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The map label for this gene is holA [H]

Identifier: 148828100

GI number: 148828100

Start: 1511520

End: 1512554

Strand: Direct

Name: holA [H]

Synonym: CGSHiGG_08180

Alternate gene names: 148828100

Gene position: 1511520-1512554 (Clockwise)

Preceding gene: 148828099

Following gene: 148828105

Centisome position: 80.09

GC content: 36.33

Gene sequence:

>1035_bases
ATGAACCGCATTTTTCCAGAGCAACTAAATCATCATCTTGCGCAAGGCTTGGCTAGAGTTTATCTCTTGCAAGGGCAAGA
TCCTTTATTACTTAGTGAAACTGAGGATACACTTTGTCAAGTGGCAAACCAGCAAGGTTTTGATGAAAAAAATACTATTC
AGATTGATAGCCAAACTGATTGGGCGCAACTTATAGAATCTTGTCAATCTATAGGATTGTTTTTTAGTAAACAAATACTA
AGCTTGAATTTACCTGAAAATTTCACCGCACTTTTGCAGAAAAATCTGCAAGAACTTATATCCGTATTGCATAAAGATGT
CTTGCTTATTTTACAGGTAGCAAAATTGACTAAAGGGATTGAAAAGCAAACGTGGTTTATTACACTTAATCAATATGAAC
CAAATACAATACTGATAAATTGTCAAACACCGACGGTAGAAAACTTACCACGTTGGGTAAAAAATCGTACCAAAGCAATG
GGATTAGACGCTGACAACGAAGCAATCCAACAACTTTGTTATAGTTATGAAAATAACCTGCTCGCACTCAAACAAGCTCT
GCAGCTTTTAGATTTGCTCTATCCTGACCATAAACTTAACTACAATCGTGTTATTAGCGTGGTGGAACAATCCTCAATTT
TTACACCATTTCAATGGATTGATGCGTTGCTTGTTGGAAAGGCAAATCGTGCTAAACGTATTTTAAAAGGTTTACAAGCT
GAAGATGTGCAACCTGTTATTTTATTACGCACACTACAGCGAGAATTATTTACGTTGCTTGAACTCACAAAACCACAGCA
ACGTATTGTGACAACAGAAAAACTTCCAACTCAACAAATTAAGACTGAATTTGACCGTCTAAAAATCTGGCAAAATCGCC
GACCGCTCTTTTTAAGCGCGATTCAACGTTTAACTTACCAGACTCTCTACGAAATTATCCAAGAGCTTGCCAATATTGAA
CGCCTTGCTAAACAAGAATTTAGTGATGAAGTGTGGATTAAACTCGCTGATTTATCTGTAAAAATTTGTTTGTAG

Upstream 100 bases:

>100_bases
CAGAAGAACGAGAGGTAATTTGGAATGATATGCGCGAGCAAGTAGCGCGTCAATTAATCGTAAAAATAATTGCGTTACAA
AATCAAATAAAAAGGAAATA

Downstream 100 bases:

>100_bases
TCACAAGGCAAATAAAATAGACAATATTGAAATAAGATTTTTGATAAAAAAGAAATTTTTTGCTGGAAAAATGGTCCCCC
CTACCGGACTTGAACCAGTG

Product: DNA polymerase III subunit delta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNRIFPEQLNHHLAQGLARVYLLQGQDPLLLSETEDTLCQVANQQGFDEKNTIQIDSQTDWAQLIESCQSIGLFFSKQIL
SLNLPENFTALLQKNLQELISVLHKDVLLILQVAKLTKGIEKQTWFITLNQYEPNTILINCQTPTVENLPRWVKNRTKAM
GLDADNEAIQQLCYSYENNLLALKQALQLLDLLYPDHKLNYNRVISVVEQSSIFTPFQWIDALLVGKANRAKRILKGLQA
EDVQPVILLRTLQRELFTLLELTKPQQRIVTTEKLPTQQIKTEFDRLKIWQNRRPLFLSAIQRLTYQTLYEIIQELANIE
RLAKQEFSDEVWIKLADLSVKICL

Sequences:

>Translated_344_residues
MNRIFPEQLNHHLAQGLARVYLLQGQDPLLLSETEDTLCQVANQQGFDEKNTIQIDSQTDWAQLIESCQSIGLFFSKQIL
SLNLPENFTALLQKNLQELISVLHKDVLLILQVAKLTKGIEKQTWFITLNQYEPNTILINCQTPTVENLPRWVKNRTKAM
GLDADNEAIQQLCYSYENNLLALKQALQLLDLLYPDHKLNYNRVISVVEQSSIFTPFQWIDALLVGKANRAKRILKGLQA
EDVQPVILLRTLQRELFTLLELTKPQQRIVTTEKLPTQQIKTEFDRLKIWQNRRPLFLSAIQRLTYQTLYEIIQELANIE
RLAKQEFSDEVWIKLADLSVKICL
>Mature_344_residues
MNRIFPEQLNHHLAQGLARVYLLQGQDPLLLSETEDTLCQVANQQGFDEKNTIQIDSQTDWAQLIESCQSIGLFFSKQIL
SLNLPENFTALLQKNLQELISVLHKDVLLILQVAKLTKGIEKQTWFITLNQYEPNTILINCQTPTVENLPRWVKNRTKAM
GLDADNEAIQQLCYSYENNLLALKQALQLLDLLYPDHKLNYNRVISVVEQSSIFTPFQWIDALLVGKANRAKRILKGLQA
EDVQPVILLRTLQRELFTLLELTKPQQRIVTTEKLPTQQIKTEFDRLKIWQNRRPLFLSAIQRLTYQTLYEIIQELANIE
RLAKQEFSDEVWIKLADLSVKICL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the b

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786859, Length=344, Percent_Identity=44.4767441860465, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39893; Mature: 39893

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIFPEQLNHHLAQGLARVYLLQGQDPLLLSETEDTLCQVANQQGFDEKNTIQIDSQTD
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCCEEECCCCH
WAQLIESCQSIGLFFSKQILSLNLPENFTALLQKNLQELISVLHKDVLLILQVAKLTKGI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EKQTWFITLNQYEPNTILINCQTPTVENLPRWVKNRTKAMGLDADNEAIQQLCYSYENNL
CCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCH
LALKQALQLLDLLYPDHKLNYNRVISVVEQSSIFTPFQWIDALLVGKANRAKRILKGLQA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCC
EDVQPVILLRTLQRELFTLLELTKPQQRIVTTEKLPTQQIKTEFDRLKIWQNRRPLFLSA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHH
IQRLTYQTLYEIIQELANIERLAKQEFSDEVWIKLADLSVKICL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCEEEEEC
>Mature Secondary Structure
MNRIFPEQLNHHLAQGLARVYLLQGQDPLLLSETEDTLCQVANQQGFDEKNTIQIDSQTD
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCCEEECCCCH
WAQLIESCQSIGLFFSKQILSLNLPENFTALLQKNLQELISVLHKDVLLILQVAKLTKGI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EKQTWFITLNQYEPNTILINCQTPTVENLPRWVKNRTKAMGLDADNEAIQQLCYSYENNL
CCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCH
LALKQALQLLDLLYPDHKLNYNRVISVVEQSSIFTPFQWIDALLVGKANRAKRILKGLQA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCC
EDVQPVILLRTLQRELFTLLELTKPQQRIVTTEKLPTQQIKTEFDRLKIWQNRRPLFLSA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHH
IQRLTYQTLYEIIQELANIERLAKQEFSDEVWIKLADLSVKICL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]