHHHHHHHCCCC
PLYQQYFHYIGNVIQGDFGASFRTQQPVLTEFFTLFPATAELAFFALFWSLLGGIILGTI
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKKDSWISHTVTAASLTGYSMPIFWWGLILILYVSPQLGLPQGGRLDNEFWIDTPTGF
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHH
MLIDSWLSGMPGAFENAVKSLILPAIVLGTVPLAIITRMTRSAMLEVLGEDYIRTAKAKG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSYTRIVIVHALRNALIPVVTVVGLIVGQLLSGAVLTETIFSWPGIGKWIIDAIQARDYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
VLQGSVLIIATIIIVVNLTVDLLYGVVNPRIRH
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFKFVFKRILMVIPTFIAITLITFALVHFIPGDPVEILMGERGLTAEVHQQMMHQLGLDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCHHHHHHHHHHHCCCC
PLYQQYFHYIGNVIQGDFGASFRTQQPVLTEFFTLFPATAELAFFALFWSLLGGIILGTI
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKKDSWISHTVTAASLTGYSMPIFWWGLILILYVSPQLGLPQGGRLDNEFWIDTPTGF
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHH
MLIDSWLSGMPGAFENAVKSLILPAIVLGTVPLAIITRMTRSAMLEVLGEDYIRTAKAKG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSYTRIVIVHALRNALIPVVTVVGLIVGQLLSGAVLTETIFSWPGIGKWIIDAIQARDYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
VLQGSVLIIATIIIVVNLTVDLLYGVVNPRIRH
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]